Published in Biochemistry on October 05, 2004
The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J Biol Chem (2009) 1.38
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. J Biol Chem (2008) 1.37
Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proc Natl Acad Sci U S A (2008) 1.29
Cooperative properties of cytochromes P450. Pharmacol Ther (2009) 1.09
CYP153A6, a soluble P450 oxygenase catalyzing terminal-alkane hydroxylation. J Bacteriol (2006) 1.07
Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formation. J Am Chem Soc (2008) 0.99
Spectroscopic features of cytochrome P450 reaction intermediates. Arch Biochem Biophys (2010) 0.98
Unusual spectroscopic and ligand binding properties of the cytochrome P450-flavodoxin fusion enzyme XplA. J Biol Chem (2012) 0.84
A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid. Biochemistry (2011) 0.84
Development of biotin-prototrophic and -hyperauxotrophic Corynebacterium glutamicum strains. Appl Environ Microbiol (2013) 0.80
Cj1411c encodes for a cytochrome P450 involved in Campylobacter jejuni 81-176 pathogenicity. PLoS One (2013) 0.77
Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J Biol Chem (2016) 0.75
Spectroscopic studies of the cytochrome P450 reaction mechanisms. Biochim Biophys Acta (2017) 0.75
The origins of 168, W23, and other Bacillus subtilis legacy strains. J Bacteriol (2008) 2.86
Atomic description of an enzyme reaction dominated by proton tunneling. Science (2006) 2.84
The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase. Nature (2011) 2.32
Global goals for oral health 2020. Int Dent J (2003) 2.00
Control of enhanced Raman scattering using a DNA-based assembly process of dye-coded nanoparticles. Nat Nanotechnol (2008) 1.79
Nitrate transport and signalling. J Exp Bot (2007) 1.77
H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein. J Mol Biol (2002) 1.70
Evaluation of surface-enhanced resonance Raman scattering for quantitative DNA analysis. Anal Chem (2004) 1.65
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed. Insect Biochem Mol Biol (2011) 1.59
Buprenorphine and methadone: a comparison of patient completion rates during inpatient detoxification. J Addict Dis (2007) 1.59
Characterization of a two-component high-affinity nitrate uptake system in Arabidopsis. Physiology and protein-protein interaction. Plant Physiol (2006) 1.55
Extended megadroughts in the southwestern United States during Pleistocene interglacials. Nature (2011) 1.55
Extracellular Ca2+ ameliorates NaCl-induced K+ loss from Arabidopsis root and leaf cells by controlling plasma membrane K+ -permeable channels. Plant Physiol (2006) 1.54
Small untranslated RNA antitoxin in Bacillus subtilis. J Bacteriol (2005) 1.49
Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster. J Biol Chem (2004) 1.42
Genes for small, noncoding RNAs under sporulation control in Bacillus subtilis. J Bacteriol (2006) 1.41
Biochemical and structural insights into bacterial organelle form and biogenesis. J Biol Chem (2008) 1.41
Reengineering orthogonally selective riboswitches. Proc Natl Acad Sci U S A (2010) 1.41
Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes. Microbiology (2002) 1.40
Dynamics driving function: new insights from electron transferring flavoproteins and partner complexes. FEBS J (2007) 1.38
The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J Biol Chem (2009) 1.38
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. J Biol Chem (2008) 1.37
The effect of core destabilization on the mechanical resistance of I27. Biophys J (2002) 1.36
Surface-enhanced Raman scattering (SERS) and surface-enhanced resonance Raman scattering (SERRS): a review of applications. Appl Spectrosc (2011) 1.31
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450. J Biol Chem (2002) 1.31
Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases. Philos Trans R Soc Lond B Biol Sci (2013) 1.30
Arabidopsis root K+-efflux conductance activated by hydroxyl radicals: single-channel properties, genetic basis and involvement in stress-induced cell death. J Cell Sci (2010) 1.29
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies. Cancer Res (2005) 1.29
The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord (2002) 1.28
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR. Proc Natl Acad Sci U S A (2007) 1.27
Unusual cytochrome p450 enzymes and reactions. J Biol Chem (2013) 1.24
Bacterial flavodoxins support nitric oxide production by Bacillus subtilis nitric-oxide synthase. J Biol Chem (2006) 1.22
Supramolecular motifs in s-block metal-bound sulfonated monoazo dyes, part 1: structural class controlled by cation type and modulated by sulfonate aryl ring position. Chemistry (2004) 1.22
Electron energy-loss spectroscopy (EELS) of surface plasmons in single silver nanoparticles and dimers: influence of beam damage and mapping of dark modes. ACS Nano (2009) 1.21
Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. J Biol Chem (2006) 1.21
Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors. J Biol Chem (2008) 1.20
Roles of divalent metal ions in flap endonuclease-substrate interactions. Nat Struct Mol Biol (2004) 1.19
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme. EMBO J (2002) 1.19
Extensive conformational sampling in a ternary electron transfer complex. Nat Struct Biol (2003) 1.17
Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction. J Am Chem Soc (2009) 1.17
The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex. FEBS J (2008) 1.17
Amino acids and nitrate as signals for the regulation of nitrogen acquisition. J Exp Bot (2007) 1.16
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen. J Biol Chem (2010) 1.16
Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions. J Am Chem Soc (2010) 1.16
Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator. Mol Microbiol (2008) 1.16
Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects. Proc Natl Acad Sci U S A (2007) 1.16
Instantaneous, stoichiometric generation of powerfully reducing states of protein active sites using Eu(II) and polyaminocarboxylate ligands. Chem Commun (Camb) (2003) 1.16
Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J Biol Chem (2009) 1.15
SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. Analyst (2004) 1.15
The O2 sensitivity of the transcription factor FNR is controlled by Ser24 modulating the kinetics of [4Fe-4S] to [2Fe-2S] conversion. Proc Natl Acad Sci U S A (2009) 1.15
Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems. Philos Trans R Soc Lond B Biol Sci (2006) 1.15
Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis. J Inorg Biochem (2002) 1.15
Redox and spectroscopic properties of human indoleamine 2,3-dioxygenase and a His303Ala variant: implications for catalysis. Biochemistry (2005) 1.13
Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase. Chembiochem (2013) 1.12
Ultrasensitive DNA detection using oligonucleotide-silver nanoparticle conjugates. Anal Chem (2008) 1.11
Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase. J Am Chem Soc (2008) 1.11
The preponderance of P450s in the Mycobacterium tuberculosis genome. Trends Microbiol (2006) 1.11
Extensive domain motion and electron transfer in the human electron transferring flavoprotein.medium chain Acyl-CoA dehydrogenase complex. J Biol Chem (2004) 1.10
Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations. Biochemistry (2008) 1.10
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2. J Leukoc Biol (2004) 1.09
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase. Biochemistry (2008) 1.09
Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1). J Med Chem (2009) 1.09
Drug block of the hERG potassium channel: insight from modeling. Proteins (2007) 1.09
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions. Biochemistry (2006) 1.08
A functional description of CymA, an electron-transfer hub supporting anaerobic respiratory flexibility in Shewanella. Biochem J (2012) 1.08
Alpha-secondary isotope effects as probes of "tunneling-ready" configurations in enzymatic H-tunneling: insight from environmentally coupled tunneling models. J Am Chem Soc (2006) 1.08
Conformational and thermodynamic control of electron transfer in neuronal nitric oxide synthase. Biochemistry (2007) 1.07
Identification and characterization of a novel vitamin B12 (cobalamin) biosynthetic enzyme (CobZ) from Rhodobacter capsulatus, containing flavin, heme, and Fe-S cofactors. J Biol Chem (2004) 1.07
SERRS. In situ substrate formation and improved detection using microfluidics. Anal Chem (2002) 1.06
Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. Biochemistry (2004) 1.06
Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase. Nat Commun (2012) 1.06
Simple multiplex genotyping by surface-enhanced resonance Raman scattering. Anal Chem (2002) 1.05
Enhanced oligonucleotide-nanoparticle conjugate stability using thioctic acid modified oligonucleotides. Nucleic Acids Res (2007) 1.04
Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3. J Biol Chem (2006) 1.04
Advances in the analysis of isothermal titration calorimetry data for ligand-DNA interactions. Methods (2007) 1.04
Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems. Arch Biochem Biophys (2007) 1.04
Comparing nitrate storage and remobilization in two rice cultivars that differ in their nitrogen use efficiency. J Exp Bot (2007) 1.04
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium. Biochemistry (2004) 1.03
Influence of the environment on the [4Fe-4S]2+ to [2Fe-2S]2+ cluster switch in the transcriptional regulator FNR. J Am Chem Soc (2008) 1.03
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs. Mol Pharmacol (2005) 1.03