Tadao Maeda

Author PubWeight™ 65.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver. J Biol Chem 2003 3.16
2 Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function. Nat Neurosci 2004 2.62
3 Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol 2013 2.53
4 Retinopathy in mice induced by disrupted all-trans-retinal clearance. J Biol Chem 2008 2.35
5 The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. J Biol Chem 2007 2.31
6 Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. J Biol Chem 2005 2.15
7 Recovery of visual functions in a mouse model of Leber congenital amaurosis. J Biol Chem 2002 2.11
8 Involvement of all-trans-retinal in acute light-induced retinopathy of mice. J Biol Chem 2009 2.01
9 Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle. Proc Natl Acad Sci U S A 2005 1.83
10 Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice. J Biol Chem 2004 1.64
11 Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation. J Biol Chem 2008 1.62
12 Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. J Biol Chem 2006 1.58
13 Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo. J Biol Chem 2005 1.58
14 Functional characterization of rhodopsin monomers and dimers in detergents. J Biol Chem 2004 1.57
15 Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration. J Biol Chem 2011 1.55
16 Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations. J Biol Chem 2011 1.55
17 Redundant and unique roles of retinol dehydrogenases in the mouse retina. Proc Natl Acad Sci U S A 2007 1.53
18 Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. J Biol Chem 2008 1.51
19 Primary amines protect against retinal degeneration in mouse models of retinopathies. Nat Chem Biol 2011 1.40
20 Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice. Mol Pharmacol 2006 1.38
21 Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina. J Biol Chem 2011 1.38
22 Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina. Invest Ophthalmol Vis Sci 2009 1.31
23 Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle. J Biol Chem 2005 1.29
24 Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal. J Biol Chem 2013 1.22
25 Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes. Nat Med 2010 1.18
26 Autophagy protects the retina from light-induced degeneration. J Biol Chem 2013 1.10
27 Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice. J Biol Chem 2011 1.08
28 Inflammatory priming predisposes mice to age-related retinal degeneration. J Clin Invest 2012 1.07
29 Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. J Clin Invest 2013 1.06
30 Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina. J Biol Chem 2008 1.04
31 Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice. Proc Natl Acad Sci U S A 2014 1.03
32 Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters. Biochemistry 2006 1.02
33 Palmitoylation stabilizes unliganded rod opsin. Proc Natl Acad Sci U S A 2010 0.99
34 Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal. Invest Ophthalmol Vis Sci 2006 0.97
35 Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest 2012 0.95
36 Modulation of molecular interactions and function by rhodopsin palmitylation. Biochemistry 2009 0.93
37 CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration. J Immunol 2014 0.92
38 Preservation of retinal morphology and functions in royal college surgeons rat by nilvadipine, a Ca(2+) antagonist. Invest Ophthalmol Vis Sci 2002 0.91
39 Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage. J Neurochem 2012 0.87
40 Evolutionarily conserved long intergenic non-coding RNAs in the eye. Hum Mol Genet 2013 0.85
41 Vitamin A derivatives as treatment options for retinal degenerative diseases. Nutrients 2013 0.84
42 Vaccination with recoverin, a cancer-associated retinopathy antigen, induces autoimmune retinal dysfunction and tumor cell regression in mice. Eur J Immunol 2002 0.82
43 Prolonged survival of the phosphorylated form of rhodopsin during dark adaptation of Royal College Surgeons rat. FEBS Lett 2003 0.81
44 A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids. Invest Ophthalmol Vis Sci 2012 0.80
45 Effects of cytotoxic T lymphocyte antigen 4 (CTLA4) signaling and locally applied steroid on retinal dysfunction by recoverin, cancer-associated retinopathy antigen. Mol Vis 2006 0.80
46 Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines. Biochem Biophys Res Commun 2003 0.79
47 Autoantibody against neuron-specific enolase found in glaucoma patients causes retinal dysfunction in vivo. Jpn J Ophthalmol 2002 0.78
48 [Molecular pathology of retinitis pigmentosa]. Nippon Ganka Gakkai Zasshi 2002 0.76
49 A high dietary intake of sodium glutamate as flavoring (ajinomoto) causes gross changes in retinal morphology and function. Exp Eye Res 2002 0.75
50 Supplementation with vitamin a derivatives to rescue vision in animal models of degenerative retinal diseases. Methods Mol Biol 2015 0.75