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1
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Effect on tumor cells of blocking survival response to glucose deprivation.
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J Natl Cancer Inst
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2004
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2.30
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2
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Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal.
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Cancer Sci
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2003
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1.86
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3
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Alteration in copy numbers of genes as a mechanism for acquired drug resistance.
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Cancer Res
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2004
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1.58
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4
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Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation.
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Cancer Res
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2009
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1.53
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5
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Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex.
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Cancer Res
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2004
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1.25
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6
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A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site.
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J Biol Chem
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2009
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1.01
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7
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IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.
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Clin Cancer Res
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2008
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0.99
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8
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
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J Biol Chem
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2007
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0.98
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9
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AP-1-Dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells.
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Oncol Res
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2010
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0.98
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10
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Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions.
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Cancer Sci
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2010
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0.96
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11
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Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation.
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Mol Cancer Ther
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2012
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0.92
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12
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Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
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J Cell Physiol
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2010
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0.91
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13
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Taxoids and abietanes from callus cultures of Taxus cuspidata.
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J Nat Prod
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2005
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0.90
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14
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Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin.
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Cancer Sci
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2009
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0.89
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15
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Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells.
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Int J Cancer
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2013
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0.88
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16
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Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex.
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Gastroenterology
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2007
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0.88
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17
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Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5.
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J Biol Chem
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2004
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0.88
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18
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Bioactive triterpene saponins from the roots of Phytolacca americana.
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J Nat Prod
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2008
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0.87
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19
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Biodistribution and ultrastructural localization of single-walled carbon nanohorns determined in vivo with embedded Gd2O3 labels.
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ACS Nano
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2009
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0.87
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20
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Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact.
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Am J Pathol
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2013
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0.86
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21
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Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
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Jpn J Cancer Res
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2002
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0.86
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22
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Prevention of carbon nanohorn agglomeration using a conjugate composed of comb-shaped polyethylene glycol and a peptide aptamer.
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Mol Pharm
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2009
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0.85
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23
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Compound C prevents the unfolded protein response during glucose deprivation through a mechanism independent of AMPK and BMP signaling.
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PLoS One
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2012
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0.85
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24
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Bioactive cardenolides from the stems and twigs of Nerium oleander.
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J Nat Prod
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2007
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0.84
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25
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SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin.
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Oncogene
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2002
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0.84
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26
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Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumor cells to topoisomerase II-directed drugs.
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Cancer Res
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2002
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0.83
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27
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Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator.
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J Cell Physiol
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2008
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0.81
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28
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Bioactive tetrahydrofuran lignans from Peperomia dindygulensis.
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J Nat Prod
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2005
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0.81
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29
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A new evaluation method for quantifying PI3K activity by HTRF assay.
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Biochem Biophys Res Commun
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2008
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0.81
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30
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Use of chemical genomics in assessment of the UPR.
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Methods Enzymol
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2011
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0.79
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31
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Production of biologically active taxoids by a callus culture of Taxus cuspidata.
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J Nat Prod
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2004
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0.78
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32
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Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.
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Cancer Sci
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2013
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0.78
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33
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Regulation of DNA topoisomerase IIalpha stability by the ECV ubiquitin ligase complex.
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Biochem Biophys Res Commun
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2009
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0.77
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34
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Bioactive polyketides from Peperomia duclouxii.
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J Nat Prod
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2007
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0.77
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35
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Bioactive dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii.
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J Nat Prod
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2006
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0.77
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36
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A 12-mm carcinoid tumor of the minor duodenal papilla with lymph node metastases.
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Jpn J Clin Oncol
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2012
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0.76
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37
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[Adaptive response of cancer cells to metabolic stress].
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Nihon Rinsho
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2014
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0.75
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38
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Synthesis and structure-activity relationships of taxuyunnanine C derivatives as multidrug resistance modulator in MDR cancer cells.
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Bioorg Med Chem Lett
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2007
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0.75
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39
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Bioactive lignans from Peperomia duclouxii.
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J Nat Prod
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2007
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0.75
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40
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A new taxoid from a callus culture of Taxus cuspidata as an MDR reversal agent.
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Chem Pharm Bull (Tokyo)
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2006
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0.75
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41
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Structure-activity relationships of some taxoids as multidrug resistance modulator.
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Bioorg Med Chem Lett
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2007
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0.75
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42
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Identification of chrysoplenetin from Vitex negundo as a potential cytotoxic agent against PANC-1 and a panel of 39 human cancer cell lines (JFCR-39).
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Phytother Res
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2011
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0.75
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