Published in Am J Respir Crit Care Med on July 21, 2004
An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.73
Ghrelin for cachexia. J Cachexia Sarcopenia Muscle (2010) 1.12
Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial. PLoS One (2012) 0.96
TNF-α is associated with loss of lean body mass only in already cachectic COPD patients. Respir Res (2012) 0.88
Gut hormones, appetite suppression and cachexia in patients with pulmonary TB. PLoS One (2013) 0.88
Integrating GHS into the Ghrelin System. Int J Pept (2010) 0.88
Ghrelin and cachexia: will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes? Mol Cell Endocrinol (2011) 0.84
Neuropeptides in the pathophysiology and treatment of cachexia. Curr Opin Support Palliat Care (2010) 0.82
Ghrelin Inhibits Interleukin-6 Production Induced by Cigarette Smoke Extract in the Bronchial Epithelial Cell Via NF-κB Pathway. Inflammation (2016) 0.82
Effect of octanoic acid-rich formula on plasma ghrelin levels in cachectic patients with chronic respiratory disease. Nutr J (2009) 0.81
Effects of nutraceutical diet integration, with coenzyme Q10 (Q-Ter multicomposite) and creatine, on dyspnea, exercise tolerance, and quality of life in COPD patients with chronic respiratory failure. Multidiscip Respir Med (2013) 0.80
Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment. BMC Pulm Med (2013) 0.80
Cachexia in chronic obstructive pulmonary disease: new insights and therapeutic perspective. J Cachexia Sarcopenia Muscle (2015) 0.79
Association between serum interleukin-6 concentrations and chronic obstructive pulmonary disease: a systematic review and meta-analysis. PeerJ (2015) 0.78
Undernutrition in patients with COPD and its treatment. Nutrients (2013) 0.78
Energy metabolism and nutritional status in hospitalized patients with lung cancer. J Clin Biochem Nutr (2016) 0.78
Malnutrition Markers and Serum Ghrelin Levels in Hemodialysis Patients. Int Sch Res Notices (2014) 0.75
Association of plasma adiponectin levels with cellular hydration state measured using bioelectrical impedance analysis in patients with COPD. Int J Chron Obstruct Pulmon Dis (2012) 0.75
Plasma orexin-A and ghrelin levels in patients with chronic obstructive pulmonary disease: Interaction with nutritional status and body composition. Exp Ther Med (2014) 0.75
Increased circulating obestatin in patients with chronic obstructive pulmonary disease. Multidiscip Respir Med (2014) 0.75
Evaluation of ghrelin level and appetite regulation in patients with acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2014) 0.75
Therapeutic Potential of Targeting the Ghrelin Pathway. Int J Mol Sci (2017) 0.75
Antifibrotic activity of acylated and unacylated ghrelin. Int J Endocrinol (2015) 0.75
Acylation of ghrelin is increased in heart failure and decreases post heart transplantation. Scand Cardiovasc J (2014) 0.75
Ghrelin: structure and function. Physiol Rev (2005) 4.74
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat Med (2006) 4.53
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature (2010) 3.55
U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat Struct Biol (2002) 3.25
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology (2002) 3.17
Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy. Circulation (2005) 3.10
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study. J Clin Oncol (2011) 3.10
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J (2008) 3.08
Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science (2010) 3.07
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
Unblinded pilot study of autologous transplantation of bone marrow mononuclear cells in patients with thromboangiitis obliterans. Circulation (2006) 2.81
Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol Cell Biol (2005) 2.80
Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci (2003) 2.78
Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol (2004) 2.69
Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab (2002) 2.62
Crystal structure of the human centromeric nucleosome containing CENP-A. Nature (2011) 2.42
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. Nat Cell Biol (2006) 2.37
Broad chromosomal domains of histone modification patterns in C. elegans. Genome Res (2010) 2.36
The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet (2010) 2.30
Intravascular ultrasound evaluation of coronary plaque regression by low density lipoprotein-apheresis in familial hypercholesterolemia: the Low Density Lipoprotein-Apheresis Coronary Morphology and Reserve Trial (LACMART). J Am Coll Cardiol (2002) 2.26
Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem (2004) 2.26
The functional organization of mitochondrial genomes in human cells. BMC Biol (2004) 2.20
A wave of nascent transcription on activated human genes. Proc Natl Acad Sci U S A (2009) 2.18
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Nat Cell Biol (2010) 2.18
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Plasma viral microRNA profiles reveal potential biomarkers for chronic active Epstein-Barr virus infection. J Infect Dis (2013) 2.11
Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents. Diabetes (2004) 2.04
Report from the Working Group of the Molecular Biology Society of Japan for the investigation of fraud in research papers. Genes Cells (2009) 2.02
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Long QT syndrome with compound mutations is associated with a more severe phenotype: a Japanese multicenter study. Heart Rhythm (2010) 2.00
Systemic cytokine responses in patients with influenza-associated encephalopathy. J Infect Dis (2003) 1.98
Can magnifying endoscopy with narrow band imaging be useful for low grade adenomas in preoperative biopsy specimens? Gastric Cancer (2012) 1.95
Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion. Diabetes (2002) 1.95
Treatment of cachexia with ghrelin in patients with COPD. Chest (2005) 1.87
Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells. Circulation (2003) 1.86
Airflow limitation in smokers is associated with subclinical atherosclerosis. Am J Respir Crit Care Med (2008) 1.83
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation (2004) 1.79
Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana. Plant Cell Physiol (2008) 1.76
Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol (Oxf) (2002) 1.76
A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats. Am J Respir Crit Care Med (2003) 1.74
H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells. BMC Genomics (2012) 1.73
Gene and protein expression analysis of mesenchymal stem cells derived from rat adipose tissue and bone marrow. Circ J (2011) 1.70
Failure to prevent progressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valve. Circulation (2003) 1.69
Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology (2006) 1.67
Ghrelin, a novel growth hormone-releasing peptide, in the treatment of cardiopulmonary-associated cachexia. Intern Med (2006) 1.66
Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol (2005) 1.65
Oxidative stress in obstructive sleep apnea. Chest (2005) 1.65
Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema. Cardiovasc Res (2008) 1.64
Sex hormone and gender difference--role of testosterone on male predominance in Brugada syndrome. J Cardiovasc Electrophysiol (2007) 1.63
Electrophysiologic characteristics and implications of induced ventricular fibrillation in symptomatic patients with Brugada syndrome. J Am Coll Cardiol (2002) 1.63
Images in cardiovascular medicine. "Arteries within the artery" after Kawasaki disease: a lotus root appearance by intravascular ultrasound. Circulation (2002) 1.61
Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles. Heart Rhythm (2010) 1.61
Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions. FEBS Lett (2007) 1.60
Nasal continuous positive airway pressure improves quality of life in obesity hypoventilation syndrome. Sleep Breath (2003) 1.59
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell (2013) 1.59
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J (2010) 1.58
Ghrelin concentration in cord and neonatal blood: relation to fetal growth and energy balance. J Clin Endocrinol Metab (2003) 1.56
Effect of serum leptin levels on hypercapnic ventilatory response in obstructive sleep apnea. Respiration (2007) 1.56
Impact of severe earthquake on the occurrence of acute coronary syndrome and stroke in a rural area of Japan. Circ J (2009) 1.55
Comparison of angiogenic potency between mesenchymal stem cells and mononuclear cells in a rat model of hindlimb ischemia. Cardiovasc Res (2005) 1.55
Clinical and virological characteristics of 15 patients with chronic active Epstein-Barr virus infection treated with hematopoietic stem cell transplantation. Clin Infect Dis (2008) 1.54
Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose. Clin Sci (Lond) (2002) 1.54
Diagnostic value of epinephrine test for genotyping LQT1, LQT2, and LQT3 forms of congenital long QT syndrome. Heart Rhythm (2004) 1.53
Inhibitory effect of C-type natriuretic peptide (CNP) on cultured cardiac myocyte hypertrophy: interference between CNP and endothelin-1 signaling pathways. Endocrinology (2004) 1.53
Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome. Diabetes Res Clin Pract (2007) 1.52
Identification and characterization of a novel type of membrane-associated prostaglandin E synthase. Biochem Biophys Res Commun (2002) 1.52
Exome sequencing in suspected monogenic dyslipidemias. Circ Cardiovasc Genet (2015) 1.51
Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cells. Stem Cells (2007) 1.51
An enhanced device for transluminal retrieval of vascular stents without surgical procedures: experimental studies. J Interv Cardiol (2010) 1.50
Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody. Circ Cardiovasc Genet (2015) 1.50
Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene. Circ Res (2002) 1.49
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. Nucleic Acids Res (2011) 1.49
Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. Am Heart J (2005) 1.49
Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan. Brain Dev (2003) 1.48
Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension. J Appl Physiol (1985) (2011) 1.48
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48