Published in Microbiology on August 01, 2004
Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev (2005) 14.71
Life on the inside: the intracellular lifestyle of cytosolic bacteria. Nat Rev Microbiol (2009) 2.62
Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence. Infect Immun (2006) 2.24
IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri. Infect Immun (2006) 2.24
A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens. Proc Natl Acad Sci U S A (2009) 2.10
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J Biol Chem (2006) 1.72
Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. Infect Immun (2006) 1.54
Burkholderia thailandensis as a model system for the study of the virulence-associated type III secretion system of Burkholderia pseudomallei. Infect Immun (2008) 1.52
The Burkholderia pseudomallei type III secretion system and BopA are required for evasion of LC3-associated phagocytosis. PLoS One (2011) 1.38
Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB. J Bacteriol (2005) 1.38
Strategies for Intracellular Survival of Burkholderia pseudomallei. Front Microbiol (2011) 1.35
A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proc Natl Acad Sci U S A (2009) 1.29
Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes. PLoS Negl Trop Dis (2012) 1.28
A Burkholderia pseudomallei deltapurM mutant is avirulent in immunocompetent and immunodeficient animals: candidate strain for exclusion from select-agent lists. Infect Immun (2010) 1.26
Identification of tomato plant as a novel host model for Burkholderia pseudomallei. BMC Microbiol (2010) 1.12
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Proc Natl Acad Sci U S A (2005) 1.11
Development of vaccines against burkholderia pseudomallei. Front Microbiol (2011) 1.10
Conformational stability and differential structural analysis of LcrV, PcrV, BipD, and SipD from type III secretion systems. Protein Sci (2007) 1.10
Strategies toward vaccines against Burkholderia mallei and Burkholderia pseudomallei. Expert Rev Vaccines (2008) 1.09
Development of Burkholderia mallei and pseudomallei vaccines. Front Cell Infect Microbiol (2013) 1.08
Immunospecific responses to bacterial elongation factor Tu during Burkholderia infection and immunization. PLoS One (2010) 1.08
Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors. Infect Immun (2010) 1.07
Protection against heterologous Burkholderia pseudomallei strains by dendritic cell immunization. Infect Immun (2006) 1.07
Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region. Infect Immun (2012) 1.07
Genetic and transcriptional analysis of the siderophore malleobactin biosynthesis and transport genes in the human pathogen Burkholderia pseudomallei K96243. J Bacteriol (2006) 1.06
CdpA is a Burkholderia pseudomallei cyclic di-GMP phosphodiesterase involved in autoaggregation, flagellum synthesis, motility, biofilm formation, cell invasion, and cytotoxicity. Infect Immun (2010) 1.04
Bioluminescent diagnostic imaging to characterize altered respiratory tract colonization by the burkholderia pseudomallei capsule mutant. Front Microbiol (2011) 1.04
Neutrophil extracellular traps exhibit antibacterial activity against burkholderia pseudomallei and are influenced by bacterial and host factors. Infect Immun (2012) 1.04
Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei. Front Microbiol (2011) 1.02
NMR characterization of the interaction of the Salmonella type III secretion system protein SipD and bile salts. Biochemistry (2010) 1.01
The animal pathogen-like type III secretion system is required for the intracellular survival of Burkholderia mallei within J774.2 macrophages. Infect Immun (2006) 1.00
Role for the Burkholderia pseudomallei capsular polysaccharide encoded by the wcb operon in acute disseminated melioidosis. Infect Immun (2009) 0.99
Dictyostelium discoideum as a model system for identification of Burkholderia pseudomallei virulence factors. Infect Immun (2011) 0.98
Expression, purification, crystallization and preliminary crystallographic analysis of BipD, a component of the Burkholderia pseudomallei type III secretion system. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.98
The condition-dependent transcriptional landscape of Burkholderia pseudomallei. PLoS Genet (2013) 0.96
Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells. BMC Microbiol (2010) 0.95
Burkholderia mallei cellular interactions in a respiratory cell model. J Med Microbiol (2009) 0.95
Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. BMC Microbiol (2010) 0.94
T346Hunter: a novel web-based tool for the prediction of type III, type IV and type VI secretion systems in bacterial genomes. PLoS One (2015) 0.94
Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243. PLoS One (2010) 0.94
Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders. Front Cell Infect Microbiol (2012) 0.93
Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages. PLoS Pathog (2014) 0.91
The Rho GTPase inactivation domain in Vibrio cholerae MARTX toxin has a circularly permuted papain-like thiol protease fold. Proteins (2009) 0.90
Burkholderia vaccines: are we moving forward? Front Cell Infect Microbiol (2013) 0.90
Protection against experimental melioidosis following immunization with live Burkholderia thailandensis expressing a manno-heptose capsule. Clin Vaccine Immunol (2013) 0.90
Insights into cross-kingdom plant pathogenic bacteria. Genes (Basel) (2011) 0.89
Burkholderia pseudomallei proteins presented by monocyte-derived dendritic cells stimulate human memory T cells in vitro. Infect Immun (2010) 0.88
Correlates of immune protection following cutaneous immunization with an attenuated Burkholderia pseudomallei vaccine. Infect Immun (2013) 0.86
Caspase-1 activation via Rho GTPases: a common theme in mucosal infections? PLoS Pathog (2010) 0.85
Melioidosis: molecular aspects of pathogenesis. Expert Rev Anti Infect Ther (2014) 0.85
Type 3 secretion system cluster 3 is a critical virulence determinant for lung-specific melioidosis. PLoS Negl Trop Dis (2015) 0.85
A Burkholderia pseudomallei outer membrane vesicle vaccine provides protection against lethal sepsis. Clin Vaccine Immunol (2014) 0.85
Capsule influences the deposition of critical complement C3 levels required for the killing of Burkholderia pseudomallei via NADPH-oxidase induction by human neutrophils. PLoS One (2012) 0.84
Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms. PLoS Comput Biol (2015) 0.84
The Madagascar hissing cockroach as a novel surrogate host for Burkholderia pseudomallei, B. mallei and B. thailandensis. BMC Microbiol (2012) 0.83
Characterization of BcaA, a putative classical autotransporter protein in Burkholderia pseudomallei. Infect Immun (2013) 0.82
Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon. BMC Microbiol (2014) 0.81
Structural insights into WcbI, a novel polysaccharide-biosynthesis enzyme. IUCrJ (2013) 0.81
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Mol Cell Proteomics (2015) 0.79
Crystallization and preliminary X-ray diffraction analysis of BipD, a virulence factor from Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.79
Cationic liposomes extend the immunostimulatory effect of CpG oligodeoxynucleotide against Burkholderia pseudomallei infection in BALB/c mice. Clin Vaccine Immunol (2012) 0.79
Analysis of the prevalence, secretion and function of a cell cycle-inhibiting factor in the melioidosis pathogen Burkholderia pseudomallei. PLoS One (2014) 0.78
The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis. J Bacteriol (2013) 0.78
Genomic characterization of Burkholderia pseudomallei isolates selected for medical countermeasures testing: comparative genomics associated with differential virulence. PLoS One (2015) 0.78
Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. BMC Microbiol (2014) 0.77
Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. PLoS One (2015) 0.77
Melioidosis: Clinical impact and public health threat in the tropics. PLoS Negl Trop Dis (2017) 0.76
Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Burkholderia pseudomallei type III secretion system cluster 3 ATPase BsaS, a chemotherapeutic target for small-molecule ATPase inhibitors. Infect Immun (2015) 0.76
The Burkholderia pseudomallei Proteins BapA and BapC Are Secreted TTSS3 Effectors and BapB Levels Modulate Expression of BopE. PLoS One (2015) 0.75
Rapid and Sensitive Multiplex Detection of Burkholderia pseudomallei-Specific Antibodies in Melioidosis Patients Based on a Protein Microarray Approach. PLoS Negl Trop Dis (2016) 0.75
Involvement of L-selectin expression in Burkholderia pseudomallei-infected monocytes invading the brain during murine melioidosis. Virulence (2016) 0.75
BipC, a Predicted Burkholderia pseudomallei Type 3 Secretion System Translocator Protein with Actin Binding Activity. Front Cell Infect Microbiol (2017) 0.75
Antibodies against In Vivo-Expressed Antigens Are Sufficient To Protect against Lethal Aerosol Infection with Burkholderia mallei and Burkholderia pseudomallei. Infect Immun (2017) 0.75
Tularemia. Clin Microbiol Rev (2002) 8.51
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Proc Natl Acad Sci U S A (2004) 7.30
The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet (2005) 6.22
Tularaemia: bioterrorism defence renews interest in Francisella tularensis. Nat Rev Microbiol (2004) 5.38
An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Mol Microbiol (2002) 3.23
Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guérin mutants that secrete listeriolysin. J Clin Invest (2005) 3.19
Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis. J Clin Microbiol (2003) 3.08
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84
Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis. Infect Immun (2003) 2.79
Absence of Yersinia pestis-specific DNA in human teeth from five European excavations of putative plague victims. Microbiology (2004) 2.75
Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. Genome Res (2003) 2.51
Complementary activities of SseJ and SifA regulate dynamics of the Salmonella typhimurium vacuolar membrane. Mol Microbiol (2002) 2.41
Characterization of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 ORFs and mutants with altered virulence. Microbiology (2002) 2.23
ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies. Infect Immun (2004) 2.15
Actin-dependent movement of bacterial pathogens. Nat Rev Microbiol (2006) 2.13
A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens. Proc Natl Acad Sci U S A (2009) 2.10
Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis. Genome Biol (2009) 2.04
Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol (2010) 1.84
Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei. Mol Microbiol (2005) 1.83
Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis. J Med Microbiol (2004) 1.82
A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J Bacteriol (2003) 1.78
Optimisation of bioluminescent reporters for use with mycobacteria. PLoS One (2010) 1.75
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J Biol Chem (2006) 1.72
Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutant. J Bacteriol (2005) 1.71
From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis. Bioinformatics (2007) 1.68
A critical role for neutrophils in resistance to experimental infection with Burkholderia pseudomallei. J Infect Dis (2006) 1.68
A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am J Pathol (2007) 1.67
A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence. PLoS Pathog (2010) 1.65
Direct repeat-mediated deletion of a type IV pilin gene results in major virulence attenuation of Francisella tularensis. Mol Microbiol (2006) 1.65
Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. J Immunol (2010) 1.65
A recombinant carboxy-terminal domain of the protective antigen of Bacillus anthracis protects mice against anthrax infection. Infect Immun (2002) 1.60
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis (2005) 1.56
Clostridium perfringens epsilon-toxin shows structural similarity to the pore-forming toxin aerolysin. Nat Struct Mol Biol (2004) 1.55
Construction and phenotypic characterization of an auxotrophic mutant of Mycobacterium tuberculosis defective in L-arginine biosynthesis. Infect Immun (2002) 1.55
Characterization of the O antigen gene cluster and structural analysis of the O antigen of Francisella tularensis subsp. tularensis. J Med Microbiol (2003) 1.48
Burkholderia pseudomallei: animal models of infection. Trans R Soc Trop Med Hyg (2008) 1.48
Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol (2013) 1.45
Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters. PLoS One (2010) 1.44
The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. Infect Immun (2006) 1.42
Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens. Trends Microbiol (2008) 1.39
Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB. J Bacteriol (2005) 1.38
Discrimination of human pathogenic subspecies of Francisella tularensis by using restriction fragment length polymorphism. J Clin Microbiol (2003) 1.38
Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis. J Med Microbiol (2002) 1.37
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence. Mol Microbiol (2004) 1.34
A type IV pilin, PilA, Contributes To Adherence of Burkholderia pseudomallei and virulence in vivo. Infect Immun (2005) 1.34
Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32
Cutting edge: conventional dendritic cells are the critical APC required for the induction of experimental cerebral malaria. J Immunol (2007) 1.31
A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence. Proc Natl Acad Sci U S A (2005) 1.31
Inhibition of type III secretion in Salmonella enterica serovar Typhimurium by small-molecule inhibitors. Antimicrob Agents Chemother (2007) 1.31
Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes. PLoS Negl Trop Dis (2012) 1.28
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A. Science (2011) 1.27
Identification of the Salmonella enterica serotype typhimurium SipA domain responsible for inducing neutrophil recruitment across the intestinal epithelium. Cell Microbiol (2007) 1.24
A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins. J Infect Dis (2006) 1.24
Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. Microbiology (2009) 1.23
Synergistic protection of mice against plague with monoclonal antibodies specific for the F1 and V antigens of Yersinia pestis. Infect Immun (2003) 1.23
Salmonella vaccines for use in humans: present and future perspectives. FEMS Microbiol Rev (2002) 1.22
Francisella tularensis vaccines. FEMS Immunol Med Microbiol (2007) 1.19
Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis. BMC Microbiol (2011) 1.19
Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. Mol Microbiol (2002) 1.15
Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis. Infect Immun (2007) 1.15
Vaccination strategies for Francisella tularensis. Adv Drug Deliv Rev (2005) 1.15
The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection. Infect Immun (2006) 1.14
Efficacy of the live attenuated Francisella tularensis vaccine (LVS) in a murine model of disease. Vaccine (2005) 1.14
Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity. J Infect Dis (2010) 1.13
Characterization and deposition of respirable large- and small-particle bioaerosols. Appl Environ Microbiol (2008) 1.13
Interactions of the type III secretion pathway proteins LcrV and LcrG from Yersinia pestis are mediated by coiled-coil domains. J Biol Chem (2002) 1.12
The case for hypervirulence through gene deletion in Mycobacterium tuberculosis. Trends Microbiol (2008) 1.11
Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis. PLoS Pathog (2008) 1.11
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Proc Natl Acad Sci U S A (2005) 1.11
Global map of growth-regulated gene expression in Burkholderia pseudomallei, the causative agent of melioidosis. J Bacteriol (2006) 1.11
Experimental respiratory anthrax infection in the common marmoset (Callithrix jacchus). Int J Exp Pathol (2008) 1.10
Development of vaccines against burkholderia pseudomallei. Front Microbiol (2011) 1.10
Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4. PLoS One (2007) 1.09
Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis. Infect Immun (2006) 1.08
Oral immunization with a dam mutant of Yersinia pseudotuberculosis protects against plague. Microbiology (2005) 1.08