Published in Proc Natl Acad Sci U S A on March 30, 2006
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
Long noncoding RNAs: functional surprises from the RNA world. Genes Dev (2009) 9.14
Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci U S A (2008) 7.19
The genetic signatures of noncoding RNAs. PLoS Genet (2009) 6.72
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Res (2008) 6.43
The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol (2012) 5.60
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
Noncoding RNA in development. Mamm Genome (2008) 3.42
The rise of regulatory RNA. Nat Rev Genet (2014) 3.02
Genome-wide computational identification and manual annotation of human long noncoding RNA genes. RNA (2010) 2.85
RNAdb 2.0--an expanded database of mammalian non-coding RNAs. Nucleic Acids Res (2006) 2.27
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression. Cell Death Dis (2014) 2.09
Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer. Stem Cells (2008) 1.96
Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. Oncotarget (2014) 1.90
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA (2009) 1.78
On the classification of long non-coding RNAs. RNA Biol (2013) 1.53
The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol (2011) 1.43
Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer. Am J Transl Res (2012) 1.33
Non-coding RNAs: multi-tasking molecules in the cell. Int J Mol Sci (2013) 1.07
Non-protein coding RNA biomarkers and differential expression in cancers: a review. J Exp Clin Cancer Res (2008) 1.06
Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57. Cell Death Dis (2016) 1.06
Low expression of long noncoding RNA PANDAR predicts a poor prognosis of non-small cell lung cancer and affects cell apoptosis by regulating Bcl-2. Cell Death Dis (2015) 1.04
Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. RNA Biol (2014) 1.03
The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia (2010) 1.02
Conserved introns reveal novel transcripts in Drosophila melanogaster. Genome Res (2009) 1.01
Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer. J Exp Clin Cancer Res (2013) 1.01
Hormone-regulated transcriptomes: lessons learned from estrogen signaling pathways in breast cancer cells. Mol Cell Endocrinol (2013) 0.99
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease. Endocr Rev (2014) 0.98
Long non-coding RNAs as regulators of the endocrine system. Nat Rev Endocrinol (2015) 0.93
Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer. Oncotarget (2016) 0.92
Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs. Nat Commun (2015) 0.92
Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go. J Mammary Gland Biol Neoplasia (2012) 0.92
MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361. PLoS Genet (2014) 0.91
Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. PLoS Genet (2012) 0.90
A new 'Linc' between noncoding RNAs and blood development. Genes Dev (2011) 0.89
The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms. PLoS One (2012) 0.87
Keeping abreast with long non-coding RNAs in mammary gland development and breast cancer. Front Genet (2014) 0.87
Spatiotemporal expression pattern of Mirg, an imprinted non-coding gene, during mouse embryogenesis. J Mol Histol (2011) 0.85
E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs. Oncotarget (2016) 0.85
Minireview: Long noncoding RNAs: new "links" between gene expression and cellular outcomes in endocrinology. Mol Endocrinol (2013) 0.83
Identification of protein-coding and non-coding RNA expression profiles in CD34+ and in stromal cells in refractory anemia with ringed sideroblasts. BMC Med Genomics (2010) 0.82
Genome-Wide Discovery of Long Non-Coding RNAs in Rainbow Trout. PLoS One (2016) 0.81
Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol (2014) 0.79
Integrated host and viral transcriptome analyses reveal pathology and inflammatory response mechanisms to ALV-J injection in SPF chickens. Sci Rep (2017) 0.79
The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873. Cell Death Differ (2016) 0.78
Transcription of mouse Sp2 yields alternatively spliced and sub-genomic mRNAs in a tissue- and cell-type-specific fashion. Biochim Biophys Acta (2010) 0.78
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma. Nucleic Acids Res (2016) 0.77
The chromatin landscape of the casein gene locus. Horm Mol Biol Clin Investig (2012) 0.76
Identification and characterization of long intergenic noncoding RNAs in bovine mammary glands. BMC Genomics (2017) 0.75
LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. Sci Rep (2016) 0.75
Transcriptome analysis of coding and long non-coding RNAs highlights the regulatory network of cascade initiation of permanent molars in miniature pigs. BMC Genomics (2017) 0.75
Mammary gland stem cells and their application in breast cancer. Oncotarget (2016) 0.75
Challenging paradigms: long non-coding RNAs in breast ductal carcinoma in situ (DCIS). Front Genet (2013) 0.75
‘The charmingest place’: non-coding RNA, lineage tracing, tumor heterogeneity, metastasis and metabolism--new methods in mammary gland development and cancer: the fifth ENBDC Workshop. Breast Cancer Res (2013) 0.75
Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells. Cell Death Discov (2017) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
A uniform system for microRNA annotation. RNA (2003) 20.28
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell (2004) 16.15
Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet (2005) 15.96
Identification of mammalian microRNA host genes and transcription units. Genome Res (2004) 14.63
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science (2005) 9.25
Non-coding RNA genes and the modern RNA world. Nat Rev Genet (2001) 9.06
Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22. Genome Res (2004) 8.35
An expanding universe of noncoding RNAs. Science (2002) 5.96
Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat Genet (2003) 5.38
Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep (2001) 4.74
Challenging the dogma: the hidden layer of non-protein-coding RNAs in complex organisms. Bioessays (2003) 3.59
Antisense transcripts with FANTOM2 clone set and their implications for gene regulation. Genome Res (2003) 3.40
An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal. Development (2002) 3.16
Retracted Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature (2004) 3.12
Mouse transcriptome: neutral evolution of 'non-coding' complementary DNAs. Nature (2004) 3.00
A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell (2004) 2.95
Mammary ductal elongation: differentiation of myoepithelium and basal lamina during branching morphogenesis. Dev Biol (1983) 2.95
Prolactin regulation of beta-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line. EMBO J (1988) 2.82
Identification of putative noncoding RNAs among the RIKEN mouse full-length cDNA collection. Genome Res (2003) 2.63
The functional genomics of noncoding RNA. Science (2005) 2.33
C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development. Mol Endocrinol (2000) 2.11
Systematic expression profiling of the mouse transcriptome using RIKEN cDNA microarrays. Genome Res (2003) 1.98
Fewer genes, more noncoding RNA. Science (2005) 1.84
Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling. Genome Res (2003) 1.82
Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol (2005) 1.81
Chromatin remodeling in development and differentiation. Curr Opin Genet Dev (2001) 1.56
Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy. Proc Natl Acad Sci U S A (1999) 1.56
Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction. Methods Enzymol (2002) 1.41
Mouse-centric comparative transcriptomics of protein coding and non-coding RNAs. Bioessays (2004) 1.36
p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A (2001) 1.35
A beta-catenin survival signal is required for normal lobular development in the mammary gland. J Cell Sci (2003) 1.34
Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis (1998) 1.31
Persistent changes in gene expression induced by estrogen and progesterone in the rat mammary gland. Mol Endocrinol (2001) 1.21
Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci (2001) 1.08
Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res (2003) 0.95
Expression and function of CCAAT/enhancer binding proteinbeta (C/EBPbeta) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells. J Cell Biochem (2001) 0.94
Mammary gland development, reproductive history, and breast cancer risk. Cancer Res (1999) 0.93
The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A (2009) 7.95
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A (2010) 6.15
Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol (2002) 5.74
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A (2007) 4.97
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A (2003) 4.69
Modelling breast cancer: one size does not fit all. Nat Rev Cancer (2007) 3.64
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res (2008) 3.45
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A (2011) 3.40
Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell (2004) 2.94
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res (2013) 2.63
On mammary stem cells. J Cell Sci (2005) 2.56
An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res (2009) 2.37
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A (2011) 2.01
Cavernoma-related epilepsy: review and recommendations for management--report of the Surgical Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia (2013) 2.00
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.00
Selective targeting of radiation-resistant tumor-initiating cells. Proc Natl Acad Sci U S A (2010) 1.99
Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci (2007) 1.98
Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol (2005) 1.81
Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev (2005) 1.80
The bovine lactation genome: insights into the evolution of mammalian milk. Genome Biol (2009) 1.77
FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res (2013) 1.76
Minireview: hormones and mammary cell fate--what will I become when I grow up? Endocrinology (2008) 1.71
Proposal: different types of alteration and loss of consciousness in epilepsy. Epilepsia (2014) 1.66
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res (2008) 1.66
Will cancer stem cells provide new therapeutic targets? Carcinogenesis (2004) 1.64
Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol (2002) 1.61
Inappropriate prescribing in an older ED population. Am J Emerg Med (2007) 1.48
The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol (2003) 1.47
A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci (2010) 1.47
Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med (2010) 1.43
Immediate and short-term outcomes after percutaneous atrial septal defect closure using the new nit-occlud ASD-R device. Catheter Cardiovasc Interv (2014) 1.42
Preoperative magnetic resonance imaging in Type 2 trigeminal neuralgia. J Neurosurg (2010) 1.42
The role of C/EBPbeta in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia (2003) 1.38
ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets. Dev Biol (2003) 1.37
Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol (2002) 1.37
A beta-catenin survival signal is required for normal lobular development in the mammary gland. J Cell Sci (2003) 1.34
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol (2013) 1.30
Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium. Mol Endocrinol (2002) 1.30
Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Genomics (2003) 1.29
Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome. Physiol Genomics (2008) 1.28
cis-requirement for the maintenance of round spermatid-specific transcription. Dev Biol (2006) 1.28
Phosphorylation of the linker histone H1 by CDK regulates its binding to HP1alpha. Mol Cell (2006) 1.24
Modern technology calls for a modern approach to classification of epileptic seizures and the epilepsies. Epilepsia (2012) 1.24
p190-B RhoGAP regulates mammary ductal morphogenesis. Mol Endocrinol (2003) 1.23
The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis. Proc Natl Acad Sci U S A (2009) 1.22
Applying signal-detection theory to the study of observer accuracy and bias in behavioral assessment. J Appl Behav Anal (2010) 1.22
Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia (2005) 1.22
Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Mol Endocrinol (2007) 1.19
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res (2003) 1.18
Tracking of multimodal therapeutic nanocomplexes targeting breast cancer in vivo. Nano Lett (2010) 1.18
Rhox homeobox gene cluster: recent duplication of three family members. Genesis (2006) 1.17
Hormone dependence in premalignant mammary progression. Cancer Res (2003) 1.16
Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res (2013) 1.16
Computational and transcriptional evidence for microRNAs in the honey bee genome. Genome Biol (2007) 1.15
The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. RNA Biol (2010) 1.15
Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Res (2009) 1.15
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep (2013) 1.13
Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Mol Endocrinol (2006) 1.13
Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cells. FASEB J (2006) 1.11
P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Mol Endocrinol (2006) 1.11
Keratin 6 is not essential for mammary gland development. Breast Cancer Res (2006) 1.10
A critical role for the inflammatory response in a mouse model of preneoplastic progression. Cancer Res (2006) 1.09
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A (2010) 1.09
CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells (2010) 1.08
Wnt and mammary stem cells: hormones cannot fly wingless. Curr Opin Pharmacol (2010) 1.08
Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res (2010) 1.07
Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage. Breast Cancer Res (2007) 1.06
An inducible system for the study of FGF signalling in early amphibian development. Dev Biol (2003) 1.05
Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol (2007) 1.04
Low-frequency electrical stimulation of a fiber tract in temporal lobe epilepsy. Ann Neurol (2013) 1.03
Transcriptional profiling of mammary gland side population cells. Stem Cells (2005) 1.02
The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia (2010) 1.02
Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. J Biol Chem (2009) 1.01
Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b. J Biol Chem (2003) 1.01
Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol Cell Biol (2011) 1.00
STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells (2014) 0.99
P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Res (2010) 0.98
Mammary gland macrophages: pleiotropic functions in mammary development. J Mammary Gland Biol Neoplasia (2006) 0.97
Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function. Stem Cells (2013) 0.97
Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol (2006) 0.97
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol (2011) 0.96
Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem (2005) 0.96
Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One (2012) 0.95
Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res (2003) 0.95
Chk1 versus Cdc25: chking one's levels of cellular proliferation. Cell Cycle (2004) 0.95
Small players with big roles: microRNAs as targets to inhibit breast cancer progression. Curr Drug Targets (2010) 0.93
The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development. Mol Endocrinol (2002) 0.93
Spermatid-specific promoter of the SP-10 gene functions as an insulator in somatic cells. Dev Biol (2003) 0.93
Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice. Age (Dordr) (2012) 0.93
Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Breast Cancer Res (2009) 0.93
Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Breast Cancer Res (2014) 0.92