Published in J Biol Chem on September 07, 2004
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PTEN in liver diseases and cancer. World J Gastroenterol (2010) 0.97
Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc. J Biol Chem (2010) 0.96
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NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN. J Cell Biochem (2007) 0.93
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Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses. Cell Death Differ (2012) 0.92
Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification. J Biol Chem (2011) 0.90
Involvement of GLTSCR2 in the DNA Damage Response. Am J Pathol (2011) 0.90
Nucleolar localization of GLTSCR2/PICT-1 is mediated by multiple unique nucleolar localization sequences. PLoS One (2012) 0.84
GLTSCR2/PICT1 links mitochondrial stress and Myc signaling. Proc Natl Acad Sci U S A (2014) 0.83
GLTSCR2/PICT-1, a putative tumor suppressor gene product, induces the nucleolar targeting of the Kaposi's sarcoma-associated herpesvirus KS-Bcl-2 protein. J Virol (2009) 0.83
Merlin: the wizard requires protein stability to function as a tumor suppressor. Biochim Biophys Acta (2012) 0.82
Interdiction of sphingolipid metabolism to improve standard cancer therapies. Adv Cancer Res (2013) 0.81
PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression. Br J Cancer (2013) 0.81
Exosome-mediated delivery of the intrinsic C-terminus domain of PTEN protects it from proteasomal degradation and ablates tumorigenesis. Mol Ther (2014) 0.80
Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis. Nat Cell Biol (2015) 0.80
UVA induces lesions resembling seborrheic keratoses in mice with keratinocyte-specific PTEN downregulation. J Invest Dermatol (2011) 0.80
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Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein. J Biol Chem (2014) 0.76
Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs. Intrinsically Disord Proteins (2014) 0.75
PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway. Oncotarget (2016) 0.75
Genes and proteins differentially expressed during in vitro malignant transformation of bovine pancreatic duct cells. Neoplasia (2007) 0.75
PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway. Oncotarget (2016) 0.75
The nucleolar protein GLTSCR2 is required for efficient viral replication. Sci Rep (2016) 0.75
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat Cell Biol (2006) 3.19
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science (2009) 2.23
Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis. Sci Signal (2012) 1.86
Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. J Biol Chem (2005) 1.63
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11. Nat Med (2011) 1.52
Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. J Clin Invest (2008) 1.33
The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration. Sci Signal (2009) 1.29
RalA functions as an indispensable signal mediator for the nutrient-sensing system. J Biol Chem (2008) 1.28
Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}. J Exp Med (2005) 1.22
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. Mol Biol Cell (2006) 1.21
Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol (2006) 1.12
Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons. J Neurochem (2004) 1.06
Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis. EMBO J (2007) 1.05
S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN. Biochem Biophys Res Commun (2007) 1.04
Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling. J Biol Chem (2002) 1.04
Regulation of Bin1 SH3 domain binding by phosphoinositides. EMBO J (2004) 1.03
Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation. Proc Natl Acad Sci U S A (2008) 1.02
Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain. J Biol Chem (2010) 1.01
A new PICTure of nucleolar stress. Cancer Sci (2012) 0.98
Capturing the mammalian Hippo: elucidating its role in cancer. Cancer Sci (2013) 0.97
The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition. Dev Biol (2010) 0.97
Requirement of autophosphorylated tyrosine 992 of EGF receptor and its docking protein phospholipase C gamma 1 for membrane ruffle formation. FEBS Lett (2003) 0.95
NMDA receptor-mediated PIP5K activation to produce PI(4,5)P₂ is essential for AMPA receptor endocytosis during LTD. Neuron (2012) 0.94
RhoA-mediated Phospholipase D1 signaling is not required for the formation of stress fibers and focal adhesions. Cell Signal (2005) 0.93
Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. PLoS One (2013) 0.92
A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem (2003) 0.92
Molecular mechanisms of N-formyl-methionyl-leucyl-phenylalanine-induced superoxide generation and degranulation in mouse neutrophils: phospholipase D is dispensable. Mol Cell Biol (2012) 0.89
Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. J Neurosci (2005) 0.89
Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation. J Biol Chem (2013) 0.89
Essential role for phospholipase D2 activation downstream of ERK MAP kinase in nerve growth factor-stimulated neurite outgrowth from PC12 cells. J Biol Chem (2004) 0.88
The scaffold protein JIP3 functions as a downstream effector of the small GTPase ARF6 to regulate neurite morphogenesis of cortical neurons. FEBS Lett (2010) 0.87
Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation. J Biol Chem (2010) 0.87
Production of research-grade antibody by in vivo electroporation of DNA-encoding target protein. Anal Biochem (2005) 0.87
Regulation of PIP5K activity by Arf6 and its physiological significance. J Cell Physiol (2011) 0.87
Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia (2004) 0.86
Phosphatidylinositol 4-phosphate 5-kinase α facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) location. J Biol Chem (2013) 0.86
Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis. EMBO J (2012) 0.85
Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. PLoS Genet (2012) 0.84
Tissue- and development-dependent expression of the small GTPase Arf6 in mice. Dev Dyn (2010) 0.84
Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release. J Biol Chem (2002) 0.84
The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation. FEBS Lett (2005) 0.84
SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals. PLoS One (2010) 0.84
Activation mechanisms of PIP5K isozymes by the small GTPase ARF6. Adv Enzyme Regul (2009) 0.83
Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN. FEBS Lett (2004) 0.82
A naphthoquinone derivative, shikonin, has insulin-like actions by inhibiting both phosphatase and tensin homolog deleted on chromosome 10 and tyrosine phosphatases. Mol Pharmacol (2006) 0.81
Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing. PLoS One (2013) 0.81
Role of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cells. Mol Biol Cell (2009) 0.80
Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice. Diabetes (2011) 0.79
Phosphatidylinositol 4-phosphate 5-kinase is indispensable for mouse spermatogenesis. Biol Reprod (2012) 0.79
Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6. BMC Cell Biol (2009) 0.77
Phospholipase D2 activation by p38 MAP kinase is involved in neurite outgrowth. Biochem Biophys Res Commun (2011) 0.76
Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein. J Biol Chem (2014) 0.76
Physiological functions of the small GTPase Arf6 in the nervous system. Small GTPases (2015) 0.75
[Effective gene therapy for neoplasms utilizing the prognostic factors]. Nihon Jibiinkoka Gakkai Kaiho (2002) 0.75
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An improved method for cell-to-cell transmission of infectious prion. Biochem Biophys Res Commun (2010) 0.75
Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons. Neurosci Lett (2013) 0.75
[Physiological significance of phosphatidylinositol 4-phosphate 5-kinase in mammals]. Seikagaku (2013) 0.75
Garcinia vilersiana bark extract activates the Nrf2/HO-1 signaling pathway in RAW264.7 cells. J Toxicol Sci (2013) 0.75