Published in Infect Immun on September 01, 2004
Misoprostol impairs female reproductive tract innate immunity against Clostridium sordellii. J Immunol (2008) 1.74
Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens. Infect Immun (2006) 1.62
Recombinant attenuated Salmonella enterica serovar typhimurium expressing the carboxy-terminal domain of alpha toxin from Clostridium perfringens induces protective responses against necrotic enteritis in chickens. Clin Vaccine Immunol (2008) 1.23
The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages. BMC Microbiol (2006) 1.09
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum. PLoS Pathog (2008) 1.07
Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease. Future Microbiol (2014) 1.07
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence. Infect Immun (2009) 1.02
Clostridium Perfringens Toxins Involved in Mammalian Veterinary Diseases. Open Toxinology J (2010) 1.01
Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. Antimicrob Agents Chemother (2007) 1.01
TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714. Infect Immun (2011) 0.95
Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens. PLoS Pathog (2012) 0.94
The role of anthrolysin O in gut epithelial barrier disruption during Bacillus anthracis infection. Biochem Biophys Res Commun (2010) 0.92
Identification and characterization of the first cholesterol-dependent cytolysins from Gram-negative bacteria. Infect Immun (2012) 0.89
The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells. Vet Res (2013) 0.88
Sensitive quantification of Clostridium perfringens in human feces by quantitative real-time PCR targeting alpha-toxin and enterotoxin genes. BMC Microbiol (2015) 0.83
EP4 and EP2 receptor activation of protein kinase A by prostaglandin E2 impairs macrophage phagocytosis of Clostridium sordellii. Am J Reprod Immunol (2013) 0.82
Engineered nanoparticles mimicking cell membranes for toxin neutralization. Adv Drug Deliv Rev (2015) 0.81
The influence of natural lipid asymmetry upon the conformation of a membrane-inserted protein (perfringolysin O). J Biol Chem (2014) 0.81
Lethal effects of Clostridium perfringens epsilon toxin are potentiated by alpha and perfringolysin-O toxins in a mouse model. Vet Microbiol (2007) 0.81
Comparative transcription analysis and toxin production of two fluoroquinolone-resistant mutants of Clostridium perfringens. BMC Microbiol (2013) 0.81
Enhanced production of phospholipase C and perfringolysin O (alpha and theta toxins) in a gatifloxacin-resistant strain of Clostridium perfringens. Antimicrob Agents Chemother (2007) 0.80
NanR, a Transcriptional Regulator That Binds to the Promoters of Genes Involved in Sialic Acid Metabolism in the Anaerobic Pathogen Clostridium perfringens. PLoS One (2015) 0.80
Perfringolysin O: The Underrated Clostridium perfringens Toxin? Toxins (Basel) (2015) 0.79
Clostridium perfringens α-Toxin Impairs Innate Immunity via Inhibition of Neutrophil Differentiation. Sci Rep (2016) 0.78
The rapid identification of Clostridium perfringens as the possible aetiology of a diarrhoeal outbreak using PCR. Epidemiol Infect (2007) 0.77
Transmembrane protein (perfringolysin o) association with ordered membrane domains (rafts) depends upon the raft-associating properties of protein-bound sterol. Biophys J (2013) 0.77
Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis. Sci Rep (2015) 0.77
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors. Microbiol Mol Biol Rev (2016) 0.76
Substrate uptake and subcellular compartmentation of anoxic cholesterol catabolism in Sterolibacterium denitrificans. J Biol Chem (2014) 0.76
Cloning of alpha-beta fusion gene from Clostridium perfringens and its expression. World J Gastroenterol (2006) 0.76
Insights from the draft genome into the pathogenicity of a clinical isolate of Elizabethkingia meningoseptica Em3. Stand Genomic Sci (2017) 0.75
Heat incubation inactivates streptococcal exotoxins and recombinant cholesterol-dependent cytolysins: suilysin, pneumolysin and streptolysin O. Curr Microbiol (2014) 0.75
Common themes in microbial pathogenicity revisited. Microbiol Mol Biol Rev (1997) 10.52
Mechanisms of phagocytosis in macrophages. Annu Rev Immunol (1999) 9.66
The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread. Infect Immun (1995) 4.02
Molecular genetics and pathogenesis of Clostridium perfringens. Microbiol Rev (1991) 3.81
Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils. Infect Immun (1974) 3.49
Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O. Infect Immun (1994) 3.27
Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Mol Microbiol (1995) 2.79
Mechanisms and management of antibiotic-associated diarrhea. Clin Infect Dis (1998) 2.75
Evidence that the enterotoxin gene can be episomal in Clostridium perfringens isolates associated with non-food-borne human gastrointestinal diseases. J Clin Microbiol (1998) 2.60
A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity. Science (2000) 2.51
The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. J Cell Biol (2002) 2.29
Nonoxidative antimicrobial reactions of leukocytes. Contemp Top Immunobiol (1984) 1.97
Capacity of listeriolysin O, streptolysin O, and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells. Infect Immun (1992) 1.91
Synergistic effects of alpha-toxin and perfringolysin O in Clostridium perfringens-mediated gas gangrene. Infect Immun (2001) 1.87
Expression from the Clostridium perfringens cpe promoter in C. perfringens and Bacillus subtilis. Infect Immun (1994) 1.68
Listeria monocytogenes mutants that fail to compartmentalize listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infect Immun (2003) 1.61
Beta-barrel pore-forming toxins: intriguing dimorphic proteins. Biochemistry (2001) 1.60
Effects of alpha and theta toxins from Clostridium perfringens on human polymorphonuclear leukocytes. J Infect Dis (1987) 1.56
Clostridial gas gangrene: evidence that alpha and theta toxins differentially modulate the immune response and induce acute tissue necrosis. J Infect Dis (1997) 1.52
The cholesterol-dependent cytolysins. Curr Top Microbiol Immunol (2001) 1.52
The role of clostridial toxins in the pathogenesis of gas gangrene. Clin Infect Dis (2002) 1.31
Use of genetically manipulated strains of Clostridium perfringens reveals that both alpha-toxin and theta-toxin are required for vascular leukostasis to occur in experimental gas gangrene. Infect Immun (1999) 1.24
Multiple effects on Clostridium perfringens binding, uptake and trafficking to lysosomes by inhibitors of macrophage phagocytosis receptors. Microbiology (2003) 1.20
The projection structure of perfringolysin O (Clostridium perfringens theta-toxin). FEBS Lett (1993) 1.13
Clostridial gas gangrene. I. Cellular and molecular mechanisms of microvascular dysfunction induced by exotoxins of Clostridium perfringens. J Infect Dis (2000) 1.12
Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: the roles of leukocytotoxicity and expression of CD11/CD18 adherence glycoprotein. FEMS Immunol Med Microbiol (1993) 1.11
Clostridial gas gangrene. II. Phospholipase C-induced activation of platelet gpIIbIIIa mediates vascular occlusion and myonecrosis in Clostridium perfringens gas gangrene. J Infect Dis (2000) 1.07
Role of alpha-toxin in Clostridium perfringens infection determined by using recombinants of C. perfringens and Bacillus subtilis. Infect Immun (1994) 0.96
Localization of adenovirus-encoded DNA replication proteins in the nucleus by immunogold electron microscopy. J Gen Virol (1990) 0.95
Interactions of polymorphonuclear leukocytes with anaerobic bacteria. Rev Infect Dis (1984) 0.93
The anaerobic pathogen Clostridium perfringens can escape the phagosome of macrophages under aerobic conditions. Cell Microbiol (2000) 0.90
Role of theta toxin, a sulfhydryl-activated cytolysin, in the pathogenesis of clostridial gas gangrene. Clin Infect Dis (1993) 0.88
The pathogenesis of clostridial myonecrosis. Int J Med Microbiol (2000) 0.83
Long-lived protective immunity to Listeria is conferred by immunization with particulate or soluble listerial antigen preparations coadministered with IL-12. Cell Immunol (1998) 0.82
Analysis of the phospholipase C gene of Clostridium perfringens KZ1340 isolated from Antarctic soil. Microbiol Immunol (1996) 0.78
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84
Type IV pili-dependent gliding motility in the Gram-positive pathogen Clostridium perfringens and other Clostridia. Mol Microbiol (2006) 1.96
Sporulation and enterotoxin (CPE) synthesis are controlled by the sporulation-specific sigma factors SigE and SigK in Clostridium perfringens. J Bacteriol (2009) 1.45
The CcpA protein is necessary for efficient sporulation and enterotoxin gene (cpe) regulation in Clostridium perfringens. J Bacteriol (2004) 1.38
Multiple effects on Clostridium perfringens binding, uptake and trafficking to lysosomes by inhibitors of macrophage phagocytosis receptors. Microbiology (2003) 1.20
Construction and characterization of a lactose-inducible promoter system for controlled gene expression in Clostridium perfringens. Appl Environ Microbiol (2010) 1.17
Type IV pili and the CcpA protein are needed for maximal biofilm formation by the gram-positive anaerobic pathogen Clostridium perfringens. Infect Immun (2008) 1.14
Factors contributing to heat resistance of Clostridium perfringens endospores. Appl Environ Microbiol (2008) 1.13
Synergy in polymicrobial infections in a mouse model of type 2 diabetes. Infect Immun (2005) 1.03
Use of a mariner-based transposon mutagenesis system to isolate Clostridium perfringens mutants deficient in gliding motility. J Bacteriol (2012) 0.86
EtfA catalyses the formation of dipicolinic acid in Clostridium perfringens. Mol Microbiol (2009) 0.82
The SpmA/B and DacF proteins of Clostridium perfringens play important roles in spore heat resistance. FEMS Microbiol Lett (2009) 0.80
The role of neutrophils and monocytic cells in controlling the initiation of Clostridium perfringens gas gangrene. FEMS Immunol Med Microbiol (2007) 0.79
Biochemistry and physiology of the β class carbonic anhydrase (Cpb) from Clostridium perfringens strain 13. J Bacteriol (2013) 0.78