Published in Nat Struct Biol on November 01, 2002
Multiple links between transcription and splicing. RNA (2004) 4.90
MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. Mol Cell Biol (2003) 2.90
DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation. Nucleic Acids Res (2006) 2.87
A quantitative analysis of intron effects on mammalian gene expression. RNA (2003) 2.80
Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor. EMBO J (2004) 2.76
TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. Mol Cell (2009) 2.61
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. PLoS Biol (2011) 2.58
Promoter proximal splice sites enhance transcription. Genes Dev (2002) 2.46
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RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites. Cell (2014) 2.13
Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. J Biomed Sci (2004) 2.11
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J (2004) 2.06
Functional coupling of RNAP II transcription to spliceosome assembly. Genes Dev (2006) 1.98
Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila. Genes Dev (2011) 1.87
Functional interactions between the transcription and mRNA 3' end processing machineries mediated by Ssu72 and Sub1. Genes Dev (2003) 1.79
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Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium. Blood (2013) 1.45
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The Drosophila P68 RNA helicase regulates transcriptional deactivation by promoting RNA release from chromatin. Genes Dev (2006) 1.36
Nuclear coupling: RNA processing reaches back to transcription. Nat Struct Biol (2002) 1.30
Transcriptional regulation of human small nuclear RNA genes. Biochim Biophys Acta (2008) 1.25
Role of the C-terminal domain of RNA polymerase II in U2 snRNA transcription and 3' processing. Mol Cell Biol (2004) 1.22
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22
Divergent transcription: a driving force for new gene origination? Cell (2013) 1.20
RNA helicases in splicing. RNA Biol (2012) 1.13
Cotranscriptional splicing efficiency differs dramatically between Drosophila and mouse. RNA (2012) 1.12
The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes. Genes Dev (2005) 1.10
Human U1 snRNA forms a new chromatin-associated snRNP with TAF15. EMBO Rep (2009) 1.08
HIV-1, human interaction database: current status and new features. Nucleic Acids Res (2014) 1.02
Differentially expressed, variant U1 snRNAs regulate gene expression in human cells. Genome Res (2012) 1.02
Role for gene looping in intron-mediated enhancement of transcription. Proc Natl Acad Sci U S A (2012) 1.00
Mechanistic insights into chromosome-wide silencing in X inactivation. Hum Genet (2011) 1.00
RNA binding and intramolecular interactions modulate the regulation of gene expression by nuclear factor 110. RNA (2003) 0.99
Where splicing joins chromatin. Nucleus (2011) 0.98
Promoter-proximal polyadenylation sites reduce transcription activity. Genes Dev (2012) 0.98
Functional studies on the ATM intronic splicing processing element. Nucleic Acids Res (2005) 0.97
Function and assembly of a chromatin-associated RNase P that is required for efficient transcription by RNA polymerase I. PLoS One (2008) 0.94
Allele-specific recognition of the 3' splice site of INS intron 1. Hum Genet (2010) 0.94
Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes. Mol Cell Biol (2008) 0.92
A global comparison between nuclear and cytosolic transcriptomes reveals differential compartmentalization of alternative transcript isoforms. Nucleic Acids Res (2009) 0.91
The transcriptional transactivator Tat selectively regulates viral splicing. Nucleic Acids Res (2009) 0.88
Efficient transcription through an intron requires the binding of an Sm-type U1 snRNP with intact stem loop II to the splice donor. Nucleic Acids Res (2010) 0.86
Improvement of SMN2 pre-mRNA processing mediated by exon-specific U1 small nuclear RNA. Am J Hum Genet (2014) 0.84
RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing. Genet Res Int (2011) 0.84
Novel insight into the non-coding repertoire through deep sequencing analysis. Nucleic Acids Res (2012) 0.84
Nova1 is a master regulator of alternative splicing in pancreatic beta cells. Nucleic Acids Res (2014) 0.83
Why eukaryotic cells use introns to enhance gene expression: splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity. Biol Direct (2011) 0.82
Pre-mRNA splicing is a determinant of nucleosome organization. PLoS One (2013) 0.82
Riboactivators: transcription activation by noncoding RNA. Crit Rev Biochem Mol Biol (2009) 0.81
Transcription control by long non-coding RNAs. Transcription (2012) 0.80
Dramatically reduced spliceosome in Cyanidioschyzon merolae. Proc Natl Acad Sci U S A (2015) 0.80
A new function of the splicing factor SRSF2 in the control of E2F1-mediated cell cycle progression in neuroendocrine lung tumors. Cell Cycle (2013) 0.80
U1 snRNA rewrites the "script". Cell (2012) 0.79
Ribonucleoprotein particles of bacterial small non-coding RNA IsrA (IS61 or McaS) and its interaction with RNA polymerase core may link transcription to mRNA fate. Nucleic Acids Res (2015) 0.78
An investigation of a role for U2 snRNP spliceosomal components in regulating transcription. PLoS One (2011) 0.78
Introduction to cotranscriptional RNA splicing. Methods Mol Biol (2014) 0.78
What happens at or after transcription: Insights into circRNA biogenesis and function. Transcription (2015) 0.78
The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. J Biol Chem (2015) 0.77
Structural biology: Spliceosome subunit revealed. Nature (2009) 0.76
Suppressor of sable, a putative RNA-processing protein, functions at the level of transcription. Mol Cell Biol (2004) 0.76
In new company: U1 snRNA associates with TAF15. EMBO Rep (2009) 0.76
Long noncoding RNAs as metazoan developmental regulators. Chromosome Res (2013) 0.76
The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J (2017) 0.75
Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells. Nucleic Acids Res (2016) 0.75
The Spliceosomal Protein SF3B5 is a Novel Component of Drosophila SAGA that Functions in Gene Expression Independent of Splicing. J Mol Biol (2016) 0.75
Active 5' splice sites regulate the biogenesis efficiency of Arabidopsis microRNAs derived from intron-containing genes. Nucleic Acids Res (2016) 0.75
Comparative profiling of microRNAs in the winged and wingless English grain aphid, Sitobion avenae (F.) (Homoptera: Aphididae). Sci Rep (2016) 0.75
A systems view of the protein expression process. Syst Synth Biol (2011) 0.75
Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes. Sci Rep (2016) 0.75
Intron-Mediated Enhancement: A Tool for Heterologous Gene Expression in Plants? Front Plant Sci (2017) 0.75
Integrating mRNA processing with transcription. Cell (2002) 9.74
Pre-mRNA processing reaches back to transcription and ahead to translation. Cell (2009) 7.45
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature (2007) 5.57
Cracking the RNA polymerase II CTD code. Trends Genet (2008) 4.00
Cohesin complex promotes transcriptional termination between convergent genes in S. pombe. Cell (2008) 3.60
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature (2010) 3.55
Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites. Nature (2004) 3.52
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression. Science (2007) 3.36
Gene loops juxtapose promoters and terminators in yeast. Nat Genet (2004) 3.33
Polypyrimidine tract binding protein modulates efficiency of polyadenylation. Mol Cell Biol (2004) 3.28
Primary microRNA transcripts are processed co-transcriptionally. Nat Struct Mol Biol (2008) 3.21
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study. J Clin Oncol (2011) 3.10
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J (2008) 3.08
Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science (2010) 3.07
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
Transcriptional collision between convergent genes in budding yeast. Proc Natl Acad Sci U S A (2002) 2.84
Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci (2003) 2.78
Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol Cell (2011) 2.59
Pause sites promote transcriptional termination of mammalian RNA polymerase II. Mol Cell Biol (2006) 2.56
Gene loops enhance transcriptional directionality. Science (2012) 2.50
Exon tethering in transcription by RNA polymerase II. Mol Cell (2006) 2.47
Promoter proximal splice sites enhance transcription. Genes Dev (2002) 2.46
Crystal structure of the human centromeric nucleosome containing CENP-A. Nature (2011) 2.42
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. Nat Cell Biol (2006) 2.37
Broad chromosomal domains of histone modification patterns in C. elegans. Genome Res (2010) 2.36
The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet (2010) 2.30
Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol (2008) 2.27
Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem (2004) 2.26
Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex. Genes Dev (2009) 2.24
The functional organization of mitochondrial genomes in human cells. BMC Biol (2004) 2.20
A wave of nascent transcription on activated human genes. Proc Natl Acad Sci U S A (2009) 2.18
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Nat Cell Biol (2010) 2.18
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 2.14
Plasma viral microRNA profiles reveal potential biomarkers for chronic active Epstein-Barr virus infection. J Infect Dis (2013) 2.11
Report from the Working Group of the Molecular Biology Society of Japan for the investigation of fraud in research papers. Genes Cells (2009) 2.02
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Systemic cytokine responses in patients with influenza-associated encephalopathy. J Infect Dis (2003) 1.98
Updating the RNA polymerase CTD code: adding gene-specific layers. Trends Genet (2012) 1.95
Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex. J Virol (2006) 1.93
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana. Plant Cell Physiol (2008) 1.76
A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats. Am J Respir Crit Care Med (2003) 1.74
H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells. BMC Genomics (2012) 1.73
P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes. EMBO J (2005) 1.66
Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination. Nature (2004) 1.66
Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol (2005) 1.65
Oxidative stress in obstructive sleep apnea. Chest (2005) 1.65
Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination. Genes Dev (2008) 1.64
Nasal continuous positive airway pressure improves quality of life in obesity hypoventilation syndrome. Sleep Breath (2003) 1.59
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell (2013) 1.59
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J (2010) 1.58
Effect of serum leptin levels on hypercapnic ventilatory response in obstructive sleep apnea. Respiration (2007) 1.56
Clinical and virological characteristics of 15 patients with chronic active Epstein-Barr virus infection treated with hematopoietic stem cell transplantation. Clin Infect Dis (2008) 1.54
Life-threatening hyperkalaemia following therapeutic barbiturate coma. Intensive Care Med (2002) 1.54
CPFP: a central proteomics facilities pipeline. Bioinformatics (2010) 1.53
The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J Leukoc Biol (2010) 1.50
Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae. Mol Cell (2009) 1.50
Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals. Mol Cell (2008) 1.50
The C-terminal domain of pol II and a DRB-sensitive kinase are required for 3' processing of U2 snRNA. EMBO J (2003) 1.50
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. Nucleic Acids Res (2011) 1.49
Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan. Brain Dev (2003) 1.48
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48
The constitutive centromere component CENP-50 is required for recovery from spindle damage. Mol Cell Biol (2005) 1.44
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor. Clin Cancer Res (2007) 1.41
Two cases of endobronchial neurilemmoma and review of the literature in Japan. Intern Med (2003) 1.41
Expression of human snRNA genes from beginning to end. Biochem Soc Trans (2008) 1.39
The affinity of hemoglobin for oxygen affects ventilatory responses in mutant mice with Presbyterian hemoglobinopathy. Am J Physiol Regul Integr Comp Physiol (2003) 1.39
Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension. Circ J (2013) 1.39
The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export. J Biol Chem (2007) 1.38
Amphotericin B-induced nephrogenic diabetes insipidus in a case of cryptococcemia. Intern Med (2005) 1.38
Allelic variation in normal human FBN1 expression in a family with Marfan syndrome: a potential modifier of phenotype? Hum Mol Genet (2003) 1.37
The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain. J Biol Chem (2010) 1.33
Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway. Nat Struct Mol Biol (2013) 1.33
Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T. Proc Natl Acad Sci U S A (2010) 1.32
Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage. Mol Cell (2013) 1.30
Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. EMBO J (2012) 1.30
Comparative evaluation of label-free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline. Proteomics (2011) 1.30
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres. Dev Cell (2013) 1.30
A novel myc target gene, mina53, that is involved in cell proliferation. J Biol Chem (2002) 1.29
RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA. Nat Struct Mol Biol (2007) 1.29
Arabidopsis HDA6 regulates locus-directed heterochromatin silencing in cooperation with MET1. PLoS Genet (2011) 1.27
Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase. J Cell Biol (2009) 1.26
Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast. Biochim Biophys Acta (2012) 1.24
Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis. Am J Pathol (2009) 1.24
A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans. Genome Biol (2007) 1.24
Chromatin structure is implicated in "late" elongation checkpoints on the U2 snRNA and beta-actin genes. Mol Cell Biol (2009) 1.23
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome. EMBO J (2010) 1.23
Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence. Genes Dev (2013) 1.23
Trans-generational epigenetic regulation of C. elegans primordial germ cells. Epigenetics Chromatin (2010) 1.22
Transduction of RNA-directed DNA methylation signals to repressive histone marks in Arabidopsis thaliana. EMBO J (2009) 1.21
Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p. Proc Natl Acad Sci U S A (2004) 1.20
Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes. Mol Cell (2011) 1.20
Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum. J Biol Chem (2008) 1.19
Herpes simplex virus type 1 UL51 protein is involved in maturation and egress of virus particles. J Virol (2005) 1.19