Published in Hum Mol Genet on September 02, 2004
Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proc Natl Acad Sci U S A (2006) 1.62
Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta (2009) 1.45
Accumulation and distribution of α-synuclein and ubiquitin in the CNS of Gaucher disease mouse models. Mol Genet Metab (2010) 1.35
Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules. Proc Natl Acad Sci U S A (2007) 1.29
Lysosomal lipid storage diseases. Cold Spring Harb Perspect Biol (2011) 1.26
Multi-system disorders of glycosphingolipid and ganglioside metabolism. J Lipid Res (2010) 1.22
Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice. Hum Mol Genet (2008) 0.99
Prosaposin deficiency and saposin B deficiency (activator-deficient metachromatic leukodystrophy): report on two patients detected by analysis of urinary sphingolipids and carrying novel PSAP gene mutations. Am J Med Genet A (2009) 0.98
Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse. Hum Mol Genet (2009) 0.97
The protective role of prosaposin and its receptors in the nervous system. Brain Res (2014) 0.94
Specific interaction between Sam68 and neuronal mRNAs: implication for the activity-dependent biosynthesis of elongation factor eEF1A. J Neurosci Res (2009) 0.89
The immunological functions of saposins. Adv Immunol (2010) 0.85
Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice. BMC Neurosci (2008) 0.83
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. PLoS Genet (2015) 0.82
The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion. Mol Cell Biol (2005) 0.79
Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice. Hum Mol Genet (2013) 0.79
My journey into the world of sphingolipids and sphingolipidoses. Proc Jpn Acad Ser B Phys Biol Sci (2012) 0.79
Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C. Biochem Biophys Res Commun (2015) 0.77
Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease. PLoS Genet (2016) 0.77
Lysosomal storage diseases: heterogeneous group of disorders. Bioimpacts (2013) 0.76
Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes. BMC Nephrol (2012) 0.76
Ceramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration? Int J Alzheimers Dis (2010) 0.76
Systematic analyses of free ceramide species and ceramide species comprising neutral glycosphingolipids by MALDI-TOF MS with high-energy CID. Glycoconj J (2011) 0.76
Regional expression of prosaposin in the wild-type and saposin D-deficient mouse brain detected by an anti-mouse prosaposin-specific antibody. Proc Jpn Acad Ser B Phys Biol Sci (2009) 0.76
A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline. Neurobiol Dis (2016) 0.75
Dietary phosphorus acutely impairs endothelial function. J Am Soc Nephrol (2009) 2.09
Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor. Clin Cancer Res (2013) 1.87
Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Pept Sci (2012) 1.71
Plasma adiponectin levels in newborns are higher than those in adults and positively correlated with birth weight. Clin Endocrinol (Oxf) (2004) 1.69
Ghrelin concentration in cord and neonatal blood: relation to fetal growth and energy balance. J Clin Endocrinol Metab (2003) 1.56
Molecular identity of periglomerular and short axon cells. J Neurosci (2010) 1.55
Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain. EMBO J (2011) 1.44
Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice. Diabetes (2011) 1.37
Analysis of maternal and neonatal factors that influence the nucleated and CD34+ cell yield for cord blood banking. Transfusion (2004) 1.27
Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults. J Biol Chem (2002) 1.27
Cytokinesis of neuroepithelial cells can divide their basal process before anaphase. EMBO J (2008) 1.26
RNA-binding protein HuD controls insulin translation. Mol Cell (2012) 1.25
Translational control of TOP2A influences doxorubicin efficacy. Mol Cell Biol (2011) 1.25
1 alpha,25-Dihydroxyvitamin D(3) is a preventive factor in the metastasis of lung cancer. Carcinogenesis (2004) 1.23
NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis. Antioxid Redox Signal (2006) 1.21
Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. EMBO J (2011) 1.21
Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs. Nucleic Acids Res (2011) 1.21
Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3. Proc Natl Acad Sci U S A (2006) 1.18
Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach. Free Radic Biol Med (2007) 1.16
Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma. J Cutan Pathol (2008) 1.16
Prostate stem cell antigen predicts tumour recurrence in superficial transitional cell carcinoma of the urinary bladder. BJU Int (2006) 1.16
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. Stroke (2007) 1.16
NADPH oxidase-derived reactive oxygen species are essential for differentiation of a mouse macrophage cell line (RAW264.7) into osteoclasts. J Med Invest (2009) 1.14
Expression of CD10 predicts tumor progression and unfavorable prognosis in malignant melanoma. J Am Acad Dermatol (2011) 1.13
Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract. Semin Immunopathol (2008) 1.11
Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor? PLoS One (2011) 1.11
Effects of lifestyle habits and eating meals together with the family on the prevalence of obesity among school children in Tokushima, Japan: a cross-sectional questionnaire-based survey. J Med Invest (2008) 1.10
Effect of Admission Glasgow Coma Scale Motor Score on Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients Receiving Therapeutic Hypothermia. Circ J (2015) 1.10
Stromal CD10 expression, as well as increased dermal macrophages and decreased Langerhans cells, are associated with malignant transformation of keratinocytes. J Cutan Pathol (2009) 1.07
Interferon-gamma activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells. Am J Physiol Cell Physiol (2005) 1.07
Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis. J Biol Chem (2004) 1.06
Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs. Front Mol Neurosci (2011) 1.06
Impact of therapeutic hypothermia in the treatment of patients with out-of-hospital cardiac arrest from the J-PULSE-HYPO study registry. Circ J (2011) 1.03
The expression of prostate stem cell antigen in human clear cell renal cell carcinoma: a quantitative reverse transcriptase-polymerase chain reaction analysis. BJU Int (2006) 1.02
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells. Mol Cancer Res (2012) 1.02
Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients. Int J Cancer (2014) 1.02
Delayed hepatothorax due to right-sided traumatic diaphragmatic rupture. Gen Thorac Cardiovasc Surg (2007) 1.01
Extracts of Momordica charantia suppress postprandial hyperglycemia in rats. J Nutr Sci Vitaminol (Tokyo) (2007) 1.00
Circadian intraocular pressure rhythm is generated by clock genes. Invest Ophthalmol Vis Sci (2006) 0.99
Molecular characterization of heat shock-like factor encoded on the human Y chromosome, and implications for male infertility. Biol Reprod (2004) 0.98
The N-terminal carbohydrate recognition domain of galectin-8 recognizes specific glycosphingolipids with high affinity. Glycobiology (2003) 0.98
Thiamine-responsive pyruvate dehydrogenase deficiency in two patients caused by a point mutation (F205L and L216F) within the thiamine pyrophosphate binding region. Biochim Biophys Acta (2002) 0.98
Bezafibrate, a peroxisome proliferator-activated receptors agonist, decreases body temperature and enhances electroencephalogram delta-oscillation during sleep in mice. Endocrinology (2008) 0.97
Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix. Biochim Biophys Acta (2003) 0.97
Evaluation of counterions for electrospray ionization mass spectral analysis of a highly sulfated carbohydrate, sucrose octasulfate. Anal Chem (2003) 0.96
Growth inhibition by miR-519 via multiple p21-inducing pathways. Mol Cell Biol (2012) 0.95
Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation. Mol Pharmacol (2004) 0.94
Receptor activator of nuclear factor-kappaB ligand-induced mouse osteoclast differentiation is associated with switching between NADPH oxidase homologues. Free Radic Biol Med (2009) 0.94
Impact of splenectomy in patients with liver cirrhosis: Results from 18 patients in a single center experience. Hepatol Res (2010) 0.93
Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats. J Nutr (2007) 0.93
Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites. Chem Res Toxicol (2008) 0.92
Transforming growth factor-beta1 stimulates collagen matrix remodeling through increased adhesive and contractive potential by human renal fibroblasts. Biochim Biophys Acta (2004) 0.92
Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways. Am J Physiol Endocrinol Metab (2009) 0.92
The function of sphingolipids in the nervous system: lessons learnt from mouse models of specific sphingolipid activator protein deficiencies. J Neurochem (2007) 0.91
Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. J Biol Chem (2011) 0.91
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic Biol Med (2008) 0.91
Short-latency somatosensory evoked potentials in infantile autism: evidence of hyperactivity in the right primary somatosensory area. Dev Med Child Neurol (2007) 0.91
Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men. Metabolism (2007) 0.90
Glomerular distribution and gelatinolytic activity of matrix metalloproteinases in human glomerulonephritis. Nephrol Dial Transplant (2002) 0.90
Serial brain imaging analysis of stroke-like episodes in MELAS. Brain Dev (2008) 0.90
Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice. J Bone Miner Metab (2009) 0.89
Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet. J Nutr Biochem (2011) 0.89
Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts. Bone (2007) 0.89
Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery. Hypertension (2008) 0.89
Quercetin prevents unloading-derived disused muscle atrophy by attenuating the induction of ubiquitin ligases in tail-suspension mice. J Nat Prod (2010) 0.89
Mechanical thrombolysis for treatment of acute sinus thrombosis--case report. Neurol Med Chir (Tokyo) (2005) 0.88
Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly. Biosci Biotechnol Biochem (2010) 0.88
Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb. J Comp Neurol (2014) 0.87
Expression analysis of a mouse orthologue of HSFY, a candidate for the azoospermic factor on the human Y chromosome. J Med Invest (2006) 0.87
Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction. J Biol Chem (2003) 0.87
Genetic diversity of Theileria orientalis in tick vectors detected in Hokkaido and Okinawa, Japan. Infect Genet Evol (2012) 0.87
Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion. Metabolism (2004) 0.86
Gene expression profiling in peripheral blood leukocytes as a new approach for assessment of human stress response. J Med Invest (2005) 0.86
Effects of xylitol on metabolic parameters and visceral fat accumulation. J Clin Biochem Nutr (2011) 0.86
Fibrillary glomerulonephritis associated with essential thrombocytosis. Clin Exp Nephrol (2003) 0.86
A case of acute encephalitis with refractory, repetitive partial seizures, presenting autoantibody to glutamate receptor Gluepsilon2. Brain Dev (2005) 0.86
Chemical and apoptotic properties of hydroxy-ceramides containing long-chain bases with unusual alkyl chain lengths. J Biochem (2008) 0.86
Concordant over-expression of transcription factor Sp1 and vascular endothelial growth factor in extramammary Paget's disease. Int J Dermatol (2008) 0.86
Clinically relevant concentrations of propofol have no effect on adenosine triphosphate-sensitive potassium channels in rat ventricular myocytes. Anesthesiology (2002) 0.86
Regulation of renal sodium-dependent phosphate co-transporter genes (Npt2a and Npt2c) by all-trans-retinoic acid and its receptors. Biochem J (2010) 0.86
Dose-dependent effects of barley cooked with white rice on postprandial glucose and desacyl ghrelin levels. J Clin Biochem Nutr (2009) 0.85
Role of membrane microdomains in PTH-mediated down-regulation of NaPi-IIa in opossum kidney cells. Kidney Int (2005) 0.85
Significance of cyclin D1-, product of retinoblastoma (pRb), p53, p63 and p73 expression in eccrine poroma and eccrine porocarcinoma. J Dermatol Sci (2009) 0.85
Metastatic growth of lung cancer cells is extremely reduced in Vitamin D receptor knockout mice. J Steroid Biochem Mol Biol (2004) 0.85
Single-strand conformation polymorphism analysis of the FMR1 gene in autistic and mentally retarded children in Japan. J Med Invest (2004) 0.85
Are lifetime prevalence of impetigo, molluscum and herpes infection really increased in children having atopic dermatitis? J Dermatol Sci (2010) 0.85
Molecular mechanisms of the inhibitory effects of propofol and thiamylal on sarcolemmal adenosine triphosphate-sensitive potassium channels. Anesthesiology (2004) 0.85
Localization of enolase in synaptic plasma membrane as an alphagamma heterodimer in rat brain. Neurosci Res (2004) 0.84
Natto and viscous vegetables in a Japanese style meal suppress postprandial glucose and insulin responses. Asia Pac J Clin Nutr (2008) 0.84
Pathophysiology of the transient temporal lobe lesion in a patient with Menkes disease. Pediatr Int (2008) 0.84
Neurological benefit of therapeutic hypothermia following return of spontaneous circulation for out-of-hospital non-shockable cardiac arrest. Circ J (2012) 0.84
Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation. J Anesth (2008) 0.83
Expression of matrix metalloproteinase-9 in thrombin-induced brain edema formation in rats. J Stroke Cerebrovasc Dis (2007) 0.83
Hematopoietic cell transplantation ameliorates clinical phenotype and progression of the CNS pathology in the mouse model of late onset Krabbe disease. J Neuropathol Exp Neurol (2005) 0.83
PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells. J Cell Physiol (2004) 0.83
Diurnal amplitudes of arterial pressure and heart rate are dampened in Clock mutant mice and adrenalectomized mice. Endocrinology (2008) 0.83
Dietary phosphate restriction ameliorates endothelial dysfunction in adenine-induced kidney disease rats. J Clin Biochem Nutr (2012) 0.83