Published in Circulation on September 21, 2004
Atrial fibrosis and the mechanisms of atrial fibrillation. Heart Rhythm (2006) 1.86
Atrial cellular electrophysiological changes in patients with ventricular dysfunction may predispose to AF. Heart Rhythm (2008) 1.72
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest (2013) 1.49
Cellular bases for human atrial fibrillation. Heart Rhythm (2008) 1.25
Mechanistic inquiry into the role of tissue remodeling in fibrotic lesions in human atrial fibrillation. Biophys J (2013) 1.14
Atrial fibrillation: basic mechanisms, remodeling and triggers. J Interv Card Electrophysiol (2005) 1.05
Chronic heart failure and the substrate for atrial fibrillation. Cardiovasc Res (2009) 1.05
Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.92
Perturbed atrial calcium handling in an ovine model of heart failure: potential roles for reductions in the L-type calcium current. J Mol Cell Cardiol (2014) 0.86
Atrial tachycardia induces remodelling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes. Br J Pharmacol (2007) 0.85
An emerging role for the miR-26 family in cardiovascular disease. Trends Cardiovasc Med (2014) 0.84
Atrial fibrillation complicated by heart failure induces distinct remodeling of calcium cycling proteins. PLoS One (2015) 0.79
Information learned from animal models of atrial fibrillation. Cardiol Clin (2009) 0.79
An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure. Exp Ther Med (2013) 0.79
Effects of selective mineralocorticoid receptor antagonism on atrial ion currents and early ionic tachycardia-induced electrical remodelling in rabbits. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
Differential expression of potassium channels and abnormal conduction in experimental tachycardia-induced heart failure. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.78
Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models. PLoS Comput Biol (2016) 0.77
Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.75
Mathematical models of canine right and left atria cardiomyocytes. J Zhejiang Univ Sci B (2010) 0.75
Relaxin Level in Patients With Atrial Fibrillation and Association with Heart Failure Occurrence: A STROBE Compliant Article. Medicine (Baltimore) (2016) 0.75
Improving Atrial Fibrillation Therapy: Is There a Gene for That? J Am Coll Cardiol (2017) 0.75
[Rate versus rhythm control with and without heart failure]. Herz (2008) 0.75
Rhythm control versus rate control for atrial fibrillation and heart failure. N Engl J Med (2008) 6.17
MicroRNA-34a regulates cardiac ageing and function. Nature (2013) 4.03
Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation. J Am Coll Cardiol (2008) 4.01
Cardiac arrhythmogenic remodeling in a rat model of long-term intensive exercise training. Circulation (2010) 3.72
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Long-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device: implications for optimal patient care. J Am Coll Cardiol (2004) 3.50
Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nat Med (2012) 3.34
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 3.12
Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control. Can J Cardiol (2012) 2.96
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J Physiol (2007) 2.83
Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer (2009) 2.64
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation (2012) 2.58
Recent advances in the molecular pathophysiology of atrial fibrillation. J Clin Invest (2011) 2.38
Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model. J Am Coll Cardiol (2013) 2.38
Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure. Circ Arrhythm Electrophysiol (2008) 2.37
Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve. Circulation (2008) 2.34
Tumor exosomes inhibit differentiation of bone marrow dendritic cells. J Immunol (2007) 2.16
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol (2012) 2.08
The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circ Res (2014) 2.07
Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure. Cardiovasc Res (2004) 2.06
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model. Cardiovasc Res (2005) 2.02
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure. Cardiovasc Res (2007) 2.02
Atrial fibrillation pathophysiology: implications for management. Circulation (2011) 2.01
Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function. Circ Res (2002) 2.00
Transmural action potential and ionic current remodeling in ventricles of failing canine hearts. Am J Physiol Heart Circ Physiol (2002) 2.00
Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation. Biophys J (2005) 1.96
Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation. Circulation (2003) 1.86
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. J Mol Cell Cardiol (2007) 1.85
Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation. Circulation (2012) 1.81
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes Dev (2006) 1.80
Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation. Cardiovasc Res (2010) 1.74
Thymus exosomes-like particles induce regulatory T cells. J Immunol (2008) 1.73
External cardioversion of atrial fibrillation in patients with implanted pacemaker or cardioverter-defibrillator systems: a randomized comparison of monophasic and biphasic shock energy application. Eur Heart J (2007) 1.72
Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure. Heart Rhythm (2007) 1.71
Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence. Eur Heart J (2005) 1.71
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. J Am Coll Cardiol (2013) 1.68
Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy. Circ Res (2014) 1.68
Pulmonary vein reentry--properties and size matter: insights from a computational analysis. Heart Rhythm (2007) 1.68
Improved outcome following restoration of sinus rhythm prior to catheter ablation of persistent atrial fibrillation: a comparative multicenter study. Heart Rhythm (2012) 1.67
Biomedical applications of graphene. Theranostics (2012) 1.67
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation. Circulation (2005) 1.67
Substrate size as a determinant of fibrillatory activity maintenance in a mathematical model of canine atrium. Am J Physiol Heart Circ Physiol (2005) 1.65
New antiarrhythmic drugs for treatment of atrial fibrillation. Lancet (2010) 1.65
Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure. Circulation (2004) 1.64
Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences. Circulation (2008) 1.61
Determinants of atrial fibrillation in an animal model of obesity and acute obstructive sleep apnea. Heart Rhythm (2012) 1.59
Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. Heart Rhythm (2010) 1.59
Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm. Circulation (2011) 1.58
A proposal for new clinical concepts in the management of atrial fibrillation. Am Heart J (2012) 1.57
In vivo electrophysiological effects of a selective slow delayed-rectifier potassium channel blocker in anesthetized dogs: potential insights into class III actions. Cardiovasc Res (2004) 1.55
Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol (2010) 1.55
Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization. Cardiovasc Res (2005) 1.54
Cholinergic atrial fibrillation in a computer model of a two-dimensional sheet of canine atrial cells with realistic ionic properties. Circ Res (2002) 1.54
Dronedarone: an emerging agent with rhythm- and rate-controlling effects. J Cardiovasc Electrophysiol (2006) 1.54
Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation. Heart Rhythm (2009) 1.54
Differences in atrial fibrillation properties under vagal nerve stimulation versus atrial tachycardia remodeling. Heart Rhythm (2009) 1.53
Molecular basis of funny current (If) in normal and failing human heart. J Mol Cell Cardiol (2008) 1.53
Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog. Circulation (2013) 1.51
Atrial fibrillation-associated remodeling does not promote atrial thrombus formation in canine models. Circ Arrhythm Electrophysiol (2012) 1.50
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest (2013) 1.49
Homogeneous gold-catalyzed oxidative carboheterofunctionalization of alkenes. J Am Chem Soc (2010) 1.49
Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation. Circ Arrhythm Electrophysiol (2010) 1.49
Involvement of lipid rafts and caveolae in cardiac ion channel function. Cardiovasc Res (2006) 1.48
Region-specific gene expression profiles in the left atria of patients with valvular atrial fibrillation. Heart Rhythm (2012) 1.47
Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression. Circ Res (2014) 1.47
Differential effectiveness of pharmacological strategies to reveal dormant pulmonary vein conduction: a clinical-experimental correlation. Heart Rhythm (2011) 1.45
Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties. J Physiol (2003) 1.45
Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice. Cardiovasc Res (2011) 1.44
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts. J Physiol (2004) 1.44
Cellular properties of C-terminal KCNH2 long QT syndrome mutations: description and divergence from clinical phenotypes. Heart Rhythm (2008) 1.43
HERG K+ channel, a regulator of tumor cell apoptosis and proliferation. Cancer Res (2002) 1.43
Novel molecular targets for atrial fibrillation therapy. Nat Rev Drug Discov (2012) 1.42
Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs. Circulation (2004) 1.41
Alkynes as equivalents of alpha-diazo ketones in generating alpha-oxo metal carbenes: a gold-catalyzed expedient synthesis of dihydrofuran-3-ones. J Am Chem Soc (2010) 1.41
Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle. Circ Res (2002) 1.41
Malignant Osborn waves during therapeutic hypothermia. Europace (2009) 1.38
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts. J Mol Cell Cardiol (2010) 1.37
A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death. J Immunol (2006) 1.36
A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link? J Physiol (2002) 1.35
Gold-catalyzed highly regioselective oxidation of C-C triple bonds without acid additives: propargyl moieties as masked α,β-unsaturated carbonyls. J Am Chem Soc (2010) 1.33
Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology (2009) 1.33
MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation. Circulation (2013) 1.33
Novel approaches for pharmacological management of atrial fibrillation. Drugs (2009) 1.32
Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols. J Am Chem Soc (2010) 1.31
Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs. Circulation (2002) 1.31
A two-step, formal [4 + 2] approach toward piperidin-4-ones via Au catalysis. J Am Chem Soc (2009) 1.30
Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia. Circulation (2008) 1.30
Changes in connexin expression and the atrial fibrillation substrate in congestive heart failure. Circ Res (2009) 1.29
Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes. Circulation (2006) 1.27
G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function. J Physiol (2011) 1.27
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current. Circ Res (2008) 1.27
A flexible and stereoselective synthesis of azetidin-3-ones through gold-catalyzed intermolecular oxidation of alkynes. Angew Chem Int Ed Engl (2011) 1.27