PubRank

John B Schenkman

Author PubWeight™ 35.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch Biochem Biophys 2005 1.47
2 Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites. Anal Chem 2007 1.43
3 Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1. Drug Metab Dispos 2004 1.43
4 Genetics and biochemistry of primary congenital glaucoma. Ophthalmol Clin North Am 2003 1.17
5 Biochemical applications of ultrathin films of enzymes, polyions and DNA. Chem Commun (Camb) 2007 1.15
6 Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films. J Am Chem Soc 2003 1.15
7 Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s. J Am Chem Soc 2011 1.14
8 Optimization of electrochemical and peroxide-driven oxidation of styrene with ultrathin polyion films containing cytochrome P450cam and myoglobin. Chembiochem 2003 1.12
9 Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine. Chem Commun (Camb) 2007 1.11
10 Protein film electrochemistry of microsomes genetically enriched in human cytochrome p450 monooxygenases. J Am Chem Soc 2005 1.10
11 Synergistic metabolic toxicity screening using microsome/DNA electrochemiluminescent arrays and nanoreactors. Anal Chem 2008 1.08
12 Evaluating enzymes that generate genotoxic benzo[a]pyrene metabolites using sensor arrays. Anal Chem 2005 1.04
13 Cyp1b1 protein in the mouse eye during development: an immunohistochemical study. Drug Metab Dispos 2007 1.01
14 Toxicity screening using biosensors that measure DNA damage. Curr Opin Drug Discov Devel 2007 0.99
15 Differences in metabolite-mediated toxicity of tamoxifen in rodents versus humans elucidated with DNA/microsome electro-optical arrays and nanoreactors. Chem Res Toxicol 2009 0.97
16 Expression of cytochrome P4501b1 (Cyp1b1) during early murine development. Mol Vis 2004 0.97
17 Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations observed in individuals with primary congenital glaucoma. Pharmacogenet Genomics 2008 0.96
18 Enzyme-DNA biocolloids for DNA adduct and reactive metabolite detection by chromatography-mass spectrometry. Anal Chem 2008 0.96
19 Bioelectronic delivery of electrons to cytochrome P450 enzymes. J Phys Chem B 2011 0.95
20 Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format. Anal Chem 2009 0.94
21 Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions. Biophys Chem 2003 0.93
22 High-throughput metabolic toxicity screening using magnetic biocolloid reactors and LC-MS/MS. Anal Chem 2010 0.91
23 Xenobiotic-metabolizing cytochromes P450 in ontogeny: evolving perspective. Drug Metab Rev 2004 0.91
24 Electrochemiluminescent/voltammetric toxicity screening sensor using enzyme-generated DNA damage. Biosens Bioelectron 2007 0.90
25 Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry. Annu Rev Anal Chem (Palo Alto Calif) 2012 0.90
26 Evaluation of electrochemiluminescent metabolic toxicity screening arrays using a multiple compound set. Anal Chem 2011 0.89
27 Control of electrochemical and ferryloxy formation kinetics of cyt P450s in polyion films by heme iron spin state and secondary structure. J Am Chem Soc 2009 0.89
28 Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase. Anal Chem 2008 0.88
29 Screening reactive metabolites bioactivated by multiple enzyme pathways using a multiplexed microfluidic system. Analyst 2012 0.86
30 Thin multicomponent films for functional enzyme devices and bioreactor particles. Soft Matter 2014 0.84
31 Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA. Chem Commun (Camb) 2009 0.82
32 Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays. Mol Biosyst 2008 0.80
33 Accurate DNA fragment sizing by capillary electrophoresis with laser-induced fluorescence array for detection of sequence specificity of DNA damage. Anal Chem 2008 0.80
34 Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines. Chem Commun (Camb) 2008 0.79
35 Genotoxicity-related chemistry of human metabolites of benzo[ghi]perylene (B[ghi]P) investigated using electro-optical arrays and DNA/microsome biocolloid reactors with LC-MS/MS. Chem Res Toxicol 2013 0.79
36 Characterizing metabolic inhibition using electrochemical enzyme/DNA biosensors. Anal Chem 2009 0.78