Published in N Engl J Med on September 02, 2004
Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343. J Clin Oncol (2013) 6.56
The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet (2008) 6.50
Nomogram to predict the benefit of radiation for older patients with breast cancer treated with conservative surgery. J Clin Oncol (2012) 2.85
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Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time? Breast Cancer Res Treat (2014) 2.18
Adjuvant hormonal therapy use among insured, low-income women with breast cancer. J Clin Oncol (2009) 2.14
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TARGIT-E(lderly)--prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer. BMC Cancer (2012) 0.86
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Adherence to adjuvant endocrine therapy in estrogen receptor-positive breast cancer patients with regular follow-up. Can J Surg (2014) 0.84
Breast radiotherapy after lumpectomy--no longer always necessary. N Engl J Med (2004) 0.83
Breast cancer therapy-associated cardiovascular disease. Nat Rev Clin Oncol (2015) 0.83
Recent developments in breast-conserving surgery for breast cancer patients. Langenbecks Arch Surg (2008) 0.82
Successful management of elderly breast cancer patients treated without radiotherapy. World J Surg Oncol (2007) 0.82
Elderly postmenopausal patients with breast cancer are at increased risk for distant recurrence: a tamoxifen exemestane adjuvant multinational study analysis. Oncologist (2012) 0.82
When are breast cancer patients old enough for the quitclaim of local control? Strahlenther Onkol (2012) 0.81
Semiparametric regression analysis for time-to-event marked endpoints in cancer studies. Biostatistics (2013) 0.81
Early-Stage Breast Cancer in the Elderly: Confronting an Old Clinical Problem. J Breast Cancer (2015) 0.80
Intraoperative radiotherapy in early stage breast cancer: potential indications and evidence to date. Br J Radiol (2015) 0.79
The complexity of microRNAs in human cancer. J Radiat Res (2016) 0.79
Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients. Int J Breast Cancer (2015) 0.79
The benefit of adjuvant radiotherapy after breast conserving surgery in older patients with low risk breast cancer- a meta-analysis of randomized trials. Radiat Oncol (2017) 0.77
Conservative management of breast cancer in the elderly in a developing country. World J Surg Oncol (2007) 0.77
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Radiation therapy in early-stage invasive breast cancer. Indian J Surg Oncol (2011) 0.77
Advances in managing breast cancer: a clinical update. F1000Prime Rep (2014) 0.76
Locoregional Recurrence and Survival Rates after Breast-Conserving Surgery and Hormonal Therapy in 70-Year-Old or Older Patients with Stage I or IIA Breast Carcinoma. Breast Care (Basel) (2013) 0.75
Adjuvant Endocrine Therapy in Breast Cancer: A Novel e-Health Approach in Optimizing Treatment for Seniors (OPTIMUM): A Two-Group Controlled Comparison Pilot Study. JMIR Res Protoc (2016) 0.75
Sorting out the survival impact of radiation therapy in early-stage invasive breast cancer. Ann Surg Oncol (2014) 0.75
Accelerated partial breast irradiation: a valid choice. Breast Cancer Res (2005) 0.75
Trends and controversies in multidisciplinary care of the patient with breast cancer. Curr Probl Surg (2016) 0.75
Proportion and clinical outcomes of postoperative radiotherapy omission after breast-conserving surgery in women with breast cancer. J Breast Cancer (2015) 0.75
Do all patients require radiotherapy after breast-conserving surgery? Cancers (Basel) (2010) 0.75
Early-Stage Breast Cancer in the Octogenarian: Tumor Characteristics, Treatment Choices, and Clinical Outcomes. Ann Surg Oncol (2016) 0.75
Accelerated partial breast irradiation compared with whole breast radiation therapy: a breast cancer cohort study measuring change in radiation side-effects severity and quality of life. Breast Cancer Res Treat (2017) 0.75
Optimal management of breast cancer in the elderly patient: current perspectives. Clin Interv Aging (2015) 0.75
Early breast cancer in the older woman. Clin Geriatr Med (2011) 0.75
Operation with less adjuvant therapy for elderly breast cancer. J Surg Res (2016) 0.75
Breast cancer (non-metastatic). BMJ Clin Evid (2007) 0.75
Trends in Local Therapy Utilization and Cost for Early-Stage Breast Cancer in Older Women: Implications for Payment and Policy Reform. Int J Radiat Oncol Biol Phys (2016) 0.75
Function-preserving surgery for breast cancer. Int J Clin Oncol (2006) 0.75
[Critical consideration of ipsilateral axillary recurrence after breast conservative surgery and the protective effect of whole breast radiotherapy]. Strahlenther Onkol (2017) 0.75
Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst (2005) 5.65
Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial. Lancet Oncol (2007) 5.39
Regional Nodal Irradiation in Early-Stage Breast Cancer. N Engl J Med (2015) 4.94
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res (2005) 4.61
Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J Clin Oncol (2002) 4.55
Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. J Clin Oncol (2010) 4.19
Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res (2002) 3.68
Trends in the utilization of brachytherapy in cervical cancer in the United States. Int J Radiat Oncol Biol Phys (2013) 3.56
Immunohistochemical detection using the new rabbit monoclonal antibody SP1 of estrogen receptor in breast cancer is superior to mouse monoclonal antibody 1D5 in predicting survival. J Clin Oncol (2006) 3.42
Factors associated with failure to publish large randomized trials presented at an oncology meeting. JAMA (2003) 3.36
Time to stop progesterone receptor testing in breast cancer management. J Clin Oncol (2004) 3.33
DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell (2005) 3.12
The impact of new chemotherapeutic and hormone agents on survival in a population-based cohort of women with metastatic breast cancer. Cancer (2007) 2.84
Prognostic gene signatures for non-small-cell lung cancer. Proc Natl Acad Sci U S A (2009) 2.84
An individual person data meta-analysis of preoperative magnetic resonance imaging and breast cancer recurrence. J Clin Oncol (2014) 2.83
Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res (2010) 2.79
Platinum-based versus non-platinum-based chemotherapy in advanced non-small-cell lung cancer: a meta-analysis of the published literature. J Clin Oncol (2005) 2.76
Effect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: a randomized, controlled clinical trial. J Clin Oncol (2002) 2.75
Comparative prognostic value of HPV16 E6 mRNA compared with in situ hybridization for human oropharyngeal squamous carcinoma. J Clin Oncol (2009) 2.74
Oral clodronate for adjuvant treatment of operable breast cancer (National Surgical Adjuvant Breast and Bowel Project protocol B-34): a multicentre, placebo-controlled, randomised trial. Lancet Oncol (2012) 2.65
Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type. Clin Cancer Res (2004) 2.51
Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer. J Clin Oncol (2006) 2.49
Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest (2009) 2.43
Impact on survival of time from definitive surgery to initiation of adjuvant chemotherapy for early-stage breast cancer. J Clin Oncol (2006) 2.38
Human epidermal growth factor receptor 2 overexpression as a prognostic factor in a large tissue microarray series of node-negative breast cancers. J Clin Oncol (2008) 2.38
Consensus conference on breast conservation. J Am Coll Surg (2006) 2.17
Insulin- and obesity-related variables in early-stage breast cancer: correlations and time course of prognostic associations. J Clin Oncol (2011) 2.15
Three-gene prognostic classifier for early-stage non small-cell lung cancer. J Clin Oncol (2007) 2.10
Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity-modulated radiotherapy for locoregional radiotherapy of left-sided breast cancer and internal mammary nodes. Int J Radiat Oncol Biol Phys (2010) 2.08
Chronic arm morbidity after curative breast cancer treatment: prevalence and impact on quality of life. J Clin Oncol (2002) 2.04
Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum Mol Genet (2009) 2.00
Health-related quality of life and psychosocial status in breast cancer prognosis: analysis of multiple variables. J Clin Oncol (2004) 1.98
Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers. Mod Pathol (2009) 1.91
Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proc Natl Acad Sci U S A (2011) 1.88
Histological features of melanoma sentinel lymph node metastases associated with status of the completion lymphadenectomy and rate of subsequent relapse. Ann Surg Oncol (2006) 1.83
Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol (2003) 1.83
Cardiac morbidity following modern treatment for Hodgkin lymphoma: supra-additive cardiotoxicity of doxorubicin and radiation therapy. Leuk Lymphoma (2008) 1.80
High insulin levels in newly diagnosed breast cancer patients reflect underlying insulin resistance and are associated with components of the insulin resistance syndrome. Breast Cancer Res Treat (2008) 1.78
Enumeration of circulating tumor cells in the blood of breast cancer patients after filtration enrichment: correlation with disease stage. Breast Cancer Res Treat (2004) 1.78
MicroRNA-301 mediates proliferation and invasion in human breast cancer. Cancer Res (2011) 1.75
Patients with t1 to t2 breast cancer with one to three positive nodes have higher local and regional recurrence risks compared with node-negative patients after breast-conserving surgery and whole-breast radiotherapy. Int J Radiat Oncol Biol Phys (2009) 1.70
Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study. Breast Cancer Res Treat (2012) 1.66
Gene expression profiling in cervical cancer: an exploration of intratumor heterogeneity. Clin Cancer Res (2006) 1.65
Intensive loading dose of trastuzumab achieves higher-than-steady-state serum concentrations and is well tolerated. J Clin Oncol (2009) 1.65
Ten-year outcomes in a population-based cohort of node-negative, lymphatic, and vascular invasion-negative early breast cancers without adjuvant systemic therapies. J Clin Oncol (2004) 1.61
Impact of routine pathology review on treatment for node-negative breast cancer. J Clin Oncol (2012) 1.59
Validation of a web-based predictive nomogram for ipsilateral breast tumor recurrence after breast conserving therapy. J Clin Oncol (2010) 1.59
Is mastectomy superior to breast-conserving treatment for young women? Int J Radiat Oncol Biol Phys (2007) 1.58
Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. J Thorac Oncol (2014) 1.55
The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer. Clin Cancer Res (2010) 1.51
Age-related variations in the use of axillary dissection: a survival analysis of 8038 women with T1-ST2 breast cancer. Int J Radiat Oncol Biol Phys (2002) 1.50
Is multibeam IMRT better than standard treatment for patients with left-sided breast cancer? Int J Radiat Oncol Biol Phys (2007) 1.49
Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast. Cancer (2005) 1.47
Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy. CMAJ (2004) 1.46
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Nat Immunol (2003) 1.45
Population-based outcomes for small cell lung cancer: impact of standard management policies in British Columbia. Lung Cancer (2004) 1.43
Tumor hypoxia predicts biochemical failure following radiotherapy for clinically localized prostate cancer. Clin Cancer Res (2012) 1.41
Incidence and prognostic impact of amenorrhea during adjuvant therapy in high-risk premenopausal breast cancer: analysis of a National Cancer Institute of Canada Clinical Trials Group Study--NCIC CTG MA.5. J Clin Oncol (2005) 1.40
Long-term outcome in localized extranodal mucosa-associated lymphoid tissue lymphomas treated with radiotherapy. Cancer (2010) 1.40
Does a three-field electron/minitangent photon technique offer dosimetric advantages to a multifield, photon-only technique for accelerated partial breast irradiation? Am J Clin Oncol (2010) 1.39
Expression and prognostic significance of kit, protein kinase B, and mitogen-activated protein kinase in patients with small cell lung cancer. Clin Cancer Res (2003) 1.38
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma. Cancer (2003) 1.38
Optimized application of penalized regression methods to diverse genomic data. Bioinformatics (2011) 1.37
Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. Mol Cancer (2010) 1.37
Selecting breast cancer patients with T1-T2 tumors and one to three positive axillary nodes at high postmastectomy locoregional recurrence risk for adjuvant radiotherapy. Int J Radiat Oncol Biol Phys (2005) 1.36
Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma. Cancer (2008) 1.35
Target volume delineation for partial breast radiotherapy planning: clinical characteristics associated with low interobserver concordance. Int J Radiat Oncol Biol Phys (2007) 1.34
Fractures following radiotherapy and limb-salvage surgery for lower extremity soft-tissue sarcomas. A comparison of high-dose and low-dose radiotherapy. J Bone Joint Surg Am (2005) 1.31
Understanding prognostic gene expression signatures in lung cancer. Clin Lung Cancer (2009) 1.30
Ascertaining prognosis for breast cancer in node-negative patients with innovative survival analysis. Breast J (2006) 1.29
The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers. Gynecol Oncol (2005) 1.27
Factors influencing risk of acute urinary retention after TRUS-guided permanent prostate seed implantation. Int J Radiat Oncol Biol Phys (2002) 1.26
The role of reexcision for positive margins in optimizing local disease control after breast-conserving surgery for cancer. Breast J (2006) 1.25
Evolving treatment strategies for inflammatory breast cancer: a population-based survival analysis. J Clin Oncol (2005) 1.24
Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy. Cancer (2012) 1.23
Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin Cancer Res (2004) 1.23
The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British Columbia and the M. D. Anderson Cancer Center. Int J Radiat Oncol Biol Phys (2007) 1.21
Individualized estimates of second cancer risks after contemporary radiation therapy for Hodgkin lymphoma. Cancer (2007) 1.20
A comparison of mantle versus involved-field radiotherapy for Hodgkin's lymphoma: reduction in normal tissue dose and second cancer risk. Radiat Oncol (2007) 1.20
Image-detected breast cancer: state of the art diagnosis and treatment. J Am Coll Surg (2005) 1.20
Reliability and validity testing of the Patient and Observer Scar Assessment Scale in evaluating linear scars after breast cancer surgery. Plast Reconstr Surg (2007) 1.19
Association of low tumor RNA integrity with response to chemotherapy in breast cancer patients. Breast Cancer Res Treat (2010) 1.18
Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas. Clin Cancer Res (2003) 1.17
Mammographic density and the risk of breast cancer recurrence after breast-conserving surgery. Cancer (2009) 1.17
Insulin-like growth factor binding proteins 1 and 3 and breast cancer outcomes. Breast Cancer Res Treat (2002) 1.16
Diet and breast cancer: evidence that extremes in diet are associated with poor survival. J Clin Oncol (2003) 1.15
Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker. Clin Cancer Res (2004) 1.15
Waist-to-hip ratio and breast cancer mortality. Am J Epidemiol (2003) 1.15
Is leptin a mediator of adverse prognostic effects of obesity in breast cancer? J Clin Oncol (2005) 1.14
Does intensive follow-up alter outcome in patients with advanced lung cancer? J Thorac Oncol (2007) 1.14
Stability and heterogeneity of expression profiles in lung cancer specimens harvested following surgical resection. Neoplasia (2005) 1.14
A population-based study of the fractionation of postlumpectomy breast radiation therapy. In regard to Ashworth et al. Int J Radiat Oncol Biol Phys (2013) 1.13
Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients. J Thorac Oncol (2014) 1.13
Tumor RNA disruption predicts survival benefit from breast cancer chemotherapy. Breast Cancer Res Treat (2015) 1.12