Published in EMBO J on July 01, 1990
Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site. Proc Natl Acad Sci U S A (1990) 1.53
The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells. J Cancer Res Clin Oncol (2006) 1.16
Critical role for the Val/Gly86 HLA-DR beta dimorphism in autoantigen presentation to human T cells. Proc Natl Acad Sci U S A (1991) 1.00
hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome. Hum Mol Genet (2008) 1.00
Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome. Hum Mol Genet (2009) 0.96
Human nicotinic acetylcholine receptor alpha-subunit isoforms: origins and expression. Nucleic Acids Res (1993) 0.92
Functional and non-functional isoforms of the human muscle acetylcholine receptor. J Physiol (1995) 0.92
Use of a mammalian interspersed repetitive (MIR) element in the coding and processing sequences of mammalian genes. Nucleic Acids Res (1995) 0.92
Differential expression of human nicotinic acetylcholine receptor alpha subunit variants in muscle and non-muscle tissues. Nucleic Acids Res (1993) 0.90
Antigen-specific modulation of experimental myasthenia gravis: nasal tolerization with recombinant fragments of the human acetylcholine receptor alpha-subunit. Proc Natl Acad Sci U S A (1999) 0.89
Regulation of acetylcholine receptor alpha subunit variants in human myasthenia gravis. Quantification of steady-state levels of messenger RNA in muscle biopsy using the polymerase chain reaction. J Clin Invest (1994) 0.87
Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss. J Clin Invest (1998) 0.86
HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA. Sci Rep (2013) 0.82
Involvement of human muscle acetylcholine receptor alpha-subunit gene (CHRNA) in susceptibility to myasthenia gravis. Proc Natl Acad Sci U S A (1994) 0.82
Principles of agonist recognition in Cys-loop receptors. Front Physiol (2014) 0.82
Acetylcholine receptor-alpha subunit expression in myasthenia gravis: a role for the autoantigen in pathogenesis? Muscle Nerve (2009) 0.80
Acetylcholine receptor alpha-subunit isoforms are differentially expressed in thymuses from myasthenic patients. Am J Pathol (1997) 0.78
Vaccines against myasthenia gravis. Expert Opin Biol Ther (2005) 0.76
Decoding pathogenesis of slow-channel congenital myasthenic syndromes using recombinant expression and mice models. P R Health Sci J (2010) 0.76
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1990) 0.75
High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor. PLoS One (2016) 0.75
Presentation of endogenous acetylcholine receptor antigen to a specific CD4+ T-cell line by a transfected B-cell line. Immunology (1995) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene (1982) 102.30
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82
A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. Gene (1982) 59.01
Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. Proc Natl Acad Sci U S A (1978) 14.82
Acetylcholine receptor: complex of homologous subunits. Science (1980) 3.45
Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor. Nature (1983) 2.78
Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies. Proc Natl Acad Sci U S A (1982) 2.22
Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays. J Neurol Neurosurg Psychiatry (1985) 2.11
Isolation and characterization of the beta and epsilon subunit genes of mouse muscle acetylcholine receptor. J Biol Chem (1989) 1.94
Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system. Cell (1987) 1.90
Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor. J Neurosci (1985) 1.80
The molecular cloning and characterisation of cDNA coding for the alpha subunit of the acetylcholine receptor. Nucleic Acids Res (1982) 1.80
Activity regulates the levels of acetylcholine receptor alpha-subunit mRNA in cultured chicken myotubes. Proc Natl Acad Sci U S A (1985) 1.73
Mapping the main immunogenic region and toxin-binding site of the nicotinic acetylcholine receptor. Science (1987) 1.57
Immunology of acetylcholine receptors in relation to myasthenia gravis. Physiol Rev (1980) 1.54
Genes expressed in the brain define three distinct neuronal nicotinic acetylcholine receptors. EMBO J (1988) 1.39
Muscle denervation increases the levels of two mRNAs coding for the acetylcholine receptor alpha-subunit. J Neurosci (1985) 1.35
Transcriptional regulation of nicotinic acetylcholine receptor genes during muscle development. J Biol Chem (1986) 1.34
A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671. J Neurosci (1989) 1.25
Monoclonal antibodies as probes of acetylcholine receptor structure. 1. Peptide mapping. Biochemistry (1981) 1.23
Molecular structure of the nicotinic acetylcholine receptor. Cold Spring Harb Symp Quant Biol (1983) 1.10
The human medulloblastoma cell line TE671 expresses a muscle-like acetylcholine receptor. Cloning of the alpha-subunit cDNA. FEBS Lett (1988) 1.05
Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence. Eur J Biochem (1985) 1.05
Subunit structure and peptide mapping of junctional and extrajunctional acetylcholine receptors from rat muscle. Biochemistry (1979) 1.03
Monoclonal antibodies to the main immunogenic region of the nicotinic acetylcholine receptor bind to residues 61-76 of the alpha subunit. J Biol Chem (1988) 0.99
Mammalian muscle acetylcholine receptor purification and characterization. Biochemistry (1982) 0.98
Differential expression of nicotinic acetylcholine receptor genes in innervated and denervated chicken muscle. EMBO J (1987) 0.97
Subunit composition of bovine muscle acetylcholine receptor. Biochemistry (1982) 0.92
Epitopes on human acetylcholine receptor defined by monoclonal antibodies and myasthenia gravis sera. Autoimmunity (1988) 0.90
Similarity of acetylcholine receptors of denervated, innervated and embryonic chicken muscles. 2. Subunit compositions. Eur J Biochem (1982) 0.90
Purification and biochemical characterization of nicotinic acetylcholine receptors of human muscle. J Biol Chem (1982) 0.89
Coordinate regulation of RNAs encoding two isoforms of the rat muscle nicotinic acetylcholine receptor beta-subunit. Nucleic Acids Res (1989) 0.85
Structural heterogeneity of the alpha subunits of the nicotinic acetylcholine receptor in relation to agonist affinity alkylation and antagonist binding. Biochemistry (1986) 0.84
Linkage disequilibrium study of RFLPs detected at the human muscle nicotinic acetylcholine receptor subunit genes. Am J Hum Genet (1989) 0.81
The isolation and characterisation of the nicotinic acetylcholine receptor from human skeletal muscle. Eur J Biochem (1981) 0.77
Immunological and pharmacological heterogeneity of alpha-bungarotoxin binding sites extracted from TE671 cells. J Neuroimmunol (1988) 0.77
Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother (1972) 61.10
The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med (1994) 27.68
Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry (2004) 10.58
Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH. Am J Gastroenterol (1987) 7.09
Is informed consent always necessary for randomized, controlled trials? . N Engl J Med (1999) 6.32
Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes. Diabetologia (2003) 4.33
Uses of barium meal examination in dyspeptic patients under 50. Br Med J (1977) 3.82
Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays. Neurology (2012) 3.79
Inhibition of beta-lactamases by beta-lactam antibiotics. Antimicrob Agents Chemother (1972) 3.72
Viral RNA annealing activities of human immunodeficiency virus type 1 nucleocapsid protein require only peptide domains outside the zinc fingers. Proc Natl Acad Sci U S A (1992) 3.71
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med (2001) 3.26
Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee. Intensive Care Med (1994) 3.21
Pertussis is a frequent cause of prolonged cough illness in adults and adolescents. Clin Infect Dis (2001) 3.11
Potassium channel antibodies in two patients with reversible limbic encephalitis. Ann Neurol (2001) 3.06
Has misdiagnosis of appendicitis decreased over time? A population-based analysis. JAMA (2001) 3.06
Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain (2008) 2.96
Acquired neuromyotonia: evidence for autoantibodies directed against K+ channels of peripheral nerves. Ann Neurol (1995) 2.79
The Lambert-Eaton myasthenic syndrome. A review of 50 cases. Brain (1988) 2.73
Sequence and structure of the serendipity locus of Drosophila melanogaster. A densely transcribed region including a blastoderm-specific gene. J Mol Biol (1985) 2.58
Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy. Neurology (2007) 2.55
Serum antibodies in epilepsy and seizure-associated disorders. Neurology (2005) 2.53
A Drosophila Minute gene encodes a ribosomal protein. Nature (1985) 2.53
Seroepidemiology of Campylobacter pyloridis. N Z Med J (1986) 2.52
Autoimmune aetiology for myasthenic (Eaton-Lambert) syndrome. Lancet (1981) 2.36
Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain (1980) 2.36
ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature (1999) 2.32
Autoimmune aetiology for acquired neuromyotonia (Isaacs' syndrome) Lancet (1991) 2.28
Autoantibodies detected to expressed K+ channels are implicated in neuromyotonia. Ann Neurol (1997) 2.17
Anti-Ma and anti-Ta associated paraneoplastic neurological syndromes: 22 newly diagnosed patients and review of previous cases. J Neurol Neurosurg Psychiatry (2008) 2.16
Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels. Brain (2001) 2.14
Progressive encephalomyelitis, rigidity, and myoclonus: a novel glycine receptor antibody. Neurology (2008) 2.13
A pilot study of naltrexone-accelerated detoxification in opioid dependence. Med J Aust (1999) 2.13
Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays. J Neurol Neurosurg Psychiatry (1985) 2.11
Cutaneous malignant melanoma in Scotland: incidence, survival, and mortality, 1979-94. The Scottish Melanoma Group. BMJ (1997) 2.08
Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics. EMBO J (1994) 2.08
Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Consensus Committee. J Crit Care (1994) 2.07
Immunotherapy-responsive seizure-like episodes with potassium channel antibodies. Neurology (2008) 2.06
P/Q type calcium-channel antibodies in paraneoplastic cerebellar degeneration with lung cancer. Neurology (2002) 2.05
Rapid diagnosis of Campylobacter pyloridis infection. Lancet (1986) 2.03
Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency. Am J Hum Genet (1999) 1.99
Fetal alcohol syndrome: a prospective national surveillance study. Arch Dis Child (2007) 1.98
Cricoid pressure: can protective force be sustained? Br J Anaesth (1998) 1.97
Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigen. Lancet (1995) 1.94
Progressive encephalomyelitis with rigidity and myoclonus: glycine and NMDA receptor antibodies. Neurology (2011) 1.93
Cerebellar ataxia with anti-glutamic acid decarboxylase antibodies: study of 14 patients. Arch Neurol (2001) 1.90
Clinical aspects of MuSK antibody positive seronegative MG. Neurology (2003) 1.89
Kinetics of the antibody response to tetanus-diphtheria-acellular pertussis vaccine in women of childbearing age and postpartum women. Clin Infect Dis (2011) 1.84
Successful treatment of anti-N-methyl-D-aspartate receptor encephalitis presenting with catatonia. Arch Dis Child (2009) 1.84
Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island. Science (1991) 1.82
Ophthalmic survey of a diabetic clinic. I: Ocular findings. Br J Ophthalmol (1986) 1.80
Interventions for impetigo. Cochrane Database Syst Rev (2004) 1.78
Acetylcholine receptor antibody characteristics in myasthenia gravis. I. Patients with generalized myasthenia or disease restricted to ocular muscles. Clin Exp Immunol (1982) 1.78
Prevalence and predictors of disability in valued life activities among individuals with rheumatoid arthritis. Ann Rheum Dis (2005) 1.77
NMO-IgG in the diagnosis of neuromyelitis optica. Neurology (2007) 1.77
Paraneoplastic myasthenic syndrome IgG inhibits 45Ca2+ flux in a human small cell carcinoma line. Nature (1985) 1.76
Community-acquired pneumonia: the annual cost to the National Health Service in the UK. Eur Respir J (1997) 1.75
Prevention of autoimmune attack by targeting specific T-cell receptors in a severe combined immunodeficiency mouse model of myasthenia gravis. Ann Neurol (1999) 1.75
Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J Immunol (2000) 1.74
A somatically mutated human antiganglioside IgM antibody that induces experimental neuropathy in mice is encoded by the variable region heavy chain gene, V1-18. J Clin Invest (1996) 1.74
TFIIIA and homologous genes. The 'finger' proteins. Nucleic Acids Res (1986) 1.74
Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome. Brain (1997) 1.73
Hu and voltage-gated calcium channel (VGCC) antibodies related to the prognosis of small-cell lung cancer. J Clin Oncol (2004) 1.71
Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones. Proc Natl Acad Sci U S A (1983) 1.71
Function of circulating antibody to acetylcholine receptor in myasthenia gravis: investigation by plasma exchange. Neurology (1978) 1.71
Serum factor in Miller-Fisher variant of Guillain-Barré syndrome and neurotransmitter release. Lancet (1994) 1.69
Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency. Lancet (2001) 1.64
Bronchiectasis in Alaska Native children: causes and clinical courses. Pediatr Pulmonol (2000) 1.63
Creutzfeldt-Jakob disease after administration of human growth hormone. Lancet (1985) 1.61
Brain abnormalities in Sjogren syndrome with recurrent CNS manifestations: association with neuromyelitis optica. Mult Scler (2009) 1.58
Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines. J Infect (2011) 1.57
Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome. J Neurol Sci (1997) 1.56
Immunology of acetylcholine receptors in relation to myasthenia gravis. Physiol Rev (1980) 1.54
Venous and arterial gas embolism associated with positive pressure ventilation. Chest (1998) 1.52
Acetylcholine receptor expression in human extraocular muscles and their susceptibility to myasthenia gravis. Ann Neurol (1997) 1.50
Maintenance of lower proportions of (n - 6) eicosanoid precursors in phospholipids of human plasma in response to added dietary (n - 3) fatty acids. Biochim Biophys Acta (1992) 1.50
An improved diagnostic assay for Lambert-Eaton myasthenic syndrome. J Neurol Neurosurg Psychiatry (1995) 1.49
Neurological paraneoplastic syndromes in patients with small cell lung cancer. A prospective survey of 150 patients. J Neurol Neurosurg Psychiatry (1991) 1.49
Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils. J Dairy Sci (2009) 1.48
Pharmacokinetics and bronchial diffusion of single daily dose amikacin in cystic fibrosis patients. J Antimicrob Chemother (1997) 1.48
Temporal evolution in the management of acute ST elevation myocardial infarction: the seven-year GUSTO experience from canada and the united states. The North American GUSTO-I and GUSTO-III investigators. Can J Cardiol (2000) 1.47
Strength-duration properties of peripheral nerve in acquired neuromyotonia. Muscle Nerve (1999) 1.46
Controlled trial of plasma exchange in acute inflammatory polyradiculoneuropathy. Lancet (1984) 1.43
A prospective randomised trial of absorbable versus non-absorbable sutures for wound closure after fasciectomy for Dupuytren's contracture. J Hand Surg Eur Vol (2009) 1.42
Trans-activation of the 5' to 3' viral DNA strand transfer by nucleocapsid protein during reverse transcription of HIV1 RNA. C R Acad Sci III (1993) 1.42
Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains. J Biol Chem (1996) 1.41
Paraneoplastic cerebellar degeneration. III. Cerebellar degeneration, cancer, and the Lambert-Eaton myasthenic syndrome. Neurology (1992) 1.41