Published in J Cell Biochem on October 01, 2004
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J Clin Invest (2009) 2.18
Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling. Arthritis Res Ther (2007) 1.47
A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem (2005) 1.30
Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation. J Cell Biochem (2008) 1.19
Concise review: adipose-derived stromal cells for skeletal regenerative medicine. Stem Cells (2011) 1.16
Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation. PLoS Genet (2010) 1.09
Animal models of typical heterotopic ossification. J Biomed Biotechnol (2010) 1.00
Gene identification and analysis of transcripts differentially regulated in fracture healing by EST sequencing in the domestic sheep. BMC Genomics (2006) 0.96
p204 protein overcomes the inhibition of core binding factor alpha-1-mediated osteogenic differentiation by Id helix-loop-helix proteins. Mol Biol Cell (2008) 0.95
Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice. PLoS One (2013) 0.87
Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell niche. Blood (2009) 0.85
Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways. Elife (2015) 0.83
E Proteins and ID Proteins: Helix-Loop-Helix Partners in Development and Disease. Dev Cell (2015) 0.81
Nectandrin A Enhances the BMP-Induced Osteoblastic Differentiation and Mineralization by Activation of p38 MAPK-Smad Signaling Pathway. Korean J Physiol Pharmacol (2013) 0.79
Transcriptional profiling of mesenchymal stromal cells from young and old rats in response to Dexamethasone. BMC Genomics (2006) 0.76
Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells. Invest Ophthalmol Vis Sci (2017) 0.75
Up-regulation of inhibitors of DNA binding/differentiation gene during alendronate-induced osteoblast differentiation. Arch Gynecol Obstet (2011) 0.75
E proteins regulate osteoclast maturation and survival. J Bone Miner Res (2012) 0.75
Contribution of Inhibitor of DNA Binding/Differentiation-3 and Endocrine Disrupting Chemicals to Pathophysiological Aspects of Chronic Disease. Biomed Res Int (2017) 0.75
Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature (2005) 6.43
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature (2013) 4.19
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27
NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem (2007) 2.22
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts. J Biol Chem (2007) 1.72
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol Biol Cell (2007) 1.57
Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci U S A (2002) 1.55
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption. J Cell Biochem (2010) 1.54
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism. J Biol Chem (2006) 1.52
Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proc Natl Acad Sci U S A (2012) 1.50
Nanogel-based scaffold delivery of prostaglandin E(2) receptor-specific agonist in combination with a low dose of growth factor heals critical-size bone defects in mice. Arthritis Rheum (2011) 1.50
Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice. J Bone Miner Res (2006) 1.39
Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis. J Orthop Res (2011) 1.35
Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. J Biol Chem (2005) 1.27
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells (2002) 1.20
Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin Orthop Relat Res (2013) 1.19
Transient receptor potential vanilloid 4 deficiency suppresses unloading-induced bone loss. J Cell Physiol (2008) 1.15
Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol (2004) 1.10
Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits. Arthritis Res Ther (2010) 1.10
Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res (2002) 1.09
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation. J Exp Med (2005) 1.08
BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with Acvr2b. Mol Endocrinol (2011) 1.08
Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein. J Immunol (2011) 1.07
Arthroscopic, histological and MRI analyses of cartilage repair after a minimally invasive method of transplantation of allogeneic synovial mesenchymal stromal cells into cartilage defects in pigs. Cytotherapy (2012) 1.05
Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. J Bone Miner Res (2002) 1.04
Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration. Arthritis Res Ther (2012) 1.04
Histological evidence of the altered distribution of osteocytes and bone matrix synthesis in klotho-deficient mice. Arch Histol Cytol (2005) 1.03
Angiotensin II type 2 receptor blockade increases bone mass. J Biol Chem (2008) 1.03
Bone morphogenetic protein-2 enhances osterix gene expression in chondrocytes. J Cell Biochem (2003) 1.03
Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia. J Biol Chem (2007) 1.03
Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci (2007) 1.00
Sympathetic control of bone mass regulated by osteopontin. Proc Natl Acad Sci U S A (2011) 0.99
Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblasts. J Biol Chem (2002) 0.99
Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo. J Bone Miner Res (2003) 0.98
Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells. Arthritis Rheum (2009) 0.98
Tob deficiency superenhances osteoblastic activity after ovariectomy to block estrogen deficiency-induced osteoporosis. Proc Natl Acad Sci U S A (2004) 0.97
Runx2 is a target of mechanical unloading to alter osteoblastic activity and bone formation in vivo. Endocrinology (2006) 0.97
Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation. Endocrinology (2003) 0.96
Intraarticular injection of synovial stem cells promotes meniscal regeneration in a rabbit massive meniscal defect model. J Orthop Res (2013) 0.96
Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis. Endocrinology (2004) 0.96
Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. J Endocrinol (2007) 0.95
Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. Exp Cell Res (2006) 0.95
Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor. J Cell Physiol (2009) 0.93
Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration. J Cell Biochem (2007) 0.92
Aged mice require full transcription factor, Runx2/Cbfa1, gene dosage for cancellous bone regeneration after bone marrow ablation. J Bone Miner Res (2004) 0.92
Cnot7-null mice exhibit high bone mass phenotype and modulation of BMP actions. J Bone Miner Res (2007) 0.91
Isolation and characterization of multipotential mesenchymal cells from the mouse synovium. PLoS One (2012) 0.91
Transplantation of aggregates of synovial mesenchymal stem cells regenerates meniscus more effectively in a rat massive meniscal defect. Biochem Biophys Res Commun (2013) 0.90
Intra-articular injections of bone morphogenetic protein-7 retard progression of existing cartilage degeneration. J Orthop Res (2010) 0.90
Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations. Biochim Biophys Acta (2002) 0.90
Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro. Exp Cell Res (2008) 0.90
Noggin inhibits chondrogenic but not osteogenic differentiation in mesodermal stem cell line C1 and skeletal cells. Endocrinology (2004) 0.89
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages. Arthritis Rheum (2010) 0.89
JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion. J Cell Biochem (2008) 0.89
Differences in gene expression between the otic capsule and other bones. Hear Res (2010) 0.88
ANA deficiency enhances bone morphogenetic protein-induced ectopic bone formation via transcriptional events. J Biol Chem (2009) 0.88
Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling. Sci Rep (2013) 0.87
Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures. J Bone Miner Res (2004) 0.87
Meniscus regeneration by syngeneic, minor mismatched, and major mismatched transplantation of synovial mesenchymal stem cells in a rat model. J Orthop Res (2014) 0.87
Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts. Endocrinology (2006) 0.86
Constitutively active parathyroid hormone receptor signaling in cells in osteoblastic lineage suppresses mechanical unloading-induced bone resorption. J Biol Chem (2007) 0.86
Morphological differences during in vitro chondrogenesis of bone marrow-, synovium-MSCs, and chondrocytes. Lab Invest (2009) 0.86
Mouse synovial mesenchymal stem cells increase in yield with knee inflammation. J Orthop Res (2014) 0.86
Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts. J Biol Chem (2008) 0.86
Histological and immunohistochemical changes in the submandibular gland in klotho-deficient mice. Arch Histol Cytol (2006) 0.86
PlexinD1 deficiency induces defects in axial skeletal morphogenesis. J Cell Biochem (2007) 0.85
Impaired spermatogenesis and male fertility defects in CIZ/Nmp4-disrupted mice. Genes Cells (2004) 0.85
Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation. FEBS Lett (2008) 0.85
BMPR-II is dispensable for formation of the limb skeleton. Genesis (2011) 0.84