Published in Acta Crystallogr D Biol Crystallogr on July 01, 1994
Profile analysis: detection of distantly related proteins. Proc Natl Acad Sci U S A (1987) 29.26
Assigning protein functions by comparative genome analysis: protein phylogenetic profiles. Proc Natl Acad Sci U S A (1999) 22.80
Detecting protein function and protein-protein interactions from genome sequences. Science (1999) 18.69
A method to identify protein sequences that fold into a known three-dimensional structure. Science (1991) 14.08
Analysis of membrane and surface protein sequences with the hydrophobic moment plot. J Mol Biol (1984) 13.69
SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science (1991) 12.93
Assessment of protein models with three-dimensional profiles. Nature (1992) 12.64
Solvation energy in protein folding and binding. Nature (1986) 10.94
DIP: the database of interacting proteins. Nucleic Acids Res (2000) 10.06
A combined algorithm for genome-wide prediction of protein function. Nature (1999) 9.99
Profile analysis. Methods Enzymol (1990) 9.40
Three-dimensional structure of membrane and surface proteins. Annu Rev Biochem (1984) 7.38
The hydrophobic moment detects periodicity in protein hydrophobicity. Proc Natl Acad Sci U S A (1984) 6.36
Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen (2000) 6.24
RANK is essential for osteoclast and lymph node development. Genes Dev (1999) 5.85
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J (1994) 5.69
Protein interaction databases. Curr Opin Biotechnol (2001) 5.22
Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med (1994) 5.20
Mining literature for protein-protein interactions. Bioinformatics (2001) 5.18
Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Atorvastatin versus Revascularization Treatment Investigators. N Engl J Med (1999) 5.09
The helical hydrophobic moment: a measure of the amphiphilicity of a helix. Nature (1982) 5.01
3D domain swapping: a mechanism for oligomer assembly. Protein Sci (1995) 4.96
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science (1990) 4.90
Ferricytochrome c. I. General features of the horse and bonito proteins at 2.8 A resolution. J Biol Chem (1971) 4.75
A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis. N Engl J Med (1996) 4.70
The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell (1989) 4.48
Domain swapping: entangling alliances between proteins. Proc Natl Acad Sci U S A (1994) 4.20
Src homology region 2 domains direct protein-protein interactions in signal transduction. Proc Natl Acad Sci U S A (1990) 4.13
The crystal structure of diphtheria toxin. Nature (1992) 3.80
Correlation of sequence hydrophobicities measures similarity in three-dimensional protein structure. J Mol Biol (1983) 3.78
Profile scanning for three-dimensional structural patterns in protein sequences. Comput Appl Biosci (1988) 3.66
Management of women with mild and moderate cervical dyskaryosis. BMJ (1994) 3.65
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. Nat Genet (1996) 3.56
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure. Biochemistry (2000) 3.46
DIP: The Database of Interacting Proteins: 2001 update. Nucleic Acids Res (2001) 3.38
Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection. J Exp Med (1992) 3.34
A small viral RNA is required for in vitro packaging of bacteriophage phi 29 DNA. Science (1987) 3.29
The structure of melittin. II. Interpretation of the structure. J Biol Chem (1982) 3.22
Atomic solvation parameters applied to molecular dynamics of proteins in solution. Protein Sci (1992) 3.05
Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles. Cell (1990) 2.95
Novel subunit-subunit interactions in the structure of glutamine synthetase. Nature (1986) 2.87
Alternative therapies used by women with breast cancer in four ethnic populations. J Natl Cancer Inst (2000) 2.87
Finding families for genomic ORFans. Bioinformatics (1999) 2.76
Hydrophobic organization of membrane proteins. Science (1989) 2.74
CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell (1993) 2.73
Sequence-structure analysis of FAD-containing proteins. Protein Sci (2001) 2.73
Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization. Science (1991) 2.71
A census of protein repeats. J Mol Biol (1999) 2.70
Protein fold recognition using sequence-derived predictions. Protein Sci (1996) 2.70
Randomized trial comparing traditional Chinese medical acupuncture, therapeutic massage, and self-care education for chronic low back pain. Arch Intern Med (2001) 2.67
Prohead and DNA-gp3-dependent ATPase activity of the DNA packaging protein gp16 of bacteriophage phi 29. J Mol Biol (1987) 2.59
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell (1992) 2.58
Where metal ions bind in proteins. Proc Natl Acad Sci U S A (1990) 2.56
Retained surgical swabs in 13 dogs. Vet Rec (2011) 2.54
Cloning determinants of pathogenesis from Pseudomonas syringae pathovar syringae. Proc Natl Acad Sci U S A (1985) 2.50
The structure of melittin in the form I crystals and its implication for melittin's lytic and surface activities. Biophys J (1982) 2.50
Enhancement of recovery from psychiatric illness by methylfolate. Br J Psychiatry (1992) 2.44
Use of complementary medicine by adult patients participating in cancer clinical trials. Oncol Nurs Forum (2000) 2.41
Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution. Science (1997) 2.38
Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells. J Exp Med (1989) 2.30
Managing oral anticoagulant therapy. Chest (2001) 2.25
Localizing proteins in the cell from their phylogenetic profiles. Proc Natl Acad Sci U S A (2000) 2.24
Three-dimensional cluster analysis identifies interfaces and functional residue clusters in proteins. J Mol Biol (2001) 2.17
Oligomer formation by 3D domain swapping: a model for protein assembly and misassembly. Adv Protein Chem (1997) 2.17
A domain-swapped RNase A dimer with implications for amyloid formation. Nat Struct Biol (2001) 2.15
IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. International Programme on Chemical Safety. Mutat Res (2000) 2.14
Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro. Mol Cell (1998) 2.13
Crystal structure of a synthetic triple-stranded alpha-helical bundle. Science (1993) 2.09
A defined system for in vitro packaging of DNA-gp3 of the Bacillus subtilis bacteriophage phi 29. Proc Natl Acad Sci U S A (1986) 2.07
Tertiary structure of plant RuBisCO: domains and their contacts. Science (1988) 2.06
B29: a member of the immunoglobulin gene superfamily exclusively expressed on beta-lineage cells. Proc Natl Acad Sci U S A (1988) 2.05
The structure of melittin. I. Structure determination and partial refinement. J Biol Chem (1982) 2.04
Transproteomic evidence of a loop-deletion mechanism for enhancing protein thermostability. J Mol Biol (1999) 2.03
Graduated compression stockings to treat acute leg pain associated with proximal DVT. A randomised controlled trial. Thromb Haemost (2014) 2.02
Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use. Nature (1976) 2.00
SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors. Mol Cell Biol (1992) 2.00
Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res (1996) 1.95
The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core. Proc Natl Acad Sci U S A (2001) 1.94
Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles. Nat Genet (2001) 1.93
The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J (1993) 1.91
Refined structure of dimeric diphtheria toxin at 2.0 A resolution. Protein Sci (1994) 1.88
Secondary structure-based profiles: use of structure-conserving scoring tables in searching protein sequence databases for structural similarities. Proteins (1991) 1.88
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes. Chem Biol (1996) 1.87
Hepatitis E virus infection among animals in northern India: an unlikely source of human disease. J Viral Hepat (2007) 1.85
Reconstruction of glutamine synthetase using computer averaging. Ultramicroscopy (1978) 1.85
An evolutionary approach to folding small alpha-helical proteins that uses sequence information and an empirical guiding fitness function. Proc Natl Acad Sci U S A (1994) 1.83
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide. Biochemistry (1996) 1.81
Assigning folds to the proteins encoded by the genome of Mycoplasma genitalium. Proc Natl Acad Sci U S A (1997) 1.81
Refined atomic model of glutamine synthetase at 3.5 A resolution. J Biol Chem (1989) 1.81
Interactions of melittin, a preprotein model, with detergents. Biochemistry (1979) 1.80
On-demand single-electron transfer between distant quantum dots. Nature (2011) 1.75
Selection of temperature-sensitive activating enzyme mutants in Escherichia coli. J Bacteriol (1968) 1.75
Assessing the performance of fold recognition methods by means of a comprehensive benchmark. Pac Symp Biocomput (1996) 1.75
Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. Proc Natl Acad Sci U S A (1989) 1.74
A 3D-1D substitution matrix for protein fold recognition that includes predicted secondary structure of the sequence. J Mol Biol (1997) 1.72
Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge. J Virol (2003) 1.70
Doxorubicin-based chemotherapy for the palliative treatment of adult patients with locally advanced or metastatic soft tissue sarcoma. Cochrane Database Syst Rev (2003) 1.70
Regulation of the phage phi 29 prohead shape and size by the portal vertex. Virology (1991) 1.70