Published in Nature on September 30, 2004
Guidelines on nicotine dose selection for in vivo research. Psychopharmacology (Berl) (2006) 3.68
A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron (2009) 2.07
Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans. Genes Dev (2007) 1.94
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol (2009) 1.85
Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. EMBO J (2005) 1.73
A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics (2005) 1.72
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor. Proc Natl Acad Sci U S A (2008) 1.64
The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans. Genetica (2009) 1.42
A secreted complement-control-related protein ensures acetylcholine receptor clustering. Nature (2009) 1.33
Synaptic targeting and functional modulation of GluK1 kainate receptors by the auxiliary neuropilin and tolloid-like (NETO) proteins. J Neurosci (2011) 1.30
Neto1 is an auxiliary subunit of native synaptic kainate receptors. J Neurosci (2011) 1.26
Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50. EMBO J (2007) 1.24
Characterization of Mos1-mediated mutagenesis in Caenorhabditis elegans: a method for the rapid identification of mutated genes. Genetics (2005) 1.24
WNTs tune up the neuromuscular junction. Nat Rev Neurosci (2009) 1.17
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol (2009) 1.16
Levamisole resistance resolved at the single-channel level in Caenorhabditis elegans. FASEB J (2008) 1.16
SOL-1 is an auxiliary subunit that modulates the gating of GLR-1 glutamate receptors in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2006) 1.09
Dancing partners at the synapse: auxiliary subunits that shape kainate receptor function. Nat Rev Neurosci (2012) 1.09
Biomechanical profiling of Caenorhabditis elegans motility. Genetics (2012) 1.08
The Dunce cAMP phosphodiesterase PDE-4 negatively regulates G alpha(s)-dependent and G alpha(s)-independent cAMP pools in the Caenorhabditis elegans synaptic signaling network. Genetics (2006) 1.07
Wnt signaling in neuromuscular junction development. Cold Spring Harb Perspect Biol (2012) 1.05
Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction. Genes Dev (2012) 1.00
An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse. EMBO J (2009) 1.00
Regulation of ionotropic glutamate receptors by their auxiliary subunits. Physiology (Bethesda) (2010) 0.97
Levamisole receptors: a second awakening. Trends Parasitol (2012) 0.96
A single immunoglobulin-domain protein required for clustering acetylcholine receptors in C. elegans. EMBO J (2011) 0.94
The SOL-2/Neto auxiliary protein modulates the function of AMPA-subtype ionotropic glutamate receptors. Neuron (2012) 0.92
The immunoglobulin super family protein RIG-3 prevents synaptic potentiation and regulates Wnt signaling. Neuron (2011) 0.90
The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. J Biol Chem (2008) 0.90
C. elegans agrin is expressed in pharynx, IL1 neurons and distal tip cells and does not genetically interact with genes involved in synaptogenesis or muscle function. PLoS One (2007) 0.87
C. elegans Punctin specifies cholinergic versus GABAergic identity of postsynaptic domains. Nature (2014) 0.87
Na+/K+ ATPase regulates the expression and localization of acetylcholine receptors in a pump activity-independent manner. Mol Cell Neurosci (2008) 0.86
Acetylcholine receptors enable the transport of rapsyn from the Golgi complex to the plasma membrane. J Neurosci (2012) 0.85
Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit. Nat Neurosci (2012) 0.85
Development of a database system for mapping insertional mutations onto the mouse genome with large-scale experimental data. BMC Genomics (2009) 0.82
Single-channel recording from adult Brugia malayi. Invert Neurosci (2011) 0.82
Levamisole and ryanodine receptors. I: A contraction study in Ascaris suum. Mol Biochem Parasitol (2010) 0.81
Manipulating the Caenorhabditis elegans genome using mariner transposons. Genetica (2009) 0.81
Advances in synapse formation: forging connections in the worm. Wiley Interdiscip Rev Dev Biol (2014) 0.80
Control of rapsyn stability by the CUL-3-containing E3 ligase complex. J Biol Chem (2009) 0.80
GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron (2017) 0.79
From genes to function: the C. elegans genetic toolbox. Wiley Interdiscip Rev Dev Biol (2011) 0.79
Proteolytic processing of the extracellular scaffolding protein LEV-9 is required for clustering acetylcholine receptors. J Biol Chem (2014) 0.76
Meeting report: 2010 Caenorhabditis elegans Neurobiology Meeting, University of Wisconsin, USA. Invert Neurosci (2010) 0.75
FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice. Biol Open (2013) 0.75
AMPA receptor trafficking at excitatory synapses. Neuron (2003) 7.11
EphB receptors interact with NMDA receptors and regulate excitatory synapse formation. Cell (2000) 4.34
Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans. Genetics (1993) 4.18
The genetics of levamisole resistance in the nematode Caenorhabditis elegans. Genetics (1980) 3.98
One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nat Neurosci (1999) 3.88
Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product Narp. Neuron (1999) 3.28
Megalin and cubilin: multifunctional endocytic receptors. Nat Rev Mol Cell Biol (2002) 3.13
Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans. Genetics (1995) 3.11
The CUB domain. A widespread module in developmentally regulated proteins. J Mol Biol (1993) 3.08
Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2. Nature (2003) 3.01
The role of receptor diffusion in the organization of the postsynaptic membrane. Nat Rev Neurosci (2003) 2.78
A new marker for mosaic analysis in Caenorhabditis elegans indicates a fusion between hyp6 and hyp7, two major components of the hypodermis. Genetics (1998) 2.67
Lipoprotein receptors in the nervous system. Annu Rev Biochem (2001) 2.61
Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line. Nature (2001) 2.55
Levamisole-resistant mutants of the nematode Caenorhabditis elegans appear to lack pharmacological acetylcholine receptors. Neuroscience (1980) 2.44
Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits. J Neurosci (1997) 2.31
The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter. Science (1993) 2.26
The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J Neurosci (1999) 2.03
Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses. Science (2004) 1.97
SOL-1 is a CUB-domain protein required for GLR-1 glutamate receptor function in C. elegans. Nature (2004) 1.89
eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx. Genetics (2004) 1.65
RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous system. Neuron (2000) 1.57
Cholinergic receptor mutants of the nematode Caenorhabditis elegans. J Neurosci (1987) 1.56
GABA is dispensable for the formation of junctional GABA receptor clusters in Caenorhabditis elegans. J Neurosci (2003) 1.25
Acetylcholine receptors direct rapsyn clusters to the neuromuscular synapse in zebrafish. J Neurosci (2004) 1.24
Identified neurons in C. elegans coexpress vesicular transporters for acetylcholine and monoamines. Am J Physiol Cell Physiol (2001) 1.11
A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in restricted areas of mouse brain. Biochem Biophys Res Commun (2003) 0.97
Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron (2003) 5.38
Targeted engineering of the Caenorhabditis elegans genome following Mos1-triggered chromosomal breaks. EMBO J (2006) 2.62
Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. PLoS Biol (2006) 2.55
Maturation of active zone assembly by Drosophila Bruchpilot. J Cell Biol (2009) 2.34
TFG-1 function in protein secretion and oncogenesis. Nat Cell Biol (2011) 2.13
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J (2010) 2.12
Defects in synaptic vesicle docking in unc-18 mutants. Nat Neurosci (2003) 2.11
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction. J Biol Chem (2005) 1.87
The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit. J Biol Chem (2004) 1.70
UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains. J Neurosci (2006) 1.65
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor. Proc Natl Acad Sci U S A (2008) 1.64
Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition. Mol Biol Cell (2008) 1.61
Preservation of immunoreactivity and fine structure of adult C. elegans tissues using high-pressure freezing. J Histochem Cytochem (2004) 1.52
Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM. J Biol Chem (2006) 1.42
Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans. J Neurosci (2005) 1.40
Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth. J Biol Chem (2009) 1.36
Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans. J Neurosci (2006) 1.35
A secreted complement-control-related protein ensures acetylcholine receptor clustering. Nature (2009) 1.33
The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor alpha subunit. J Neurochem (2005) 1.31
The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces. J Cell Biol (2003) 1.30
A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. PLoS Biol (2009) 1.27
GABA is dispensable for the formation of junctional GABA receptor clusters in Caenorhabditis elegans. J Neurosci (2003) 1.25
Mos1-mediated insertional mutagenesis in Caenorhabditis elegans. Nat Protoc (2007) 1.24
Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50. EMBO J (2007) 1.24
Characterization of Mos1-mediated mutagenesis in Caenorhabditis elegans: a method for the rapid identification of mutated genes. Genetics (2005) 1.24
The endoplasmic reticulum localized PIN8 is a pollen-specific auxin carrier involved in intracellular auxin homeostasis. Plant J (2012) 1.20
The C. elegans P4-ATPase TAT-1 regulates lysosome biogenesis and endocytosis. Traffic (2008) 1.19
Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density. Neurosci Lett (2008) 1.18
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol (2009) 1.16
The GxGD motif of presenilin contributes to catalytic function and substrate identification of gamma-secretase. J Neurosci (2006) 1.13
Activation of nicotinic receptors uncouples a developmental timer from the molting timer in C. elegans. Development (2006) 1.12
Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapses. J Neurosci (2007) 1.12
Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2. J Cell Biol (2009) 1.11
The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions. J Neurosci (2011) 1.11
Naked dense bodies provoke depression. J Neurosci (2010) 1.10
A transcriptional program promotes remodeling of GABAergic synapses in Caenorhabditis elegans. J Neurosci (2011) 1.04
Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo. J Neurosci (2011) 1.04
Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly. Nat Neurosci (2012) 1.04
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth. Proc Natl Acad Sci U S A (2013) 1.04
Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline. Genetics (2008) 1.03
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate. Proc Natl Acad Sci U S A (2012) 1.01
Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex. Proc Natl Acad Sci U S A (2013) 1.01
Two suppressors of sel-12 encode C2H2 zinc-finger proteins that regulate presenilin transcription in Caenorhabditis elegans. Development (2003) 1.00
SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in Caenorhabditis elegans. Nature (2004) 0.99
Insulin/Insulin-like growth factor signaling controls non-Dauer developmental speed in the nematode Caenorhabditis elegans. Genetics (2010) 0.99
Tomosyn negatively regulates both synaptic transmitter and neuropeptide release at the C. elegans neuromuscular junction. J Physiol (2007) 0.98
Caenorhabditis elegans num-1 negatively regulates endocytic recycling. Genetics (2008) 0.98
ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Traffic (2008) 0.98
Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling. Mol Biol Cell (2007) 0.96
A single immunoglobulin-domain protein required for clustering acetylcholine receptors in C. elegans. EMBO J (2011) 0.94
Synaptic vesicle docking: a putative role for the Munc18/Sec1 protein family. Curr Top Dev Biol (2005) 0.94
The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction. Br J Pharmacol (2005) 0.94
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2012) 0.93
Mos1 transposition as a tool to engineer the Caenorhabditis elegans genome by homologous recombination. Methods (2009) 0.92
Liprin-α/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans. J Cell Biol (2013) 0.91
The quantitative nuclear matrix proteome as a biochemical snapshot of nuclear organization. J Proteome Res (2014) 0.91
Regulation of gephyrin assembly and glycine receptor synaptic stability. J Biol Chem (2006) 0.91
An organelle gatekeeper function for Caenorhabditis elegans UNC-16 (JIP3) at the axon initial segment. Genetics (2013) 0.89
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J (2013) 0.88
Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1. Front Synaptic Neurosci (2010) 0.88
An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans. PLoS Genet (2010) 0.88
Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter. Proc Natl Acad Sci U S A (2012) 0.88
Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory. Proc Natl Acad Sci U S A (2011) 0.87
N-wasp is required for stabilization of podocyte foot processes. J Am Soc Nephrol (2013) 0.87
Electrophysiological methods for Caenorhabditis elegans neurobiology. Methods Cell Biol (2012) 0.87
Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans. Mol Cell Neurosci (2010) 0.86
Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit. Nat Neurosci (2012) 0.85
Establishing and sculpting the synapse in Drosophila and C. elegans. Curr Opin Neurobiol (2002) 0.84
The dystrophin-associated protein complex maintains muscle excitability by regulating Ca(2+)-dependent K(+) (BK) channel localization. J Biol Chem (2011) 0.84
TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. PLoS Genet (2012) 0.82
The P-type ATPase CATP-1 is a novel regulator of C. elegans developmental timing that acts independently of its predicted pump function. Development (2007) 0.82
In vivo synaptic recovery following optogenetic hyperstimulation. Proc Natl Acad Sci U S A (2013) 0.82
A novel CaM kinase II pathway controls the location of neuropeptide release from Caenorhabditis elegans motor neurons. Genetics (2014) 0.81
[C. elegans: of neurons and genes]. Med Sci (Paris) (2003) 0.81
Manipulating the Caenorhabditis elegans genome using mariner transposons. Genetica (2009) 0.81
Differential roles for snapin and synaptotagmin in the synaptic vesicle cycle. PLoS One (2013) 0.80
Genome engineering by transgene-instructed gene conversion in C. elegans. Methods Cell Biol (2011) 0.79
In vivo analysis of conserved C. elegans tomosyn domains. PLoS One (2011) 0.77
The complexity of role balance: support for the Model of Juggling Occupations. Scand J Occup Ther (2014) 0.77
Proteolytic processing of the extracellular scaffolding protein LEV-9 is required for clustering acetylcholine receptors. J Biol Chem (2014) 0.76
Knock it down, switch it on. Nat Methods (2010) 0.75
[The sleeping worm?]. Med Sci (Paris) (2008) 0.75