Published in J Biol Chem on August 17, 2004
Synaptic and nonsynaptic localization of GABAA receptors containing the alpha5 subunit in the rat brain. J Comp Neurol (2006) 1.30
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities. J Physiol (2007) 1.04
In the developing rat hippocampus a tonic GABAA-mediated conductance selectively enhances the glutamatergic drive of principal cells. J Physiol (2007) 0.89
Proton modulation of recombinant GABA(A) receptors: influence of GABA concentration and the beta subunit TM2-TM3 domain. J Physiol (2005) 0.89
Anterior thalamic lesions produce chronic and profuse transcriptional de-regulation in retrosplenial cortex: A model of retrosplenial hypoactivity and covert pathology. Thalamus Relat Syst (2008) 0.83
Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus. Front Pharmacol (2012) 0.81
The short splice variant of the gamma 2 subunit acts as an external modulator of GABA(A) receptor function. J Neurosci (2010) 0.81
Maturation of the GABAergic transmission in normal and pathologic motoneurons. Neural Plast (2011) 0.81
Tyrosine phosphorylation of GABAA receptor γ2-subunit regulates tonic and phasic inhibition in the thalamus. J Neurosci (2013) 0.80
Differential drug responses on native GABA(A) receptors revealing heterogeneity in extrasynaptic populations in cultured hippocampal neurons. J Membr Biol (2009) 0.78
Modulation of the input-output function by GABAA receptor-mediated currents in rat oculomotor nucleus motoneurons. J Physiol (2014) 0.76
Muscarinic Long-Term Enhancement of Tonic and Phasic GABAA Inhibition in Rat CA1 Pyramidal Neurons. Front Cell Neurosci (2016) 0.75
Hippocampal Hyperexcitability is Modulated by Microtubule-Active Agent: Evidence from In Vivo and In Vitro Epilepsy Models in the Rat. Front Cell Neurosci (2016) 0.75
Tonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy. Mol Neurobiol (2015) 0.75
International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacol Rev (2008) 4.49
GABA A receptors: subtypes provide diversity of function and pharmacology. Neuropharmacology (2008) 3.49
GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain. J Comp Neurol (2002) 2.11
Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. Eur J Neurosci (2010) 2.03
BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus. J Physiol (2004) 1.89
At immature mossy-fiber-CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA. J Neurosci (2009) 1.66
Deficits in phosphorylation of GABA(A) receptors by intimately associated protein kinase C activity underlie compromised synaptic inhibition during status epilepticus. J Neurosci (2008) 1.63
From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nat Neurosci (2007) 1.62
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders. Neuroscientist (2012) 1.59
Alterations of GABAergic signaling in autism spectrum disorders. Neural Plast (2011) 1.56
Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. J Pharmacol Exp Ther (2002) 1.56
Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol Cell (2004) 1.55
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptors. Proc Natl Acad Sci U S A (2006) 1.52
GABA-mediated giant depolarizing potentials as coincidence detectors for enhancing synaptic efficacy in the developing hippocampus. Proc Natl Acad Sci U S A (2004) 1.49
Distribution of alpha1, alpha4, gamma2, and delta subunits of GABAA receptors in hippocampal granule cells. Brain Res (2004) 1.41
Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function. Mol Pharmacol (2005) 1.41
Anxioselective anxiolytics: additional perspective. Trends Pharmacol Sci (2013) 1.39
Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current. J Neurosci (2008) 1.32
Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala. Proc Natl Acad Sci U S A (2011) 1.31
Cultured Hippocampal Pyramidal Neurons Express Two Kinds of GABAA Receptors. Mol Pharmacol (2004) 1.31
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands. Nat Chem Biol (2012) 1.31
Up-regulation of GLT-1 severely impairs LTD at mossy fibre--CA3 synapses. J Physiol (2009) 1.24
Genome scan for susceptibility loci for schizophrenia and bipolar disorder. Biol Psychiatry (2002) 1.23
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proc Natl Acad Sci U S A (2012) 1.22
A propofol binding site on mammalian GABAA receptors identified by photolabeling. Nat Chem Biol (2013) 1.21
The point mutation gamma 2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes. Eur J Pharmacol (2010) 1.20
Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function. EMBO J (2007) 1.20
Protein kinase C phosphorylation regulates membrane insertion of GABAA receptor subtypes that mediate tonic inhibition. J Biol Chem (2010) 1.19
'Deaf, mute and whispering' silent synapses: their role in synaptic plasticity. J Physiol (2004) 1.18
Nicotine activates immature "silent" connections in the developing hippocampus. Proc Natl Acad Sci U S A (2003) 1.17
Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat. J Neurochem (2003) 1.16
Low expression of Kv7/M channels facilitates intrinsic and network bursting in the developing rat hippocampus. J Physiol (2008) 1.15
Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure. Neuropharmacology (2010) 1.15
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. J Physiol (2006) 1.12
Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever! Front Cell Neurosci (2012) 1.12
Synthesis, in vitro affinity, and efficacy of a bis 8-ethynyl-4H-imidazo[1,5a]- [1,4]benzodiazepine analogue, the first bivalent alpha5 subtype selective BzR/GABA(A) antagonist. J Med Chem (2003) 1.11
The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs. J Neurosci (2011) 1.10
Deficits in spatial memory correlate with modified {gamma}-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus. Proc Natl Acad Sci U S A (2009) 1.09
Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption. J Neurochem (2002) 1.08
Gephyrin, the enigmatic organizer at GABAergic synapses. Front Cell Neurosci (2012) 1.07
PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats. Brain Res (2008) 1.05
GAT-1 regulates both tonic and phasic GABA(A) receptor-mediated inhibition in the cerebral cortex. J Neurochem (2008) 1.05
Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate. J Neurosci (2011) 1.05
GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus. J Neurosci (2006) 1.05
Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor. Mol Pharmacol (2012) 1.05
Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models. J Med Chem (2009) 1.05
Are GABAA receptors containing alpha5 subunits contributing to the sedative properties of benzodiazepine site agonists? Neuropsychopharmacology (2007) 1.03
Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats? Prog Neuropsychopharmacol Biol Psychiatry (2010) 1.03
Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. Front Synaptic Neurosci (2010) 1.01
Presynaptic source of quantal size variability at GABAergic synapses in rat hippocampal neurons in culture. Eur J Neurosci (2004) 1.01
Development of gamma-aminobutyric acidergic synapses in cultured hippocampal neurons. J Comp Neurol (2006) 1.01
Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin. J Biol Chem (2011) 1.00
Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus. J Physiol (2004) 1.00
Plasticity of GABAA receptors after ethanol pre-exposure in cultured hippocampal neurons. Mol Pharmacol (2010) 1.00
Declusterization of GABAA receptors affects the kinetic properties of GABAergic currents in cultured hippocampal neurons. J Biol Chem (2003) 1.00
Frequency-dependent shift from paired-pulse facilitation to paired-pulse depression at unitary CA3-CA3 synapses in the rat hippocampus. J Physiol (2002) 0.98
Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of alpha1-subunit-deficient mice. J Neurochem (2005) 0.98
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit. Biochem Pharmacol (2004) 0.97
Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus. Crit Rev Neurobiol (2006) 0.97
Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus. Proc Natl Acad Sci U S A (2007) 0.97
Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry. Mol Cell Proteomics (2012) 0.96
In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction. J Neurosci (2010) 0.95
The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology (2007) 0.94
Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem (2012) 0.93
Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals. J Neurochem (2010) 0.92
Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice. J Physiol (2006) 0.92
Gel-based mass spectrometric analysis of recombinant GABA(A) receptor subunits representing strongly hydrophobic transmembrane proteins. J Proteome Res (2008) 0.92
Increased expression of GABA(A) receptor beta-subunits in the hippocampus of patients with temporal lobe epilepsy. J Neuropathol Exp Neurol (2003) 0.91
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. J Med Chem (2008) 0.90
Aberrant GABA(A) receptor expression in the dentate gyrus of the epileptic mutant mouse stargazer. J Neurosci (2006) 0.90
Spontaneous recurrent network activity in organotypic rat hippocampal slices. Eur J Neurosci (2005) 0.90
The cell adhesion molecule neuroplastin-65 is a novel interaction partner of γ-aminobutyric acid type A receptors. J Biol Chem (2012) 0.89
Binge Drinking: In Search of its Molecular Target via the GABA(A) Receptor. Front Neurosci (2011) 0.89
Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures. J Biol Chem (2011) 0.89
In the developing rat hippocampus a tonic GABAA-mediated conductance selectively enhances the glutamatergic drive of principal cells. J Physiol (2007) 0.89
Modulation of GABA-mediated Synaptic Potentials by Glutamatergic Agonists in Neonatal CA3 Rat Hippocampal Neurons. Eur J Neurosci (1991) 0.89
An ID-like current that is downregulated by Ca2+ modulates information coding at CA3-CA3 synapses in the rat hippocampus. J Physiol (2003) 0.89
Regulation of GABA(A) receptor dynamics by interaction with purinergic P2X(2) receptors. J Biol Chem (2011) 0.89
Functional role of ambient GABA in refining neuronal circuits early in postnatal development. Front Neural Circuits (2013) 0.88
Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits. J Neurochem (2006) 0.88
Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains. Nat Protoc (2009) 0.88
Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in α4 Subunit Knockout Mice. Front Neurosci (2011) 0.88
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons. J Neurosci (2010) 0.88
Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors. Br J Pharmacol (2013) 0.87
Regulation of hippocampal inhibitory circuits by nicotinic acetylcholine receptors. J Physiol (2011) 0.87
PrPC controls via protein kinase A the direction of synaptic plasticity in the immature hippocampus. J Neurosci (2013) 0.87
Assembly of GABA(A) receptors (Review). Mol Membr Biol (2008) 0.87
"Presynaptic silence" may be golden. Neuropharmacology (2003) 0.86
Localization of GABA-A receptor alpha subunits on neurochemically distinct cell types in the rat locus coeruleus. Eur J Neurosci (2011) 0.86
Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells. Hippocampus (2007) 0.86
GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors. Front Cell Neurosci (2011) 0.86
Reactive oxygen species mediate the potentiating effects of ATP on GABAergic synaptic transmission in the immature hippocampus. J Biol Chem (2006) 0.84
Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus. Hippocampus (2007) 0.84