Published in Biophys J on August 01, 2004
The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis. Proc Natl Acad Sci U S A (2007) 1.41
Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers. Proc Natl Acad Sci U S A (2011) 1.07
Roles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger. J Biol Chem (2009) 1.03
Structure and dynamics of Ca2+-binding domain 1 of the Na+/Ca2+ exchanger in the presence and in the absence of Ca2+. J Mol Biol (2008) 1.00
Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1. J Biol Chem (2010) 0.93
Sodium-calcium exchange does not require allosteric calcium activation at high cytosolic sodium concentrations. J Physiol (2006) 0.93
Ca2+ regulation of ion transport in the Na+/Ca2+ exchanger. J Biol Chem (2012) 0.88
Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions. J Biol Chem (2009) 0.87
Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol (2008) 0.84
Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange. EMBO Rep (2007) 0.83
Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes. J Physiol (2013) 0.80
Structural changes in the cytoplasmic pore of the Kir1.1 channel during pHi-gating probed by FRET. J Biomed Sci (2009) 0.78
Modeling Na(+)-Ca(2+) exchange in the heart: Allosteric activation, spatial localization, sparks and excitation-contraction coupling. J Mol Cell Cardiol (2016) 0.78
Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
FRAP, FLIM, and FRET: Detection and analysis of cellular dynamics on a molecular scale using fluorescence microscopy. Mol Reprod Dev (2015) 0.75
The green fluorescent protein. Annu Rev Biochem (1998) 34.17
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature (1997) 18.83
Fluorescence energy transfer as a spectroscopic ruler. Annu Rev Biochem (1978) 11.41
A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am J Physiol (1985) 4.81
Preassociation of calmodulin with voltage-gated Ca(2+) channels revealed by FRET in single living cells. Neuron (2001) 4.28
Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Curr Biol (2000) 2.79
Sodium-calcium exchange: a molecular perspective. Annu Rev Physiol (2000) 2.40
Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J Gen Physiol (1992) 2.25
Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain. J Gen Physiol (1995) 1.95
Sodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca. J Gen Physiol (1989) 1.94
Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation. J Gen Physiol (1992) 1.92
Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J (1995) 1.82
Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger. J Biol Chem (1994) 1.72
Cytosolic free magnesium modulates Na/Ca exchange currents in pig myocytes. Cardiovasc Res (2002) 1.54
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. Proc Natl Acad Sci U S A (2000) 1.51
Calcium influx in internally dialyzed squid giant axons. J Gen Physiol (1979) 1.48
A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchanger. J Biol Chem (1999) 1.45
Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrations. J Gen Physiol (2003) 1.13
Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1. Circ Res (2004) 2.82
The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides. Circ Res (2002) 1.52
The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif. J Biol Chem (2006) 1.42
The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis. Proc Natl Acad Sci U S A (2007) 1.41
Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux. Circ Res (2005) 1.38
Enhanced learning and memory in mice lacking Na+/Ca2+ exchanger 2. Neuron (2003) 1.35
Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury. Circ Res (2005) 1.32
The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension (2008) 1.32
The Na+/Ca2+ exchange molecule: an overview. Ann N Y Acad Sci (2002) 1.28
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A (2005) 1.24
Regulation of cardiac L-type Ca2+ current in Na+-Ca2+ exchanger knockout mice: functional coupling of the Ca2+ channel and the Na+-Ca2+ exchanger. Biophys J (2006) 1.23
Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors. Circ Res (2002) 1.20
Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice. J Physiol (2010) 1.16
Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger. J Card Fail (2007) 1.11
Mutational analysis of the alpha-1 repeat of the cardiac Na(+)-Ca2+ exchanger. J Biol Chem (2004) 1.07
Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers. Proc Natl Acad Sci U S A (2011) 1.07
Intermolecular cross-linking of Na+-Ca2+ exchanger proteins: evidence for dimer formation. Biochemistry (2008) 1.05
Phospholemman and beta-adrenergic stimulation in the heart. Am J Physiol Heart Circ Physiol (2009) 1.05
Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling. J Physiol (2003) 1.05
Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol (2010) 1.05
Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice. Am J Physiol Cell Physiol (2006) 1.04
Roles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger. J Biol Chem (2009) 1.03
Myocardial function with reduced expression of the sodium-calcium exchanger. J Card Fail (2010) 1.03
Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart. Biophys J (2010) 1.01
The cardiac sodium pump: structure and function. Basic Res Cardiol (2002) 1.00
The sodium/calcium exchanger family-SLC8. Pflugers Arch (2003) 0.97
Na(+)--Ca2+ exchange in the regulation of cardiac excitation-contraction coupling. Cardiovasc Res (2005) 0.96
Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures. Brain Res Mol Brain Res (2002) 0.96
Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange. Cell Calcium (2003) 0.96
Localization of sarcolemmal proteins to lipid rafts in the myocardium. Cell Calcium (2007) 0.95
The topology of the cardiac Na⁺/Ca²⁺ exchanger, NCX1. J Mol Cell Cardiol (2013) 0.94
Structure and functional analysis of a Ca2+ sensor mutant of the Na+/Ca2+ exchanger. J Biol Chem (2009) 0.93
Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circ Res (2012) 0.93
Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy. Am J Physiol Heart Circ Physiol (2012) 0.93
Na+/Ca2+ exchanger knockout mice: plasticity of cardiac excitation-contraction coupling. Ann N Y Acad Sci (2007) 0.93
Helix packing of the cardiac Na+-Ca2+ exchanger: proximity of transmembrane segments 1, 2, and 6. J Biol Chem (2006) 0.92
Shedding light on the Na+/Ca2+ exchanger. Ann N Y Acad Sci (2007) 0.91
Genetic manipulation of cardiac Na+/Ca2+ exchange expression. Biochem Biophys Res Commun (2004) 0.91
Toward a topological model of the NCX1 exchanger. Ann N Y Acad Sci (2002) 0.90
Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. PLoS One (2013) 0.90
What we know about the structure of NCX1 and how it relates to its function. Ann N Y Acad Sci (2007) 0.90
Cardiac sodium-calcium exchange and efficient excitation-contraction coupling: implications for heart disease. Adv Exp Med Biol (2013) 0.90
Na/Ca exchange and contraction of the heart. J Mol Cell Cardiol (2013) 0.89
Vaults are dynamically unconstrained cytoplasmic nanoparticles capable of half vault exchange. ACS Nano (2010) 0.89
Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons. Mol Pharmacol (2009) 0.88
Increased tolerance to ischemic neuronal damage by knockdown of Na+-Ca2+ exchanger isoform 1. Ann N Y Acad Sci (2007) 0.88
Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction. Am J Physiol Heart Circ Physiol (2002) 0.88
Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms. Basic Res Cardiol (2012) 0.88
A concerted role of Na+ -K+ -Cl- cotransporter and Na+/Ca2+ exchanger in ischemic damage. J Cereb Blood Flow Metab (2007) 0.87
Homozygous overexpression of the Na+-Ca2+ exchanger in mice: evidence for increased transsarcolemmal Ca2+ fluxes. Ann N Y Acad Sci (2007) 0.86
Xenopus oocyte plasma membrane sheets for FRET analysis. Am J Physiol Cell Physiol (2006) 0.86
Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Mol Cell Biol (2014) 0.86
Interactions between Ca2+ binding domains of the Na+-Ca2+ exchanger and secondary regulation. Channels (Austin) (2011) 0.85
Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts. Dev Dyn (2010) 0.85
The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia. J Appl Physiol (1985) (2010) 0.85
Transmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkers. Biochemistry (2010) 0.84
Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol (2008) 0.84
Activation of L-type Ca2+ channels by protein kinase C is reduced in smooth muscle-specific Na+/Ca2+ exchanger knockout mice. Am J Physiol Heart Circ Physiol (2010) 0.83
Ca2+ sparks induced by Na/Ca exchange. Cell Calcium (2003) 0.82
Effects of Na+-Ca2+ exchange expression on excitation-contraction coupling in genetically modified mice. Ann N Y Acad Sci (2005) 0.81
How does regulatory Ca2+ regulate the Na+-Ca2+ exchanger? Channels (Austin) (2008) 0.80
Partial rescue of the Na+-Ca2+ exchanger (NCX1) knock-out mouse by transgenic expression of NCX1. Exp Mol Med (2003) 0.80
Characterization and purification of a Na+/Ca2+ exchanger from an archaebacterium. J Biol Chem (2012) 0.79
Fluorescent Na+-Ca+ exchangers: electrophysiological and optical characterization. J Biol Chem (2006) 0.79
NCX1: mechanism of transport. Adv Exp Med Biol (2013) 0.79
20 years from NCX purification and cloning: milestones. Adv Exp Med Biol (2013) 0.79
Cyclosporin A regulates sodium-calcium exchanger (NCX1) gene expression in vitro and cardiac hypertrophy in NCX1 transgenic mice. Ann N Y Acad Sci (2002) 0.78
Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation. Mol Pharmacol (2004) 0.77
Na(+)-Ca(2+) exchange: three new tools. Circ Res (2002) 0.77
Sodium-calcium exchanger overexpression in the heart--insights from a transgenic mouse model. Basic Res Cardiol (2002) 0.76
Structural biology. It's all in the symmetry. Science (2012) 0.76
Activation of the cardiac Na+/Ca2+ exchanger by DEPC. Ann N Y Acad Sci (2002) 0.75
Ischemic tolerance of homozygous transgenic mouse hearts overexpressing the sodium-calcium exchanger. Ann N Y Acad Sci (2002) 0.75
Overexpression of Na+/Ca2+ exchanger attenuates postinfarcted myocardial dysfunction. Ann N Y Acad Sci (2002) 0.75
Transmembrane segments I, II, and VI of the canine cardiac Na+/Ca2+ exchanger are in proximity. Ann N Y Acad Sci (2007) 0.75