Published in Mol Cell Biol on August 01, 2004
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury. J Biol Chem (2010) 1.61
Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. J Exp Med (2006) 1.19
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. J Exp Med (2007) 1.16
GATA-4 is required for sex steroidogenic cell development in the fetal mouse. Dev Dyn (2007) 1.06
Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases. Biochem Biophys Res Commun (2011) 1.00
Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice. Am J Pathol (2008) 0.98
Transcriptome profiling of granulosa cells from bovine ovarian follicles during atresia. BMC Genomics (2014) 0.97
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia. Am J Physiol Lung Cell Mol Physiol (2009) 0.97
HCV tumor promoting effect is dependent on host genetic background. PLoS One (2009) 0.95
Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.89
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate. Toxicol Appl Pharmacol (2007) 0.85
Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats. Am J Physiol Gastrointest Liver Physiol (2009) 0.84
Cysteamine, the molecule used to treat cystinosis, potentiates the antimalarial efficacy of artemisinin. Antimicrob Agents Chemother (2010) 0.84
Global gene expression in granulosa cells of growing, plateau and atretic dominant follicles in cattle. Reprod Biol Endocrinol (2015) 0.83
Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium. Exp Parasitol (2010) 0.82
Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS One (2012) 0.82
Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake. Hypertens Res (2015) 0.81
The TRAF6-NF kappa B signaling pathway in autoimmunity: not just inflammation. Arthritis Res Ther (2005) 0.80
Role of Oxidative Stress in Drug-Induced Kidney Injury. Int J Mol Sci (2016) 0.79
Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses. Biochim Biophys Acta (2016) 0.79
Dietary heme-mediated PPARα activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon. PLoS One (2012) 0.79
Analysis of vanin-1 upregulation and lipid accumulation in hepatocytes in response to a high-fat diet and free fatty acids. J Clin Biochem Nutr (2012) 0.78
Developmental ethanol exposure leads to dysregulation of lipid metabolism and oxidative stress in Drosophila. G3 (Bethesda) (2014) 0.78
The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function. PLoS Genet (2014) 0.78
Sox17 regulates liver lipid metabolism and adaptation to fasting. PLoS One (2014) 0.77
High molecular weight isoforms of growth hormone in cells of the immune system. Cell Immunol (2011) 0.77
Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes. Sci Rep (2016) 0.76
Glutathione metabolism in Candida albicans resistant strains to fluconazole and micafungin. PLoS One (2014) 0.76
Increased human dermal microvascular endothelial cell survival induced by cysteamine. J Inherit Metab Dis (2013) 0.76
VNN1 overexpression is associated with poor response to preoperative chemoradiotherapy and adverse prognosis in patients with rectal cancers. Am J Transl Res (2016) 0.76
Stable isotope gas chromatography-tandem mass spectrometry determination of aminoethylcysteine ketimine decarboxylated dimer in biological samples. Anal Biochem (2012) 0.76
A Pharmacogenetic Discovery: Cystamine Protects Against Haloperidol-Induced Toxicity and Ischemic Brain Injury. Genetics (2016) 0.75
Synthesis, Crystal Structure, Spectroscopic Properties, and Interaction with Ct-DNA of Zn(II) with 2-Aminoethanethiol Hydrochloride Ligand. Bioinorg Chem Appl (2016) 0.75
Proteomic Analysis of Non-depleted Serum Proteins from Bottlenose Dolphins Uncovers a High Vanin-1 Phenotype. Sci Rep (2016) 0.75
Vanin-1 expression and methylation discriminate pediatric asthma corticosteroid treatment response. J Allergy Clin Immunol (2015) 0.75
Movento influences development of granulosa cells and ovarian follicles and FoxO1 and Vnn1 gene expression in BALB/c mice. Iran J Basic Med Sci (2016) 0.75
Characterization of exosomal release in bovine endometrial intercaruncular stromal cells. Reprod Biol Endocrinol (2016) 0.75
Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria. Mamm Genome (2011) 0.75
Real time quantitative PCR. Genome Res (1996) 35.79
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med (2001) 11.92
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem (1991) 6.16
Assays for differentiation of glutathione S-transferases. Methods Enzymol (1981) 5.69
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic Res (1999) 4.34
Functional antioxidant responsive elements. Proc Natl Acad Sci U S A (1997) 4.05
TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity (2001) 3.20
Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem Pharmacol (2000) 2.59
Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence. J Biol Chem (1997) 2.57
TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev (2001) 2.35
Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proc Natl Acad Sci U S A (2003) 2.21
Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects? Oncogene (2001) 1.68
Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic Biol Med (2000) 1.61
Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J Immunol (2002) 1.56
Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements. J Biol Chem (2002) 1.56
Regulation of gamma-glutamylcysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defenses. Free Radic Res (2000) 1.52
Glutathione biosynthesis; gamma-glutamylcysteine synthetase from rat kidney. Methods Enzymol (1985) 1.50
Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene. Biochem Pharmacol (2000) 1.43
Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter. J Biol Chem (1996) 1.37
Radioprotection by glutathione ester: transport of glutathione ester into human lymphoid cells and fibroblasts. Proc Natl Acad Sci U S A (1984) 1.35
Inhibition of gamma-glutamylcysteine synthetase by cystamine: an approach to a therapy of 5-oxoprolinuria (pyroglutamic aciduria). Biochem Biophys Res Commun (1977) 1.34
Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice. FEBS Lett (2000) 1.32
Transport of glutathione diethyl ester into human cells. Proc Natl Acad Sci U S A (1993) 1.16
Monitoring changes in gene expression in renal ischemia-reperfusion in the rat. Kidney Int (2002) 1.16
Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. Immunogenetics (2001) 1.15
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores. J Clin Invest (2004) 1.13
Morphological aspects of ionizing radiation response of small intestine. Micron (2002) 1.12
Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing. Immunity (1996) 1.11
Postischemic renal oxidative stress induces inflammatory response through PAF and oxidized phospholipids. Prevention by antioxidant treatment. FASEB J (2002) 1.10
Is pantetheinase the actual identity of mouse and human vanin-1 proteins? FEBS Lett (1999) 1.06
Biphasic pattern of thymus regeneration after whole-body irradiation. J Exp Med (1969) 1.05
The enzymatic breakdown of pantethine to pantothenic acid and cystamine. Eur J Biochem (1970) 1.02
Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J Biol Chem (2002) 1.02
Activation of primary human T-lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-kappa B. Cell Growth Differ (1993) 1.01
Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium. Cytokines Cell Mol Ther (2000) 1.01
Review of the toxicology of paraquat (1,1'-dimethyl-4,4'-bipyridinium chloride). Clin Toxicol (1979) 0.95
Transient infiltration of neutrophils into the thymus in association with apoptosis induced by whole-body X-irradiation. J Leukoc Biol (2000) 0.94
Inactivation of human gamma-glutamylcysteine synthetase by cystamine. Demonstration and quantification of enzyme-ligand complexes. J Biol Chem (1978) 0.91
The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production. Biochem Pharmacol (2002) 0.90
An ESTs description of the new Vanin gene family conserved from fly to human. Immunogenetics (1999) 0.89
The expanding network of redox signaling: new observations, complexities, and perspectives. J Clin Invest (2003) 0.89
Thymocytes and RelB-dependent medullary epithelial cells provide growth-promoting and organization signals, respectively, to thymic medullary stromal cells. Eur J Immunol (1997) 0.88
Prior induction of heme oxygenase-1 with glutathione depletor ameliorates the renal ischemia and reperfusion injury in the rat. FEBS Lett (2002) 0.88
Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6. Genomics (1998) 0.81
Inflammatory and anti-inflammatory cytokines regulate the recovery from sublethal X irradiation in rat thymus. Radiat Res (2002) 0.79
Glutathione peroxidase, glutathione reductase, glutathione S-transferase, and gamma-glutamyltranspeptidase activities in the human early pregnancy placenta. Biochem Med (1983) 0.79
Semiquantitative morphological analysis of stromal cells in the irradiated and recovering rat thymus. Arch Histol Cytol (2000) 0.78
Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature (1994) 2.63
The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur J Immunol (2000) 2.58
Bacterial colonization of neonates admitted to an intensive care environment. J Pediatr (1978) 2.24
Differential gene expression in the murine thymus assayed by quantitative hybridization of arrayed cDNA clones. Genomics (1995) 2.09
Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development. Proc Natl Acad Sci U S A (1996) 1.55
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur J Immunol (2000) 1.55
Academic record and subsequent career. Proc R Soc Med (1967) 1.52
Visceral artery aneurysms. Ann Vasc Surg (2005) 1.44
Social medicine and its contribution to social policy. Lancet (1978) 1.43
A course in psychology and sociology for medical students. Lancet (1967) 1.42
Safe and cost-effective approach to carotid surgery. Eur J Vasc Endovasc Surg (1997) 1.40
Metabolism in vitro of (4- 14 C)4-androstene-3,17-dione by livers from normal and carbon tetrachloride-poisoned rats. Biochem J (1971) 1.39
Mechanism of action of the novel aminomethylcycline antibiotic omadacycline. Antimicrob Agents Chemother (2013) 1.39
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs. Br J Pharmacol (1989) 1.35
Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice. FEBS Lett (2000) 1.32
Infections with FK 506 immunosuppression: preliminary results with primary therapy. Transplant Proc (1990) 1.30
The global atmospheric environment for the next generation. Environ Sci Technol (2006) 1.30
Facilitated detection of antibiotic-resistant Pseudomonas in cystic fibrosis sputum using homogenized specimens and antibiotic-containing media. Diagn Microbiol Infect Dis (1986) 1.29
Bacteriology of sputum in cystic fibrosis: evaluation of dithiothreitol as a mucolytic agent. J Clin Microbiol (1980) 1.24
Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice. Br J Cancer (1976) 1.23
Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. J Exp Med (1991) 1.19
A radiologic index of pulmonary arterial hypertension. Chest (1975) 1.19
Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues. Cytogenet Cell Genet (1994) 1.17
Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene. Mol Cell Biol (1996) 1.17
Localization of the mcf.2 transforming sequence to the X chromosome. EMBO J (1987) 1.16
Catheter infection caused by Methylobacterium in immunocompromised hosts: report of three cases and review of the literature. Clin Infect Dis (1992) 1.16
Liver abscess. The need for complete gastrointestinal evaluation. Arch Surg (1989) 1.16
Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. Immunogenetics (2001) 1.15
Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer. Oncogene (2006) 1.15
Vascular prosthetic graft infection: epidemiology, bacteriology, pathogenesis and treatment. Acta Chir Belg (2002) 1.13
The copper catalyzed oxidation of cysteine to cystine. Arch Biochem Biophys (1969) 1.13
Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression. J Immunol (1996) 1.11
Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing. Immunity (1996) 1.11
Permanent expression of p53 in FR 3T3 rat cells but cell cycle-dependent association with large-T antigen in simian virus 40 transformants. EMBO J (1985) 1.10
In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells. EMBO J (1995) 1.10
A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol Immunol (1998) 1.09
Altered lymphoid development in mice deficient for the mAF4 proto-oncogene. Blood (2000) 1.09
LDL oxidation in patients with severe carotid atherosclerosis. A study of in vitro and in vivo oxidation markers. Arterioscler Thromb (1994) 1.07
The neurotoxic effect of cuprizone on oligodendrocytes depends on the presence of pro-inflammatory cytokines secreted by microglia. Neurochem Res (2006) 1.07
Is pantetheinase the actual identity of mouse and human vanin-1 proteins? FEBS Lett (1999) 1.06
Efficacy and safety of a low-molecular-weight heparin and standard unfractionated heparin for prophylaxis of postoperative venous thromboembolism: European multicenter trial. World J Surg (1997) 1.06
cDNA cloning for mouse thymocyte-activating molecule. A multifunctional ecto-dipeptidyl peptidase IV (CD26) included in a subgroup of serine proteases. J Biol Chem (1992) 1.05
The enzymatic breakdown of pantethine to pantothenic acid and cystamine. Eur J Biochem (1970) 1.02
Structure, chromosome mapping and expression of the murine Fgf-6 gene. Oncogene (1990) 1.02
Sulfur-containing cyclic ketimines and imino acids. A novel family of endogenous products in the search for a role. Eur J Biochem (1991) 1.01
Activation of primary human T-lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-kappa B. Cell Growth Differ (1993) 1.01
Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1. Leukemia (2011) 1.00
Differential gene expression in CD3epsilon- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation. Immunogenetics (1999) 1.00
Natural killer cells and malignant haemopathies: a model for the interaction of cancer with innate immunity. Cancer Immunol Immunother (2010) 0.99
Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function. Cell Death Differ (2011) 0.99
Loss of AF6/afadin, a marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth. Oncogene (2011) 0.98
Dientamoeba fragilis, a protozoan parasite in adult members of a semicommunal group. Dig Dis Sci (1983) 0.98
A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers. Clin Pharmacol Ther (1995) 0.97
I-A alpha polymorphic residues that determine alloreactive T cell recognition. J Exp Med (1989) 0.96
Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation. J Biol Chem (1997) 0.95
Bleeding stomal varices. The role of local treatment. Dis Colon Rectum (1990) 0.95
Expression of the tumor necrosis factor locus is not necessary for the cytolytic activity of T lymphocytes. J Immunol (1988) 0.95
Mouse thymic epithelial cell lines interact with and select a CD3lowCD4+CD8+ thymocyte subset through an LFA-1-dependent adhesion--de-adhesion mechanism. Int Immunol (1990) 0.94
Dissection of the Poly(Glu60Ala30Tyr10) (GAT)-specific T-cell repertoire in H-2Ik mice. II. The use of monoclonal antibodies to study the recognition of Ia antigens by GAT-reactive T-cell clones. Immunogenetics (1983) 0.94
Evidence that murine hematopoietic cell subset marker J11d is attached to a glycosyl-phosphatidylinositol membrane anchor. Eur J Immunol (1987) 0.94
TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex. EMBO J (2000) 0.94
IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells. Oncogene (2000) 0.93
Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV). J Immunol (1991) 0.93
Economic evaluation of immunoglobulin replacement in patients with primary antibody deficiencies. Clin Exp Immunol (2009) 0.92
Insulin stimulates haptotactic migration of human epidermal keratinocytes through activation of NF-kappa B transcription factor. J Cell Sci (1997) 0.91
Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105. Oncogene (1999) 0.91
Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus. Mol Cell Biol (2001) 0.90
An ESTs description of the new Vanin gene family conserved from fly to human. Immunogenetics (1999) 0.89
Analysis of the Thy-1 pathway of T cell hybridoma activation using 17 rat monoclonal antibodies reactive with distinct Thy-1 epitopes. Eur J Immunol (1985) 0.88
Thymocytes and RelB-dependent medullary epithelial cells provide growth-promoting and organization signals, respectively, to thymic medullary stromal cells. Eur J Immunol (1997) 0.88
Structural characteristics of the mouse transferrin receptor. Eur J Biochem (1984) 0.88
Identification of 5 topographic domains of the mouse LFA-1 molecule: subunit assignment and functional involvement in lymphoid cell interactions. J Immunol (1986) 0.88
Stüve-Wiedemann syndrome and defects of the mitochondrial respiratory chain. Am J Med Genet (1997) 0.88
Efficiency of antigen presentation to T cell clones by (B cell X B cell lymphoma) hybridomas correlates quantitatively with cell surface ia antigen expression. Eur J Immunol (1984) 0.87
NPY receptor subtypes involved in the contraction of the proximal colon of the rat. Regul Pept (1998) 0.87
Potentiating effects of oxygen in lungs damaged by methylcyclopentadienyl manganese tricarbonyl, cadmium chloride, oleic acid, and antitumor drugs. Toxicol Appl Pharmacol (1983) 0.87
Dissection of the poly(glu60 ala30 tyr10) (GAT)-specific T-cell repertoire in H-2Ik mice. I. GAT plus self-I-Ak-reactive T-cell clones can recognize alloactivating and/or restriction determinants on nonself-Ia molecules. Immunogenetics (1983) 0.87
The human basic fibroblast growth factor gene is located on the long arm of chromosome 4 at bands q26-q27. Oncogene Res (1990) 0.87
Enzymatically labelled nucleic acid (NA) probe assays for detection of Campylobacter spp. in human faecal specimens and in culture. Mol Cell Probes (1990) 0.87
Apoptosis of Caco-2 intestinal cells invaded by Listeria monocytogenes: protective effect of lactoferrin. Exp Cell Res (1999) 0.87
Isolation and characterization of a novel glycosyl-phosphatidylinositol-anchored glycoconjugate expressed by developing neurons. Eur J Biochem (1992) 0.86
[Comparative double-blind study of bromazepam versus prazepam in non-psychotic anxiety]. Encephale (1994) 0.86
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor. Proc Natl Acad Sci U S A (1997) 0.86
Simian virus 40 T antigen is detected only in cells in the G2 phase of the cell cycle in one group of rat transformants. Virology (1983) 0.86
Susceptibilities to rimantadine of influenza A/H1N1 and A/H3N2 viruses isolated during the epidemics of 1988 to 1989 and 1989 to 1990. Antimicrob Agents Chemother (1993) 0.86
Rapid detection of group A streptococci: comparative performance by nurses and laboratory technologists in pediatric satellite laboratories using three test kits. J Clin Microbiol (1992) 0.86
Activation of a mcf.2 oncogene by deletion of amino-terminal coding sequences. Oncogene (1988) 0.86
Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients. J Immunol (2000) 0.85