Published in World J Gastroenterol on November 01, 2004
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First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors. J Clin Oncol (2011) 4.53
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Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma. J Clin Oncol (2012) 3.08
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A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells. Cell Stem Cell (2013) 2.68
Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res (2005) 2.42
Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo. Cancer Res (2007) 2.31
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The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients. Clin Cancer Res (2005) 2.14
Role of health insurance in averting economic hardship in families after acute stroke in China. Stroke (2009) 2.13
eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206. Cancer Res (2011) 2.10
Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria. J Bacteriol (2009) 1.96
CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration. Neoplasia (2007) 1.91
Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther (2010) 1.90
Spatial Pyramid Pooling in Deep Convolutional Networks for Visual Recognition. IEEE Trans Pattern Anal Mach Intell (2015) 1.78
TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. J Clin Invest (2009) 1.76
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B. J Hepatol (2011) 1.74
Structural prediction and phase transformation mechanisms in calcium at high pressure. Phys Rev Lett (2009) 1.73
Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN. Mol Cancer Res (2004) 1.73
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Identification of influenza A nucleoprotein as an antiviral target. Nat Biotechnol (2010) 1.71
Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes. J Bacteriol (2009) 1.64
Quantitative analysis of HBV DNA level and HBeAg titer in hepatitis B surface antigen positive mothers and their babies: HBeAg passage through the placenta and the rate of decay in babies. J Med Virol (2003) 1.63
Model consisting of ultrasonographic and simple blood indexes accurately identify compensated hepatitis B cirrhosis. J Gastroenterol Hepatol (2008) 1.58
Surgical treatment strategies in chronic pancreatitis: a meta-analysis. Arch Surg (2012) 1.54
Effect of a novel inhibitory mAb against beta-subunit of F1F0 ATPase on HCC. Cancer Biol Ther (2008) 1.54
Passive smoke exposure and risk of diabetes: a meta-analysis of prospective studies. Endocrine (2014) 1.52
Benzyl 3-[(E)-1-(pyrazin-2-yl)ethyl-idene]dithio-carbazate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.50
miR-23a promotes the transition from indolent to invasive colorectal cancer. Cancer Discov (2012) 1.49
Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway. Mol Cancer Res (2006) 1.45
Color doppler hemodynamic study of the superficial temporal arteries in superficial temporal artery-middle cerebral artery (STA-MCA) bypass surgery for Moyamoya disease. World Neurosurg (2011) 1.43
Blood lymphocyte-to-monocyte ratio identifies high-risk patients in diffuse large B-cell lymphoma treated with R-CHOP. PLoS One (2012) 1.42
Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim. J Biol Chem (2006) 1.41
Synthesis and characterization of ester-derivatized tetrathiatriarylmethyl radicals as intracellular oxygen probes. J Org Chem (2008) 1.40
Learning to detect a salient object. IEEE Trans Pattern Anal Mach Intell (2011) 1.39
Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses (2007) 1.39
Structural insight into RNA hairpin folding intermediates. J Am Chem Soc (2008) 1.39
Single Image Haze Removal Using Dark Channel Prior. IEEE Trans Pattern Anal Mach Intell (2010) 1.36
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway. PLoS One (2013) 1.34
MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis. Mol Cancer Ther (2011) 1.33
Esterified trityl radicals as intracellular oxygen probes. Free Radic Biol Med (2008) 1.31
Distribution of enteroviruses in hospitalized children with hand, foot and mouth disease and relationship between pathogens and nervous system complications. Virol J (2012) 1.30
Image inpainting by patch propagation using patch sparsity. IEEE Trans Image Process (2010) 1.27
microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. J Biol Chem (2010) 1.27
Head and neck inflammatory myofibroblastic tumor (IMT): evaluation of clinicopathologic and prognostic features. Oral Oncol (2011) 1.25
High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma. J Exp Clin Cancer Res (2013) 1.24
Expression profile of cancer-testis genes in 121 human colorectal cancer tissue and adjacent normal tissue. Clin Cancer Res (2005) 1.24
Effects of puerarin on number and activity of endothelial progenitor cells from peripheral blood. Acta Pharmacol Sin (2004) 1.24
Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction. Am J Pathol (2005) 1.24
CXCR6 upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma. Cancer Res (2012) 1.23
Distribution and clinical correlates of viral and host genotypes in Chinese patients with chronic hepatitis C virus infection. J Gastroenterol Hepatol (2014) 1.23
DNA hypermethylation of microRNA-34b/c has prognostic value for stage Ⅰ non-small cell lung cancer. Cancer Biol Ther (2011) 1.22
Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors. J Hematol Oncol (2014) 1.20
A novel multi-aperture based sun sensor based on a fast multi-point MEANSHIFT (FMMS) algorithm. Sensors (Basel) (2011) 1.20
MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma. Biochem Biophys Res Commun (2012) 1.20
Generation, characterization and biological activity of CCL2 (MCP-1/JE) and CCL12 (MCP-5) specific antibodies. Hum Antibodies (2007) 1.19
HIV incidence among men who have sex with men in Beijing: a prospective cohort study. BMJ Open (2012) 1.19
Dissecting the THz spectrum of liquid water from first principles via correlations in time and space. Proc Natl Acad Sci U S A (2010) 1.18
Comparing directly measured standard gamble scores to HUI2 and HUI3 utility scores: group- and individual-level comparisons. Soc Sci Med (2004) 1.17
Evaluation of the 4q32-34 locus in European familial pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.16
The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA. Neuron (2010) 1.16
Anti-EMMPRIN monoclonal antibody as a novel agent for therapy of head and neck cancer. Clin Cancer Res (2009) 1.16
Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model. Biomaterials (2007) 1.15
Targeting the PI3K-AKT-mTOR signaling network in cancer. Chin J Cancer (2013) 1.15
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry (2003) 1.15
Cohort profile: risk evaluation of cancers in Chinese diabetic individuals: a longitudinal (REACTION) study. J Diabetes (2014) 1.15
Action mechanisms of du-huo-ji-sheng-tang on cartilage degradation in a rabbit model of osteoarthritis. Evid Based Complement Alternat Med (2011) 1.14
Willingness to accept HIV pre-exposure prophylaxis among Chinese men who have sex with men. PLoS One (2012) 1.14
Physiologically based synthetic models of hepatic disposition. J Pharmacokinet Pharmacodyn (2006) 1.13
Is the end of the T-tube drainage era in laparoscopic choledochotomy for common bile duct stones is coming? A systematic review and meta-analysis. Ann Surg (2013) 1.13
Epidemiology of eight common rheumatic diseases in China: a large-scale cross-sectional survey in Beijing. Rheumatology (Oxford) (2011) 1.12
miR-29c induces cell cycle arrest in esophageal squamous cell carcinoma by modulating cyclin E expression. Carcinogenesis (2011) 1.12
Synthesis of 14N- and 15N-labeled trityl-nitroxide biradicals with strong spin-spin interaction and improved sensitivity to redox status and oxygen. J Org Chem (2010) 1.11
Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA. Nat Struct Mol Biol (2012) 1.10
Topological methods for exploring low-density states in biomolecular folding pathways. J Chem Phys (2009) 1.10
Peer influences and access to cigarettes as correlates of adolescent smoking: a cross-cultural comparison of Wuhan, China, and California. Prev Med (2002) 1.10
Incidence of malignancy in primary Sjogren's syndrome in a Chinese cohort. Rheumatology (Oxford) (2009) 1.10
Later onset phenotypes of Krabbe disease: results of the world-wide registry. Pediatr Neurol (2012) 1.09
Disruption of the AKT pathway inhibits metastasis in an orthotopic model of head and neck squamous cell carcinoma. Laryngoscope (2011) 1.09
Practical difficulties in the management of hepatitis B in the Asia-Pacific region. J Gastroenterol Hepatol (2004) 1.09
[Effects of puerarin on number and activity of endothelial progenitor cells from peripheral blood]. Zhongguo Zhong Yao Za Zhi (2004) 1.08
The expression of hypoxia-inducible factor-1alpha in hepatitis B virus-related hepatocellular carcinoma: correlation with patients' prognosis and hepatitis B virus X protein. Dig Dis Sci (2008) 1.07
Circulating chemokine (C-X-C Motif) receptor 5(+) CD4(+) T cells benefit hepatitis B e antigen seroconversion through IL-21 in patients with chronic hepatitis B virus infection. Hepatology (2013) 1.07
Effect of inhaled magnesium sulfate on bronchial hyperresponsiveness. Indian J Pediatr (2014) 1.06
Occult hepatitis B virus infection in hematopoietic stem cell donors in a hepatitis B virus endemic area. J Hepatol (2005) 1.06
Protein database, human retinal pigment epithelium. Mol Cell Proteomics (2003) 1.05
Selection of reference genes for real-time PCR in human hepatocellular carcinoma tissues. J Cancer Res Clin Oncol (2008) 1.05
New irrigation methods sustain malaria control in Sichuan Province, China. Acta Trop (2004) 1.05
Cancer stem cell marker CD133+ tumour cells and clinical outcome in rectal cancer. Histopathology (2009) 1.04
Involvement of RAGE, MAPK and NF-κB pathways in AGEs-induced MMP-9 activation in HaCaT keratinocytes. Exp Dermatol (2012) 1.04
ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts. Int J Cancer (2008) 1.03
Toxic effect of gestational exposure to nonylphenol on F1 male rats. Birth Defects Res B Dev Reprod Toxicol (2010) 1.03
Spread of oqxAB in Salmonella enterica serotype Typhimurium predominantly by IncHI2 plasmids. J Antimicrob Chemother (2013) 1.03
Dissemination and characterization of plasmids carrying oqxAB-bla CTX-M genes in Escherichia coli isolates from food-producing animals. PLoS One (2013) 1.03
A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors. Breast Cancer Res (2013) 1.03
MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1. Mol Cancer (2014) 1.03
A serum proteomic pattern for the detection of colorectal adenocarcinoma using surface enhanced laser desorption and ionization mass spectrometry. Cancer Invest (2006) 1.03