Published in Blood on January 21, 2010
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol (2011) 3.81
Clonal dynamics of native haematopoiesis. Nature (2014) 3.15
Unravelling cancer stem cell potential. Nat Rev Cancer (2013) 3.06
Diverse and heritable lineage imprinting of early haematopoietic progenitors. Nature (2013) 2.19
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature (2015) 2.06
Asymmetry in skeletal distribution of mouse hematopoietic stem cell clones and their equilibration by mobilizing cytokines. J Exp Med (2014) 1.52
Quantitative evolutionary dynamics using high-resolution lineage tracking. Nature (2015) 1.41
Counting stem cells: methodological constraints. Nat Methods (2012) 1.35
Retroviral integrations in gene therapy trials. Mol Ther (2012) 1.34
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol (2013) 1.16
High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias. J Exp Med (2014) 1.16
Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell (2014) 1.15
Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. Blood (2013) 1.13
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. Cell Stem Cell (2014) 1.02
Multiplexing clonality: combining RGB marking and genetic barcoding. Nucleic Acids Res (2014) 0.96
High-throughput, sensitive quantification of repopulating hematopoietic stem cell clones. J Virol (2010) 0.95
Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples. Hum Gene Ther Methods (2013) 0.95
Contributions of gene marking to cell and gene therapies. Hum Gene Ther (2011) 0.95
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases. Cell Stem Cell (2016) 0.93
Lentiviral and targeted cellular barcoding reveals ongoing clonal dynamics of cell lines in vitro and in vivo. Genome Biol (2014) 0.92
Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence. Nucleic Acids Res (2014) 0.90
A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues. J R Soc Interface (2013) 0.87
Quantitative shearing linear amplification polymerase chain reaction: an improved method for quantifying lentiviral vector insertion sites in transplanted hematopoietic cell systems. Hum Gene Ther Methods (2015) 0.85
Using TRIP for genome-wide position effect analysis in cultured cells. Nat Protoc (2014) 0.85
Building a lineage from single cells: genetic techniques for cell lineage tracking. Nat Rev Genet (2017) 0.83
Molecular neuroanatomy: a generation of progress. Trends Neurosci (2013) 0.83
DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts. Nat Commun (2014) 0.83
Human miR223 promoter as a novel myelo-specific promoter for chronic granulomatous disease gene therapy. Hum Gene Ther Methods (2013) 0.82
Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus. Proc Natl Acad Sci U S A (2015) 0.79
Long-term evolution is surprisingly predictable in lattice proteins. J R Soc Interface (2013) 0.78
Limitations and challenges of genetic barcode quantification. Sci Rep (2017) 0.78
Mechanisms of blood homeostasis: lineage tracking and a neutral model of cell populations in rhesus macaques. BMC Biol (2015) 0.77
Tracing dynamics and clonal heterogeneity of Cbx7-induced leukemic stem cells by cellular barcoding. Stem Cell Reports (2014) 0.77
Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications. Stem Cells Int (2015) 0.77
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion. Mol Cancer (2017) 0.76
Long-term in vitro maintenance of clonal abundance and leukaemia-initiating potential in acute lymphoblastic leukaemia. Leukemia (2016) 0.76
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell (2017) 0.76
Site-specific recombinatorics: in situ cellular barcoding with the Cre Lox system. BMC Syst Biol (2016) 0.75
Stem and progenitor cell subsets are affected by JAK2 signaling and can be monitored by flow cytometry. PLoS One (2014) 0.75
Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique. Open Biol (2017) 0.75
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells (2016) 0.75
Quantitative Stability of Hematopoietic Stem and Progenitor Cell Clonal Output in Transplanted Rhesus Macaques. Blood (2017) 0.75
Lentiviral Fluorescent Genetic Barcoding for Multiplex Fate Tracking of Leukemic Cells. Mol Ther Methods Clin Dev (2017) 0.75
What do we know about the participation of hematopoietic stem cells in hematopoiesis? F1000Res (2015) 0.75
Unperturbed vs. post-transplantation hematopoiesis: both in vivo but different. Curr Opin Hematol (2016) 0.75
Genetic barcode sequencing for screening altered population dynamics of hematopoietic stem cells transduced with lentivirus. Mol Ther Methods Clin Dev (2014) 0.75
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo. Nature (2017) 0.75
Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia. Leukemia (2017) 0.75
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood (2005) 2.99
The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood (2005) 2.79
Rescue of salivary gland function after stem cell transplantation in irradiated glands. PLoS One (2008) 2.70
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
The ageing haematopoietic stem cell compartment. Nat Rev Immunol (2013) 2.15
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. J Exp Med (2011) 1.95
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
A Limited role for p21Cip1/Waf1 in maintaining normal hematopoietic stem cell functioning. Stem Cells (2006) 1.84
Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics. Exp Hematol (2003) 1.69
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties. Proc Natl Acad Sci U S A (2007) 1.68
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells. Blood (2008) 1.67
In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1. Dev Cell (2003) 1.53
Asymmetry in skeletal distribution of mouse hematopoietic stem cell clones and their equilibration by mobilizing cytokines. J Exp Med (2014) 1.52
Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway. Clin Cancer Res (2008) 1.45
Engraftment of syngeneic bone marrow is not more efficient after intrafemoral transplantation than after traditional intravenous administration. Exp Hematol (2010) 1.44
Growth factor treatment prior to low-dose total body irradiation increases donor cell engraftment after bone marrow transplantation in mice. Blood (2002) 1.38
Counting stem cells: methodological constraints. Nat Methods (2012) 1.35
Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging. Stem Cells (2005) 1.35
Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis. Hippocampus (2009) 1.29
Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool. Stem Cells (2008) 1.26
Hematopoietic stem cell expansion: challenges and opportunities. Ann N Y Acad Sci (2012) 1.25
A statistical multiprobe model for analyzing cis and trans genes in genetical genomics experiments with short-oligonucleotide arrays. Genetics (2005) 1.25
Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. Blood (2009) 1.24
Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood (2013) 1.23
Characterization of mouse hematopoietic stem and progenitor cells. Curr Protoc Immunol (2008) 1.21
Chromosomal macrodomains and associated proteins: implications for DNA organization and replication in gram negative bacteria. PLoS Genet (2011) 1.20
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol (2013) 1.16
A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood (2002) 1.13
Cellular memory and hematopoietic stem cell aging. Stem Cells (2006) 1.10
Hematopoietic stem cell aging and self-renewal. Cell Tissue Res (2007) 1.10
Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1. Blood (2007) 1.08
Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells. Blood (2011) 1.07
Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche? Hum Mol Genet (2006) 1.07
BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells. Blood (2010) 1.06
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status. Blood (2004) 1.06
Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone. Haematologica (2012) 1.05
Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL. Blood (2006) 1.05
Fibroblast growth factors as regulators of stem cell self-renewal and aging. Mech Ageing Dev (2006) 1.01
Selective expression of cholesterol metabolism genes in normal CD34+CD38- cells with a heterogeneous expression pattern in AML cells. Exp Hematol (2006) 1.00
Hippocampal cell proliferation across the day: increase by running wheel activity, but no effect of sleep and wakefulness. Behav Brain Res (2005) 1.00
Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization. Blood (2004) 1.00
Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects? Curr Opin Immunol (2011) 0.99
Fibroblast growth factor-1 and -2 preserve long-term repopulating ability of hematopoietic stem cells in serum-free cultures. Stem Cells (2006) 0.99
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia. J Biol Chem (2007) 0.98
In vitro assays for cobblestone area-forming cells, LTC-IC, and CFU-C. Methods Mol Biol (2008) 0.97
Stem cell assays: something old, something new, something borrowed. Stem Cells (2004) 0.96
Undifferentiated embryonic cell transcription factor 1 regulates ESC chromatin organization and gene expression. Stem Cells (2010) 0.95
Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation. Clin Cancer Res (2008) 0.94
Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases. Atherosclerosis (2010) 0.94
Levenshtein error-correcting barcodes for multiplexed DNA sequencing. BMC Bioinformatics (2013) 0.91
Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny. Immunogenetics (2008) 0.90
Enhancing the detection of barcoded reads in high throughput DNA sequencing data by controlling the false discovery rate. BMC Bioinformatics (2014) 0.87
Chemotherapy prior to autologous bone marrow transplantation impairs long-term engraftment in mice. Exp Hematol (2003) 0.84
Cerebellar heterokaryon formation increases with age and after irradiation. Stem Cell Res (2008) 0.83
Polycomb group proteins in hematopoietic stem cell aging and malignancies. Int J Hematol (2011) 0.83
Inferring combinatorial association logic networks in multimodal genome-wide screens. Bioinformatics (2010) 0.82
Isolation and assessment of long-term reconstituting hematopoietic stem cells from adult mouse bone marrow. Curr Protoc Stem Cell Biol (2007) 0.82
Administration of low-dose cytarabine results in immediate S-phase arrest and subsequent activation of cell cycling in murine stem cells. Exp Hematol (2005) 0.82
The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation. Blood (2012) 0.81
Hematopoietic stem cell quiescence: yet another role for p53. Cell Stem Cell (2009) 0.81
Latexin is a newly discovered regulator of hematopoietic stem cells. Nat Genet (2007) 0.80
Progress and obstacles towards generating hematopoietic stem cells from pluripotent stem cells. Curr Opin Hematol (2015) 0.80
Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia. Haematologica (2009) 0.78
Identification of quantitative trait loci regulating haematopoietic parameters in B6AKRF2 mice. Br J Haematol (2006) 0.78
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, human and rat. BMC Bioinformatics (2007) 0.77
Shared Ageing Research Models (ShARM): a new facility to support ageing research. Biogerontology (2013) 0.77
Noncanonical Wnt comes of age in hematopoietic stem cells. Cell Stem Cell (2013) 0.76
Sca-1 is an early-response target of histone deacetylase inhibitors and marks hematopoietic cells with enhanced function. Exp Hematol (2012) 0.76
Stem Cells and Aging: What's Next? Cell Stem Cell (2015) 0.75
A novel growth factor encoded by an old gene. Haematologica (2005) 0.75
The balance among immune suppression, stem cell ablation, competition, and engraftment. Blood (2004) 0.75
Barcoded vector libraries and retroviral or lentiviral barcoding of hematopoietic stem cells. Methods Mol Biol (2014) 0.75