The sodium/calcium exchanger family-SLC8.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 12734757)

Published in Pflugers Arch on May 07, 2003

Authors

Beate D Quednau1, Debora A Nicoll, Kenneth D Philipson

Author Affiliations

1: Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1760, USA.

Articles citing this

The Concise Guide to PHARMACOLOGY 2013/14: transporters. Br J Pharmacol (2013) 2.07

Analysis and update of the human solute carrier (SLC) gene superfamily. Hum Genomics (2009) 1.62

Cellular magnesium homeostasis. Arch Biochem Biophys (2011) 1.46

The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension (2008) 1.32

Nuclear sphingolipids: metabolism and signaling. J Lipid Res (2008) 1.05

Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol (2010) 1.05

Expression of the sodium/calcium/potassium exchanger, NCKX4, in ameloblasts. Cells Tissues Organs (2012) 1.00

Signaling mechanisms that link salt retention to hypertension: endogenous ouabain, the Na(+) pump, the Na(+)/Ca(2+) exchanger and TRPC proteins. Biochim Biophys Acta (2010) 0.99

Gene expression analysis of the embryonic subplate. Cereb Cortex (2011) 0.98

cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism. Cell Calcium (2014) 0.88

The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia. J Appl Physiol (1985) (2010) 0.85

Renal tubular transport and the genetic basis of hypertensive disease. Clin Exp Nephrol (2005) 0.85

The properties, distribution and function of Na(+)-Ca(2+) exchanger isoforms in rat cutaneous sensory neurons. J Physiol (2014) 0.83

Sodium-calcium exchangers in rat trigeminal ganglion neurons. Mol Pain (2013) 0.81

Ion dynamics during seizures. Front Cell Neurosci (2015) 0.80

Identification and apical membrane localization of an electrogenic Na⁺/Ca²⁺ exchanger NCX2a likely to be involved in renal Ca²⁺ excretion by seawater fish. Am J Physiol Regul Integr Comp Physiol (2011) 0.78

Involvement of Na+/Ca2+ exchanger in migration and contraction of rat cultured tendon fibroblasts. J Physiol (2009) 0.78

Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII. Biosci Rep (2013) 0.77

Change in intracellular pH causes the toxic Ca2+ entry via NCX1 in neuron- and glia-derived cells. Cell Mol Neurobiol (2009) 0.77

Electrophysiological demonstration of Na+/Ca2+ exchange in bovine articular chondrocytes. Biorheology (2006) 0.76

Pharmacological evidence that potentiation of plasmalemmal Ca(2+)-extrusion is functionally coupled to inhibition of SR Ca(2+)-ATPases in vascular smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.76

A novel mechanism underlies atrazine toxicity in quails (Coturnix Coturnix coturnix): triggering ionic disorder via disruption of ATPases. Oncotarget (2016) 0.75

Articles cited by this

The influence of calcium on sodium efflux in squid axons. J Physiol (1969) 9.43

The dependence of calcium efflux from cardiac muscle on temperature and external ion composition. J Physiol (1968) 8.13

Sodium/calcium exchange: its physiological implications. Physiol Rev (1999) 5.42

Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2. Science (1996) 4.36

Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circ Res (1999) 3.35

Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. Science (1990) 2.95

Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes. Biophys J (2000) 2.83

Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J (2001) 2.78

Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium. Circulation (1999) 2.45

Abnormalities of calcium cycling in the hypertrophied and failing heart. J Mol Cell Cardiol (2000) 2.25

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J Gen Physiol (1992) 2.25

The stoichiometry of the cardiac sodium-calcium exchange system. J Biol Chem (1984) 2.24

Enhanced Ca(2+)-activated Na(+)-Ca(2+) exchange activity in canine pacing-induced heart failure. Circ Res (2000) 2.21

Na+-Ca2+ exchange activity is localized in the T-tubules of rat ventricular myocytes. Circ Res (2002) 2.05

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain. J Gen Physiol (1995) 1.95

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation. J Gen Physiol (1992) 1.92

Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat. Am J Physiol (1997) 1.89

Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J Cell Biol (1992) 1.73

SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. J Pharmacol Exp Ther (2001) 1.72

Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. J Biol Chem (1991) 1.72

Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger. J Biol Chem (1994) 1.72

Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. Proc Natl Acad Sci U S A (1993) 1.69

Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am J Physiol (1992) 1.64

Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3. J Biol Chem (1996) 1.57

Calx, a Na-Ca exchanger gene of Drosophila melanogaster. Proc Natl Acad Sci U S A (1997) 1.54

Cloning and characterization of a novel Mg(2+)/H(+) exchanger. EMBO J (1999) 1.53

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides. Circ Res (2002) 1.52

Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger. J Biol Chem (1994) 1.48

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat. J Biol Chem (2000) 1.48

A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchanger. J Biol Chem (1999) 1.45

Mutation of amino acid residues in the putative transmembrane segments of the cardiac sarcolemmal Na+-Ca2+ exchanger. J Biol Chem (1996) 1.39

Sodium-calcium exchange in plasma membrane vesicles. Annu Rev Physiol (1985) 1.39

Cardiac-specific expression and hypertrophic upregulation of the feline Na(+)-Ca(2+) exchanger gene H1-promoter in a transgenic mouse model. Circ Res (2002) 1.35

The cardiac Na+-Ca2+ exchanger binds to the cytoskeletal protein ankyrin. J Biol Chem (1993) 1.34

Regulation of cardiac Na(+)-Ca2+ exchanger by the endogenous XIP region. J Gen Physiol (1997) 1.31

Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3). Am J Physiol (1998) 1.28

Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger. J Gen Physiol (1997) 1.28

Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger. J Biol Chem (1994) 1.25

Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice. Circ Res (1999) 1.24

Effects of overexpression of the Na+-Ca2+ exchanger on [Ca2+]i transients in murine ventricular myocytes. Circ Res (1998) 1.23

Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms. J Biol Chem (1994) 1.21

Stoichiometry of Na+-Ca2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes. J Physiol (2000) 1.21

Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors. Circ Res (2002) 1.20

Na+-Ca2+ exchange and sarcoplasmic reticular Ca2+ regulation in ventricular myocytes from transgenic mice overexpressing the Na+-Ca2+ exchanger. J Physiol (1998) 1.19

Na+-Ca2+ exchanger remodeling in pressure overload cardiac hypertrophy. J Biol Chem (2001) 1.18

Interaction of PIP(2) with the XIP region of the cardiac Na/Ca exchanger. Am J Physiol Cell Physiol (2000) 1.15

Evidence for functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in failing human myocardium. Circulation (1996) 1.14

Ionic regulatory properties of brain and kidney splice variants of the NCX1 Na(+)-Ca(2+) exchanger. J Gen Physiol (1999) 1.13

Differential inhibition of Na+/Ca2+ exchanger isoforms by divalent cations and isothiourea derivative. Am J Physiol (1998) 1.11

The Na+/Ca2+ exchanger NCX1 has oppositely oriented reentrant loop domains that contain conserved aspartic acids whose mutation alters its apparent Ca2+ affinity. J Biol Chem (2000) 1.10

Helix packing of functionally important regions of the cardiac Na(+)-Ca(2+) exchanger. J Biol Chem (2001) 1.07

Distinction between the two basic mechanisms of cation transport in the cardiac Na(+)-Ca2+ exchange system. Biochemistry (1990) 1.06

Location of calcium transporters at presynaptic terminals. Eur J Neurosci (2000) 1.05

The Na+ -Ca2+ exchanger is essential for embryonic heart development in mice. Mol Cells (2000) 1.05

Impaired contractile performance of cultured rabbit ventricular myocytes after adenoviral gene transfer of Na(+)-Ca(2+) exchanger. Circ Res (2000) 1.03

The role of GATA, CArG, E-box, and a novel element in the regulation of cardiac expression of the Na+-Ca2+ exchanger gene. J Biol Chem (1999) 1.02

Rapid expression of the Na(+)-Ca2+ exchanger in response to cardiac pressure overload. Am J Physiol (1993) 0.99

Sodium-calcium exchanger is initially expressed in a heart-restricted pattern within the early mouse embryo. Mech Dev (1999) 0.99

Cloning of cardiac, kidney, and brain promoters of the feline ncx1 gene. J Biol Chem (1997) 0.97

Topology of a functionally important region of the cardiac Na+/Ca2+ exchanger. J Biol Chem (1998) 0.97

Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures. Brain Res Mol Brain Res (2002) 0.96

Functional analysis of a disulfide bond in the cardiac Na(+)-Ca(2+) exchanger. J Biol Chem (2000) 0.96

Inhibitors of sodium-calcium exchange: identification and development of probes of transport activity. Biochim Biophys Acta (1989) 0.95

Na+-dependent alkaline earth metal uptake in cardiac sarcolemmal vesicles. Biochim Biophys Acta (1985) 0.94

Presynaptic localization of sodium/calcium exchangers in neuromuscular preparations. J Neurosci (1992) 0.93

Steady-state mRNA levels of the sarcolemmal Na(+)-Ca2+ exchanger peak near birth in developing rabbit and rat hearts. Circ Res (1994) 0.92

Expression of the Na(+)/Ca(2+) exchanger in skeletal muscle. Am J Physiol Cell Physiol (2001) 0.91

Distribution of the Na+/Ca2+ exchange protein in developing rabbit myocytes. Am J Physiol (1995) 0.90

Immunolocalization of the Na+/Ca2+ exchanger in rabbit kidney. Am J Physiol (1993) 0.90

Cloning of the rat aortic smooth muscle Na+/Ca2+ exchanger and tissue-specific expression of isoforms. J Biochem (1993) 0.90

Increased Na(+)-Ca(2+) exchanger in the failing heart. Circ Res (2000) 0.90

Calcineurin controls the transcription of Na+/Ca2+ exchanger isoforms in developing cerebellar neurons. J Biol Chem (2000) 0.89

Transport of magnesium by two isoforms of the Na+-Ca2+ exchanger expressed in CCL39 fibroblasts. Pflugers Arch (2000) 0.88

Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor. J Mol Cell Cardiol (2002) 0.87

Regional differences in expression of transcripts for Na+/Ca2+ exchanger isoforms in rat brain. Brain Res Mol Brain Res (1997) 0.86

Cardiac expression of the Na(+)/Ca(2+) exchanger NCX1 is GATA factor dependent. Am J Physiol (1999) 0.84

Cooperative interaction between Ca2+ binding sites in the hydrophilic loop of the Na(+)-Ca2+ exchanger. Mol Cell Biochem (1997) 0.83

Regional distribution in the rat central nervous system of a mRNA encoding a portion of the cardiac sodium/calcium exchanger isolated from cerebellar granule neurons. Brain Res Mol Brain Res (1993) 0.82

Functional role of ionic regulation of Na+/Ca2+ exchange assessed in transgenic mouse hearts. Am J Physiol (1999) 0.82

Alternative promoters and cardiac muscle cell-specific expression of the Na+/Ca2+ exchanger gene. Am J Physiol (1998) 0.81

Cyclosporin A regulates sodium-calcium exchanger (NCX1) gene expression in vitro and cardiac hypertrophy in NCX1 transgenic mice. Ann N Y Acad Sci (2002) 0.78

Enhanced gene expression of Na(+)/Ca(2+) exchanger attenuates ischemic and hypoxic contractile dysfunction. Am J Physiol Heart Circ Physiol (2000) 0.78

Ni2+ transport by the human Na+/Ca2+ exchanger expressed in Sf9 cells. Am J Physiol (1999) 0.77

Expression of the sodium/calcium exchanger in mammalian skeletal muscle cells in primary culture. Exp Cell Res (2000) 0.77

Phe-Met-Arg-Phe-NH2 (FMRFa)-related peptides inhibit Na(+)-Ca2+ exchange in cardiac sarcolemma vesicles. J Biol Chem (1993) 0.77

Sodium-calcium exchange: the phantom menace. Circ Res (1999) 0.77

Structural domains influencing sensitivity to isothiourea derivative inhibitor KB-R7943 in cardiac Nna(+)/Ca(2+) exchanger. Mol Pharmacol (2001) 0.77

Na(+)-Ca(2+) exchange in failing myocardium: friend or foe? Circ Res (2000) 0.76

A disulfide bond is required for functional assembly of NCX1 from complementary fragments. Biochem Biophys Res Commun (2001) 0.75

Articles by these authors

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1. Circ Res (2004) 2.82

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides. Circ Res (2002) 1.52

The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif. J Biol Chem (2006) 1.42

The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis. Proc Natl Acad Sci U S A (2007) 1.41

Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux. Circ Res (2005) 1.38

Enhanced learning and memory in mice lacking Na+/Ca2+ exchanger 2. Neuron (2003) 1.35

Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury. Circ Res (2005) 1.32

The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension (2008) 1.32

The Na+/Ca2+ exchange molecule: an overview. Ann N Y Acad Sci (2002) 1.28

Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A (2005) 1.24

Regulation of cardiac L-type Ca2+ current in Na+-Ca2+ exchanger knockout mice: functional coupling of the Ca2+ channel and the Na+-Ca2+ exchanger. Biophys J (2006) 1.23

Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors. Circ Res (2002) 1.20

Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice. J Physiol (2010) 1.16

Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger. J Card Fail (2007) 1.11

Conformational changes of the Ca(2+) regulatory site of the Na(+)-Ca(2+) exchanger detected by FRET. Biophys J (2004) 1.09

Mutational analysis of the alpha-1 repeat of the cardiac Na(+)-Ca2+ exchanger. J Biol Chem (2004) 1.07

Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers. Proc Natl Acad Sci U S A (2011) 1.07

Intermolecular cross-linking of Na+-Ca2+ exchanger proteins: evidence for dimer formation. Biochemistry (2008) 1.05

Phospholemman and beta-adrenergic stimulation in the heart. Am J Physiol Heart Circ Physiol (2009) 1.05

Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol (2010) 1.05

Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling. J Physiol (2003) 1.05

Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice. Am J Physiol Cell Physiol (2006) 1.04

Roles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger. J Biol Chem (2009) 1.03

Myocardial function with reduced expression of the sodium-calcium exchanger. J Card Fail (2010) 1.03

Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart. Biophys J (2010) 1.01

The cardiac sodium pump: structure and function. Basic Res Cardiol (2002) 1.00

Na(+)--Ca2+ exchange in the regulation of cardiac excitation-contraction coupling. Cardiovasc Res (2005) 0.96

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange. Cell Calcium (2003) 0.96

Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures. Brain Res Mol Brain Res (2002) 0.96

Localization of sarcolemmal proteins to lipid rafts in the myocardium. Cell Calcium (2007) 0.95

The topology of the cardiac Na⁺/Ca²⁺ exchanger, NCX1. J Mol Cell Cardiol (2013) 0.94

Structure and functional analysis of a Ca2+ sensor mutant of the Na+/Ca2+ exchanger. J Biol Chem (2009) 0.93

Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy. Am J Physiol Heart Circ Physiol (2012) 0.93

Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circ Res (2012) 0.93

Na+/Ca2+ exchanger knockout mice: plasticity of cardiac excitation-contraction coupling. Ann N Y Acad Sci (2007) 0.93

Helix packing of the cardiac Na+-Ca2+ exchanger: proximity of transmembrane segments 1, 2, and 6. J Biol Chem (2006) 0.92

Shedding light on the Na+/Ca2+ exchanger. Ann N Y Acad Sci (2007) 0.91

Genetic manipulation of cardiac Na+/Ca2+ exchange expression. Biochem Biophys Res Commun (2004) 0.91

Toward a topological model of the NCX1 exchanger. Ann N Y Acad Sci (2002) 0.90

What we know about the structure of NCX1 and how it relates to its function. Ann N Y Acad Sci (2007) 0.90

Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. PLoS One (2013) 0.90

Cardiac sodium-calcium exchange and efficient excitation-contraction coupling: implications for heart disease. Adv Exp Med Biol (2013) 0.90

Na/Ca exchange and contraction of the heart. J Mol Cell Cardiol (2013) 0.89

Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction. Am J Physiol Heart Circ Physiol (2002) 0.88

Increased tolerance to ischemic neuronal damage by knockdown of Na+-Ca2+ exchanger isoform 1. Ann N Y Acad Sci (2007) 0.88

Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms. Basic Res Cardiol (2012) 0.88

A concerted role of Na+ -K+ -Cl- cotransporter and Na+/Ca2+ exchanger in ischemic damage. J Cereb Blood Flow Metab (2007) 0.87

Homozygous overexpression of the Na+-Ca2+ exchanger in mice: evidence for increased transsarcolemmal Ca2+ fluxes. Ann N Y Acad Sci (2007) 0.86

Xenopus oocyte plasma membrane sheets for FRET analysis. Am J Physiol Cell Physiol (2006) 0.86

Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Mol Cell Biol (2014) 0.86

The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia. J Appl Physiol (1985) (2010) 0.85

Interactions between Ca2+ binding domains of the Na+-Ca2+ exchanger and secondary regulation. Channels (Austin) (2011) 0.85

Transmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkers. Biochemistry (2010) 0.84

Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol (2008) 0.84

Activation of L-type Ca2+ channels by protein kinase C is reduced in smooth muscle-specific Na+/Ca2+ exchanger knockout mice. Am J Physiol Heart Circ Physiol (2010) 0.83

Ca2+ sparks induced by Na/Ca exchange. Cell Calcium (2003) 0.82

Effects of Na+-Ca2+ exchange expression on excitation-contraction coupling in genetically modified mice. Ann N Y Acad Sci (2005) 0.81

How does regulatory Ca2+ regulate the Na+-Ca2+ exchanger? Channels (Austin) (2008) 0.80

Partial rescue of the Na+-Ca2+ exchanger (NCX1) knock-out mouse by transgenic expression of NCX1. Exp Mol Med (2003) 0.80

NCX1: mechanism of transport. Adv Exp Med Biol (2013) 0.79

Fluorescent Na+-Ca+ exchangers: electrophysiological and optical characterization. J Biol Chem (2006) 0.79

20 years from NCX purification and cloning: milestones. Adv Exp Med Biol (2013) 0.79

Characterization and purification of a Na+/Ca2+ exchanger from an archaebacterium. J Biol Chem (2012) 0.79

Cyclosporin A regulates sodium-calcium exchanger (NCX1) gene expression in vitro and cardiac hypertrophy in NCX1 transgenic mice. Ann N Y Acad Sci (2002) 0.78

Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation. Mol Pharmacol (2004) 0.77

Na(+)-Ca(2+) exchange: three new tools. Circ Res (2002) 0.77

Sodium-calcium exchanger overexpression in the heart--insights from a transgenic mouse model. Basic Res Cardiol (2002) 0.76

Structural biology. It's all in the symmetry. Science (2012) 0.76

Transmembrane segments I, II, and VI of the canine cardiac Na+/Ca2+ exchanger are in proximity. Ann N Y Acad Sci (2007) 0.75

Ischemic tolerance of homozygous transgenic mouse hearts overexpressing the sodium-calcium exchanger. Ann N Y Acad Sci (2002) 0.75

Overexpression of Na+/Ca2+ exchanger attenuates postinfarcted myocardial dysfunction. Ann N Y Acad Sci (2002) 0.75

Activation of the cardiac Na+/Ca2+ exchanger by DEPC. Ann N Y Acad Sci (2002) 0.75