Published in J Virol on April 01, 1992
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol Cell Biol (1994) 2.71
Constitutive expression of an ISGF2/IRF1 transgene leads to interferon-independent activation of interferon-inducible genes and resistance to virus infection. J Virol (1992) 1.77
Vaccinia virus E3 protein prevents the antiviral action of ISG15. PLoS Pathog (2008) 1.57
Differential regulation of miR-21 and miR-146a by Epstein-Barr virus-encoded EBNA2. Leukemia (2012) 1.02
Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 replication and transcription activator regulates viral and cellular genes via interferon-stimulated response elements. J Virol (2005) 1.02
Interferon-β signaling contributes to Ras transformation. PLoS One (2011) 0.89
Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases. J Clin Invest (2001) 0.86
ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system. Oncotarget (2016) 0.78
Oncogenicity of human papillomavirus- or adenovirus-transformed cells correlates with resistance to lysis by natural killer cells. J Virol (1995) 0.78
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell (1988) 9.04
The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element. Cell (1983) 8.19
Complex splicing patterns of RNAs from the early regions of adenovirus-2. J Mol Biol (1979) 7.53
Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses. Nature (1979) 6.60
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev (1988) 6.08
Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells. Nature (1983) 5.40
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09
Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61
Interferon response element of the human gene 6-16. EMBO J (1988) 4.11
Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes. Mol Cell Biol (1986) 3.52
Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem (1987) 3.41
Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products. Proc Natl Acad Sci U S A (1984) 2.39
Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways. Proc Natl Acad Sci U S A (1989) 2.38
Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF). Proc Natl Acad Sci U S A (1982) 2.36
Adenovirus E1A protein paradigm viral transactivator. Annu Rev Genet (1989) 2.23
A novel function of the transforming domain of E1a: repression of AP-1 activity. Cell (1990) 1.97
Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products. J Virol (1988) 1.88
Increased MHC H-2K gene transcription in cultured mouse embryo cells after adenovirus infection. Nature (1985) 1.41
Modulation of the tumorigenicity of human adenovirus-12-transformed cells by interferon. Cell (1985) 1.41
Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression. J Virol (1985) 1.38
Tumor necrosis factor acts synergistically with autocrine interferon-beta and increases interferon-beta mRNA levels in human fibroblasts. J Biol Chem (1989) 1.37
Postinduction repression of the beta-interferon gene is mediated through two positive regulatory domains. Proc Natl Acad Sci U S A (1990) 1.37
Cold-sensitive expression of transformation by a host range mutant of type 5 adenovirus. Proc Natl Acad Sci U S A (1983) 1.29
The cellular transcription factor E2f requires viral E1A and E4 gene products for increased DNA-binding activity and functions to stimulate adenovirus E2A gene expression. J Virol (1989) 1.13
Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a. Mol Cell Biol (1990) 1.11
Changes in NF-kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta-IFN gene expression in Ad5- versus Ad12-transformed cells. EMBO J (1991) 1.08
E1a revisited: the case for multiple cooperative trans-activation domains. New Biol (1991) 1.03
Tandemly repeated hexamer sequences within the beta interferon promoter can function as an inducible regulatory element in activation by the adenovirus E1B 19-kilodalton protein. J Virol (1990) 0.99
Changes of chromatin conformation around mouse interferon-beta gene associated with induction of interferon synthesis. Nucleic Acids Res (1985) 0.99
Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells. Science (1985) 0.95
Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells. Proc Natl Acad Sci U S A (1986) 0.94
The efficiency of adenovirus transformation of rodent cells is inversely related to the rate of viral E1A gene expression. J Virol (1990) 0.93
Growth regulation of melanoma cells by interferon and (2'-5')oligoadenylate synthetase. Mol Cell Biol (1983) 0.92
The state of cellular differentiation determines the activity of the adenovirus E1A enhancer element: evidence for negative regulation of enhancer function. J Virol (1990) 0.89
trans activation of type 1 interferon promoters by simian virus 40 T antigen. Mol Cell Biol (1988) 0.89
Interferons: a new class of tumor suppressor genes? Cancer Cells (1990) 0.83
The expression of heat shock protein hsp27 and a complexed 22-kilodalton protein is inversely correlated with oncogenicity of adenovirus-transformed cells. J Virol (1989) 0.83
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev (1988) 6.08
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science (1995) 3.10
Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol Cell Biol (1985) 3.04
Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region. Proc Natl Acad Sci U S A (1986) 2.92
Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis. J Virol (1984) 2.82
Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products. Proc Natl Acad Sci U S A (1984) 2.39
Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF). Proc Natl Acad Sci U S A (1982) 2.36
Endothelial interferon regulatory factor 1 cooperates with NF-kappa B as a transcriptional activator of vascular cell adhesion molecule 1. Mol Cell Biol (1995) 2.12
Activation of the p38 mitogen-activated protein kinase by type I interferons. J Biol Chem (1999) 1.94
Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products. J Virol (1988) 1.88
Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression. Mol Cell Biol (1986) 1.73
Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J Immunol (1996) 1.68
Strand-invasion of duplex DNA by peptide nucleic acid oligomers. Proc Natl Acad Sci U S A (1993) 1.63
Cells resistant to interferon are defective in activation of a promoter-binding factor. EMBO J (1988) 1.60
Expression and function of the leucine zipper protein Par-4 in apoptosis. Mol Cell Biol (1997) 1.59
Positive and negative regulatory elements in the mouse albumin enhancer. Proc Natl Acad Sci U S A (1989) 1.58
Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading. Proc Natl Acad Sci U S A (1987) 1.57
Fluoroquinolone action against clinical isolates of Mycobacterium tuberculosis: effects of a C-8 methoxyl group on survival in liquid media and in human macrophages. Antimicrob Agents Chemother (1999) 1.56
Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas. Oncogene (1997) 1.50
Indications, outcomes, and provider volumes for carotid endarterectomy. JAMA (1998) 1.48
STF-IL-4: a novel IL-4-induced signal transducing factor. EMBO J (1994) 1.46
Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma. Cancer Res (1998) 1.39
Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells. J Virol (1983) 1.39
Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts. Int J Cancer (1993) 1.35
Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. Immunity (1996) 1.35
Cold-sensitive expression of transformation by a host range mutant of type 5 adenovirus. Proc Natl Acad Sci U S A (1983) 1.29
A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells. Cancer Res (1993) 1.26
Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned rat embryo fibroblasts. Int J Cancer (1995) 1.22
Reovirus serotypes 1 and 3 differ in their in vitro association with microtubules. J Virol (1979) 1.15
Effect on transformation of mutations in the early region 1b-encoded 21- and 55-kilodalton proteins of adenovirus 5. J Virol (1984) 1.15
Nitroglycerin to unmask reversible asynergy. Correlation with post coronary bypass ventriculography. Circulation (1974) 1.14
Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells. Blood (1996) 1.13
The mouse albumin enhancer contains a negative regulatory element that interacts with a novel DNA-binding protein. Mol Cell Biol (1990) 1.12
Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation. J Virol (1984) 1.10
Transcriptional regulation of the albumin gene in cultured rat hepatocytes. Role of basement-membrane matrix. Mol Biol Med (1990) 1.08
Involvement of two regulatory elements in interferon-gamma-regulated expression of human indoleamine 2,3-dioxygenase gene. J Interferon Cytokine Res (1995) 1.08
Changes in NF-kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta-IFN gene expression in Ad5- versus Ad12-transformed cells. EMBO J (1991) 1.08
Pyrrol[1,4]benzodiazepine antibiotics. Proposed structures and characteristics of the in vitro deoxyribonucleic acid adducts of anthramycin, tomaymycin, sibiromycin, and neothramycins A and B. Biochemistry (1981) 1.07
Interferon-gamma potentiates the antiviral activity and the expression of interferon-stimulated genes induced by interferon-alpha in U937 cells. J Interferon Res (1992) 1.07
Transformation of human skeletal muscle cells by simian virus 40. Proc Natl Acad Sci U S A (1983) 1.05
Distinct activation of murine interferon-alpha promoter region by IRF-1/ISFG-2 and virus infection. Nucleic Acids Res (1992) 1.05
Cadmium-induced accumulation of metallothionein messenger RNA in rat liver. J Biol Chem (1981) 1.05
The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity. J Med Chem (2000) 1.04
Mutations in the adenovirus major late promoter: effects on viability and transcription during infection. Mol Cell Biol (1987) 1.03
The upstream factor-binding site is not essential for activation of transcription from the adenovirus major late promoter. J Virol (1990) 1.03
Susceptibility of Adenovirus 2-transformed rat cell lines to natural killer (NK) cells: direct correlation between NK resistance and in vivo tumorigenesis. J Immunol (1984) 1.01
The interferon-stimulable response elements of two human genes detect overlapping sets of transcription factors. Eur J Biochem (1993) 1.01
DNase I-hypersensitive sites in the 5'-flanking region of the rat serum albumin gene: correlation between chromatin structure and transcriptional activity. Proc Natl Acad Sci U S A (1986) 1.00
Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters. Mol Cell Biol (1986) 0.99
The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression. J Biol Chem (1996) 0.98
Differential regulation of hepatocyte-enriched transcription factors explains changes in albumin and transthyretin gene expression among hepatoma cells. New Biol (1991) 0.98
Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes. Proc Natl Acad Sci U S A (1995) 0.98
Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E. Biochem Biophys Res Commun (1997) 0.96
DNA template effect on RNA splicing: two copies of the same gene in the same nucleus are processed differently. EMBO J (1991) 0.96
Repression of adenovirus E1A enhancer activity by a novel zinc finger-containing DNA-binding protein related to the GLI-Kruppel protein. EMBO J (1993) 0.96
The involvement of a stress-activated pathway in equine influenza virus-mediated apoptosis. Virology (2001) 0.95
Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells. Science (1985) 0.95
Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities. J Med Chem (1999) 0.95
Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells. Proc Natl Acad Sci U S A (1986) 0.94
Proteasome- and p53-dependent masking of signal transducer and activator of transcription (STAT) factors. J Biol Chem (1997) 0.94
DNA-dependent RNA polymerase from Pseudomonas BAL-31. II. Transcription of the allomorphic forms of bacteriophage PM2 DNA. Biochemistry (1975) 0.93
The efficiency of adenovirus transformation of rodent cells is inversely related to the rate of viral E1A gene expression. J Virol (1990) 0.93
Transfer of a dominant-acting tumor-inducing oncogene from human prostatic carcinoma cells to cloned rat embryo fibroblast cells by DNA-transfection. Anticancer Res (1992) 0.93
Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor. J Biol Chem (1994) 0.92
An improved method to obtain a large number of mutants in a defined region of DNA. Methods Enzymol (1987) 0.92
The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity. J Control Release (2001) 0.92
Transcriptional regulation of interferon-stimulated genes: a DNA response element and induced proteins that recognize it. Cold Spring Harb Symp Quant Biol (1988) 0.91
Opposing effects of interferon produced in bacteria and of tumor promoters on myogenesis in human myoblast cultures. Proc Natl Acad Sci U S A (1983) 0.90
The state of cellular differentiation determines the activity of the adenovirus E1A enhancer element: evidence for negative regulation of enhancer function. J Virol (1990) 0.89
Kinase-deficient forms of Jak1 and Tyk2 inhibit interferon alpha signaling in a dominant manner. Eur J Biochem (1997) 0.89
Hepatoma variants (C2) are defective for transcriptional and post-transcriptional actions from both endogenous and viral genomes. EMBO J (1987) 0.88
Cardiac Whipple disease: identification of Whipple bacillus by electron microscopy of a patient before death. Ann Intern Med (1997) 0.88
Definition of the interferon-alpha receptor-binding domain on the TYK2 kinase. J Biol Chem (1998) 0.88
Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. Thyroid (2001) 0.88
Measurement of the effect of interferons on cellular differentiation of human skeletal muscle cells. Methods Enzymol (1986) 0.87
Inhibition of collagenolytic activity relates to quantitative reduction of invasion in vitro in a c-Ha-ras transfected glial cell line. J Neurooncol (1994) 0.87
Evidence that USF can interact with only a single general transcription complex at one time. Mol Cell Biol (1992) 0.87
DNA-dependent RNA polymerase from Pseudomonas BAL-31. I. Purification and properties of the enzyme. Biochemistry (1975) 0.86
Mechanisms of cisplatin (cis-diamminodichloroplatinum II)-induced cytotoxicity and genotoxicity in yeast. Mutat Res (1984) 0.86
Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate. Mol Cell Biol (1984) 0.85
Cytokine regulation of the liver transcription factor hepatocyte nuclear factor-3 beta is mediated by the C/EBP family and interferon regulatory factor 1. Cell Growth Differ (1995) 0.84
Induction and progression of the transformed phenotype in cloned rat embryo fibroblast cells: studies employing type 5 adenovirus and wild-type and mutant Ha-ras oncogenes. Mol Carcinog (1992) 0.84
Synthesis of complementary viral transcripts early in productive infection with adenovirus 2. Virology (1976) 0.83
Size distribution of polyadenylated adenovirus 2 RNA synthesized in isolated nuclei. Biochemistry (1978) 0.83
A thermolabile mutant of adenovirus 5 resulting from a substitution mutation in the protein VIII gene. J Virol (1985) 0.83
Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay. Proc Natl Acad Sci U S A (1995) 0.82
Exercise-related ventricular premature complexes in coronary heart disease. Correlations with ischemia and angiographic severity. Ann Intern Med (1974) 0.82
Use of bicycle ergometry and sustained handgrip exercise in the diagnosis of presence and extent of coronary heart disease. Br Heart J (1973) 0.82
Misregulated expression of the cyclin dependent kinase 2 protein in human fibroblasts is accompanied by the inability to maintain a G2 arrest following DNA damage. Cell Growth Differ (1995) 0.82
Susceptibility to virus infection is determined by a Stat-mediated response to the autocrine effect of virus-induced type I interferon. Cytokine (1997) 0.82
Role of metallothionein in detoxification and tolerance to transition metals. Experientia Suppl (1987) 0.82
Quantitative and qualitative differences in growth, invasion and lung colonization of an anaplastic and a papillary human thyroid cancer cell line in vitro and in vivo. Clin Exp Metastasis (1996) 0.80
Suppression of the progression phenotype in somatic cell hybrids occurs in the absence of altered adenovirus type 5 gene expression. Mol Cell Biol (1990) 0.80