Role of alginate in infection with mucoid Pseudomonas aeruginosa in cystic fibrosis.

PubWeight™: 1.97‹?› | Rank: Top 2%

🔗 View Article (PMC 463537)

Published in Thorax on January 01, 1992

Authors

S S Pedersen1, N Høiby, F Espersen, C Koch

Author Affiliations

1: Statens Seruminstitut, Department of Clinical Microbiology, Copenhagen, Denmark.

Articles citing this

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev (1996) 13.91

Lung infections associated with cystic fibrosis. Clin Microbiol Rev (2002) 9.20

Clinical significance of microbial infection and adaptation in cystic fibrosis. Clin Microbiol Rev (2011) 2.23

Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung. J Bacteriol (2009) 2.22

Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05

The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations. PLoS One (2012) 2.03

Pseudomonas biofilm matrix composition and niche biology. FEMS Microbiol Rev (2012) 2.00

Specific and rapid detection by fluorescent in situ hybridization of bacteria in clinical samples obtained from cystic fibrosis patients. J Clin Microbiol (2000) 1.91

Ciprofloxacin induction of a susceptibility determinant in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2005) 1.82

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients. Infect Immun (2007) 1.81

Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis. J Clin Microbiol (2004) 1.80

Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions. J Clin Invest (2006) 1.79

Role of alginate O acetylation in resistance of mucoid Pseudomonas aeruginosa to opsonic phagocytosis. Infect Immun (2001) 1.79

Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression. J Cyst Fibros (2008) 1.71

Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70

Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis (2005) 1.62

In vitro alginate polymerization and the functional role of Alg8 in alginate production by Pseudomonas aeruginosa. Appl Environ Microbiol (2006) 1.47

Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients. PLoS One (2010) 1.42

The Pseudomonas aeruginosa sensor kinase KinB negatively controls alginate production through AlgW-dependent MucA proteolysis. J Bacteriol (2009) 1.41

Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor. Infect Immun (2007) 1.30

Intrinsic and Extrinsic Regulation of Type III Secretion Gene Expression in Pseudomonas Aeruginosa. Front Microbiol (2011) 1.29

Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections. Proc Natl Acad Sci U S A (2000) 1.26

Identification of AlgR-regulated genes in Pseudomonas aeruginosa by use of microarray analysis. J Bacteriol (2004) 1.22

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa. MBio (2014) 1.16

Microbial pathogenesis in cystic fibrosis: pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Infect Immun (1998) 1.11

Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling. J Bacteriol (2010) 1.10

The transcriptional regulator AlgR is essential for Pseudomonas aeruginosa pathogenesis. Infect Immun (2002) 1.10

Lung infections. 3. Pseudomonas aeruginosa and other related species. Thorax (1998) 1.08

P-113D, an antimicrobial peptide active against Pseudomonas aeruginosa, retains activity in the presence of sputum from cystic fibrosis patients. Antimicrob Agents Chemother (2001) 1.08

Long-term follow up of changes in FEV1 and treatment intensity during Pseudomonas aeruginosa colonisation in patients with cystic fibrosis. Thorax (1998) 1.06

Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts. Proc Natl Acad Sci U S A (2013) 1.05

Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa. J Bacteriol (2005) 1.04

Dynamic remodeling of microbial biofilms by functionally distinct exopolysaccharides. MBio (2014) 1.03

Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. Infect Immun (1997) 1.02

Human immune response to Pseudomonas aeruginosa mucoid exopolysaccharide (alginate) vaccine. Infect Immun (1994) 1.01

The AlgZR two-component system recalibrates the RsmAYZ posttranscriptional regulatory system to inhibit expression of the Pseudomonas aeruginosa type III secretion system. J Bacteriol (2013) 0.96

Insights into the role of extracellular polysaccharides in Burkholderia adaptation to different environments. Front Cell Infect Microbiol (2011) 0.91

Impact of alginate overproduction on attachment and biofilm architecture of a supermucoid Pseudomonas aeruginosa strain. Appl Environ Microbiol (2009) 0.91

Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix. J Bacteriol (2005) 0.89

Vaccines for Pseudomonas aeruginosa: a long and winding road. Expert Rev Vaccines (2014) 0.89

Porins of Pseudomonas aeruginosa induce release of tumor necrosis factor alpha and interleukin-6 by human leukocytes. Infect Immun (1997) 0.88

Toll-like receptor 2 represses nonpilus adhesin-induced signaling in acute infections with the Pseudomonas aeruginosa pilA mutant. Infect Immun (2004) 0.87

Alginate Polymerization and Modification Are Linked in Pseudomonas aeruginosa. MBio (2015) 0.87

Tobramycin administered by the TOBI(®) Podhaler(®) for persons with cystic fibrosis: a review. Med Devices (Auckl) (2011) 0.86

Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils. Infect Immun (2015) 0.79

Construction and characterization of a highly redundant Pseudomonas aeruginosa genomic library prepared from 12 clinical isolates: application to studies of gene distribution among populations. Int J Pediatr Otorhinolaryngol (2006) 0.78

The Pseudomonas aeruginosa AlgZR two-component system coordinates multiple phenotypes. Front Cell Infect Microbiol (2014) 0.77

Effect of carbon on whole-biofilm metabolic response to high doses of streptomycin. Front Microbiol (2015) 0.76

Phenotypic and Genotypic Comparison of Epidemic and Non-Epidemic Strains of Pseudomonas aeruginosa from Individuals with Cystic Fibrosis. PLoS One (2015) 0.76

Multidimensional clinical phenotyping of an adult cystic fibrosis patient population. PLoS One (2015) 0.75

Evolutionary adaptations of biofilms infecting cystic fibrosis lungs promote mechanical toughness by adjusting polysaccharide production. NPJ Biofilms Microbiomes (2017) 0.75

Articles cited by this

Cystic fibrosis. Am Rev Respir Dis (1976) 6.62

Cystic fibrosis in adults. 75 cases and a review of 232 cases in the literature. Am J Med (1979) 3.54

Bacterial precipitins in serum of patients with cystic fibrosis. Lancet (1968) 3.29

Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta Paediatr Scand (1983) 3.13

Multiple of isolates of Pseudomonas aeruginosa with differing antimicrobial susceptibility patterns from patients with cystic fibrosis. J Infect Dis (1979) 3.02

Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic and prognostic significance of Pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis. Scand J Respir Dis (1977) 2.50

Pseudomonas aeruginosa infection in cystic fibrosis. Relationship between mucoid strains of Pseudomonas aeruginosa and the humoral immune response. Acta Pathol Microbiol Scand B Microbiol Immunol (1974) 2.46

Utilization of human respiratory secretions by mucoid Pseudomonas aeruginosa of cystic fibrosis origin. Infect Immun (1982) 2.32

Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa. J Pediatr (1990) 2.28

Respiratory infections in cystic fibrosis patients caused by virus, chlamydia and mycoplasma--possible synergism with Pseudomonas aeruginosa. Acta Paediatr Scand (1981) 2.03

Five- to seven-year course of pulmonary function in cystic fibrosis. Am Rev Respir Dis (1976) 2.03

Relation between tumor necrosis factor-alpha and granulocyte elastase-alpha 1-proteinase inhibitor complexes in the plasma of patients with cystic fibrosis. Am Rev Respir Dis (1989) 1.99

Pseudomonas aeruginosa: immune status in patients with cystic fibrosis. Infect Immun (1972) 1.99

Serotyping of Pseudomonas aeruginosa isolates from patients with cystic fibrosis of the pancreas. J Clin Microbiol (1975) 1.81

Polysaccharide surface antigens expressed by nonmucoid isolates of Pseudomonas aeruginosa from cystic fibrosis patients. J Clin Microbiol (1986) 1.76

The role of immune complexes in the pathogenesis of bacterial infections. Annu Rev Microbiol (1986) 1.67

Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical sites. J Clin Microbiol (1986) 1.60

Alginate biosynthetic enzymes in mucoid and nonmucoid Pseudomonas aeruginosa: overproduction of phosphomannose isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase by overexpression of the phosphomannose isomerase (pmi) gene. J Bacteriol (1987) 1.55

[Heights and weights of Danish children]. Ugeskr Laeger (1982) 1.50

Diagnosis of chronic Pseudomonas aeruginosa infection in cystic fibrosis by enzyme-linked immunosorbent assay. J Clin Microbiol (1987) 1.49

Serum immunoglobulin levels in cystic fibrosis. Am J Dis Child (1966) 1.30

Acute lung injury in rat caused by immunoglobulin A immune complexes. J Clin Invest (1984) 1.29

Alginate production by clinical nonmucoid Pseudomonas aeruginosa strains. J Clin Microbiol (1987) 1.28

Purification, characterization, and immunological cross-reactivity of alginates produced by mucoid Pseudomonas aeruginosa from patients with cystic fibrosis. J Clin Microbiol (1989) 1.28

Management of Pseudomonas aeruginosa lung infection in Danish cystic fibrosis patients. Acta Paediatr Scand (1987) 1.24

Immunoglobulin A from bronchopulmonary secretions blocks bactericidal and opsonizing effects of antibody to nontypable Haemophilus influenzae. Infect Immun (1984) 1.24

Immune complexes and humoral response to Pseudomonas aeruginosa in cystic fibrosis. Am Rev Respir Dis (1980) 1.22

Prediction and diagnosis of early Pseudomonas aeruginosa infection in cystic fibrosis: a follow-up study. J Clin Microbiol (1988) 1.20

Antibody to Pseudomonas aeruginosa mucoid exopolysaccharide and to sodium alginate in cystic fibrosis serum. Pediatr Res (1984) 1.09

Immunoglobulin A and immunoglobulin G antibody responses to alginates from Pseudomonas aeruginosa in patients with cystic fibrosis. J Clin Microbiol (1990) 1.08

Immune complexes and complement abnormalities in patients with cystic fibrosis. Increased mortality associated with circulating immune complexes and decreased function of the alternative complement pathway. Am Rev Respir Dis (1985) 0.93

Immunologic aspects of surface infections in the lung. J Pediatr (1986) 0.92

Mucoid Pseudomonas aeruginosa in cystic fibrosis. Aust Paediatr J (1982) 0.90

Loss of cryoprecipitability following proteolytic eleavage of the VH domains from a human IgG cryoglobulin. Mol Immunol (1980) 0.79

Articles by these authors

Computational modelling of visual attention. Nat Rev Neurosci (2001) 9.06

Invariant visual representation by single neurons in the human brain. Nature (2005) 6.41

The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs. J Neurosci (1993) 5.77

Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science (2000) 5.57

A saliency-based search mechanism for overt and covert shifts of visual attention. Vision Res (2000) 5.11

A direct quantitative relationship between the functional properties of human and macaque V5. Nat Neurosci (2000) 4.85

Shifts in selective visual attention: towards the underlying neural circuitry. Hum Neurobiol (1985) 4.78

Are we aware of neural activity in primary visual cortex? Nature (1995) 4.74

Atrial fibrillation following coronary artery bypass graft surgery: predictors, outcomes, and resource utilization. MultiCenter Study of Perioperative Ischemia Research Group. JAMA (1996) 4.50

Cellular factors couple recombination with growth phase: characterization of a new component in the lambda site-specific recombination pathway. Cell (1987) 3.94

Recurrent excitation in neocortical circuits. Science (1995) 3.38

Severity of cystic fibrosis in patients homozygous and heterozygous for delta F508 mutation. Lancet (1991) 3.37

Pathogenesis of cystic fibrosis. Lancet (1993) 3.34

Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment. Lancet (1991) 3.26

Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis. Pediatr Pulmonol (1997) 3.23

Category-specific visual responses of single neurons in the human medial temporal lobe. Nat Neurosci (2000) 3.21

Taxonomic dissection of the genus Micrococcus: Kocuria gen. nov., Nesterenkonia gen. nov., Kytococcus gen. nov., Dermacoccus gen. nov., and Micrococcus Cohn 1872 gen. emend. Int J Syst Bacteriol (1995) 3.16

Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus. Eur Respir J (2000) 3.14

Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta Paediatr Scand (1983) 3.13

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung. Microbiology (1999) 3.03

G inversion in bacteriophage Mu DNA is stimulated by a site within the invertase gene and a host factor. Cell (1985) 3.00

Computational vision and regularization theory. Nature (1985) 2.87

The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem (1994) 2.84

Full-length sequence and mosaic structure of a human immunodeficiency virus type 1 isolate from Thailand. J Virol (1996) 2.83

Purification and properties of the Escherichia coli host factor required for inversion of the G segment in bacteriophage Mu. J Biol Chem (1986) 2.75

Association between deficiency of mannose-binding lectin and severe infections after chemotherapy. Lancet (2001) 2.64

Improved survival in the Danish center-treated cystic fibrosis patients: results of aggressive treatment. Pediatr Pulmonol (1996) 2.55

N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms. Microbiology (2001) 2.51

Synaptic background activity influences spatiotemporal integration in single pyramidal cells. Proc Natl Acad Sci U S A (1991) 2.46

An epidemic spread of multiresistant Pseudomonas aeruginosa in a cystic fibrosis centre. J Antimicrob Chemother (1986) 2.43

Transient intestinal carriage after ingestion of antibiotic-resistant Enterococcus faecium from chicken and pork. N Engl J Med (2001) 2.38

Nonlinear interactions in a dendritic tree: localization, timing, and role in information processing. Proc Natl Acad Sci U S A (1983) 2.38

Recovery of virtually full-length HIV-1 provirus of diverse subtypes from primary virus cultures using the polymerase chain reaction. Virology (1995) 2.38

Comparison of discharge variability in vitro and in vivo in cat visual cortex neurons. J Neurophysiol (1996) 2.27

Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest (1999) 2.24

Constraints on cortical and thalamic projections: the no-strong-loops hypothesis. Nature (1998) 2.17

The elusive T cell receptor. Transplant Rev (1972) 2.14

Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm. Antimicrob Agents Chemother (1991) 2.09

From stimulus encoding to feature extraction in weakly electric fish. Nature (1996) 2.09

Rapid emergence of resistance in Pseudomonas aeruginosa in cystic fibrosis patients due to in-vivo selection of stable partially derepressed beta-lactamase producing strains. J Antimicrob Chemother (1990) 2.08

Retinal ganglion cells: a functional interpretation of dendritic morphology. Philos Trans R Soc Lond B Biol Sci (1982) 2.08

Occurrence of a common lipopolysaccharide antigen in standard and clinical strains of Pseudomonas aeruginosa. J Clin Microbiol (1989) 2.07

Attention activates winner-take-all competition among visual filters. Nat Neurosci (1999) 2.04

Respiratory infections in cystic fibrosis patients caused by virus, chlamydia and mycoplasma--possible synergism with Pseudomonas aeruginosa. Acta Paediatr Scand (1981) 2.03

Isolation of a fibronectin-binding protein from Staphylococcus aureus. Infect Immun (1982) 2.02

Three-dimensional structure of the E. coli DNA-binding protein FIS. Nature (1991) 2.01

Colistin inhalation therapy in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection. J Antimicrob Chemother (1987) 2.00

Consciousness and neuroscience. Cereb Cortex (1998) 1.99

Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice. J Antimicrob Chemother (2004) 1.96

Imagery neurons in the human brain. Nature (2000) 1.95

Localization of lung surfactant protein D on mucosal surfaces in human tissues. J Immunol (2000) 1.95

Candidate genes for the hypoxic tumor phenotype. Cancer Res (2000) 1.94

Cross-reactions between Legionella pneumophila (serogroup 1) and twenty-eight other bacterial species, including other members of the family Legionellaceae. Infect Immun (1983) 1.93

[Guidelines on antibiotics in the Laegeforeningens Medicinfortegnelse 2000]. Ugeskr Laeger (2001) 1.93

The E.coli fis promoter is subject to stringent control and autoregulation. EMBO J (1992) 1.92

Epidemiology of Pseudomonas aeruginosa infection in patients treated at a cystic fibrosis centre. Acta Pathol Microbiol Scand B (1980) 1.90

Crossed immunoelectrophoretic analysis of Legionella pneumophila serogroup 1 antigens. Infect Immun (1983) 1.89

Temporal precision of spike trains in extrastriate cortex of the behaving macaque monkey. Neural Comput (1996) 1.87

Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa. J Antimicrob Chemother (2000) 1.85

Results of multiple diagnostic tests for Mycobacterium avium subsp. paratuberculosis in patients with inflammatory bowel disease and in controls. J Clin Microbiol (2000) 1.85

Encoding of visual information by LGN bursts. J Neurophysiol (1999) 1.85

Shunting inhibition does not have a divisive effect on firing rates. Neural Comput (1997) 1.84

Eggs: conveniently packaged antibodies. Methods for purification of yolk IgG. J Immunol Methods (1981) 1.83

Infections with the unusual human pathogens Agrobacterium species and Ochrobactrum anthropi. Clin Infect Dis (1994) 1.83

Microbial load of drinking water reservoir tributaries during extreme rainfall and runoff. Appl Environ Microbiol (2002) 1.81

Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms. Infect Immun (1990) 1.81

Electrical interactions via the extracellular potential near cell bodies. J Comput Neurosci (1999) 1.81

Increasing frequency of vertebral osteomyelitis following Staphylococcus aureus bacteraemia in Denmark 1980-1990. J Infect (1997) 1.79

Sparse but not 'grandmother-cell' coding in the medial temporal lobe. Trends Cogn Sci (2008) 1.76

An antigen common to a wide range of bacteria. I. The isolation of a 'common antigen' from Pseudomonas aeruginosa. Acta Pathol Microbiol Scand B (1980) 1.75

Reconstitution of opsonizing activity by infusion of mannan-binding lectin (MBL) to MBL-deficient humans. Scand J Immunol (1998) 1.74

The control of retinogeniculate transmission in the mammalian lateral geniculate nucleus. Exp Brain Res (1986) 1.73

Lung infection with alginate-producing, mucoid Pseudomonas aeruginosa in cystic fibrosis. APMIS Suppl (1992) 1.71

Longitudinal study of immune response to Pseudomonas aeruginosa antigens in cystic fibrosis. Infect Immun (1983) 1.68

Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule. J Biol Chem (1997) 1.68

How voltage-dependent conductances can adapt to maximize the information encoded by neuronal firing rate. Nat Neurosci (1999) 1.68

The role of immune complexes in the pathogenesis of bacterial infections. Annu Rev Microbiol (1986) 1.67

Cystic fibrosis. 1. Pseudomonas aeruginosa infection in cystic fibrosis and its management. Thorax (1990) 1.67

Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa. Microbiology (2000) 1.66

Carriage of Staphylococcus aureus among 104 healthy persons during a 19-month period. Epidemiol Infect (1995) 1.63

Evolution and probable transmission of intersubtype recombinant human immunodeficiency virus type 1 in a Zambian couple. J Virol (1997) 1.62

Computational neuroscience. Science (1988) 1.61

Dicloxacillin and flucloxacillin: pharmacokinetics, protein binding and serum bactericidal titers in healthy subjects after oral administration. Infection (1995) 1.61

Increasing incidence but decreasing in-hospital mortality of adult Staphylococcus aureus bacteraemia between 1981 and 2000. Clin Microbiol Infect (2007) 1.61

Immunological cross-reaction between antigen Tp-4 of Treponema pallidum and an antigen common to a wide range of bacteria. Acta Pathol Microbiol Immunol Scand B (1984) 1.60

Increased antigen-specific Th-2 response in allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis. Pediatr Pulmonol (1999) 1.59

Proteases of Pseudomonas aeruginosa in patients with cystic fibrosis. J Infect Dis (1983) 1.56

Bone mineral status in 134 patients with cystic fibrosis. Arch Dis Child (1999) 1.55

Neural correlates of attention and working memory deficits in HIV patients. Neurology (2001) 1.55

Allergic bronchopulmonary aspergillosis in cystic fibrosis. A European epidemiological study. Epidemiologic Registry of Cystic Fibrosis. Eur Respir J (2000) 1.54

Are variable repeats in the spa gene suitable targets for epidemiological studies of methicillin-resistant Staphylococcus aureus strains? Eur J Clin Microbiol Infect Dis (1996) 1.54