Published in Mol Vis on August 30, 2004
Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites. Anal Chem (2007) 1.43
A typology of photoreceptor gene expression patterns in the mouse. Proc Natl Acad Sci U S A (2007) 1.37
Disease gene candidates revealed by expression profiling of retinal ganglion cell development. J Neurosci (2007) 1.08
Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment. Hum Genet (2009) 0.95
Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol (2009) 0.89
Lack of Cyp1b1 promotes the proliferative and migratory phenotype of perivascular supporting cells. Lab Invest (2013) 0.88
A novel methodology for enhanced and consistent heterologous expression of unmodified human cytochrome P450 1B1 (CYP1B1). PLoS One (2014) 0.87
Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. Mol Cell Biol (2013) 0.86
Identification of novel stem cell markers using gap analysis of gene expression data. Genome Biol (2007) 0.84
Identification of estrogen target genes during zebrafish embryonic development through transcriptomic analysis. PLoS One (2013) 0.83
Cytochrome P450 1B1 and Primary Congenital Glaucoma. J Ophthalmic Vis Res (2015) 0.80
Stimulation of mouse Cyp1b1 during adipogenesis: characterization of promoter activation by the transcription factor Pax6. Arch Biochem Biophys (2013) 0.78
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol (2016) 0.77
Ultrastructural abnormalities of the trabecular meshwork extracellular matrix in Cyp1b1-deficient mice. Vet Pathol (2014) 0.76
Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. J Ocul Biol (2016) 0.75
Analysis of CYP1B1 in pediatric and adult glaucoma and other ocular phenotypes. Mol Vis (2016) 0.75
Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα. Arch Biochem Biophys (2016) 0.75
Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science (2002) 6.53
Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1. Hum Mol Genet (2005) 3.56
The many roles of cytochrome b5. Pharmacol Ther (2003) 2.69
A new locus (GLC1H) for adult-onset primary open-angle glaucoma maps to the 2p15-p16 region. Arch Ophthalmol (2007) 1.74
Molecular genetics of primary congenital glaucoma in Brazil. Invest Ophthalmol Vis Sci (2002) 1.54
Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma. Mol Vis (2008) 1.51
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch Biochem Biophys (2005) 1.47
Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites. Anal Chem (2007) 1.43
Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1. Drug Metab Dispos (2004) 1.43
CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes. J Mol Diagn (2007) 1.41
Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene. Invest Ophthalmol Vis Sci (2005) 1.22
Genetics and biochemistry of primary congenital glaucoma. Ophthalmol Clin North Am (2003) 1.17
Biochemical applications of ultrathin films of enzymes, polyions and DNA. Chem Commun (Camb) (2007) 1.15
Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films. J Am Chem Soc (2003) 1.15
Optineurin in primary open angle glaucoma. Ophthalmol Clin North Am (2003) 1.15
Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s. J Am Chem Soc (2011) 1.14
Optimization of electrochemical and peroxide-driven oxidation of styrene with ultrathin polyion films containing cytochrome P450cam and myoglobin. Chembiochem (2003) 1.12
Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine. Chem Commun (Camb) (2007) 1.11
Protein film electrochemistry of microsomes genetically enriched in human cytochrome p450 monooxygenases. J Am Chem Soc (2005) 1.10
Synergistic metabolic toxicity screening using microsome/DNA electrochemiluminescent arrays and nanoreactors. Anal Chem (2008) 1.08
Evaluating enzymes that generate genotoxic benzo[a]pyrene metabolites using sensor arrays. Anal Chem (2005) 1.04
Cyp1b1 protein in the mouse eye during development: an immunohistochemical study. Drug Metab Dispos (2007) 1.01
Toxicity screening using biosensors that measure DNA damage. Curr Opin Drug Discov Devel (2007) 0.99
Genotype and phenotype correlations in congenital glaucoma: CYP1B1 mutations, goniodysgenesis, and clinical characteristics. Am J Ophthalmol (2006) 0.99
Differences in metabolite-mediated toxicity of tamoxifen in rodents versus humans elucidated with DNA/microsome electro-optical arrays and nanoreactors. Chem Res Toxicol (2009) 0.97
Enzyme-DNA biocolloids for DNA adduct and reactive metabolite detection by chromatography-mass spectrometry. Anal Chem (2008) 0.96
Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations observed in individuals with primary congenital glaucoma. Pharmacogenet Genomics (2008) 0.96
The role of the WDR36 gene on chromosome 5q22.1 in a large family with primary open-angle glaucoma mapped to this region. Arch Ophthalmol (2006) 0.95
Bioelectronic delivery of electrons to cytochrome P450 enzymes. J Phys Chem B (2011) 0.95
Molecular cloning, genomic structure, and protein characterization of mouse optineurin. Genomics (2005) 0.95
Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format. Anal Chem (2009) 0.94
Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions. Biophys Chem (2003) 0.93
LTBP2 gene analysis in the GLC3C-linked family and 94 CYP1B1-negative cases with primary congenital glaucoma. Ophthalmic Genet (2012) 0.92
High-throughput metabolic toxicity screening using magnetic biocolloid reactors and LC-MS/MS. Anal Chem (2010) 0.91
Xenobiotic-metabolizing cytochromes P450 in ontogeny: evolving perspective. Drug Metab Rev (2004) 0.91
Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes. J Neurochem (2011) 0.91
Electrochemiluminescent/voltammetric toxicity screening sensor using enzyme-generated DNA damage. Biosens Bioelectron (2007) 0.90
Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry. Annu Rev Anal Chem (Palo Alto Calif) (2012) 0.90
Control of electrochemical and ferryloxy formation kinetics of cyt P450s in polyion films by heme iron spin state and secondary structure. J Am Chem Soc (2009) 0.89
Molecular cloning and expression profiling of optineurin in the rhesus monkey. Invest Ophthalmol Vis Sci (2005) 0.89
Evaluation of electrochemiluminescent metabolic toxicity screening arrays using a multiple compound set. Anal Chem (2011) 0.89
Defining the pathogenicity of optineurin in juvenile open-angle glaucoma. Invest Ophthalmol Vis Sci (2004) 0.88
Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase. Anal Chem (2008) 0.88
Genotype and phenotype correlations in congenital glaucoma. Trans Am Ophthalmol Soc (2006) 0.88
Spectral analyses of cytochromes P450. Methods Mol Biol (2006) 0.87
Screening reactive metabolites bioactivated by multiple enzyme pathways using a multiplexed microfluidic system. Analyst (2012) 0.86
Thin multicomponent films for functional enzyme devices and bioreactor particles. Soft Matter (2014) 0.84
Analysis of rare variants and common haplotypes in the optineurin gene in Swedish glaucoma cases. Ophthalmic Genet (2005) 0.82
Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA. Chem Commun (Camb) (2009) 0.82
Lymphoedema-distichiasis and FOXC2: unreported mutations, de novo mutation estimate, families without coding mutations. Hum Genet (2005) 0.82
Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays. Mol Biosyst (2008) 0.80
Accurate DNA fragment sizing by capillary electrophoresis with laser-induced fluorescence array for detection of sequence specificity of DNA damage. Anal Chem (2008) 0.80
The use of microarray technology in deciphering the cause of genetic eye diseases: LOXL1 and exfoliation syndrome. Am J Ophthalmol (2008) 0.80
Genotoxicity-related chemistry of human metabolites of benzo[ghi]perylene (B[ghi]P) investigated using electro-optical arrays and DNA/microsome biocolloid reactors with LC-MS/MS. Chem Res Toxicol (2013) 0.79
Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines. Chem Commun (Camb) (2008) 0.79
Embryonic expression of the optineurin (glaucoma) gene in different stages of mouse development. Mol Vis (2007) 0.79
Characterizing metabolic inhibition using electrochemical enzyme/DNA biosensors. Anal Chem (2009) 0.78
Genetic screening of leber congenital amaurosis in a large consanguineous Iranian family. Ophthalmic Genet (2007) 0.77
Co-variation of STI1 and WDR36/UTP21 alters cell proliferation in a glaucoma model. Mol Vis (2011) 0.76
Primary non-syndromic lymphoedema (Meige disease) is not caused by mutations in FOXC2. Eur J Hum Genet (2008) 0.75
Measurement of cytochrome P-450. Curr Protoc Toxicol (2002) 0.75