Published in Diabetologia on September 09, 2004
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nat Med (2007) 2.23
Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol (2010) 1.05
Associations between plasma homocysteine levels, aortic stiffness and wave reflection in patients with arterial hypertension, isolated office hypertension and normotensive controls. J Hum Hypertens (2009) 0.92
Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes. Diabetes (2014) 0.91
Spironolactone reduces brachial pulse wave velocity and PIIINP levels in hypertensive diabetic patients. Br J Clin Pharmacol (2005) 0.89
Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects. Diabetes Obes Metab (2013) 0.85
The necessity and effectiveness of mineralocorticoid receptor antagonist in the treatment of diabetic nephropathy. Hypertens Res (2015) 0.81
The role of mineralocorticoid receptor antagonists (MRAs) in very old patients with heart failure. Heart Fail Rev (2012) 0.80
Mineralocorticoid receptor antagonists and endothelial function. Curr Opin Investig Drugs (2008) 0.80
Homocysteine levels are associated with the results of 123I-metaiodobenzylguanidine myocardial scintigraphy in type 2 diabetic patients. Eur J Nucl Med Mol Imaging (2006) 0.78
Effect of eplerenone on insulin action in essential hypertension: a randomised, controlled, crossover study. J Hum Hypertens (2014) 0.77
Quantifying the effects of diuretics and β-adrenoceptor blockers on glycaemic control in diabetes mellitus - a systematic review and meta-analysis. Br J Clin Pharmacol (2015) 0.76
Aldosterone promotes cardiac endothelial cell proliferation in vivo. J Am Heart Assoc (2015) 0.76
Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury. J Pharmacol Exp Ther (2015) 0.76
Impact of spironolactone on endothelial function in patients with single ventricle heart. Congenit Heart Dis (2009) 0.76
Effect of Selective Mineralocorticoid Receptor Blockade on Flow-Mediated Dilation and Insulin Resistance in Older Adults with Metabolic Syndrome. Metab Syndr Relat Disord (2015) 0.76
The endothelial mineralocorticoid receptor: mediator of the switch from vascular health to disease. Curr Opin Nephrol Hypertens (2016) 0.75
Eplerenone: is it time to add this drug to current heart failure therapy? Ther Adv Chronic Dis (2012) 0.75
Autonomic effects of spironolactone and MR blockers in heart failure. Heart Fail Rev (2005) 0.75
Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother (1972) 61.10
The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med (1994) 27.68
Echocardiography in chronic heart failure in the community. Q J Med (1993) 7.64
Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH. Am J Gastroenterol (1987) 7.09
Value of natriuretic peptides in assessment of patients with possible new heart failure in primary care. Lancet (1997) 6.48
Is informed consent always necessary for randomized, controlled trials? . N Engl J Med (1999) 6.32
Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes. Diabetologia (2003) 4.33
QT dispersion and sudden unexpected death in chronic heart failure. Lancet (1994) 4.17
Investigation in general practice of patients with suspected heart failure. How should the essential echocardiographic service be delivered? Br Heart J (1995) 3.86
Uses of barium meal examination in dyspeptic patients under 50. Br Med J (1977) 3.82
Inhibition of beta-lactamases by beta-lactam antibiotics. Antimicrob Agents Chemother (1972) 3.72
Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee. Intensive Care Med (1994) 3.21
Pertussis is a frequent cause of prolonged cough illness in adults and adolescents. Clin Infect Dis (2001) 3.11
Has misdiagnosis of appendicitis decreased over time? A population-based analysis. JAMA (2001) 3.06
Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels. Diabet Med (2008) 2.85
Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study. Heart (2002) 2.83
Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension (2000) 2.55
Seroepidemiology of Campylobacter pyloridis. N Z Med J (1986) 2.52
Sensitivity and specificity of QTc dispersion for identification of risk of cardiac death in patients with peripheral vascular disease. BMJ (1996) 2.43
Detection of left ventricular dysfunction after acute myocardial infarction: comparison of clinical, echocardiographic, and neurohormonal methods. Br Heart J (1994) 2.32
Plasma brain natriuretic peptide as an indicator for angiotensin-converting-enzyme inhibition after myocardial infarction. Lancet (1993) 2.30
The effect of different doses of vitamin D(3) on markers of vascular health in patients with type 2 diabetes: a randomised controlled trial. Diabetologia (2010) 2.26
A pilot study of naltrexone-accelerated detoxification in opioid dependence. Med J Aust (1999) 2.13
Left ventricular hypertrophy: reduction of blood pressure already in the normal range further regresses left ventricular mass. Heart (2009) 2.12
Task-based learning: the answer to integration and problem-based learning in the clinical years. Med Educ (2000) 2.10
Cutaneous malignant melanoma in Scotland: incidence, survival, and mortality, 1979-94. The Scottish Melanoma Group. BMJ (1997) 2.08
Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Consensus Committee. J Crit Care (1994) 2.07
Further defining the role for natriuretic peptide levels in clinical practice. Eur Heart J (1999) 2.06
Rapid diagnosis of Campylobacter pyloridis infection. Lancet (1986) 2.03
Urate predicts subsequent cardiac death in stroke survivors. Eur Heart J (2002) 2.02
Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency. Am J Hum Genet (1999) 1.99
Fetal alcohol syndrome: a prospective national surveillance study. Arch Dis Child (2007) 1.98
Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma. Eur J Clin Pharmacol (1989) 1.88
A medium-density genetic linkage map of the bovine genome. Mamm Genome (1997) 1.85
Kinetics of the antibody response to tetanus-diphtheria-acellular pertussis vaccine in women of childbearing age and postpartum women. Clin Infect Dis (2011) 1.84
Ophthalmic survey of a diabetic clinic. I: Ocular findings. Br J Ophthalmol (1986) 1.80
Effect of intravenous adrenaline on electrocardiogram, blood pressure, and serum potassium. Br Heart J (1983) 1.79
Interventions for impetigo. Cochrane Database Syst Rev (2004) 1.78
Prevalence and predictors of disability in valued life activities among individuals with rheumatoid arthritis. Ann Rheum Dis (2005) 1.77
Community-acquired pneumonia: the annual cost to the National Health Service in the UK. Eur Respir J (1997) 1.75
Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J Immunol (2000) 1.74
DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans. Hypertension (1999) 1.71
Adverse cardiac effects of salt with fludrocortisone in hypertension. Hypertension (2001) 1.70
Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation (2000) 1.70
Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency. Lancet (2001) 1.64
Investigation in general practice of patients with suspected heart failure: how should the essential echocardiographic service be delivered? Br J Gen Pract (1995) 1.63
Bronchiectasis in Alaska Native children: causes and clinical courses. Pediatr Pulmonol (2000) 1.63
Aldosterone blunts the baroreflex response in man. Clin Sci (Lond) (1998) 1.60
A comparison between B-type natriuretic peptide, global registry of acute coronary events (GRACE) score and their combination in ACS risk stratification. Heart (2009) 1.59
A genome scan for QTL influencing milk production and health traits in dairy cattle. Physiol Genomics (1999) 1.57
QT dispersion in essential hypertension. QJM (1995) 1.57
Comparison of atrial natriuretic peptide B-type natriuretic peptide, and N-terminal proatrial natriuretic peptide as indicators of left ventricular systolic dysfunction. Am J Cardiol (1996) 1.56
The effects of cardioselective and non-selective beta-adrenoceptor blockade on the hypokalaemic and cardiovascular responses to adrenomedullary hormones in man. Clin Sci (Lond) (1983) 1.56
The L-arginine:nitric oxide pathway is the major source of plasma nitrite in fasted humans. Biochem Biophys Res Commun (1995) 1.56
Enalapril reduces QTc dispersion in mild congestive heart failure secondary to coronary artery disease. Am J Cardiol (1997) 1.55
Venous and arterial gas embolism associated with positive pressure ventilation. Chest (1998) 1.52
Maintenance of lower proportions of (n - 6) eicosanoid precursors in phospholipids of human plasma in response to added dietary (n - 3) fatty acids. Biochim Biophys Acta (1992) 1.50
Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils. J Dairy Sci (2009) 1.48
Temporal evolution in the management of acute ST elevation myocardial infarction: the seven-year GUSTO experience from canada and the united states. The North American GUSTO-I and GUSTO-III investigators. Can J Cardiol (2000) 1.47
A prospective randomised trial of absorbable versus non-absorbable sutures for wound closure after fasciectomy for Dupuytren's contracture. J Hand Surg Eur Vol (2009) 1.42
QT and QTc dispersion are accurate predictors of cardiac death in newly diagnosed non-insulin dependent diabetes: cohort study. BMJ (1998) 1.41
Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains. J Biol Chem (1996) 1.41
How to use natriuretic peptide levels for diagnosis and prognosis. Eur Heart J (1999) 1.41
Effectiveness of captopril in reversing renal vasoconstriction after Q-wave acute myocardial infarction. Am J Cardiol (1993) 1.40
Raised plasma concentrations of brain natriuretic peptide in pulmonary arterial hypertension. Respir Med (1995) 1.39
Heart failure: a diagnostic and therapeutic dilemma in elderly patients. Age Ageing (1998) 1.38
The mode of action of novobiocin. Prog Med Chem (1971) 1.37
Correlation between hydrolysis of the -lactam bond of the cephalosporin nucleus and expulsion of the 3-substituent. J Bacteriol (1972) 1.32
Do managed clinical networks improve quality of diabetes care? Evidence from a retrospective mixed methods evaluation. Qual Saf Health Care (2009) 1.31
Systemic beta-adrenoceptor responses to salbutamol given by metered-dose inhaler alone and with pear shaped spacer attachment: comparison of electrocardiographic, hypokalaemic and haemodynamic effects. Br J Clin Pharmacol (1989) 1.29
Ophthalmic survey of a diabetic clinic: II. Requirements for treatment of retinopathy. Br J Ophthalmol (1986) 1.27
Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure. Heart (2005) 1.26
Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. Cardiovasc Res (1997) 1.24
Mapping quantitative trait loci with DNA microsatellites in a commercial dairy cattle population. Anim Genet (1994) 1.22
Sex differences in hypokalaemic and electrocardiographic effects of inhaled terbutaline. Thorax (1992) 1.21
Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics. Am Rev Respir Dis (1989) 1.20
Regulation of cellular antibody synthesis effect of adoptively transferred antibody-producing spleen cells on cellular antibody synthesis. J Immunol (1968) 1.19
Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF). Br J Cancer (2001) 1.18
Misidentification rate in the Israeli dairy cattle population and its implications for genetic improvement. J Dairy Sci (1996) 1.18
Clinically significant Streptococcus anginosus (Streptococcus milleri) infections: a review of 186 cases. N Z Med J (1988) 1.17
Cytochalasin D does not produce net depolymerization of actin filaments in HEp-2 cells. Nature (1980) 1.16
Effects of monoclonal antibodies to the alpha and beta chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions. Eur J Immunol (1985) 1.16
The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon. EMBO J (1990) 1.15
Human calcitonin gene related peptide: a potent endogenous vasodilator in man. Clin Sci (Lond) (1986) 1.15
Prior thiazide diuretic treatment increases adrenaline-induced hypokalaemia. Lancet (1983) 1.14
Membrane binding of phospholipases C-beta 1 and C-beta 2 is independent of phosphatidylinositol 4,5-bisphosphate and the alpha and beta gamma subunits of G proteins. Biochemistry (1996) 1.14
Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol. Thorax (1995) 1.14
Sp1 binding is critical for promoter assembly and activation of the MCP-1 gene by tumor necrosis factor. J Biol Chem (2000) 1.13
More than skin deep: atherosclerosis as a systemic manifestation of psoriasis. Br J Dermatol (2009) 1.13
The role of adrenal medullary catecholamines in potassium homoeostasis. Clin Sci (Lond) (1984) 1.13
A frameshift mutation in exon 28 of the OPA1 gene explains the high prevalence of dominant optic atrophy in the Danish population: evidence for a founder effect. Hum Genet (2001) 1.12
Perindopril improves six minute walking distance in older patients with left ventricular systolic dysfunction: a randomised double blind placebo controlled trial. Heart (2002) 1.12
Elevated levels of brain natriuretic peptide in acute hypoxaemic chronic obstructive pulmonary disease. Clin Sci (Lond) (1992) 1.12
Quantitative effects of dietary polyunsaturated fats on the composition of fatty acids in rat tissues. Lipids (1990) 1.11
Plasma concentrations of brain natriuretic peptide: will this new test reduce the need for cardiac investigations? Br Heart J (1993) 1.11
Identification of two binding sites for wheat-germ agglutinin on polylactosamine-type oligosaccharides. Biochem J (1985) 1.11