Published in Blood on September 16, 2004
Stem cell heterogeneity: implications for aging and regenerative medicine. Blood (2012) 1.38
Gene network dynamics controlling keratinocyte migration. Mol Syst Biol (2008) 1.26
Stem cell proliferation and quiescence--two sides of the same coin. PLoS Comput Biol (2009) 1.16
Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach. Blood (2008) 1.03
Stem cell transplant into preimplantation embryo yields myocardial infarction-resistant adult phenotype. Stem Cells (2009) 1.01
Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. Genome Res (2015) 1.01
Stem cell fate analysis revisited: interpretation of individual clone dynamics in the light of a new paradigm of stem cell organization. J Biomed Biotechnol (2007) 0.93
Single-cell and coupled GRN models of cell patterning in the Arabidopsis thaliana root stem cell niche. BMC Syst Biol (2010) 0.91
Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations. Br J Cancer (2012) 0.85
Heterogeneity of non-cycling and cycling synchronized murine hematopoietic stem/progenitor cells. J Cell Physiol (2010) 0.82
Cellular population dynamics control the robustness of the stem cell niche. Biol Open (2015) 0.78
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion. Mol Cancer (2017) 0.76
Modeling the clonal heterogeneity of stem cells. Theor Biol Med Model (2010) 0.75
Transplantation Dose Alters the Differentiation Program of Hematopoietic Stem Cells. Cell Rep (2016) 0.75
Model Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and Leukemia. PLoS One (2016) 0.75
Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med (2008) 19.93
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol (2006) 8.53
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. N Engl J Med (2006) 7.42
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60). Lancet Oncol (2008) 5.50
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease. N Engl J Med (2003) 3.99
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol (2009) 3.65
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
Standard International prognostic index remains a valid predictor of outcome for patients with aggressive CD20+ B-cell lymphoma in the rituximab era. J Clin Oncol (2010) 3.17
Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications. Nat Med (2006) 3.13
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma. Blood (2013) 3.03
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood (2005) 2.99
Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med (2007) 2.97
CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group. Lancet Oncol (2011) 2.87
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol (2010) 2.71
Rescue of salivary gland function after stem cell transplantation in irradiated glands. PLoS One (2008) 2.70
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
Risks of less common cancers in proven mutation carriers with lynch syndrome. J Clin Oncol (2012) 2.59
Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers. J Clin Oncol (2009) 2.47
Practice and perception--a nationwide survey of therapy habits in sepsis. Crit Care Med (2008) 2.43
Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence Study. Nephrol Dial Transplant (2007) 2.25
The ageing haematopoietic stem cell compartment. Nat Rev Immunol (2013) 2.15
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nat Genet (2012) 2.07
Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation. Neurology (2013) 1.98
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood (2008) 1.97
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. J Exp Med (2011) 1.95
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity. Circulation (2005) 1.87
Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1). Lancet Oncol (2012) 1.86
A Limited role for p21Cip1/Waf1 in maintaining normal hematopoietic stem cell functioning. Stem Cells (2006) 1.84
Cellular barcoding tool for clonal analysis in the hematopoietic system. Blood (2010) 1.81
Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium. J Clin Oncol (2006) 1.70
Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure. Eur J Heart Fail (2011) 1.70
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly. Int J Cancer (2012) 1.67
Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro. Biophys J (2004) 1.61
MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas. Br J Haematol (2008) 1.60
A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt. PLoS Comput Biol (2011) 1.55
Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer. Clin Gastroenterol Hepatol (2009) 1.54
In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1. Dev Cell (2003) 1.53
Noise-driven stem cell and progenitor population dynamics. PLoS One (2008) 1.52
Asymmetry in skeletal distribution of mouse hematopoietic stem cell clones and their equilibration by mobilizing cytokines. J Exp Med (2014) 1.52
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood (2008) 1.47
Engraftment of syngeneic bone marrow is not more efficient after intrafemoral transplantation than after traditional intravenous administration. Exp Hematol (2010) 1.44
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults. Blood (2011) 1.39
Growth factor treatment prior to low-dose total body irradiation increases donor cell engraftment after bone marrow transplantation in mice. Blood (2002) 1.38
Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses. J Immunol (2008) 1.36
Counting stem cells: methodological constraints. Nat Methods (2012) 1.35
Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging. Stem Cells (2005) 1.35
A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity. Exp Hematol (2002) 1.30
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma. Blood (2012) 1.27
Molecular markers in low-grade gliomas: predictive or prognostic? Clin Cancer Res (2011) 1.27
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals. Diabetes Care (2006) 1.27
Two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine plus extended-field radiotherapy is superior to radiotherapy alone in early favorable Hodgkin's lymphoma: final results of the GHSG HD7 trial. J Clin Oncol (2007) 1.26
Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool. Stem Cells (2008) 1.26
Hematopoietic stem cell expansion: challenges and opportunities. Ann N Y Acad Sci (2012) 1.25
A statistical multiprobe model for analyzing cis and trans genes in genetical genomics experiments with short-oligonucleotide arrays. Genetics (2005) 1.25
Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. Blood (2009) 1.24
Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood (2013) 1.23
Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ Cardiovasc Genet (2010) 1.23
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer. Int J Cancer (2005) 1.20
Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations. Clin Cancer Res (2013) 1.17
Stem cell proliferation and quiescence--two sides of the same coin. PLoS Comput Biol (2009) 1.16
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol (2013) 1.16
The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse. Biochem Biophys Res Commun (2005) 1.16
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups. Acta Neuropathol (2015) 1.16
Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications. Stem Cells (2007) 1.15
A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood (2002) 1.13
Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer. Int J Cancer (2006) 1.11
Cellular memory and hematopoietic stem cell aging. Stem Cells (2006) 1.10
Hematopoietic stem cell aging and self-renewal. Cell Tissue Res (2007) 1.10
ChlaDub1 of Chlamydia trachomatis suppresses NF-kappaB activation and inhibits IkappaBalpha ubiquitination and degradation. Cell Microbiol (2008) 1.09
Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia. Blood (2012) 1.08
Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1. Blood (2007) 1.08
Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells. Blood (2011) 1.07
Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche? Hum Mol Genet (2006) 1.07
Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status. Genes Chromosomes Cancer (2009) 1.06
BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells. Blood (2010) 1.06
Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation. Eur J Nucl Med Mol Imaging (2010) 1.05
Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma. Haematologica (2013) 1.05