Toll-like receptors in the pathogenesis of human disease.

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol (2009) 5.05

Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nat Rev Immunol (2006) 4.05

Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. Genes Dev (2006) 3.68

Function of Nod-like receptors in microbial recognition and host defense. Immunol Rev (2009) 3.20

Reconstructing immune phylogeny: new perspectives. Nat Rev Immunol (2005) 2.95

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell (2010) 2.89

The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis. J Immunol (2006) 2.83

Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol (2010) 2.63

Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol (2008) 2.44

Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci U S A (2005) 1.95

TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J Leukoc Biol (2009) 1.87

Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections. Cell Host Microbe (2011) 1.86

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis. J Infect Dis (2006) 1.83

Etiopathogenesis of inflammatory bowel diseases. World J Gastroenterol (2006) 1.79

Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol (2007) 1.78

Sleep loss activates cellular markers of inflammation: sex differences. Brain Behav Immun (2009) 1.68

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia. Blood (2015) 1.66

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell (2009) 1.64

Identification and characterization of a loss-of-function human MPYS variant. Genes Immun (2011) 1.60

Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs. Semin Immunopathol (2007) 1.54

FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells. Blood (2005) 1.54

Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages. Proc Natl Acad Sci U S A (2005) 1.40

Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci U S A (2005) 1.39

Eating ourselves to death (and despair): the contribution of adiposity and inflammation to depression. Prog Neurobiol (2010) 1.38

Sleep depth and fatigue: role of cellular inflammatory activation. Brain Behav Immun (2010) 1.31

T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production. Proc Natl Acad Sci U S A (2007) 1.29

Antagonism of airway tolerance by endotoxin/lipopolysaccharide through promoting OX40L and suppressing antigen-specific Foxp3+ T regulatory cells. J Immunol (2008) 1.27

Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann Rheum Dis (2007) 1.26

MicroRNAs in inflammatory lung disease--master regulators or target practice? Respir Res (2010) 1.24

Exploitation of the Toll-like receptor system in cancer: a doubled-edged sword? Br J Cancer (2006) 1.23

Mammalian Toll-like receptors: to immunity and beyond. Clin Exp Immunol (2005) 1.23

Identification of novel genes that mediate innate immunity using inbred mice. Genetics (2009) 1.22

Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling. J Biol Chem (2006) 1.21

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. Respir Res (2006) 1.20

Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily. Sci Signal (2012) 1.20

Inflammatory and immune pathways in the pathogenesis of periodontal disease. Periodontol 2000 (2014) 1.20

Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature. Proc Natl Acad Sci U S A (2009) 1.20

The human TLR innate immune gene family is differentially influenced by DNA stress and p53 status in cancer cells. Cancer Res (2012) 1.19

Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. J Immunol (2012) 1.16

Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo. J Neuroinflammation (2004) 1.15

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol 2000 (2010) 1.15

Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties. J Biol Chem (2011) 1.14

Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math Biosci (2008) 1.13

TRIM38 negatively regulates TLR3-mediated IFN-β signaling by targeting TRIF for degradation. PLoS One (2012) 1.11

Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci U S A (2008) 1.10

Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes. PLoS One (2010) 1.08

Mast cell function: a new vision of an old cell. J Histochem Cytochem (2014) 1.08

Alternate transcription of the Toll-like receptor signaling cascade. Genome Biol (2006) 1.08

Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes. Clin Exp Immunol (2008) 1.07

Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans. Pediatr Res (2009) 1.07

Oral inflammatory diseases and systemic inflammation: role of the macrophage. Front Immunol (2012) 1.07

The role of microRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation. Innate Immun (2012) 1.07

Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors. BMC Cancer (2013) 1.06

Variants in the Toll-interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population. Crit Care (2011) 1.05

Emergent genome-wide control in wildtype and genetically mutated lipopolysaccarides-stimulated macrophages. PLoS One (2009) 1.04

Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling. Nat Commun (2011) 1.04

Novel regulators of the systemic response to lipopolysaccharide. Am J Respir Cell Mol Biol (2010) 1.04

Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. Circulation (2010) 1.04

The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis. J Immunol (2011) 1.02

The application of Toll like receptors for cancer therapy. Int J Biol Sci (2010) 1.01

Inflammatory role of Toll-like receptors in human and murine adipose tissue. Mediators Inflamm (2010) 1.01

Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications. J Immunol Res (2015) 1.00

Suppression of LPS-induced inflammatory responses in macrophages infected with Leishmania. J Inflamm (Lond) (2010) 1.00

The multiple facets of toll-like receptors in transplantation biology. Transplantation (2008) 0.99

Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial. Biol Psychiatry (2015) 0.99

Toll-like receptors in skin infections and inflammatory diseases. Infect Disord Drug Targets (2008) 0.99

Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 0.98

Single-stranded oligonucleotides can inhibit cytokine production induced by human toll-like receptor 3. Mol Cell Biol (2008) 0.97

Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. Genetics (2013) 0.97

Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability. Clin Chem (2008) 0.97

Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease. Respir Res (2006) 0.97

Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases. Immunology (2007) 0.96

Cellular and Molecular Connections between Autophagy and Inflammation. Mediators Inflamm (2015) 0.96

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases. BMC Immunol (2014) 0.95

Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression. J Biol Chem (2013) 0.94

Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages. J Immunol (2008) 0.94

Protective immunity against hepatitis C: many shades of gray. Front Immunol (2014) 0.94

Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans. J Immunol (2011) 0.93

Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. BMC Med Genet (2005) 0.93

Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1. Structure (2008) 0.93

Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas. Immunology (2008) 0.92

The antimicrobial peptide HBD-2 and the Toll-like receptors-2 and -4 are induced in synovial membranes in case of septic arthritis. Virchows Arch (2009) 0.92

Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. PLoS Pathog (2013) 0.92

Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils. Respir Res (2010) 0.92

Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1. J Biol Chem (2010) 0.92

Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of Cameroon. PLoS One (2013) 0.91

Lectin receptor kinases in plant innate immunity. Front Plant Sci (2013) 0.91

Isolated Toll-like receptor transmembrane domains are capable of oligomerization. PLoS One (2012) 0.91

MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages. BMC Chem Biol (2010) 0.90

Mycobacteria-induced suppression of autoimmunity in the central nervous system. J Neuroimmune Pharmacol (2010) 0.90

Bacterial DNA induces pulmonary damage via TLR-9 through cross-talk with neutrophils. Shock (2011) 0.90

TLR-2 Arg753Gln, TLR-4 Asp299Gly, and TLR-4 Thr399Ile polymorphisms in Henoch Schonlein purpura with and without renal involvement. Rheumatol Int (2009) 0.89

A single nucleotide polymorphism in 3'-untranslated region contributes to the regulation of Toll-like receptor 4 translation. J Biol Chem (2012) 0.89

The regulatory toll-like receptor 4 genetic polymorphism rs11536889 is associated with renal, coagulation and hepatic organ failure in sepsis patients. J Transl Med (2014) 0.89

Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer. Infect Agent Cancer (2012) 0.89

Burn-induced alterations in toll-like receptor-mediated responses by bronchoalveolar lavage cells. Cytokine (2011) 0.89

Oxalate toxicity in renal cells. Urol Res (2005) 0.88

Human experimental endotoxemia in modeling the pathophysiology, genomics, and therapeutics of innate immunity in complex cardiometabolic diseases. Arterioscler Thromb Vasc Biol (2014) 0.88

Expression and function of dectin-1 is defective in monocytes from patients with systemic lupus erythematosus and rheumatoid arthritis. J Clin Immunol (2012) 0.88

No indication for a defect in toll-like receptor signaling in patients with hyper-IgE syndrome. J Clin Immunol (2005) 0.87

A common MUC5B promoter polymorphism and pulmonary fibrosis. N Engl J Med (2011) 6.40

Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23

A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med (2004) 6.02

Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med (2002) 6.00

Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron (2005) 4.78

Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. Am J Respir Crit Care Med (2002) 4.66

Clinical and pathologic features of familial interstitial pneumonia. Am J Respir Crit Care Med (2005) 4.25

The clinical course of patients with idiopathic pulmonary fibrosis. Ann Intern Med (2005) 4.25

Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med (2002) 4.00

Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum (2003) 3.73

In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest (2008) 3.35

Gene expression profiling of familial and sporadic interstitial pneumonia. Am J Respir Crit Care Med (2006) 3.32

Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25

Protection from experimental asthma by an endogenous bronchodilator. Science (2005) 3.17

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet (2013) 3.17

The extracellular release of HMGB1 during apoptotic cell death. Am J Physiol Cell Physiol (2006) 2.90

HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol (2012) 2.75

Allergen-induced airway disease is mouse strain dependent. Am J Physiol Lung Cell Mol Physiol (2003) 2.56

The role of innate immunity in acute allograft rejection after lung transplantation. Am J Respir Crit Care Med (2003) 2.44

The role of Toll-like receptor 4 in environmental airway injury in mice. Am J Respir Crit Care Med (2004) 2.43

DNA microarrays: boundless technology or bound by technology? Guidelines for studies using microarray technology. Arthritis Rheum (2002) 2.35

MUC5B promoter polymorphism and interstitial lung abnormalities. N Engl J Med (2013) 2.31

Exposures to the Kuwait oil fires and their association with asthma and bronchitis among gulf war veterans. Environ Health Perspect (2002) 2.24

Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis. JAMA (2013) 2.20

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2014) 2.17

Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. Chest (2003) 2.16

Concern TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med (2009) 2.07

The pathophysiology of asthma. Annu Rev Med (2002) 1.98

The acute respiratory distress syndrome. Ann Intern Med (2004) 1.96

High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis. Am J Respir Crit Care Med (2005) 1.90

The role of biomechanics and inflammation in cartilage injury and repair. Clin Orthop Relat Res (2004) 1.89

Informed consent in a clinical trial of a novel treatment for rheumatoid arthritis. Arthritis Rheum (2003) 1.86

Beta-arrestin-2 regulates the development of allergic asthma. J Clin Invest (2003) 1.85

Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol (2007) 1.78

The role of microparticles in the pathogenesis of rheumatic diseases. Nat Rev Rheumatol (2009) 1.78

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium. PLoS One (2013) 1.78

Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax (2013) 1.77

Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2002) 1.76

Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. FASEB J (2005) 1.72

The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. Proc Natl Acad Sci U S A (2005) 1.71

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. J Virol (2008) 1.69

Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol (2012) 1.67

Routine vs. selective EUS-guided FNA approach for preoperative nodal staging of esophageal carcinoma. Gastrointest Endosc (2006) 1.67

Associations, populations, and the truth: recommendations for genetic association studies in Arthritis & Rheumatism. Arthritis Rheum (2004) 1.66

Microparticles as regulators of inflammation: novel players of cellular crosstalk in the rheumatic diseases. Arthritis Rheum (2005) 1.64

Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2014) 1.63

Analyses of efficacy end points in a controlled trial of interferon-gamma1b for idiopathic pulmonary fibrosis. Chest (2005) 1.60

Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis. Cancer Biol Ther (2002) 1.58

Gulf War veterans with anxiety: prevalence, comorbidity, and risk factors. Epidemiology (2004) 1.57

Molecular phenotypes distinguish patients with relatively stable from progressive idiopathic pulmonary fibrosis (IPF). PLoS One (2009) 1.56

Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem (2009) 1.55

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Am J Respir Crit Care Med (2014) 1.54

Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis. Am J Respir Cell Mol Biol (2008) 1.51

Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values. Bioinformatics (2012) 1.49

The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation. Am J Respir Crit Care Med (2004) 1.48

The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. J Immunol (2007) 1.46

Retracted Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice. Am J Respir Cell Mol Biol (2010) 1.44

Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest (2009) 1.41

Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population. Pediatr Res (2002) 1.39

Microparticles as mediators of cellular cross-talk in inflammatory disease. Autoimmunity (2006) 1.38

TLR4 signaling attenuates ongoing allergic inflammation. J Immunol (2006) 1.38

Posttraumatic stress disorder and self-reported physical health status among U.S. Military personnel serving during the Gulf War period: a population-based study. Psychosomatics (2002) 1.33

Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol (2006) 1.32

Innate immunity influences long-term outcomes after human lung transplant. Am J Respir Crit Care Med (2005) 1.31

The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells. Immunology (2005) 1.28

Plasminogen alleles influence susceptibility to invasive aspergillosis. PLoS Genet (2008) 1.25

The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis. Exp Cell Res (2008) 1.24

Epigenetic control of gene expression in the lung. Am J Respir Crit Care Med (2011) 1.24

Neutrophils play a critical role in development of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol (2002) 1.23

Developments in the scientific understanding of lupus. Arthritis Res Ther (2008) 1.22

Identification of novel genes that mediate innate immunity using inbred mice. Genetics (2009) 1.22

The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population. PLoS One (2013) 1.21

Ambient ozone primes pulmonary innate immunity in mice. J Immunol (2007) 1.21

Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide. Infect Immun (2002) 1.21

Small bowel adenocarcinoma complicating Crohn's disease: case series and review of the literature. Am Surg (2007) 1.21

Regulation of matrix turnover in meniscal explants: role of mechanical stress, interleukin-1, and nitric oxide. J Appl Physiol (1985) (2003) 1.20

The role of IFN-alpha and nitric oxide in the release of HMGB1 by RAW 264.7 cells stimulated with polyinosinic-polycytidylic acid or lipopolysaccharide. J Immunol (2006) 1.20

Susceptibility to asbestos-induced and transforming growth factor-beta1-induced fibroproliferative lung disease in two strains of mice. Am J Respir Cell Mol Biol (2002) 1.19

Role of macrophages in the generation of circulating blood nucleosomes from dead and dying cells. Blood (2003) 1.19

Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. J Autoimmun (2011) 1.18

Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. Arthritis Rheum (2007) 1.17

Complement levels and activity in the normal and LPS-injured lung. Am J Physiol Lung Cell Mol Physiol (2006) 1.15

Rare variants in RTEL1 are associated with familial interstitial pneumonia. Am J Respir Crit Care Med (2015) 1.15

Emerging treatments for complex perianal fistula in Crohn's disease. World J Gastroenterol (2009) 1.15

Ozone-induced acute pulmonary injury in inbred mouse strains. Am J Respir Cell Mol Biol (2004) 1.14

Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury. J Immunol (2007) 1.14

Genetic basis of murine responses to hyperoxia-induced lung injury. Immunogenetics (2006) 1.13

Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. Am J Respir Cell Mol Biol (2009) 1.12

CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol (2007) 1.11

Public health importance of Brachiola algerae (Microsporidia)--an emerging pathogen of humans. Folia Parasitol (Praha) (2005) 1.11

Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol (2011) 1.11

Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci U S A (2008) 1.10

The pulmonary fibrosis-associated MUC5B promoter polymorphism does not influence the development of interstitial pneumonia in systemic sclerosis. Chest (2012) 1.10

CD11b and intercellular adhesion molecule-1 are involved in pulmonary neutrophil recruitment in lipopolysaccharide-induced airway disease. Am J Respir Cell Mol Biol (2002) 1.09

Molecular mechanisms in progressive idiopathic pulmonary fibrosis. Annu Rev Med (2012) 1.09

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts. Crit Care (2010) 1.08

The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis. Arthritis Rheum (2008) 1.08

The peripheral blood transcriptome identifies the presence and extent of disease in idiopathic pulmonary fibrosis. PLoS One (2012) 1.07

Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. Transplantation (2007) 1.07

Survey of gastroenterologists' awareness and implementation of AGA guidelines on osteoporosis in inflammatory bowel disease patients: are the guidelines being used and what are the barriers to their use? Inflamm Bowel Dis (2009) 1.07