Published in Antioxid Redox Signal on October 01, 2009
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov (2011) 3.08
Nitric oxide and redox mechanisms in the immune response. J Leukoc Biol (2011) 1.97
Linking mitochondrial bioenergetics to insulin resistance via redox biology. Trends Endocrinol Metab (2012) 1.64
Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer (2012) 1.57
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56
The type I NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-alpha-mediated host cell apoptosis. PLoS Pathog (2010) 1.44
Redox control of inflammation in macrophages. Antioxid Redox Signal (2013) 1.39
The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology (2011) 1.33
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. Free Radic Biol Med (2011) 1.31
NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats. Antioxid Redox Signal (2010) 1.30
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci U S A (2011) 1.28
Angiotensin II, NADPH oxidase, and redox signaling in the vasculature. Antioxid Redox Signal (2012) 1.27
Targeting NADPH oxidases in vascular pharmacology. Vascul Pharmacol (2012) 1.20
Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research. Antioxid Redox Signal (2013) 1.14
Redox metabolism and malignancy. Curr Opin Pharmacol (2010) 1.10
The role of reactive-oxygen-species in microbial persistence and inflammation. Int J Mol Sci (2011) 1.08
Molecular mechanisms underlying chronic inflammation-associated cancers. Cancer Lett (2013) 1.06
New insights on NOX enzymes in the central nervous system. Antioxid Redox Signal (2014) 1.06
Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation. Antioxid Redox Signal (2010) 1.05
Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress. Cell Health Cytoskelet (2012) 1.04
Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy. J Mol Cell Biol (2011) 1.03
Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex. Proc Natl Acad Sci U S A (2013) 1.02
Selenium, selenoproteins and the thyroid gland: interactions in health and disease. Nat Rev Endocrinol (2011) 1.01
Rhinovirus-induced barrier dysfunction in polarized airway epithelial cells is mediated by NADPH oxidase 1. J Virol (2011) 1.00
Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury. J Neuroinflammation (2013) 0.99
Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. Free Radic Res (2010) 0.99
NADPH oxidases: a perspective on reactive oxygen species production in tumor biology. Antioxid Redox Signal (2013) 0.99
Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. Free Radic Biol Med (2013) 0.99
Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidases. Biochim Biophys Acta (2013) 0.97
The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls. Antioxid Redox Signal (2013) 0.96
Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide. Free Radic Biol Med (2012) 0.95
NADPH oxidase as a therapeutic target for oxalate induced injury in kidneys. Oxid Med Cell Longev (2013) 0.95
Are reactive oxygen species always detrimental to pathogens? Antioxid Redox Signal (2013) 0.95
Oxidative damage to macromolecules in the thyroid - experimental evidence. Thyroid Res (2012) 0.95
Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme. J Clin Biochem Nutr (2011) 0.94
Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4. Am J Physiol Cell Physiol (2012) 0.93
Oxidative stress and adult neurogenesis--effects of radiation and superoxide dismutase deficiency. Semin Cell Dev Biol (2012) 0.92
Tetraspanin is required for generation of reactive oxygen species by the dual oxidase system in Caenorhabditis elegans. PLoS Genet (2012) 0.89
Rho GTPases, oxidation, and cell redox control. Small GTPases (2014) 0.87
Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages. Mol Pharmacol (2012) 0.86
Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. Free Radic Biol Med (2013) 0.85
New insights into the roles of NADPH oxidases in sexual development and ascospore germination in Sordaria macrospora. Genetics (2014) 0.85
Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons. Am J Physiol Regul Integr Comp Physiol (2013) 0.85
Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins. J Biol Chem (2013) 0.85
Current status of NADPH oxidase research in cardiovascular pharmacology. Vasc Health Risk Manag (2013) 0.85
Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ßI and prooxidant enzyme NADPH oxidase. Redox Biol (2014) 0.85
HIF-1α activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase. PLoS One (2015) 0.84
Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation. J Biol Chem (2016) 0.83
Redox regulation of Rac1 by thiol oxidation. Free Radic Biol Med (2014) 0.83
The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation. Redox Biol (2014) 0.83
Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice. Mol Cells (2013) 0.82
Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation. J Biol Chem (2014) 0.82
The involvement of NADPH oxidase-mediated ROS in cytokine secretion from macrophages induced by Mycobacterium tuberculosis ESAT-6. Inflammation (2014) 0.81
A pathway linking oxidative stress and the Ran GTPase system in progeria. Mol Biol Cell (2014) 0.81
High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases. J Biol Chem (2014) 0.81
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Sci Rep (2016) 0.81
MicroRNA-125b regulates microglia activation and motor neuron death in ALS. Cell Death Differ (2016) 0.80
Role of the NADPH Oxidases DUOX and NOX4 in Thyroid Oxidative Stress. Eur Thyroid J (2013) 0.80
The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release. J Biol Chem (2015) 0.79
Pharmacology and Clinical Drug Candidates in Redox Medicine. Antioxid Redox Signal (2015) 0.79
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications. Antioxid Redox Signal (2015) 0.79
Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease. J Am Soc Nephrol (2015) 0.79
The basic chemistry of exercise-induced DNA oxidation: oxidative damage, redox signaling, and their interplay. Front Physiol (2015) 0.78
The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production. J Biol Chem (2014) 0.78
NADPH oxidase in brain injury and neurodegenerative disorders. Mol Neurodegener (2017) 0.78
DUOX2 Expression Is Increased in Barrett Esophagus and Cancerous Tissues of Stomach and Colon. Gastroenterol Res Pract (2015) 0.77
Mechanistic link between erectile dysfunction and systemic endothelial dysfunction in type 2 diabetic rats. Andrology (2016) 0.77
Estimating genetic effect sizes under joint disease-endophenotype models in presence of gene-environment interactions. Front Genet (2015) 0.77
NADPH oxidase (NOX2) activity is a modifier of survival in ALS. J Neurol (2014) 0.76
Co-occurrence of tetraspanin and ROS generators: Conservation in protein cross-linking and other developmental processes. Worm (2013) 0.76
Increased expression of NAPDH oxidase 4 in systemic sclerosis dermal fibroblasts: regulation by transforming growth factor β. Arthritis Rheumatol (2015) 0.76
A Critical Review of Methodologies to Detect Reactive Oxygen and Nitrogen Species Stimulated by NADPH Oxidase Enzymes: Implications in Pesticide Toxicity. Curr Pharmacol Rep (2016) 0.76
Diminished COX-2/PGE2-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells. PLoS One (2016) 0.75
Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss. BMC Musculoskelet Disord (2016) 0.75
Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide. J Neuroinflammation (2017) 0.75
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury. J Biol Chem (2016) 0.75
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC. Redox Biol (2017) 0.75
Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases. Cell Biochem Biophys (2017) 0.75
The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. PLoS Genet (2017) 0.75
Regulation of platelet activation and thrombus formation by reactive oxygen species. Redox Biol (2017) 0.75
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis (1997) 57.27
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J (2000) 7.48
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. J Cell Biol (1983) 5.73
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature (1991) 5.16
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal (2005) 4.74
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K. Nat Cell Biol (2001) 4.64
Identification of renox, an NAD(P)H oxidase in kidney. Proc Natl Acad Sci U S A (2000) 4.24
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J (2007) 3.88
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J Cell Biol (2001) 3.63
Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med (2007) 3.44
Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. FASEB J (2003) 3.44
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. J Biol Chem (2004) 3.37
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation (2005) 3.12
Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS J (2008) 3.04
Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation (2005) 2.79
Assembly of the phagocyte NADPH oxidase. Histochem Cell Biol (2004) 2.71
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J Biol Chem (2000) 2.70
A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med (2006) 2.61
The Nox family of NAD(P)H oxidases: host defense and beyond. J Biol Chem (2004) 2.48
Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein. Nature (1985) 2.46
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J Biol Chem (2002) 2.41
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat Cell Biol (2001) 2.39
The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems. Biochim Biophys Acta (2004) 2.39
The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells. Genes Cells (2005) 2.38
Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas. J Biol Chem (1999) 2.37
Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation. Biochemistry (2002) 2.31
Molecular basis of phosphorylation-induced activation of the NADPH oxidase. Cell (2003) 2.31
Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes. BMC Evol Biol (2007) 2.29
Regulated hydrogen peroxide production by Duox in human airway epithelial cells. Am J Respir Cell Mol Biol (2005) 2.25
Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase. Proc Natl Acad Sci U S A (1994) 2.25
Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal (2009) 2.17
Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases. J Biol Chem (2003) 2.12
Decreased blood pressure in NOX1-deficient mice. FEBS Lett (2005) 2.10
Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction. EMBO J (2002) 2.09
Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent. J Biol Chem (2006) 2.08
Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. N Engl J Med (2002) 2.07
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med (2006) 2.03
Nox1-dependent reactive oxygen generation is regulated by Rac1. J Biol Chem (2006) 2.02
Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing. J Exp Med (2006) 2.01
Absence of both cytochrome b-245 subunits from neutrophils in X-linked chronic granulomatous disease. Nature (1987) 1.98
Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets. Proc Natl Acad Sci U S A (1994) 1.92
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5). J Biol Chem (2004) 1.86
Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation. J Biol Chem (2005) 1.85
Dual oxidase2 is expressed all along the digestive tract. Am J Physiol Gastrointest Liver Physiol (2004) 1.84
Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. Mol Cell Biol (2004) 1.82
Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases. Mol Cell Biol (2006) 1.80
Subcellular localization and function of alternatively spliced Noxo1 isoforms. Free Radic Biol Med (2006) 1.76
Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558. J Biol Chem (1994) 1.74
Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells. J Biol Chem (2003) 1.70
NOX family NADPH oxidases: not just in mammals. Biochimie (2007) 1.68
Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events. J Biol Chem (1990) 1.68
Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity. J Biol Chem (2005) 1.67
Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1. J Biol Chem (2006) 1.66
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase. Genes Dev (2004) 1.64
NADPH oxidase-dependent acid production in airway epithelial cells. J Biol Chem (2004) 1.63
NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain. J Biol Chem (2003) 1.56
Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration. J Biol Chem (2006) 1.52
Identification of structural elements in Nox1 and Nox4 controlling localization and activity. Antioxid Redox Signal (2009) 1.51
Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice. J Clin Invest (2008) 1.49
The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators. J Biol Chem (2005) 1.48
Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease. Blood (1989) 1.47
Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism. J Clin Endocrinol Metab (2007) 1.41
Dual oxidases. Philos Trans R Soc Lond B Biol Sci (2005) 1.37
Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox. J Biol Chem (2002) 1.36
Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB J (2008) 1.36
The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells. J Immunol (2008) 1.35
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. J Biol Chem (2008) 1.34
Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. J Biol Chem (2006) 1.33
Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system. Exp Cell Res (2002) 1.32
The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction. Clin Sci (Lond) (2006) 1.31
The oxidative burst at fertilization is dependent upon activation of the dual oxidase Udx1. Dev Cell (2004) 1.29
Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells. Am J Physiol Cell Physiol (2004) 1.28
Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding. J Biol Chem (2007) 1.28
Inactivation of NADPH oxidase organizer 1 results in severe imbalance. Curr Biol (2006) 1.27
PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation. EMBO J (2006) 1.22
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2. Mol Endocrinol (2007) 1.21
Evidence for a superoxide permeability pathway in endosomal membranes. Mol Cell Biol (2008) 1.21
Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity. J Biol Chem (2006) 1.19
A phosphoprotein of Mr 47,000, defective in autosomal chronic granulomatous disease, copurifies with one of two soluble components required for NADPH:O2 oxidoreductase activity in human neutrophils. J Clin Invest (1989) 1.14
A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox. Mol Biol Cell (2006) 1.14
Sequential binding of cytosolic Phox complex to phagosomes through regulated adaptor proteins: evaluation using the novel monomeric Kusabira-Green System and live imaging of phagocytosis. J Immunol (2008) 1.10
Phosphatidylinositol 3-phosphate-dependent and -independent functions of p40phox in activation of the neutrophil NADPH oxidase. J Biol Chem (2007) 1.09
Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism. J Biol Chem (2008) 1.08
Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues. J Clin Endocrinol Metab (2001) 1.06
Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3. Gene (2005) 1.05
Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region. Mol Biol Cell (2008) 1.05
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase. J Biol Chem (2007) 1.01
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. J Clin Invest (2003) 1.01
Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1. Mol Biol Cell (2005) 0.99
Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome. J Immunol (2005) 0.97
Superoxide production at phagosomal cup/phagosome through beta I protein kinase C during Fc gamma R-mediated phagocytosis in microglia. J Immunol (2004) 0.97
Targeting of the dual oxidase 2 N-terminal region to the plasma membrane. J Biol Chem (2004) 0.96
Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding. EMBO J (2007) 0.96
NADPH-dependent H2O2 generation catalyzed by thyroid plasma membranes. Studies with electron scavengers. Eur J Biochem (1989) 0.93
NADPH-dependent generation of H2O2 in a thyroid particulate fraction requires Ca2+. FEBS Lett (1985) 0.91
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic Biol Med (2008) 0.91
Dual oxidase2 is expressed all along the digestive tract. Am J Physiol Gastrointest Liver Physiol (2004) 1.84
Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity. J Biol Chem (2005) 1.67
Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB J (2008) 1.36
A role for PKC-epsilon in Fc gammaR-mediated phagocytosis by RAW 264.7 cells. J Cell Biol (2002) 1.12
Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia. Blood (2003) 1.10
Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel. J Biol Chem (2010) 1.09
Enzymological analysis of mutant protein kinase Cgamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis. J Biol Chem (2008) 1.06
The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling. Sci Signal (2010) 1.06
Cloning of S-adenosyl-L-methionine:C-24-Delta-sterol-methyltransferase (ERG6) from Leishmania donovani and characterization of mRNAs in wild-type and amphotericin B-Resistant promastigotes. Antimicrob Agents Chemother (2004) 1.04
Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site. FASEB J (2004) 1.00
Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha. Biochem J (2008) 1.00
Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1. Mol Biol Cell (2005) 0.99
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell (2013) 0.99
Involvement of gamma protein kinase C in estrogen-induced neuroprotection against focal brain ischemia through G protein-coupled estrogen receptor. J Neurochem (2005) 0.90
Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase. J Biol Chem (2004) 0.90
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. J Biol Chem (2013) 0.86
Nuclear transportation of diacylglycerol kinase gamma and its possible function in the nucleus. J Biol Chem (2005) 0.83
Subtype- and species-specific knockdown of PKC using short interfering RNA. Biochem Biophys Res Commun (2002) 0.83
Comparison of common homology modeling algorithms: application of user-defined alignments. Methods Mol Biol (2012) 0.81
Cloning and characterization of a novel isoform of iodotyrosine dehalogenase 1 (DEHAL1) DEHAL1C from human thyroid: comparisons with DEHAL1 and DEHAL1B. Thyroid (2006) 0.79
Ca2+ oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (gammaPKC). Neurosci Lett (2008) 0.77
A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy. Pflugers Arch (2009) 0.77
Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocyte differentiation. Mol Biol Cell (2011) 0.76
In vivo transgene expression using an adenoviral tetracycline-regulated system with neuron-specific enolase promoter. Biochem Biophys Res Commun (2004) 0.76
Enhanced generation of reactive oxygen species by interferon-γ may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease. Int J Hematol (2013) 0.76
Novel variants of murine serotonin transporter mRNA and the promoter activity of its upstream site. Neurosci Lett (2003) 0.75
Evolutionary epidemiology of Neisseria meningitidis strains in Belarus compared to other European countries. Acta Microbiol Immunol Hung (2013) 0.75