Published in Expert Opin Investig Drugs on October 01, 2004
Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes (2007) 2.01
Cystoid macular edema. Clin Ophthalmol (2008) 1.47
The effectiveness of vitrectomy for diffuse diabetic macular edema may depend on its preoperative optical coherence tomography pattern. Graefes Arch Clin Exp Ophthalmol (2016) 1.30
Mediators of ocular angiogenesis. J Genet (2009) 1.17
Diabetic Retinopathy: Vascular and Inflammatory Disease. J Diabetes Res (2015) 1.13
Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. Am J Pathol (2011) 1.12
Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. Am J Pathol (2006) 1.10
Therapeutic effects of PPARα agonists on diabetic retinopathy in type 1 diabetes models. Diabetes (2012) 1.08
PEDF regulates vascular permeability by a γ-secretase-mediated pathway. PLoS One (2011) 1.05
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99
gamma-Secretase: a multifaceted regulator of angiogenesis. J Cell Mol Med (2008) 0.99
Meta-analysis and review on the effect of bevacizumab in diabetic macular edema. Graefes Arch Clin Exp Ophthalmol (2010) 0.92
Neuroinflammatory responses in diabetic retinopathy. J Neuroinflammation (2015) 0.91
Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema. World J Diabetes (2013) 0.89
Usefulness of the vitreous fluid analysis in the translational research of diabetic retinopathy. Mediators Inflamm (2012) 0.89
Good news-bad news: the Yin and Yang of immune privilege in the eye. Front Immunol (2012) 0.88
Attenuation of diabetic retinopathy by enhanced inhibition of MMP-2 and MMP-9 using aspirin and minocycline in streptozotocin-diabetic rats. Am J Transl Res (2010) 0.88
Ranibizumab in the treatment of patients with visual impairment due to diabetic macular edema. Clin Ophthalmol (2011) 0.88
Peripheral retinal function assessed with 30-Hz flicker seems to improve after treatment with Lucentis in patients with diabetic macular oedema. Doc Ophthalmol (2015) 0.86
Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis. Int J Mol Sci (2015) 0.84
The 5-year onset and regression of diabetic retinopathy in Chinese type 2 diabetes patients. PLoS One (2014) 0.83
Intravitreal bevacizumab as anti-vascular endothelial growth factor in the management of complications of proliferative diabetic retinopathy. Med Hypothesis Discov Innov Ophthalmol (2013) 0.83
Anti-tumor necrosis factor alpha for retinal diseases: current knowledge and future concepts. J Ophthalmic Vis Res (2012) 0.81
Structural and functional changes of the human macula during acute exposure to high altitude. PLoS One (2012) 0.79
A five-year prospective study of diabetic retinopathy progression in chinese type 2 diabetes patients with "well-controlled" blood glucose. PLoS One (2015) 0.78
[Ranibizumab in diabetic macular edema. Evaluation of functional and morphological aspects]. Ophthalmologe (2013) 0.78
Combined therapy for diabetic macular edema. Middle East Afr J Ophthalmol (2013) 0.77
P450 in the angiogenesis affair: the unusual suspect. Am J Pathol (2005) 0.77
Efficacy and Safety of Intravitreal Dexamethasone Implants for Treatment of Refractory Diabetic Macular Edema. Korean J Ophthalmol (2017) 0.75
Adaptive Optics Reveals Photoreceptor Abnormalities in Diabetic Macular Ischemia. PLoS One (2017) 0.75
The role of aflibercept in the management of diabetic macular edema. Drug Des Devel Ther (2015) 0.75
Vitrectomy for diabetic macular edema; where are we? J Curr Ophthalmol (2016) 0.75
Influence of baseline diabetic retinopathy status on initial anatomical response of intravitreal ranibizumab therapy for diabetic macular oedema. Eye (Lond) (2017) 0.75
Expression of angiopoietin-like protein 8 correlates with VEGF in patients with proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat Med (2002) 3.81
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes (2007) 2.01
Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes. Diabetes (2006) 1.96
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. FASEB J (2007) 1.94
SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J Clin Invest (2005) 1.84
The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells. Blood (2004) 1.77
IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development. Proc Natl Acad Sci U S A (2007) 1.77
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models. Am J Respir Crit Care Med (2013) 1.71
Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock. J Exp Med (2009) 1.68
The role of adult bone marrow-derived stem cells in choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 1.52
Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas. Int J Cancer (2012) 1.41
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis. J Leukoc Biol (2007) 1.39
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. Free Radic Biol Med (2009) 1.38
Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res (2009) 1.31
Inflammation in the pathogenesis of microvascular complications in diabetes. Front Endocrinol (Lausanne) (2012) 1.24
FXR regulates liver repair after CCl4-induced toxic injury. Mol Endocrinol (2010) 1.23
An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism. Hum Mutat (2008) 1.19
CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. Br J Pharmacol (2010) 1.18
Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. Am J Pathol (2011) 1.12
Adult human hematopoietic cells provide functional hemangioblast activity. Blood (2003) 1.11
Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. Am J Pathol (2006) 1.10
Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors. Invest Ophthalmol Vis Sci (2005) 1.10
Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis (2006) 1.10
EPCs and pathological angiogenesis: when good cells go bad. Microvasc Res (2010) 1.07
Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair. Mol Ther (2009) 1.05
Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Exp Physiol (2011) 1.04
Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke. Neuropharmacology (2013) 1.04
Beneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat. Mediators Inflamm (2011) 1.04
CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex. PLoS Pathog (2012) 1.03
Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res (2012) 1.01
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Invest Ophthalmol Vis Sci (2011) 1.00
Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization. Exp Eye Res (2008) 0.99
Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization. Am J Pathol (2006) 0.98
Outbreak of scarlet fever associated with emm12 type group A Streptococcus in 2011 in Shanghai, China. Pediatr Infect Dis J (2012) 0.97
Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma. Med Oncol (2010) 0.97
Comparative epidemiology and virology of fatal and nonfatal cases of hand, foot and mouth disease in mainland China from 2008 to 2014. Rev Med Virol (2015) 0.97
Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.96
Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci (2004) 0.96
The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci (2006) 0.95
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension. Hypertension (2012) 0.95
Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow. Diabetes (2012) 0.95
Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase. Invest Ophthalmol Vis Sci (2003) 0.94
Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes. Diabetes (2012) 0.94
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat. Hypertension (2013) 0.93
Focal adhesion kinase overexpression induces enhanced pathological retinal angiogenesis. Invest Ophthalmol Vis Sci (2004) 0.93
Endothelial progenitor dysfunction in the pathogenesis of diabetic retinopathy: treatment concept to correct diabetes-associated deficits. EPMA J (2010) 0.92
Expression of IGFBP-3 by human retinal endothelial cell cultures: IGFBP-3 involvement in growth inhibition and apoptosis. Invest Ophthalmol Vis Sci (2003) 0.91
Further analysis of interpolation effects in mutual information-based image registration. IEEE Trans Med Imaging (2003) 0.91
Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3. PLoS One (2012) 0.91
Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats. J Pharmacol Exp Ther (2007) 0.91
Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1. Cancer Res (2012) 0.91
Intraluminal middle cerebral artery occlusion (MCAO) model for ischemic stroke with laser doppler flowmetry guidance in mice. J Vis Exp (2011) 0.90
Fabrication of carvedilol nanosuspensions through the anti-solvent precipitation-ultrasonication method for the improvement of dissolution rate and oral bioavailability. AAPS PharmSciTech (2012) 0.89
The contribution of adult hematopoietic stem cells to retinal neovascularization. Adv Exp Med Biol (2003) 0.89
Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α. Int J Cancer (2014) 0.88
Effects of VEGFR-1, VEGFR-2, and IGF-IR hammerhead ribozymes on glucose-mediated tight junction expression in cultured human retinal endothelial cells. Mol Vis (2006) 0.87
Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model. Oncol Rep (2013) 0.87
LC3B-II deacetylation by histone deacetylase 6 is involved in serum-starvation-induced autophagic degradation. Biochem Biophys Res Commun (2013) 0.86
Intravenous lipid emulsions combine extracorporeal blood purification: a novel therapeutic strategy for severe organophosphate poisoning. Med Hypotheses (2009) 0.85
Labeling of stem cells with monocrystalline iron oxide for tracking and localization by magnetic resonance imaging. Microvasc Res (2009) 0.85
A serological and molecular survey of hepatitis B in children 15 years after inception of the national hepatitis B vaccination program in eastern China. J Med Virol (2009) 0.84
The two enantiomers of tetrahydropalmatine are inhibitors of P-gp, but not inhibitors of MRP1 or BCRP. Xenobiotica (2012) 0.84
Effect of hepatocyte growth-promoting factors on myocardial ischemia during exercise in patients with severe coronary artery disease. Int Heart J (2009) 0.84
Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy. Food Chem Toxicol (2013) 0.84
Influence of calcination temperature on the performance of Pd-Mn/SiO2-Al2O3 catalysts for ozone decomposition. J Hazard Mater (2009) 0.84
Role of catechol-O-methyltransferase in the disposition of luteolin in rats. Drug Metab Dispos (2011) 0.84
The critical molecular interconnections in regulating apoptosis and autophagy. Ann Med (2015) 0.83
Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line. Oncol Rep (2012) 0.83
Pulmonary complications in patients with chronic obstructive pulmonary disease following transthoracic esophagectomy. World J Gastroenterol (2006) 0.83
Novel surface-modified nanostructured lipid carriers with partially deacetylated water-soluble chitosan for efficient ocular delivery. J Pharm Sci (2011) 0.83
Patterns of polymorphism and divergence in the VP1 gene of enterovirus 71 circulating in the Asia-Pacific region between 1994 and 2013. J Virol Methods (2013) 0.82
Rapid membrane effect of testosterone in LNCaP cells. Urol Int (2008) 0.82
The population-based health effect of hand, foot and mouth disease in children in Shanghai. Pediatr Infect Dis J (2014) 0.82
A simple parallel analytical method of prenatal screening. Gynecol Obstet Invest (2006) 0.81
ERK and PI3K signaling cascades induce Nrf2 activation and regulate cell viability partly through Nrf2 in human glioblastoma cells. Oncol Rep (2013) 0.81
Synergistic manipulation of micro-nanostructures and composition: anatase/rutile mixed-phase TiO2 hollow micro-nanospheres with hierarchical mesopores for photovoltaic and photocatalytic applications. Nanotechnology (2011) 0.81
Design and evaluation of baicalin-containing in situ pH-triggered gelling system for sustained ophthalmic drug delivery. Int J Pharm (2011) 0.80
Sulphoraphane enhances aquaporin-4 expression and decreases spinal cord oedema following spinal cord injury. Brain Inj (2011) 0.79
[Mechanism of cardioprotection induced by noninvasive limb ischemic preconditioning]. Zhonghua Yi Xue Za Zhi (2009) 0.79
Effect of endothelin-1 in esophageal squamous cell carcinoma invasion and its correlation with cathepsin B. World J Gastroenterol (2007) 0.79
Decreased expression of the insulin-like growth factor 1 receptor by ribozyme cleavage. Invest Ophthalmol Vis Sci (2003) 0.79
Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganese. Drug Metab Dispos (2011) 0.79
A rapid method for the quantification of GSH and GSSG in biological samples. Methods Mol Biol (2002) 0.79