Published in Circ Arrhythm Electrophysiol on July 24, 2010
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation (2012) 2.58
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol (2012) 2.08
Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation. Circ Res (2011) 1.82
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation (2013) 1.69
Oxidized CaMKII causes cardiac sinus node dysfunction in mice. J Clin Invest (2011) 1.68
Rotors and the dynamics of cardiac fibrillation. Circ Res (2013) 1.58
Novel molecular targets for atrial fibrillation therapy. Nat Rev Drug Discov (2012) 1.42
Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation (2013) 1.29
Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation. J Am Coll Cardiol (2012) 1.27
Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts. Eur Heart J (2015) 1.21
Déjà vu in the theories of atrial fibrillation dynamics. Cardiovasc Res (2010) 1.15
Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue. PLoS One (2011) 1.15
Long-term frequency gradients during persistent atrial fibrillation in sheep are associated with stable sources in the left atrium. Circ Arrhythm Electrophysiol (2012) 1.12
Whole genome expression differences in human left and right atria ascertained by RNA sequencing. Circ Cardiovasc Genet (2012) 1.12
Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol (2013) 1.11
Dominant frequency increase rate predicts transition from paroxysmal to long-term persistent atrial fibrillation. Circulation (2014) 1.07
The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications. Cardiovasc Res (2010) 1.05
Effects of electrical and structural remodeling on atrial fibrillation maintenance: a simulation study. PLoS Comput Biol (2012) 0.98
Genetic defects in the hotspot of inwardly rectifying K(+) (Kir) channels and their metabolic consequences: a review. Mol Genet Metab (2011) 0.95
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EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implication. J Arrhythm (2016) 0.94
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Spatial gradients in action potential duration created by regional magnetofection of hERG are a substrate for wavebreak and turbulent propagation in cardiomyocyte monolayers. J Physiol (2012) 0.89
Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation. Nat Rev Cardiol (2016) 0.83
Ion Channels in the Heart. Compr Physiol (2015) 0.83
Isolation of human atrial myocytes for simultaneous measurements of Ca2+ transients and membrane currents. J Vis Exp (2013) 0.83
Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels. Cardiovasc Res (2016) 0.82
Improved understanding of the pathophysiology of atrial fibrillation through the lens of discrete pathological pathways. Glob Cardiol Sci Pract (2014) 0.80
Presence and stability of rotors in atrial fibrillation: evidence and therapeutic implications. Cardiovasc Res (2016) 0.79
Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia. Front Physiol (2012) 0.79
Human atrial fibrillation: insights from computational electrophysiological models. Trends Cardiovasc Med (2011) 0.79
Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis. Arrhythm Electrophysiol Rev (2016) 0.78
Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res Cardiol (2015) 0.78
Translational research in atrial fibrillation: a quest for mechanistically based diagnosis and therapy. Circ Arrhythm Electrophysiol (2012) 0.78
Expression profile analysis of circulating microRNAs and their effects on ion channels in Chinese atrial fibrillation patients. Int J Clin Exp Med (2015) 0.78
NOS1AP modulates intracellular Ca(2+) in cardiac myocytes and is up-regulated in dystrophic cardiomyopathy. Int J Physiol Pathophysiol Pharmacol (2014) 0.78
Effect of ethanol at clinically relevant concentrations on atrial inward rectifier potassium current sensitive to acetylcholine. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.77
The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in dedicated goat and dog models. Br J Pharmacol (2017) 0.76
Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.76
Polyunsaturated Fatty acids in atrial fibrillation: looking for the proper candidates. Front Physiol (2012) 0.75
In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias. Br J Pharmacol (2016) 0.75
Voltage-dependent open-channel block of G protein-gated inward-rectifying K(+) (GIRK) current in rat atrial myocytes by tamoxifen. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.75
Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes. JACC Basic Transl Sci (2016) 0.75
STRUCTURAL AND FUNCTIONAL BASES OF CARDIAC FIBRILLATION. DIFFERENCES AND SIMILARITIES BETWEEN ATRIA AND VENTRICLES. JACC Clin Electrophysiol (2016) 0.75
Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization. Pharmacol Ther (2016) 0.75
Ionic and substrate mechanism of atrial fibrillation: rotors and the exitación frequency approach. Arch Cardiol Mex (2010) 0.75
Nicotine at clinically relevant concentrations affects atrial inward rectifier potassium current sensitive to acetylcholine. Naunyn Schmiedebergs Arch Pharmacol (2017) 0.75
Rhythm control versus rate control for atrial fibrillation and heart failure. N Engl J Med (2008) 6.17
Inflammation as a risk factor for atrial fibrillation. Circulation (2003) 4.95
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation. J Am Coll Cardiol (2008) 4.01
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Cardiac arrhythmogenic remodeling in a rat model of long-term intensive exercise training. Circulation (2010) 3.72
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice. J Clin Invest (2009) 3.45
Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle. Circulation (2005) 3.31
Atrial remodeling and atrial fibrillation: mechanisms and implications. Circ Arrhythm Electrophysiol (2008) 3.26
Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation. PLoS Comput Biol (2011) 3.21
Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control. Can J Cardiol (2012) 2.96
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J Physiol (2007) 2.83
A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells. J Mol Cell Cardiol (2012) 2.71
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation (2012) 2.58
The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management. Europace (2009) 2.52
Recent advances in the molecular pathophysiology of atrial fibrillation. J Clin Invest (2011) 2.38
Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model. J Am Coll Cardiol (2013) 2.38
Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure. Circ Arrhythm Electrophysiol (2008) 2.37
Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve. Circulation (2008) 2.34
Early detection of mechanical valve dysfunction using a new home monitoring device. Ann Thorac Surg (2007) 2.18
Defective cardiac ryanodine receptor regulation during atrial fibrillation. Circulation (2005) 2.15
Is repeated administration of blood-cardioplegia really necessary? Interact Cardiovasc Thorac Surg (2009) 2.10
Chronic vagus nerve stimulation improves autonomic control and attenuates systemic inflammation and heart failure progression in a canine high-rate pacing model. Circ Heart Fail (2009) 2.09
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol (2012) 2.08
The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circ Res (2014) 2.07
Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure. Cardiovasc Res (2004) 2.06
Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation. Heart Rhythm (2008) 2.05
Isolated aortic valve replacement in patients with small aortic annulus-a high-risk group on long-term follow-up. Thorac Cardiovasc Surg (2012) 2.04
Mechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo. Cardiovasc Res (2004) 2.04
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model. Cardiovasc Res (2005) 2.02
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure. Cardiovasc Res (2007) 2.02
Atrial fibrillation pathophysiology: implications for management. Circulation (2011) 2.01
Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function. Circ Res (2002) 2.00
Transmural action potential and ionic current remodeling in ventricles of failing canine hearts. Am J Physiol Heart Circ Physiol (2002) 2.00
Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation. Circulation (2006) 2.00
Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation. Biophys J (2005) 1.96
Outcome parameters for trials in atrial fibrillation: executive summary. Eur Heart J (2007) 1.90
Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation. Circulation (2003) 1.86
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. J Mol Cell Cardiol (2007) 1.85
Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation. Circ Res (2011) 1.82
Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation. Circulation (2012) 1.81
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes Dev (2006) 1.80
Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation. Circulation (2004) 1.77
Surgery for atrial fibrillation in patients with mitral valve disease: results at five years from the International Registry of Atrial Fibrillation Surgery. J Thorac Cardiovasc Surg (2008) 1.76
Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation. Cardiovasc Res (2010) 1.74
Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure. Heart Rhythm (2007) 1.71
Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence. Eur Heart J (2005) 1.71
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation. Ann Thorac Surg (2006) 1.71
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. J Am Coll Cardiol (2013) 1.68
Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy. Circ Res (2014) 1.68
Pulmonary vein reentry--properties and size matter: insights from a computational analysis. Heart Rhythm (2007) 1.68
Oxidized CaMKII causes cardiac sinus node dysfunction in mice. J Clin Invest (2011) 1.68
Improved outcome following restoration of sinus rhythm prior to catheter ablation of persistent atrial fibrillation: a comparative multicenter study. Heart Rhythm (2012) 1.67
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation. Circulation (2005) 1.67
Substrate size as a determinant of fibrillatory activity maintenance in a mathematical model of canine atrium. Am J Physiol Heart Circ Physiol (2005) 1.65
New antiarrhythmic drugs for treatment of atrial fibrillation. Lancet (2010) 1.65
Transapical transcatheter valve-in-valve implantation for deteriorated mitral valve bioprostheses. Ann Thorac Surg (2012) 1.64
Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure. Circulation (2004) 1.64
Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts. Cardiovasc Res (2006) 1.62
A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis. Biophys J (2011) 1.62
L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages. Circ Res (2009) 1.62
Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences. Circulation (2008) 1.61
Determinants of atrial fibrillation in an animal model of obesity and acute obstructive sleep apnea. Heart Rhythm (2012) 1.59
Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. Heart Rhythm (2010) 1.59
Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm. Circulation (2011) 1.58
Adipocyte fatty acid-binding protein suppresses cardiomyocyte contraction: a new link between obesity and heart disease. Circ Res (2009) 1.58
A proposal for new clinical concepts in the management of atrial fibrillation. Am Heart J (2012) 1.57
In vivo electrophysiological effects of a selective slow delayed-rectifier potassium channel blocker in anesthetized dogs: potential insights into class III actions. Cardiovasc Res (2004) 1.55
Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol (2010) 1.55
Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization. Cardiovasc Res (2005) 1.54
Cholinergic atrial fibrillation in a computer model of a two-dimensional sheet of canine atrial cells with realistic ionic properties. Circ Res (2002) 1.54