Published in Cell on March 20, 1992
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Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell (2008) 5.60
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Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling. Proc Natl Acad Sci U S A (1999) 1.14
A deficiency screen for zygotic loci required for establishment and patterning of the epidermis in Caenorhabditis elegans. Genetics (1997) 1.13
The nuclear protein encoded by the Drosophila neurogenic gene mastermind is widely expressed and associates with specific chromosomal regions. Genetics (1996) 1.12
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. Elife (2015) 1.12
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Genetic mechanisms of coffee extract protection in a Caenorhabditis elegans model of β-amyloid peptide toxicity. Genetics (2010) 1.08
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Knockdown of SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification in C. briggsae as compared with C. elegans. Dev Biol (2008) 1.04
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Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain-of-function allele. EMBO J (2002) 1.02
Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network. Dev Biol (2009) 1.01
The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development. Development (2009) 1.01
De novo inference of systems-level mechanistic models of development from live-imaging-based phenotype analysis. Cell (2014) 1.01
Life-span extension from hypoxia in Caenorhabditis elegans requires both HIF-1 and DAF-16 and is antagonized by SKN-1. J Gerontol A Biol Sci Med Sci (2013) 1.01
Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans. Dev Biol (2005) 1.00
Conditional dominant mutations in the Caenorhabditis elegans gene act-2 identify cytoplasmic and muscle roles for a redundant actin isoform. Mol Biol Cell (2006) 0.99
Reevaluation of the role of the med-1 and med-2 genes in specifying the Caenorhabditis elegans endoderm. Genetics (2005) 0.99
SKN-1 domain folding and basic region monomer stabilization upon DNA binding. Genes Dev (1997) 0.98
SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans. Free Radic Biol Med (2015) 0.98
A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative stress adaptation in mammals, Caenorhabditis elegans and Drosophila melanogaster. J Exp Biol (2012) 0.96
Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress. Mol Cell Biol (2012) 0.94
Transgenerational epigenetics in the germline cycle of Caenorhabditis elegans. Epigenetics Chromatin (2014) 0.94
The SKN-1 amino-terminal arm is a DNA specificity segment. Mol Cell Biol (1999) 0.92
Polarity and cell fate specification in the control of Caenorhabditis elegans gastrulation. Dev Dyn (2009) 0.91
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol (2004) 0.91
Pinewood nematode-associated bacteria contribute to oxidative stress resistance of Bursaphelenchus xylophilus. BMC Microbiol (2013) 0.90
Transcription reactivation steps stimulated by oocyte maturation in C. elegans. Dev Biol (2006) 0.90
An ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegans. PLoS One (2013) 0.90
Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance. Drug Metab Rev (2012) 0.90
unc-44 Ankyrin and stn-2 gamma-syntrophin regulate sax-7 L1CAM function in maintaining neuronal positioning in Caenorhabditis elegans. Genetics (2008) 0.89
Integrative analysis of C. elegans modENCODE ChIP-seq data sets to infer gene regulatory interactions. Genome Res (2013) 0.89
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1. Elife (2016) 0.89
SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network. EMBO J (2010) 0.88
The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity. Sci Rep (2013) 0.88
HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans. PLoS One (2011) 0.87
Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans. FASEB J (2009) 0.87
mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity. Aging Cell (2014) 0.86
Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans. Genetics (2011) 0.86
MED GATA factors promote robust development of the C. elegans endoderm. Dev Biol (2015) 0.85
Uncoupling different characteristics of the C. elegans E lineage from differentiation of intestinal markers. PLoS One (2014) 0.84
The study of Priapulus caudatus reveals conserved molecular patterning underlying different gut morphogenesis in the Ecdysozoa. BMC Biol (2015) 0.84
C. elegans pur alpha, an activator of end-1, synergizes with the Wnt pathway to specify endoderm. Dev Biol (2008) 0.84
Effects of chromosomal deficiencies on early cleavage patterning and terminal phenotype in Caenorhabditis elegans embryos. Genetics (1994) 0.83
Collaborative regulation of development but independent control of metabolism by two epidermis-specific transcription factors in Caenorhabditis elegans. J Biol Chem (2013) 0.82
Omega-3 and -6 fatty acids allocate somatic and germline lipids to ensure fitness during nutrient and oxidative stress in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2015) 0.82
Mitochondria and metazoan epigenesis. Semin Cell Dev Biol (2009) 0.82
Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf. Sci Rep (2016) 0.82
E3 ubiquitin ligases promote progression of differentiation during C. elegans embryogenesis. Dev Biol (2014) 0.82
Reduced dosage of pos-1 suppresses Mex mutants and reveals complex interactions among CCCH zinc-finger proteins during Caenorhabditis elegans embryogenesis. Genetics (2006) 0.82
Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors. PLoS One (2013) 0.81
Constitutive activation of the Nrf2/Keap1 pathway in insecticide-resistant strains of Drosophila. Insect Biochem Mol Biol (2013) 0.81
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Selective lineage specification by mab-19 during Caenorhabditis elegans male peripheral sense organ development. Genetics (1994) 0.81
Retracted A negative-feedback loop between the detoxification/antioxidant response factor SKN-1 and its repressor WDR-23 matches organism needs with environmental conditions. Mol Cell Biol (2013) 0.80
The solution structure of the DNA-binding domain of Skn-1. Proc Natl Acad Sci U S A (1998) 0.80
Effects and mechanisms of prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans. Aging Cell (2015) 0.80
Dynamics and recognition within a protein-DNA complex: a molecular dynamics study of the SKN-1/DNA interaction. Nucleic Acids Res (2015) 0.79
Subdivision of arthropod cap-n-collar expression domains is restricted to Mandibulata. Evodevo (2014) 0.79
TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development. Dev Biol (2013) 0.79
The near demise and subsequent revival of classical genetics for investigating Caenorhabditis elegans embryogenesis: RNAi meets next-generation DNA sequencing. Mol Biol Cell (2011) 0.78
Transcription factor redundancy and tissue-specific regulation: evidence from functional and physical network connectivity. Genome Res (2012) 0.78
Retracted Direct interaction between the WD40 repeat protein WDR-23 and SKN-1/Nrf inhibits binding to target DNA. Mol Cell Biol (2014) 0.78
Cap'n'collar differentiates the mandible from the maxilla in the beetle Tribolium castaneum. Evodevo (2012) 0.76
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Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance. G3 (Bethesda) (2015) 0.75
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Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos. Cell (1997) 4.61
Caenorhabditis elegans morphogenesis: the role of the cytoskeleton in elongation of the embryo. Dev Biol (1986) 3.12
WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. Cell (1999) 2.69
pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell (1995) 2.61
A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J Cell Biol (1998) 2.61
Repression of gene expression in the embryonic germ lineage of C. elegans. Nature (1996) 2.51
The PIE-1 protein and germline specification in C. elegans embryos. Nature (1996) 2.46
POP-1 and anterior-posterior fate decisions in C. elegans embryos. Cell (1998) 2.31
par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3. Development (1996) 2.31
end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos. Genes Dev (1997) 2.22
Cellular interactions in early C. elegans embryos. Cell (1987) 2.15
Organogenesis of the Caenorhabditis elegans intestine. Dev Biol (1999) 2.10
MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos. Cell (1996) 2.08
unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration. Development (2001) 2.08
MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos. Mol Cell (2000) 1.93
P granules in the germ cells of Caenorhabditis elegans adults are associated with clusters of nuclear pores and contain RNA. Dev Biol (2000) 1.91
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos. Cell (1993) 1.90
Analysis of RNA associated with P granules in germ cells of C. elegans adults. Development (2001) 1.87
pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans. Development (1999) 1.80
Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements. Science (1994) 1.68
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos. Cell (1992) 1.66
The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo. Cell (1994) 1.55
The C. elegans MEX-1 protein is present in germline blastomeres and is a P granule component. Development (1997) 1.50
The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling. Mol Cell (2001) 1.46
The role of actin filaments in patterning the Caenorhabditis elegans cuticle. Dev Biol (1997) 1.43
BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions. J Virol (1991) 1.33
ELT-1, a GATA-like transcription factor, is required for epidermal cell fates in Caenorhabditis elegans embryos. Genes Dev (1997) 1.25
An inductive interaction in 4-cell stage C. elegans embryos involves APX-1 expression in the signalling cell. Development (1996) 1.08
Left-right asymmetry in C. elegans intestine organogenesis involves a LIN-12/Notch signaling pathway. Development (2000) 1.05
aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling. Development (2000) 1.00
Cell interactions involved in development of the bilaterally symmetrical intestinal valve cells during embryogenesis in Caenorhabditis elegans. Development (1992) 0.89
Biosynthesis and secretion of pituitary hormones: dynamics and regulation. Arch Physiol Biochem (2002) 0.85
Localization of the apex of the vagina: implications for radiation therapy planning. Radiology (1999) 0.77