Published in J Biol Chem on September 21, 2004
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet (2007) 4.58
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
RNA interference in protozoan parasites: achievements and challenges. Eukaryot Cell (2011) 1.42
A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii. PLoS Pathog (2010) 1.27
Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution. Biol Direct (2010) 1.26
An unusual Dicer-like1 protein fuels the RNA interference pathway in Trypanosoma brucei. RNA (2006) 1.25
Comparative genomics: from genotype to disease phenotype in the leishmaniases. Int J Parasitol (2007) 1.09
UTP-dependent turnover of Trypanosoma brucei mitochondrial mRNA requires UTP polymerization and involves the RET1 TUTase. RNA (2005) 1.06
Functional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2. RNA (2006) 1.02
Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei. BMC Genomics (2012) 0.96
Expression site silencing and life-cycle progression appear normal in Argonaute1-deficient Trypanosoma brucei. Mol Biochem Parasitol (2006) 0.93
Selection and characterization of RNA interference-deficient trypanosomes impaired in target mRNA degradation. Eukaryot Cell (2004) 0.93
RNA interference in Trypanosoma brucei: role of the n-terminal RGG domain and the polyribosome association of argonaute. J Biol Chem (2009) 0.92
Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery. PLoS Pathog (2012) 0.91
The emerging world of small silencing RNAs in protozoan parasites. Trends Parasitol (2011) 0.91
Depletion of newly synthesized Argonaute1 impairs the RNAi response in Trypanosoma brucei. RNA (2007) 0.89
PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA. Cell Microbiol (2012) 0.87
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
RNA interference in protozoan parasites. Cell Microbiol (2004) 2.29
The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution. PLoS Pathog (2010) 2.15
Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein. Science (2012) 1.94
Argonaute protein in the early divergent eukaryote Trypanosoma brucei: control of small interfering RNA accumulation and retroposon transcript abundance. Mol Cell Biol (2004) 1.76
Golgi duplication in Trypanosoma brucei. J Cell Biol (2004) 1.75
Retention and loss of RNA interference pathways in trypanosomatid protozoans. PLoS Pathog (2010) 1.69
Disruption of Ixodes scapularis anticoagulation by using RNA interference. Proc Natl Acad Sci U S A (2004) 1.56
RNA interference in protozoan parasites: achievements and challenges. Eukaryot Cell (2011) 1.42
An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei. RNA (2003) 1.36
Functional characterization of a Trypanosoma brucei TATA-binding protein-related factor points to a universal regulator of transcription in trypanosomes. Mol Cell Biol (2004) 1.28
An unusual Dicer-like1 protein fuels the RNA interference pathway in Trypanosoma brucei. RNA (2006) 1.25
RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes. J Biol Chem (2002) 1.20
Small sense and antisense RNAs derived from a telomeric retroposon family in Giardia intestinalis. Eukaryot Cell (2005) 1.17
The sequence and analysis of Trypanosoma brucei chromosome II. Nucleic Acids Res (2003) 1.14
A PCR-based method for gene deletion and protein tagging in Trypanosoma brucei. Methods Mol Biol (2004) 1.12
Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei. Proc Natl Acad Sci U S A (2009) 1.11
On the role of exon and intron sequences in trans-splicing utilization and cap 4 modification of the trypanosomatid Leptomonas collosoma SL RNA. J Biol Chem (2002) 1.11
RNA interference: advances and questions. Philos Trans R Soc Lond B Biol Sci (2002) 1.06
Genomic rearrangements and transcriptional analysis of the spliced leader-associated retrotransposon in RNA interference-deficient Trypanosoma brucei. Mol Microbiol (2007) 1.04
Functional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2. RNA (2006) 1.02
Novel and essential subunits in the 300-kilodalton nuclear cap binding complex of Trypanosoma brucei. Mol Cell Biol (2005) 1.01
2'-O-methylation of position 2 of the trypanosome spliced leader cap 4 is mediated by a 48 kDa protein related to vaccinia virus VP39. Mol Biochem Parasitol (2006) 1.00
A protein related to the vaccinia virus cap-specific methyltransferase VP39 is involved in cap 4 modification in Trypanosoma brucei. RNA (2005) 0.99
Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei. BMC Genomics (2012) 0.96
Analysis of gene function in Trypanosoma brucei using RNA interference. Methods Mol Biol (2004) 0.95
Analysis of spliceosomal complexes in Trypanosoma brucei and silencing of two splicing factors Prp31 and Prp43. Mol Biochem Parasitol (2005) 0.94
Selection and characterization of RNA interference-deficient trypanosomes impaired in target mRNA degradation. Eukaryot Cell (2004) 0.93
The emerging role of RNA-binding proteins in the life cycle of Trypanosoma brucei. Cell Microbiol (2014) 0.93
RNA interference in Trypanosoma brucei: role of the n-terminal RGG domain and the polyribosome association of argonaute. J Biol Chem (2009) 0.92
The canonical pathway for selenocysteine insertion is dispensable in Trypanosomes. Proc Natl Acad Sci U S A (2009) 0.92
Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery. PLoS Pathog (2012) 0.91
The emerging world of small silencing RNAs in protozoan parasites. Trends Parasitol (2011) 0.91
Biochemical analysis of PIFTC3, the Trypanosoma brucei orthologue of nematode DYF-13, reveals interactions with established and putative intraflagellar transport components. Mol Microbiol (2010) 0.91
Depletion of newly synthesized Argonaute1 impairs the RNAi response in Trypanosoma brucei. RNA (2007) 0.89
In vivo analysis of the RNA interference mechanism in Trypanosoma brucei. Methods (2003) 0.87
Characterization of the Trypanosoma brucei cap hypermethylase Tgs1. Mol Biochem Parasitol (2007) 0.87
On the extent and role of the small proteome in the parasitic eukaryote Trypanosoma brucei. BMC Biol (2014) 0.87
Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA. Mol Biochem Parasitol (2007) 0.87
Small nucleolar RNA interference in Trypanosoma brucei: mechanism and utilization for elucidating the function of snoRNAs. Nucleic Acids Res (2010) 0.84
Downregulation of the essential Trypanosoma brucei La protein affects accumulation of elongator methionyl-tRNA. Mol Biochem Parasitol (2005) 0.84
The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway. Mol Microbiol (2012) 0.83
RNA-seq analysis of small RNPs in Trypanosoma brucei reveals a rich repertoire of non-coding RNAs. Nucleic Acids Res (2011) 0.82
Analysis of gene function in Trypanosoma brucei using RNA interference. Methods Mol Biol (2004) 0.81
Role of a 300-kilodalton nuclear complex in the maturation of Trypanosoma brucei initiator methionyl-tRNA. Eukaryot Cell (2004) 0.80
tRNASec is transcribed by RNA polymerase II in Trypanosoma brucei but not in humans. Nucleic Acids Res (2010) 0.80
A single-cloning-step procedure for the generation of RNAi plasmids producing long stem-loop RNA. Mol Biochem Parasitol (2012) 0.80
snoRNAs in Giardia lamblia: a novel role in RNA silencing? Trends Parasitol (2009) 0.79
Efficient transposition of preformed synaptic Tn5 complexes in Trypanosoma brucei. Mol Biochem Parasitol (2002) 0.78
Role of the Trypanosoma brucei HEN1 family methyltransferase in small interfering RNA modification. Eukaryot Cell (2013) 0.76
Repression of gene expression by the coliphage MS2 coat protein in Trypanosoma brucei. Mol Biochem Parasitol (2005) 0.76
Construction of Trypanosoma brucei Illumina RNA-Seq libraries enriched for transcript ends. Methods Mol Biol (2015) 0.75