Published in FASEB J on August 02, 2004
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev (2008) 2.98
Minireview: Defining the roles of the iodothyronine deiodinases: current concepts and challenges. Endocrinology (2009) 1.40
Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion. J Clin Invest (2010) 1.28
Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases. Endocrinology (2009) 1.26
Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands. J Biol Chem (2009) 1.05
Recent insights into the cell biology of thyroid angiofollicular units. Endocr Rev (2013) 0.93
Efficient use and recycling of the micronutrient iodide in mammals. Biochimie (2010) 0.91
The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia. BMC Genomics (2007) 0.87
Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus. Protein Sci (2012) 0.84
Rapid kinetics of dehalogenation promoted by iodotyrosine deiodinase from human thyroid. Biochemistry (2015) 0.84
A switch between one- and two-electron chemistry of the human flavoprotein iodotyrosine deiodinase is controlled by substrate. J Biol Chem (2014) 0.83
Liver X receptor β controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue. Proc Natl Acad Sci U S A (2015) 0.80
The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. PLoS Genet (2014) 0.77
The metabolism and de-bromination of bromotyrosine in vivo. Free Radic Biol Med (2015) 0.77
The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in Caenorhabditis elegans. G3 (Bethesda) (2014) 0.76
Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin. Thyroid (2016) 0.75
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med (2006) 2.61
Dual oxidase2 is expressed all along the digestive tract. Am J Physiol Gastrointest Liver Physiol (2004) 1.84
Ultrasound criteria of malignancy for cervical lymph nodes in patients followed up for differentiated thyroid cancer. J Clin Endocrinol Metab (2007) 1.72
Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid Redox Signal (2009) 1.71
Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity. J Biol Chem (2005) 1.67
Prognostic factors for persistent or recurrent disease of papillary thyroid carcinoma with neck lymph node metastases and/or tumor extension beyond the thyroid capsule at initial diagnosis. J Clin Endocrinol Metab (2005) 1.64
Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma. PLoS One (2011) 1.39
The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells. J Immunol (2008) 1.35
Prognostic parameters of metastatic adrenocortical carcinoma. J Clin Endocrinol Metab (2006) 1.30
Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues. Endocr Relat Cancer (2010) 1.20
Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer. J Clin Endocrinol Metab (2003) 1.17
Combined treatment of anaplastic thyroid carcinoma with surgery, chemotherapy, and hyperfractionated accelerated external radiotherapy. Int J Radiat Oncol Biol Phys (2004) 1.15
Relationship between tumor burden and serum thyroglobulin level in patients with papillary and follicular thyroid carcinoma. Thyroid (2002) 1.13
Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes. J Clin Endocrinol Metab (2002) 1.11
Cisplatin resistance associated with PARP hyperactivation. Cancer Res (2013) 1.11
Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia. Blood (2003) 1.10
Follicular thyroid tumors with the PAX8-PPARgamma1 rearrangement display characteristic genetic alterations. Am J Pathol (2005) 1.09
MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes. J Mol Neurosci (2004) 1.06
The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling. Sci Signal (2010) 1.06
Cloning of S-adenosyl-L-methionine:C-24-Delta-sterol-methyltransferase (ERG6) from Leishmania donovani and characterization of mRNAs in wild-type and amphotericin B-Resistant promastigotes. Antimicrob Agents Chemother (2004) 1.04
New insight into the Nox4 subcellular localization in HEK293 cells: first monoclonal antibodies against Nox4. Biochimie (2010) 1.02
Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease. Scand J Gastroenterol (2007) 0.98
Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models. Clin Cancer Res (2011) 0.98
Poorly differentiated follicular thyroid carcinoma: prognostic factors and relevance of histological classification. Thyroid (2007) 0.97
Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells. Cancer Res (2010) 0.96
Targeting of the dual oxidase 2 N-terminal region to the plasma membrane. J Biol Chem (2004) 0.96
The emerging role of ROS-generating NADPH oxidase NOX4 in DNA-damage responses. Mutat Res (2012) 0.94
PAX8 and peroxisome proliferator-activated receptor gamma 1 gene expression status in benign and malignant thyroid tissues. Eur J Endocrinol (2004) 0.92
NADPH Oxidases NOXs and DUOXs as putative targets for cancer therapy. Anticancer Agents Med Chem (2013) 0.92
Functional consequences of dual oxidase-thyroperoxidase interaction at the plasma membrane. J Clin Endocrinol Metab (2010) 0.91
Is (18)F-fluorodeoxyglucose-PET/CT useful for the presurgical characterization of thyroid nodules with indeterminate fine needle aspiration cytology? Thyroid (2012) 0.91
Oxidative stress regulates type 3 deiodinase and type 2 deiodinase in cultured rat astrocytes. Endocrinology (2008) 0.88
Expression of cell cycle biomarkers and telomere length in papillary thyroid carcinoma: a comparative study between radiation-associated and spontaneous cancers. Am J Clin Oncol (2009) 0.88
Expression of the apical iodide transporter in human thyroid tissues: a comparison study with other iodide transporters. J Clin Endocrinol Metab (2004) 0.88
Gene expression signature discriminates sporadic from post-radiotherapy-induced thyroid tumors. Endocr Relat Cancer (2011) 0.87
Implication of type 3 deiodinase induction in zebrafish fin regeneration. Gen Comp Endocrinol (2010) 0.86
Age-dependent variation of follicular size and expression of iodine transporters in human thyroid tissue. J Nucl Med (2004) 0.85
Wnt and lithium: a common destiny in the therapy of nervous system pathologies? Cell Mol Life Sci (2013) 0.85
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells. PLoS One (2011) 0.84
Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles. Endocrinology (2003) 0.84
Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation. Fundam Clin Pharmacol (2012) 0.83
Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways. Endocr Relat Cancer (2009) 0.83
Familial medullary thyroid carcinoma: clinical variability and low aggressiveness associated with RET mutation at codon 804. J Clin Endocrinol Metab (2002) 0.83
Bacterial lipopolysaccharide induces type 2 deiodinase in cultured rat astrocytes. J Endocrinol (2010) 0.82
Sodium/iodide symporter (NIS) gene expression is the limiting step for the onset of thyroid function in the human fetus. J Clin Endocrinol Metab (2006) 0.82
Sexual dimorphism of thyroid reactive oxygen species production due to higher NADPH oxidase 4 expression in female thyroid glands. Thyroid (2013) 0.81
Functional characterization of human thyroid tissue with immunohistochemistry. Thyroid (2007) 0.81
Mutational status of EGFR, BRAF, PI3KCA and JAK2 genes in endocrine tumors. Int J Cancer (2009) 0.81
Differential expression of galectin-3 in medullary thyroid carcinoma and C-cell hyperplasia. Clin Endocrinol (Oxf) (2002) 0.81
HEX, PAX-8 and TTF-1 gene expression in human thyroid tissues: a comparative analysis with other genes involved in iodide metabolism. Clin Endocrinol (Oxf) (2006) 0.81
Medullary thyroid carcinoma arises in the absence of prolactin signaling. Cancer Res (2005) 0.80
Neck recurrence from thyroid carcinoma: serum thyroglobulin and high-dose total body scan are not reliable criteria for cure after radioiodine treatment. Clin Endocrinol (Oxf) (2005) 0.80
Sexual dimorphism and thyroid dysfunction: a matter of oxidative stress? J Endocrinol (2014) 0.80
Characteristics of follicular cell-derived thyroid carcinomas occurring after external radiation exposure: results of a case control study nested in a cohort. Thyroid (2002) 0.80
Changes in signaling pathways induced by vandetanib in a human medullary thyroid carcinoma model, as analyzed by reverse phase protein array. Thyroid (2013) 0.80