eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206.

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Published in Cancer Res on February 09, 2011

Authors

Yan Cheng1, Xingcong Ren, Yi Zhang, Rajesh Patel, Arati Sharma, Hao Wu, Gavin P Robertson, Li Yan, Eric Rubin, Jin-Ming Yang

Author Affiliations

1: Department of Pharmacology and The Penn State Hershey Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

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