Published in Biochemistry on September 07, 2004
Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase. Chem Res Toxicol (2009) 1.03
Enzymatic neutralization of the chemical warfare agent VX: evolution of phosphotriesterase for phosphorothiolate hydrolysis. J Am Chem Soc (2013) 0.81
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. Biochem J (2009) 0.78
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. J Med Chem (2002) 1.97
Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization. Infect Immun (2002) 1.64
Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor. J Biol Chem (2002) 1.44
Evaluation of homology modeling of G-protein-coupled receptors in light of the A(2A) adenosine receptor crystallographic structure. J Med Chem (2009) 1.38
Differential proteomic analysis of the Bacillus anthracis secretome: distinct plasmid and chromosome CO2-dependent cross talk mechanisms modulate extracellular proteolytic activities. J Bacteriol (2006) 1.28
Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome. Infect Immun (2007) 1.28
Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infect Immun (2004) 1.26
Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection. PLoS Pathog (2008) 1.25
Progress and novel strategies in vaccine development and treatment of anthrax. Immunol Rev (2011) 1.19
Interaction of Yersinia pestis with macrophages: limitations in YopJ-dependent apoptosis. Infect Immun (2006) 1.17
Contribution of immunological memory to protective immunity conferred by a Bacillus anthracis protective antigen-based vaccine. Infect Immun (2004) 1.16
The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis. PLoS One (2010) 1.16
Construction of a rhamnose mutation in Bacillus anthracis affects adherence to macrophages but not virulence in guinea pigs. Microb Pathog (2005) 1.15
Search for Bacillus anthracis potential vaccine candidates by a functional genomic-serologic screen. Infect Immun (2006) 1.12
Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses. BMC Med Genomics (2008) 1.10
Xenobiotic phenols in early pregnancy amniotic fluid. Reprod Toxicol (2005) 1.10
The solute-binding component of a putative Mn(II) ABC transporter (MntA) is a novel Bacillus anthracis virulence determinant. Mol Microbiol (2005) 1.08
Yersinia pestis endowed with increased cytotoxicity is avirulent in a bubonic plague model and induces rapid protection against pneumonic plague. PLoS One (2009) 1.07
Effective protective immunity to Yersinia pestis infection conferred by DNA vaccine coding for derivatives of the F1 capsular antigen. Infect Immun (2003) 1.06
Characterization of Bacillus anthracis iron-regulated surface determinant (Isd) proteins containing NEAT domains. Mol Microbiol (2008) 1.02
The NlpD lipoprotein is a novel Yersinia pestis virulence factor essential for the development of plague. PLoS One (2009) 1.01
Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds. Mol Pharmacol (2006) 1.01
Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox. J Infect Dis (2009) 0.97
Differential contribution of Bacillus anthracis toxins to pathogenicity in two animal models. Infect Immun (2012) 0.96
Neutralization of Yersinia pestis-mediated macrophage cytotoxicity by anti-LcrV antibodies and its correlation with protective immunity in a mouse model of bubonic plague. Vaccine (2008) 0.95
HtrA is a major virulence determinant of Bacillus anthracis. Mol Microbiol (2011) 0.95
Identification of chromosomally encoded membranal polypeptides of Bacillus anthracis by a proteomic analysis: prevalence of proteins containing S-layer homology domains. Proteomics (2004) 0.94
Effective post-exposure protection against lethal orthopoxviruses infection by vaccinia immune globulin involves induction of adaptive immune response. Vaccine (2009) 0.92
The NheA component of the non-hemolytic enterotoxin of Bacillus cereus is produced by Bacillus anthracis but is not required for virulence. Microb Pathog (2004) 0.91
Clinical and immune responses after revaccination of israeli adults with the Lister strain of vaccinia virus. J Infect Dis (2004) 0.91
Discordance in the effects of Yersinia pestis on the dendritic cell functions manifested by induction of maturation and paralysis of migration. Infect Immun (2006) 0.91
Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: toxicological implications. Toxicol Appl Pharmacol (2002) 0.89
Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine. J Med Chem (2006) 0.88
Proteomic studies of Bacillus anthracis. Future Microbiol (2009) 0.87
Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides. Toxicol Lett (2002) 0.87
Effects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen. J Biol Chem (2005) 0.87
Homology model-assisted elucidation of binding sites in GPCRs. Methods Mol Biol (2012) 0.86
Identification and characterization of novel and potent transcription promoters of Francisella tularensis. Appl Environ Microbiol (2010) 0.85
T cells play an essential role in anti-F1 mediated rapid protection against bubonic plague. Vaccine (2011) 0.85
Disparity between Yersinia pestis and Yersinia enterocolitica O:8 in YopJ/YopP-dependent functions. Adv Exp Med Biol (2007) 0.84
Efficacy and safety of intravenous immunoglobulin in patients with metastatic melanoma. Ann N Y Acad Sci (2007) 0.83
Evaluation of protective immunity induced by Yersinia enterocolitica type-III secretion system mutants. Adv Exp Med Biol (2003) 0.83
Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants. J Biol Chem (2007) 0.83
Whole-genome immunoinformatic analysis of F. tularensis: predicted CTL epitopes clustered in hotspots are prone to elicit a T-cell response. PLoS One (2011) 0.83
Consequences of delayed ciprofloxacin and doxycycline treatment regimens against Francisella tularensis airway infection. Antimicrob Agents Chemother (2012) 0.82
Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase. Mol Pharmacol (2008) 0.82
The aromatic "trapping" of the catalytic histidine is essential for efficient catalysis in acetylcholinesterase. Biochemistry (2002) 0.82
Functional requirements for the optimal catalytic configuration of the AChE active center. Chem Biol Interact (2005) 0.81
Selective site controlled nucleophilic attacks in 5-membered ring phosphate esters: unusual C-O vs. common P-O bond cleavage. Chem Commun (Camb) (2005) 0.81
A novel mechanism for antibody-based anthrax toxin neutralization: inhibition of prepore-to-pore conversion. J Biol Chem (2012) 0.81
Early sensing of Yersinia pestis airway infection by bone marrow cells. Front Cell Infect Microbiol (2012) 0.80
Novel and unique diagnostic biomarkers for Bacillus anthracis infection. Appl Environ Microbiol (2009) 0.80
Host-regulated disposition of mammalian AChEs. Chem Biol Interact (2005) 0.79
In vitro screen of bioinformatically selected Bacillus anthracis vaccine candidates by coupled transcription, translation, and immunoprecipitation analysis. Methods Mol Biol (2007) 0.79
Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta). Biochem J (2004) 0.79
Vaccination with plasmid DNA expressing the Yersinia pestis capsular protein F1 protects mice against plague. Adv Exp Med Biol (2003) 0.79
Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imaging. Int J Pharm (2010) 0.79
Polyethylene-glycol conjugated recombinant human acetylcholinesterase serves as an efficacious bioscavenger against soman intoxication. Toxicology (2006) 0.78
Clusters versus affinity-based approaches in F. tularensis whole genome search of CTL epitopes. PLoS One (2012) 0.78
The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers. Chem Biol Interact (2005) 0.78
Identification of genes involved in Yersinia pestis virulence by signature-tagged mutagenesis. Adv Exp Med Biol (2003) 0.78
Overloading and removal of N-glycosylation targets on human acetylcholinesterase: effects on glycan composition and circulatory residence time. Biochem J (2002) 0.78
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. Biochem J (2009) 0.78