Published in Cell Cycle on November 10, 2004
Lithium causes G2 arrest of renal principal cells. J Am Soc Nephrol (2014) 1.26
BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells. Blood Cells Mol Dis (2008) 1.21
Toxic effect of silica nanoparticles on endothelial cells through DNA damage response via Chk1-dependent G2/M checkpoint. PLoS One (2013) 1.06
The substrates of Plk1, beyond the functions in mitosis. Protein Cell (2010) 0.97
Molecular Pathways: Targeting ATR in Cancer Therapy. Clin Cancer Res (2015) 0.90
Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol (2008) 0.90
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner. PLoS One (2014) 0.89
Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling. EMBO J (2012) 0.81
ATP depletion triggers acute myeloid leukemia differentiation through an ATR/Chk1 protein-dependent and p53 protein-independent pathway. J Biol Chem (2012) 0.76
Combined Effect of Silica Nanoparticles and Benzo[a]pyrene on Cell Cycle Arrest Induction and Apoptosis in Human Umbilical Vein Endothelial Cells. Int J Environ Res Public Health (2017) 0.75
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A (2009) 7.95
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A (2010) 6.15
Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol (2002) 5.74
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A (2007) 4.97
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A (2003) 4.69
Modelling breast cancer: one size does not fit all. Nat Rev Cancer (2007) 3.64
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res (2008) 3.45
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A (2011) 3.40
Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell (2004) 2.94
On mammary stem cells. J Cell Sci (2005) 2.56
An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res (2009) 2.37
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A (2011) 2.01
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.00
Selective targeting of radiation-resistant tumor-initiating cells. Proc Natl Acad Sci U S A (2010) 1.99
Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci (2007) 1.98
A noncoding RNA is a potential marker of cell fate during mammary gland development. Proc Natl Acad Sci U S A (2006) 1.94
Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol (2005) 1.81
Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev (2005) 1.80
FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res (2013) 1.76
Minireview: hormones and mammary cell fate--what will I become when I grow up? Endocrinology (2008) 1.71
Will cancer stem cells provide new therapeutic targets? Carcinogenesis (2004) 1.64
Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol (2002) 1.61
The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol (2003) 1.47
A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci (2010) 1.47
Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med (2010) 1.43
The role of C/EBPbeta in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia (2003) 1.38
Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol (2002) 1.37
A beta-catenin survival signal is required for normal lobular development in the mammary gland. J Cell Sci (2003) 1.34
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol (2013) 1.30
Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium. Mol Endocrinol (2002) 1.30
Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Genomics (2003) 1.29
p190-B RhoGAP regulates mammary ductal morphogenesis. Mol Endocrinol (2003) 1.23
The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis. Proc Natl Acad Sci U S A (2009) 1.22
Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia (2005) 1.22
Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Mol Endocrinol (2007) 1.19
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res (2003) 1.18
Hormone dependence in premalignant mammary progression. Cancer Res (2003) 1.16
Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res (2013) 1.16
The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. RNA Biol (2010) 1.15
Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Res (2009) 1.15
Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Mol Endocrinol (2006) 1.13
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep (2013) 1.13
P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Mol Endocrinol (2006) 1.11
Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cells. FASEB J (2006) 1.11
Keratin 6 is not essential for mammary gland development. Breast Cancer Res (2006) 1.10
A critical role for the inflammatory response in a mouse model of preneoplastic progression. Cancer Res (2006) 1.09
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A (2010) 1.09
CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells (2010) 1.08
Wnt and mammary stem cells: hormones cannot fly wingless. Curr Opin Pharmacol (2010) 1.08
Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res (2010) 1.07
Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage. Breast Cancer Res (2007) 1.06
An inducible system for the study of FGF signalling in early amphibian development. Dev Biol (2003) 1.05
Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol (2007) 1.04
Transcriptional profiling of mammary gland side population cells. Stem Cells (2005) 1.02
The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia (2010) 1.02
Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. J Biol Chem (2009) 1.01
Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b. J Biol Chem (2003) 1.01
Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol Cell Biol (2011) 1.00
STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells (2014) 0.99
P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Res (2010) 0.98
Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function. Stem Cells (2013) 0.97
Mammary gland macrophages: pleiotropic functions in mammary development. J Mammary Gland Biol Neoplasia (2006) 0.97
Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol (2006) 0.97
Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem (2005) 0.96
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol (2011) 0.96
Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One (2012) 0.95
Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res (2003) 0.95
Small players with big roles: microRNAs as targets to inhibit breast cancer progression. Curr Drug Targets (2010) 0.93
The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development. Mol Endocrinol (2002) 0.93
Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Breast Cancer Res (2009) 0.93
Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go. J Mammary Gland Biol Neoplasia (2012) 0.92
Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. PLoS Genet (2012) 0.90
Chking and executing cell division to prevent genomic instability. Cell Cycle (2009) 0.90
Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res (2012) 0.90
Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Mol Endocrinol (2011) 0.89
Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One (2010) 0.89
Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating. Breast Cancer Res (2006) 0.89
Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer. Breast Cancer Res Treat (2015) 0.88
Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? Breast Cancer Res (2014) 0.88
The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression. Cell Cycle (2011) 0.88
Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One (2011) 0.85
Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model. Cancer Biol Ther (2011) 0.84
Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival. Mol Cancer Res (2003) 0.84
Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cells Transl Med (2013) 0.84
Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res (2011) 0.79
Plk2 regulates mitotic spindle orientation and mammary gland development. Development (2014) 0.78
The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells. Biochem Biophys Res Commun (2007) 0.77
The chromatin landscape of the casein gene locus. Horm Mol Biol Clin Investig (2012) 0.76
Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination. Breast Cancer Res (2013) 0.75
Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol (2016) 0.75
Mammary gland development & breast cancer; connecting the dots by non-coding RNAs. J Mammary Gland Biol Neoplasia (2012) 0.75