Published in Can J Neurol Sci on August 01, 2004
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Frataxin gene point mutations in Italian Friedreich ataxia patients. Neurogenetics (2007) 1.00
The differential diagnosis of Huntington's disease-like syndromes: 'red flags' for the clinician. J Neurol Neurosurg Psychiatry (2012) 0.86
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International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol Rev (2005) 5.25
Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and II experience. Pediatr Blood Cancer (2008) 2.50
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception. EMBO J (2004) 2.15
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma. J Clin Oncol (2012) 1.88
A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia. Curr Biol (2007) 1.70
Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels. Mol Pharmacol (2008) 1.63
Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons. Proc Natl Acad Sci U S A (2006) 1.62
The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. J Neurosci (2004) 1.57
Ca(V)3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons. Eur J Neurosci (2006) 1.48
International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels. Pharmacol Rev (2003) 1.43
De-escalation of therapy for pediatric medulloblastoma: trade-offs between quality of life and survival. Pediatr Blood Cancer (2014) 1.39
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures. Sci Transl Med (2012) 1.39
UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants. Curr Biol (2007) 1.36
Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. J Neurosci (2009) 1.36
Role of voltage-gated calcium channels in ascending pain pathways. Brain Res Rev (2008) 1.35
Distinctive clinical course and pattern of relapse in adolescents with medulloblastoma. Int J Radiat Oncol Biol Phys (2005) 1.24
A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours. Eur J Cancer (2009) 1.24
Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue. Pediatr Blood Cancer (2007) 1.21
Contributions of T-type calcium channel isoforms to neuronal firing. Channels (Austin) (2010) 1.20
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy. J Neurosci (2009) 1.20
Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci (2007) 1.14
Differential inhibition of T-type calcium channels by neuroleptics. J Neurosci (2002) 1.11
The C. elegans T-type calcium channel CCA-1 boosts neuromuscular transmission. J Exp Biol (2005) 1.11
Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties. J Neurosci (2003) 1.11
Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children. Cancer Res (2013) 1.10
T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome. Proc Natl Acad Sci U S A (2011) 1.06
Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies. Channels (Austin) (2009) 1.05
Tenascin-C promotes microvascular cell migration and phosphorylation of focal adhesion kinase. Cancer Res (2002) 1.04
Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy. J Biol Chem (2004) 1.03
Pseudomigraine with lymphocytic pleocytosis: a calcium channelopathy? Clinical description of 10 cases and genetic analysis of the familial hemiplegic migraine gene CACNA1A. Headache (2003) 1.03
Cerebello-thalamo-cerebral connections in pediatric brain tumor patients: impact on working memory. Neuroimage (2011) 1.02
Clinical and neuroanatomical predictors of cerebellar mutism syndrome. Neuro Oncol (2012) 0.99
Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy. Ann Neurol (2005) 0.97
Medulloblastoma in the second decade of life: a specific group with respect to toxicity and management: a Canadian Pediatric Brain Tumor Consortium Study. Cancer (2005) 0.96
T-type calcium channels in burst-firing, network synchrony, and epilepsy. Biochim Biophys Acta (2012) 0.96
Splice-variant changes of the Ca(V)3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development. Channels (Austin) (2010) 0.95
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker. J Pharmacol Exp Ther (2010) 0.94
Contribution of calcium-dependent facilitation to synaptic plasticity revealed by migraine mutations in the P/Q-type calcium channel. Proc Natl Acad Sci U S A (2010) 0.93
A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement. J Neurosci (2008) 0.93
Voltage-gated calcium channels and disease. Biofactors (2011) 0.91
Intracystic treatments for craniopharyngioma. Neurosurg Focus (2010) 0.90
Carboplatin hypersensitivity reaction in pediatric patients with low-grade glioma: a Canadian Pediatric Brain Tumor Consortium experience. Cancer (2008) 0.89
A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma. Eur J Cancer (2010) 0.89
Low threshold T-type calcium channels as targets for novel epilepsy treatments. Br J Clin Pharmacol (2014) 0.89
A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain. Pain (2011) 0.88
Contributions of T-type voltage-gated calcium channels to postsynaptic calcium signaling within Purkinje neurons. Cerebellum (2012) 0.88
Novel Mutations in FA2H-Associated Neurodegeneration: An Underrecognized Condition? J Child Neurol (2012) 0.88
Multimodality therapy for CNS mixed malignant germ cell tumors (MMGCT): results of a phase II multi-institutional study. J Neurooncol (2014) 0.88
Functional implications of a novel EA2 mutation in the P/Q-type calcium channel. Ann Neurol (2004) 0.87
Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors. J Biol Chem (2007) 0.87
Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. J Pharmacol Exp Ther (2003) 0.86
Symptomatic dystrophinopathies in female children. Neuromuscul Disord (2010) 0.86
Scaffold-based design and synthesis of potent N-type calcium channel blockers. Bioorg Med Chem Lett (2009) 0.86
Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy. Epilepsia (2006) 0.86
EZH2 expression is a prognostic factor in childhood intracranial ependymoma: a Canadian Pediatric Brain Tumor Consortium study. Cancer (2015) 0.85
The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience. Childs Nerv Syst (2014) 0.84
Modulation of low-voltage-activated T-type Ca²⁺ channels. Biochim Biophys Acta (2012) 0.83
Pleomorphic xanthoastrocytoma of the spinal cord: case report and literature review. Clin Neuropathol (2014) 0.82
A fluorescence-based high-throughput screening assay for the identification of T-type calcium channel blockers. Assay Drug Dev Technol (2009) 0.81
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels. Mol Pharmacol (2011) 0.81
Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6. J Pharmacol Exp Ther (2005) 0.81
Block of voltage-gated calcium channels stimulates dopamine efflux in rat mesocorticolimbic system. Neuropharmacology (2009) 0.81
Late mortality in pediatric patients with craniopharyngioma. J Neurooncol (2010) 0.81
Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. Bioorg Med Chem Lett (2012) 0.81
Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons. Mol Pain (2011) 0.80
Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy. Pflugers Arch (2014) 0.80
Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors. Bioorg Med Chem Lett (2010) 0.80
Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans. PLoS Genet (2012) 0.79
Modular, efficient synthesis of asymmetrically substituted piperazine scaffolds as potent calcium channel blockers. Bioorg Med Chem Lett (2013) 0.79
Atypical teratoid rhabdoid tumors (ATRTs): the British Columbia's Children's Hospital's experience, 1986-2006. Brain Pathol (2012) 0.79
Advances in voltage-gated calcium channel structure, function and physiology. Biochim Biophys Acta (2013) 0.77
Optic pathway gliomas in adolescence--time to challenge treatment choices? Neuro Oncol (2013) 0.77
Outcome of secondary high-grade glioma in children previously treated for a malignant condition: a study of the Canadian Pediatric Brain Tumour Consortium. Radiother Oncol (2006) 0.77
Treatments for neuropathic pain differentially affect delayed matching accuracy by macaques: effects of amitriptyline and gabapentin. Pain (2010) 0.76
Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels. J Neurochem (2011) 0.76
Growing teratoma syndrome in intracranial non-germinomatous germ cell tumors (iNGGCTs): a risk for secondary malignant transformation—a report of two cases. Childs Nerv Syst (2014) 0.76
Modulating modulation: crosstalk between regulatory pathways of presynaptic calcium channels. Mol Interv (2002) 0.76
The unusual suspects: Regulation of retinal calcium channels by somatostatin. Channels (Austin) (2015) 0.75
Late effects in survivors of childhood CNS tumors treated on Head Start I and II protocols. Pediatr Blood Cancer (2014) 0.75
Occurrence of basal ganglia germ cell tumors without a mass. Arch Neurol (2009) 0.75
Intracranial tumors in infants: long-term functional outcome, survival, and its predictors. Childs Nerv Syst (2012) 0.75