Abhijit Guha

Author PubWeight™ 127.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The somatic genomic landscape of glioblastoma. Cell 2013 11.73
2 Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012 10.99
3 Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol 2008 7.30
4 Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 2005 5.21
5 Transforming fusions of FGFR and TACC genes in human glioblastoma. Science 2012 5.09
6 Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 2011 3.11
7 Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes Chromosomes Cancer 2004 3.05
8 Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme. J Exp Med 2011 2.93
9 Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma. AJNR Am J Neuroradiol 2005 1.90
10 Cancer stem cells are enriched in the side population cells in a mouse model of glioma. Cancer Res 2008 1.75
11 Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. FASEB J 2006 1.47
12 Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene 2002 1.45
13 High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. Cancer Res 2006 1.42
14 Targeting metabolic remodeling in glioblastoma multiforme. Oncotarget 2010 1.42
15 Peripheral nerve tumors: management strategies and molecular insights. J Neurooncol 2004 1.35
16 High-resolution DNA copy number profiling of malignant peripheral nerve sheath tumors using targeted microarray-based comparative genomic hybridization. Clin Cancer Res 2008 1.34
17 Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients. J Clin Invest 2011 1.27
18 Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors. Am J Pathol 2002 1.26
19 MicroRNA-10b regulates tumorigenesis in neurofibromatosis type 1. Cancer Sci 2010 1.23
20 Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model. Cancer Res 2003 1.20
21 Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor. Clin Cancer Res 2011 1.20
22 Extracellular vesicles--vehicles that spread cancer genes. Bioessays 2012 1.19
23 Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis. Cancer Res 2008 1.19
24 GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model. Proc Natl Acad Sci U S A 2007 1.15
25 Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model. Am J Pathol 2005 1.15
26 A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas. J Exp Med 2011 1.13
27 Multiinstitutional validation of the University of California at San Francisco Low-Grade Glioma Prognostic Scoring System. Clinical article. J Neurosurg 2009 1.12
28 Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractography. Neurosurgery 2011 1.10
29 Epidermal growth factor receptor variant III-induced glioma invasion is mediated through myristoylated alanine-rich protein kinase C substrate overexpression. Cancer Res 2009 1.10
30 Immune infiltration of spontaneous mouse astrocytomas is dominated by immunosuppressive cells from early stages of tumor development. Cancer Res 2010 1.07
31 Gene expression profiling reveals unique molecular subtypes of Neurofibromatosis Type I-associated and sporadic malignant peripheral nerve sheath tumors. Brain Pathol 2004 1.06
32 Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. J Proteome Res 2007 1.06
33 Orthopaedic manifestations of neurofibromatosis in children: an update. Clin Orthop Relat Res 2002 1.05
34 Glioblastoma multiforme after stereotactic radiotherapy for acoustic neuroma: case report and review of the literature. Neuro Oncol 2007 1.04
35 Suppression of glioblastoma tumorigenicity by the Kruppel-like transcription factor KLF6. Oncogene 2004 1.02
36 Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma. Genome Res 2012 1.02
37 The spectrum of somatic and germline NF1 mutations in NF1 patients with spinal neurofibromas. Neurogenetics 2009 1.02
38 A human transferrin-vascular endothelial growth factor (hnTf-VEGF) fusion protein containing an integrated binding site for (111)In for imaging tumor angiogenesis. J Nucl Med 2005 1.01
39 Targeting the Tie2/Tek receptor in astrocytomas. Am J Pathol 2004 1.01
40 A proximity ligation assay using transiently transfected, epitope-tagged proteins: application for in situ detection of dimerized receptor tyrosine kinases. Biotechniques 2010 1.00
41 Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme. Neurobiol Dis 2011 0.99
42 Molecular evolution of a neurofibroma to malignant peripheral nerve sheath tumor (MPNST) in an NF1 patient: correlation between histopathological, clinical and molecular findings. J Cancer Res Clin Oncol 2010 0.96
43 High-resolution longitudinal screening with magnetic resonance imaging in a murine brain cancer model. Neoplasia 2004 0.96
44 Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas. Neuro Oncol 2014 0.96
45 Mouse models to interrogate the implications of the differentiation status in the ontogeny of gliomas. Oncotarget 2011 0.95
46 Surgical management of cervical spine manifestations of neurofibromatosis Type 1: long-term clinical and radiological follow-up in 22 cases. J Neurosurg Spine 2011 0.94
47 Human schwannomas express activated platelet-derived growth factor receptors and c-kit and are growth inhibited by Gleevec (Imatinib Mesylate). Cancer Res 2009 0.94
48 Malignant peripheral nerve sheath tumors. Neurosurg Clin N Am 2004 0.94
49 Conditional astroglial Rictor overexpression induces malignant glioma in mice. PLoS One 2012 0.93
50 Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb. Mol Cell Proteomics 2012 0.91
51 Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (review). Int J Oncol 2003 0.90
52 In situ analysis of mutant EGFRs prevalent in glioblastoma multiforme reveals aberrant dimerization, activation, and differential response to anti-EGFR targeted therapy. Mol Cancer Res 2012 0.89
53 Potential role of 18fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating benign neurofibroma from malignant peripheral nerve sheath tumor associated with neurofibromatosis 1. Neurosurgery 2009 0.89
54 Loss of collapsin response mediator Protein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII. Cancer Res 2009 0.89
55 Genome-wide high-resolution analysis of DNA copy number alterations in NF1-associated malignant peripheral nerve sheath tumors using 32K BAC array. Genes Chromosomes Cancer 2009 0.88
56 Neoangiogenesis in human astrocytomas: expression and functional role of angiopoietins and their cognate receptors. Front Biosci 2003 0.88
57 Expression of GATA6 in the human and mouse central nervous system. Brain Res Dev Brain Res 2005 0.88
58 Malignant and benign ganglioglioma: a pathological and molecular study. Neuro Oncol 2007 0.87
59 Regulation of the pathological vasculature of malignant astrocytomas by angiopoietin-1. Neoplasia 2005 0.87
60 Role of Ang1 and its interaction with VEGF-A in astrocytomas. J Neuropathol Exp Neurol 2004 0.86
61 Preclinical in vivo evaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft. Int J Cancer 2010 0.86
62 Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis. Hum Mutat 2012 0.85
63 Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. Eur Spine J 2012 0.85
64 AIRP best cases in radiologic-pathologic correlation: Spinal conus dermoid cyst with lipid dissemination. Radiographics 2012 0.85
65 Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. Nucl Med Biol 2011 0.85
66 Angiogenesis in nervous system disorders. Neurosurgery 2003 0.85
67 Monoarticular pseudogout of the hip presenting as septic arthritis: a case report. Acta Orthop Traumatol Turc 2011 0.85
68 Information gaps for patients requiring craniotomy for benign brain lesion: a qualitative study. J Neurooncol 2009 0.85
69 Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells. Neuro Oncol 2002 0.85
70 Mouse glioma gene expression profiling identifies novel human glioma-associated genes. Ann Neurol 2002 0.85
71 Differential transformation capacity of neuro-glial progenitors during development. Proc Natl Acad Sci U S A 2013 0.85
72 Role of the Rap1 GTPase in astrocyte growth regulation. Glia 2003 0.84
73 A novel neurofibromin (NF1) interaction with the leucine-rich pentatricopeptide repeat motif-containing protein links neurofibromatosis type 1 and the French Canadian variant of Leigh's syndrome in a common molecular complex. J Neurosci Res 2013 0.84
74 Vestibular Schwannomas presenting with haemorrhage: clinical presentation and histopathological evaluation of an unusual entity. Br J Neurosurg 2009 0.83
75 Role of angiopoietin-2 in regulating growth and vascularity of astrocytomas. J Oncol 2010 0.83
76 Fractionated stereotactic radiotherapy for acoustic neuroma: single-institution experience at The Princess Margaret Hospital. Cancer 2007 0.82
77 Multiphoton ANS fluorescence microscopy as an in vivo sensor for protein misfolding stress. Cell Stress Chaperones 2011 0.81
78 Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Mol Cancer 2013 0.81
79 Aberrant G protein signaling in nervous system tumors. J Neurosurg 2002 0.81
80 Tumors of the central nervous system: clinical aspects, molecular mechanisms, unanswered questions, and future research directions. J Child Neurol 2008 0.81
81 Radiation induced peripheral nerve tumors: case series and review of the literature. J Neurooncol 2007 0.80
82 The need to protect the thyroid gland during image intensifier use in orthopaedic procedures. Acta Orthop Belg 2004 0.80
83 Intermittent atlantoaxial subluxation caused by a prolapsing neurofibroma. Case report. J Neurosurg Spine 2008 0.79
84 Intracranial halo pin penetration causing brain injury secondary to poor halo care technique: a case report and literature review. Cases J 2008 0.79
85 Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals. Genes Chromosomes Cancer 2008 0.79
86 Proteomics: present and future implications in neuro-oncology. Neurosurgery 2008 0.79
87 Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging. Glia 2007 0.78
88 Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression. Int J Oncol 2003 0.78
89 Loss of p53 cooperates with K-ras activation to induce glioma formation in a region-independent manner. Glia 2013 0.78
90 Investigation of the in vitro therapeutic efficacy of nilotinib in immortalized human NF2-null vestibular schwannoma cells. PLoS One 2012 0.77
91 Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes. FEBS Lett 2013 0.77
92 Peripheral nerve tumors. Handb Clin Neurol 2012 0.76
93 Characterization and transformation potential of "Synthetic" astrocytes differentiated from murine embryonic stem cells. Glia 2008 0.75
94 Lipoma compressing the brachial plexus in a patient with sarcoidosis: case report. Br J Neurosurg 2011 0.75
95 Glioblastoma multiforme occurring in a patient treated with gamma knife surgery: case report and review of the literature. J Neurosurg 2013 0.75
96 Clinical and radiographic evaluation of the cavus foot: surgical implications. Foot Ankle Clin 2013 0.75
97 The role of ankle arthroscopy in acute ankle injuries of the athlete. Foot Ankle Clin 2013 0.75
98 Metaplastic bone formation in a low grade conus glioma: case report and review of the literature. J Neurooncol 2003 0.75
99 896 Anatomic Variants of Ependymoma Arise from Distinct Subsets of Radial Glial Cells. Neurosurgery 2005 0.75
100 Comparison of three different fixation methods of calcaneal osteotomies. Foot Ankle Int 2013 0.75