Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMID 20113177)

Published in J Infect Dis on March 01, 2010

Authors

Olivia L Champion1, Andrey V Karlyshev, Nicola J Senior, Martin Woodward, Roberto La Ragione, Sarah L Howard, Brendan W Wren, Richard W Titball

Author Affiliations

1: School of Biosciences, University of Exeter, Exeter EX4 4QD, United Kingdom.

Articles citing this

Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screening. PLoS Pathog (2014) 1.10

Campylobacter polysaccharide capsules: virulence and vaccines. Front Cell Infect Microbiol (2012) 1.08

The polysaccharide capsule of Campylobacter jejuni modulates the host immune response. Infect Immun (2012) 1.05

The Campylobacter jejuni transcriptional regulator Cj1556 plays a role in the oxidative and aerobic stress response and is important for bacterial survival in vivo. J Bacteriol (2011) 1.05

Legionella pneumophila pathogenesis in the Galleria mellonella infection model. Infect Immun (2012) 0.99

Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. Infect Immun (2012) 0.98

Different contributions of HtrA protease and chaperone activities to Campylobacter jejuni stress tolerance and physiology. Appl Environ Microbiol (2010) 0.97

HtrA chaperone activity contributes to host cell binding in Campylobacter jejuni. Gut Pathog (2011) 0.91

Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. PLoS One (2014) 0.90

The Campylobacter jejuni NCTC11168 capsule prevents excessive cytokine production by dendritic cells. Med Microbiol Immunol (2011) 0.86

Campylobacter jejuni serine protease HtrA plays an important role in heat tolerance, oxygen resistance, host cell adhesion, invasion, and transmigration. Eur J Microbiol Immunol (Bp) (2015) 0.86

The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice. Infect Immun (2013) 0.85

Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing. Virulence (2016) 0.85

The Campylobacter jejuni MarR-like transcriptional regulators RrpA and RrpB both influence bacterial responses to oxidative and aerobic stresses. Front Microbiol (2015) 0.82

The virulence of Salmonella enterica Serovar Typhimurium in the insect model galleria mellonella is impaired by mutations in RNase E and RNase III. Appl Environ Microbiol (2013) 0.80

Common duckweed (Lemna minor) is a versatile high-throughput infection model for the Burkholderia cepacia complex and other pathogenic bacteria. PLoS One (2013) 0.79

Effect of environmental stress factors on the uptake and survival of Campylobacter jejuni in Acanthamoeba castellanii. BMC Microbiol (2012) 0.78

Galleria mellonella as a model host for microbiological and toxin research. Virulence (2016) 0.78

A PAS domain-containing regulator controls flagella-flagella interactions in Campylobacter jejuni. Front Microbiol (2015) 0.78

Pancreatic Amylase Is an Environmental Signal for Regulation of Biofilm Formation and Host Interaction in Campylobacter jejuni. Infect Immun (2015) 0.78

Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori. BMC Microbiol (2014) 0.78

Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation. FEBS Open Bio (2014) 0.77

Heterogeneity in the Infection Biology of Campylobacter jejuni Isolates in Three Infection Models Reveals an Invasive and Virulent Phenotype in a ST21 Isolate from Poultry. PLoS One (2015) 0.77

The Campylobacter jejuni Ferric Uptake Regulator Promotes Acid Survival and Cross-Protection against Oxidative Stress. Infect Immun (2016) 0.77

Genetic import and phenotype specific alleles associated with hyper-invasion in Campylobacter jejuni. BMC Genomics (2015) 0.76

Draft Genome Sequence of Campylobacter jejuni 11168H. Genome Announc (2017) 0.75

The Campylobacter jejuni Oxidative Stress Regulator RrpB Is Associated with a Genomic Hypervariable Region and Altered Oxidative Stress Resistance. Front Microbiol (2016) 0.75

Virulence Characterisation of Salmonella enterica Isolates of Differing Antimicrobial Resistance Recovered from UK Livestock and Imported Meat Samples. Front Microbiol (2016) 0.75

Phase variable changes in the position of O-methyl phosphoramidate modifications on the polysaccharide capsule of Campylobacter jejuni modulate serum resistance. J Bacteriol (2017) 0.75

Articles by these authors

Tularemia. Clin Microbiol Rev (2002) 8.51

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Proc Natl Acad Sci U S A (2004) 7.30

The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet (2005) 6.22

Tularaemia: bioterrorism defence renews interest in Francisella tularensis. Nat Rev Microbiol (2004) 5.38

Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat Genet (2012) 4.10

N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science (2002) 4.04

Protein glycosylation in bacterial mucosal pathogens. Nat Rev Microbiol (2005) 3.75

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol (2009) 3.66

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infect Immun (2009) 3.36

The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. PLoS Genet (2006) 3.33

Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A (2010) 3.18

Bacterial pathogenomics. Nature (2007) 3.16

Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis. J Clin Microbiol (2003) 3.08

Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84

Absence of Yersinia pestis-specific DNA in human teeth from five European excavations of putative plague victims. Microbiology (2004) 2.75

Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. Genome Res (2003) 2.51

The role of prophage-like elements in the diversity of Salmonella enterica serovars. J Mol Biol (2004) 2.45

Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence. BMC Genomics (2007) 2.31

Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology (2004) 2.28

Bacterial epidemiology and biology--lessons from genome sequencing. Genome Biol (2011) 2.18

Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol (2005) 2.16

ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies. Infect Immun (2004) 2.15

Campylobacter--a tale of two protein glycosylation systems. Trends Microbiol (2003) 2.10

A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens. Proc Natl Acad Sci U S A (2009) 2.10

Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proc Natl Acad Sci U S A (2005) 2.04

The Clostridium difficile spo0A gene is a persistence and transmission factor. Infect Immun (2012) 2.02

A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni. Microbiology (2002) 1.84

Parallel independent evolution of pathogenicity within the genus Yersinia. Proc Natl Acad Sci U S A (2014) 1.83

Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis. J Med Microbiol (2004) 1.82

Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. Mol Microbiol (2005) 1.79

Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. Infect Immun (2004) 1.77

From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis. Bioinformatics (2007) 1.68

A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence. PLoS Pathog (2010) 1.65

Direct repeat-mediated deletion of a type IV pilin gene results in major virulence attenuation of Francisella tularensis. Mol Microbiol (2006) 1.65

Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. Mol Microbiol (2002) 1.62

A recombinant carboxy-terminal domain of the protective antigen of Bacillus anthracis protects mice against anthrax infection. Infect Immun (2002) 1.60

Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis (2005) 1.56

Clostridium perfringens epsilon-toxin shows structural similarity to the pore-forming toxin aerolysin. Nat Struct Mol Biol (2004) 1.55

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. J Med Microbiol (2008) 1.54

Effect of chicken meat environment on gene expression of Campylobacter jejuni and its relevance to survival in food. Int J Food Microbiol (2010) 1.49

Characterization of the O antigen gene cluster and structural analysis of the O antigen of Francisella tularensis subsp. tularensis. J Med Microbiol (2003) 1.48

Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol (2013) 1.45

Invertebrates as a source of emerging human pathogens. Nat Rev Microbiol (2004) 1.45

The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. Infect Immun (2006) 1.42

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. PLoS One (2012) 1.40

Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens. Trends Microbiol (2008) 1.39

Discrimination of human pathogenic subspecies of Francisella tularensis by using restriction fragment length polymorphism. J Clin Microbiol (2003) 1.38

Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis. J Med Microbiol (2002) 1.37

Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. Infect Immun (2009) 1.35

A type IV pilin, PilA, Contributes To Adherence of Burkholderia pseudomallei and virulence in vivo. Infect Immun (2005) 1.34

Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32

Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. J Bacteriol (2006) 1.29

Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol (2005) 1.28

Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes. PLoS Negl Trop Dis (2012) 1.28

A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A. Science (2011) 1.27

Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. Microbiology (2009) 1.23

Synergistic protection of mice against plague with monoclonal antibodies specific for the F1 and V antigens of Yersinia pestis. Infect Immun (2003) 1.23

Salmonella vaccines for use in humans: present and future perspectives. FEMS Microbiol Rev (2002) 1.22

Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. PLoS One (2012) 1.21

Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. J Med Microbiol (2008) 1.20

Explorative multifactor approach for investigating global survival mechanisms of Campylobacter jejuni under environmental conditions. Appl Environ Microbiol (2005) 1.20

Comparative phylogenomics of pathogenic bacteria by microarray analysis. Curr Opin Microbiol (2005) 1.20

Francisella tularensis vaccines. FEMS Immunol Med Microbiol (2007) 1.19

Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis. BMC Microbiol (2011) 1.19

The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome. Mol Microbiol (2007) 1.18

Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. Helicobacter (2006) 1.18

The second century of Campylobacter research: recent advances, new opportunities and old problems. Curr Opin Infect Dis (2007) 1.17

Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. J Biol Chem (2007) 1.16

Serotype differences and lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia pestis. J Bacteriol (2006) 1.16

Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. Infect Immun (2005) 1.16

Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. J Med Microbiol (2011) 1.16

Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. Mol Microbiol (2002) 1.15

Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis. Infect Immun (2007) 1.15

Vaccination strategies for Francisella tularensis. Adv Drug Deliv Rev (2005) 1.15

The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection. Infect Immun (2006) 1.14

Pathogenic potential of emergent sorbitol-fermenting Escherichia coli O157:NM. Infect Immun (2008) 1.14

Grey variants of the live vaccine strain of Francisella tularensis lack lipopolysaccharide O-antigen, show reduced ability to survive in macrophages and do not induce protective immunity in mice. Vaccine (2005) 1.14

Efficacy of the live attenuated Francisella tularensis vaccine (LVS) in a murine model of disease. Vaccine (2005) 1.14

Gene content and diversity of the loci encoding biosynthesis of capsular polysaccharides of the 15 serovar reference strains of Haemophilus parasuis. J Bacteriol (2013) 1.13

Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection. PLoS One (2010) 1.13

Campylobacter jejuni-mediated disease pathogenesis: an update. Trans R Soc Trop Med Hyg (2007) 1.13

Characterization and deposition of respirable large- and small-particle bioaerosols. Appl Environ Microbiol (2008) 1.13

Interactions of the type III secretion pathway proteins LcrV and LcrG from Yersinia pestis are mediated by coiled-coil domains. J Biol Chem (2002) 1.12

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. Cell Microbiol (2007) 1.11

Global map of growth-regulated gene expression in Burkholderia pseudomallei, the causative agent of melioidosis. J Bacteriol (2006) 1.11

The Campylobacter jejuni glycome. FEMS Microbiol Rev (2005) 1.11

Development of vaccines against burkholderia pseudomallei. Front Microbiol (2011) 1.10

Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4. PLoS One (2007) 1.09

Oral immunization with a dam mutant of Yersinia pseudotuberculosis protects against plague. Microbiology (2005) 1.08

Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis. Infect Immun (2006) 1.08

Experimental aerogenic Burkholderia mallei (glanders) infection in the BALB/c mouse. J Med Microbiol (2003) 1.07