Published in Circulation on September 14, 2004
Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis. Circulation (2012) 4.56
Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest (2005) 4.25
Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis. Arch Neurol (2010) 4.03
Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions. Circ Res (2013) 3.56
Transendocardial mesenchymal stem cells and mononuclear bone marrow cells for ischemic cardiomyopathy: the TAC-HFT randomized trial. JAMA (2014) 2.19
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93
Stem cell therapy is proarrhythmic. Circulation (2009) 1.83
In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium. Arterioscler Thromb Vasc Biol (2011) 1.80
Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. Eur Heart J (2011) 1.80
Endothelial progenitor cells in neovascularization of infarcted myocardium. J Mol Cell Cardiol (2008) 1.69
Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions. Blood (2006) 1.63
The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Prog Neurobiol (2011) 1.61
Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction. Stem Cells (2008) 1.58
Cell-based therapies and imaging in cardiology. Eur J Nucl Med Mol Imaging (2005) 1.36
Bone marrow stem cell mobilization in stroke: a 'bonehead' may be good after all! Leukemia (2011) 1.31
Imaging: guiding the clinical translation of cardiac stem cell therapy. Circ Res (2011) 1.30
Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation? Langenbecks Arch Surg (2011) 1.26
Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action. Circ Res (2010) 1.26
Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J Clin Invest (2008) 1.20
Stem cells in the heart: what's the buzz all about? Part 2: Arrhythmic risks and clinical studies. Heart Rhythm (2008) 1.19
Stem cell therapy: MRI guidance and monitoring. J Magn Reson Imaging (2008) 1.17
Cardiac repair and regeneration: the Rubik's cube of cell therapy for heart disease. Dis Model Mech (2009) 1.16
Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block. Sci Transl Med (2014) 1.12
Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. Anat Rec A Discov Mol Cell Evol Biol (2006) 1.11
Mesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment. Cell Commun Signal (2012) 1.06
Multicenter randomized trial of cell therapy in cardiopathies - MiHeart Study. Trials (2007) 1.01
Cell-based therapy for heart disease: a clinically oriented perspective. Mol Ther (2009) 1.00
Current perspectives on imaging cardiac stem cell therapy. J Nucl Med (2010) 1.00
Atherosclerosis as a disease of failed endogenous repair. Front Biosci (2008) 1.00
Getting to the heart of myocardial stem cells and cell therapy. Circulation (2011) 0.95
Cell delivery and tracking in post-myocardial infarction cardiac stem cell therapy: an introduction for clinical researchers. Heart Fail Rev (2010) 0.93
Tracking of stem cells in vivo for cardiovascular applications. J Cardiovasc Magn Reson (2014) 0.92
Acute and chronic effects of exercise on circulating endothelial progenitor cells in healthy and diseased patients. Clin Res Cardiol (2012) 0.91
Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure. J Cardiothorac Surg (2006) 0.90
A comparison of the reparative and angiogenic properties of mesenchymal stem cells derived from the bone marrow of BALB/c and C57/BL6 mice in a model of limb ischemia. Stem Cell Res Ther (2013) 0.89
Current stem cell delivery methods for myocardial repair. Biomed Res Int (2012) 0.89
Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathy. Int J Cardiovasc Imaging (2010) 0.88
Cardiac repair with adult bone marrow-derived cells: the clinical evidence. Antioxid Redox Signal (2009) 0.88
Granulocyte colony-stimulating factor enhances bone marrow mononuclear cell homing to the liver in a mouse model of acute hepatic injury. Dig Dis Sci (2010) 0.88
Transplanted bone marrow stem cells relocate to infarct penumbra and co-express endogenous proliferative and immature neuronal markers in a mouse model of ischemic cerebral stroke. BMC Neurosci (2010) 0.87
MRI-3D ultrasound-X-ray image fusion with electromagnetic tracking for transendocardial therapeutic injections: in-vitro validation and in-vivo feasibility. Comput Med Imaging Graph (2013) 0.86
Cardiac regeneration using pluripotent stem cells--progression to large animal models. Stem Cell Res (2014) 0.86
Stem cell therapy and breast cancer treatment: review of stem cell research and potential therapeutic impact against cardiotoxicities due to breast cancer treatment. Front Oncol (2014) 0.85
Stem cells therapy for cardiovascular repair in ischemic heart disease: How to predict and secure optimal outcome? EPMA J (2011) 0.85
Recent advances in the diagnosis and treatment of acute myocardial infarction. World J Cardiol (2015) 0.85
Myocardial therapeutic angiogenesis: a review of the state of development and future obstacles. Expert Rev Cardiovasc Ther (2011) 0.83
Stem Cells for Neurovascular Repair in Stroke. J Stem Cell Res Ther (2013) 0.83
Tracking stem cells for cardiovascular applications in vivo: focus on imaging techniques. Imaging Med (2011) 0.81
Drugs, gene transfer, signaling factors: a bench to bedside approach to myocardial stem cell therapy. Heart Fail Rev (2007) 0.80
A dosing study of bone marrow mononuclear cells for transendocardial injection in a pig model of chronic ischemic heart disease. Tex Heart Inst J (2011) 0.79
Impact of intracoronary reinfusion of bone marrow-derived mononuclear progenitor cells on cardiopulmonary exercise capacity in patients with chronic postinfarction heart failure. Clin Res Cardiol (2013) 0.78
The effectiveness of rigid pericardial endoscopy for minimally invasive minor surgeries: cell transplantation, epicardial pacemaker lead implantation, and epicardial ablation. J Cardiothorac Surg (2012) 0.78
Ventricular fibrillation following autologous intramyocardial cell therapy for inherited cardiomyopathy. Cardiovasc Pathol (2008) 0.78
Cardiac tissue engineering and regeneration using cell-based therapy. Stem Cells Cloning (2015) 0.78
Clinical trials of cardiac repair with adult bone marrow- derived cells. Methods Mol Biol (2013) 0.77
Validation of QwikStar Catheter for left ventricular electromechanical mapping with NOGA XP system. Tex Heart Inst J (2008) 0.76
Conditioned umbilical cord tissue provides a natural three-dimensional storage compartment as in vitro stem cell niche for human mesenchymal stroma/stem cells. Stem Cell Res Ther (2016) 0.76
Nuclear imaging in cardiac cell therapy. Heart Fail Rev (2006) 0.76
Proinflammatory stem cell signaling in cardiac ischemia. Antioxid Redox Signal (2009) 0.76
Granulocyte colony-stimulating factor does not enhance recruitment of bone marrow-derived cells in rats with acute myocardial infarction. Exp Clin Cardiol (2012) 0.76
Stem Cell-Based Therapies in Chagasic Cardiomyopathy. Biomed Res Int (2015) 0.76
Bioengineering to enhance progenitor cell therapeutics. Tex Heart Inst J (2009) 0.76
Cellular Therapy for Heart Failure. Curr Cardiol Rev (2016) 0.75
Adult progenitor cells for cardiac repair: preclinical studies. Tex Heart Inst J (2009) 0.75
Adipose Stem Cells Display Higher Regenerative Capacities and More Adaptable Electro-Kinetic Properties Compared to Bone Marrow-Derived Mesenchymal Stromal Cells. Sci Rep (2016) 0.75
Cardiac and renal cell therapies: similarities and differences. Kidney Int Suppl (2011) (2011) 0.75
Potential and clinical utility of stem cells in cardiovascular disease. Stem Cells Cloning (2010) 0.75
Safety and feasibility of mapping and stem cell delivery in the presence of an implanted left ventricular assist device: a preclinical investigation in sheep. Tex Heart Inst J (2013) 0.75
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med (2008) 43.36
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet (2009) 10.52
Coronary intervention for persistent occlusion after myocardial infarction. N Engl J Med (2006) 8.74
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation (2003) 8.61
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med (2013) 6.01
Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation (2003) 5.34
A randomized trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med (2009) 4.46
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation (2003) 3.94
Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation (2005) 3.83
Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol (2007) 3.48
The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation (2003) 3.45
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest (2006) 3.22
Impact of collateral flow to the occluded infarct-related artery on clinical outcomes in patients with recent myocardial infarction: a report from the randomized occluded artery trial. Circulation (2010) 2.88
Leukocyte count and coronary heart disease: implications for risk assessment. J Am Coll Cardiol (2004) 2.74
The role of periadventitial fat in atherosclerosis. Arch Pathol Lab Med (2007) 2.59
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet (2009) 2.50
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol (2005) 2.42
Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Circulation (2003) 2.28
Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy. Circ Res (2012) 2.25
Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation (2003) 2.11
Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction. J Mol Cell Cardiol (2007) 2.04
C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol (2006) 1.96
Vulnerable atherosclerotic plaque: a multifocal disease. Circulation (2003) 1.84
Development of a network to test strategies in cardiovascular cell delivery: the NHLBI-sponsored Cardiovascular Cell Therapy Research Network (CCTRN). J Cardiovasc Transl Res (2010) 1.84
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet (2010) 1.83
Hippo signaling impedes adult heart regeneration. Development (2013) 1.81
Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study. Circ Cardiovasc Genet (2009) 1.80
Coming of age of C-reactive protein: using inflammation markers in cardiology. Circulation (2003) 1.74
Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med (2007) 1.72
Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A (2012) 1.72
Regional myocardial deformation in children with hypertrophic cardiomyopathy: morphological and clinical correlations. Eur Heart J (2007) 1.70
Obesity in diabetic patients undergoing coronary artery bypass graft surgery is associated with increased postoperative morbidity. Anesthesiology (2006) 1.70
Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. J Am Coll Cardiol (2005) 1.67
Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. Circulation (2003) 1.63
Gene stage-specific expression in the microenvironment of pediatric myelodysplastic syndromes. Leuk Res (2006) 1.62
Influence of pleurotomy on pulmonary function after off-pump coronary artery bypass grafting. Ann Thorac Surg (2007) 1.60
Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors. Stem Cell Res Ther (2013) 1.56
Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways. Circulation (2004) 1.55
E2F-1 regulates nuclear factor-kappaB activity and cell adhesion: potential antiinflammatory activity of the transcription factor E2F-1. Circulation (2002) 1.54
Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet (2010) 1.52
LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction. Tex Heart Inst J (2010) 1.52
Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy. Circ Res (2007) 1.51
Outcomes in patients with diabetes mellitus undergoing percutaneous coronary intervention in the current era: a report from the Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial. Circulation (2004) 1.51
Autologous cell-based therapy for ischemic heart disease: clinical evidence, proposed mechanisms of action, and current limitations. Catheter Cardiovasc Interv (2009) 1.50
[Safety of intra-arterial autologous bone marrow mononuclear cell transplantation for acute ischemic stroke]. Arq Bras Cardiol (2006) 1.50
Preoperative statin therapy decreases risk of postoperative renal insufficiency. Cardiovasc Ther (2010) 1.47
Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study. Eur J Clin Invest (2010) 1.47
Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res (2011) 1.47
ACCF/AHA consensus conference report on professionalism and ethics. Circulation (2004) 1.47
Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation (2004) 1.46
Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER). Circ Cardiovasc Qual Outcomes (2009) 1.46
Lung cancer after heart transplantation: a 17-year experience. Ann Thorac Surg (2005) 1.39
Adult stem cell therapy in perspective. Circulation (2003) 1.38
Preserved homograft function 32 years after surgery in a young patient. J Thorac Cardiovasc Surg (2010) 1.38
Assessing myocardial viability and infarct transmurality with left ventricular electromechanical mapping in patients with stable coronary artery disease: validation by delayed-enhancement magnetic resonance imaging. Circulation (2002) 1.36
A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF). Am Heart J (2011) 1.35
Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ Res (2005) 1.34
Statins are associated with a reduced incidence of perioperative mortality after coronary artery bypass graft surgery. Circulation (2004) 1.32
Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation (2009) 1.30
The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy. Circ Res (2013) 1.30
Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations. Cell Tissue Res (2004) 1.29
Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res (2009) 1.28
Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action. Circ Res (2010) 1.26
Combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells increases benefits in infarcted swine hearts. Arterioscler Thromb Vasc Biol (2009) 1.22
Acquired commissural fusion of aortic valves in patients with left ventricular assist devices. J Heart Lung Transplant (2003) 1.22
The use of high-sensitivity assays for C-reactive protein in clinical practice. Nat Clin Pract Cardiovasc Med (2008) 1.21
Randomized, double-blind pilot study of transendocardial injection of autologous aldehyde dehydrogenase-bright stem cells in patients with ischemic heart failure. Am Heart J (2012) 1.19