Published in J Virol on November 01, 1985
Expression of human class II major histocompatibility complex antigens using retrovirus vectors. Proc Natl Acad Sci U S A (1987) 4.84
Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products. Mol Cell Biol (1987) 2.38
Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature. Mol Cell Biol (1989) 2.04
Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J (1988) 1.80
Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus. Proc Natl Acad Sci U S A (1991) 1.63
Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteins. EMBO J (1987) 1.61
Expression of adenovirus E1B mutant phenotypes is dependent on the host cell and on synthesis of E1A proteins. J Virol (1987) 1.35
The amino-terminal region of the adenovirus serotype 5 E1a protein performs two separate functions when expressed in primary baby rat kidney cells. Mol Cell Biol (1988) 1.34
Regulation of early adenovirus gene expression. Microbiol Rev (1987) 1.34
Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment. J Cell Biol (1989) 1.32
Activation of adenovirus 5 E1A transcription by region E1B in transformed primary rat cells. EMBO J (1987) 1.17
A retrovirus expressing the 12S adenoviral E1A gene product can immortalize epithelial cells from a broad range of rat tissues. Mol Cell Biol (1988) 1.13
Induction of sensitivity to the cytotoxic action of tumor necrosis factor alpha by adenovirus E1A is independent of transformation and transcriptional activation. J Virol (1990) 1.04
Simian virus 40 large tumor antigen alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification. Proc Natl Acad Sci U S A (1992) 1.03
Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts. J Virol (1992) 0.94
Use of recombinant retroviruses to study the regulation of integrated adenovirus early promoters. J Virol (1988) 0.92
Adenovirus E1A-mediated negative control of genes activated during F9 differentiation. Mol Cell Biol (1989) 0.91
Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene. Proc Natl Acad Sci U S A (1989) 0.90
Induction of cell cycle progression by adenovirus E1A gene 13S- and 12S-mRNA products in quiescent rat cells. Mol Cell Biol (1987) 0.84
Induction of different morphologic features of malignant melanoma and pigmented lesions after transformation of murine melanocytes with bFGF-cDNA and H-ras, myc, neu, and E1a oncogenes. Am J Pathol (1991) 0.84
Differential requirement for adenovirus type 12 E1A gene products in oncogenic transformation. J Virol (1990) 0.82
Characterization of the 55-residue protein encoded by the 9S E1A mRNA of species C adenovirus. J Virol (2012) 0.79
A novel general approach to eucaryotic mutagenesis functionally identifies conserved regions within the adenovirus 13S E1A polypeptide. Mol Cell Biol (1986) 0.78
Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation. BMC Genomics (2009) 0.78
Comparison of the Life Cycles of Genetically Distant Species C and Species D Human Adenoviruses Ad6 and Ad26 in Human Cells. J Virol (2015) 0.77
E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription. J Virol (1991) 0.77
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
Preparative and analytical purification of DNA from agarose. Proc Natl Acad Sci U S A (1979) 27.20
Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell (1983) 25.46
Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell (1984) 13.91
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature (1983) 11.61
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40. Cold Spring Harb Symp Quant Biol (1975) 7.76
Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell (1983) 7.22
Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell (1982) 6.78
Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA. Virology (1980) 5.86
Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature (1982) 5.61
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
Complete transformation by adenovirus 2 requires both E1A proteins. Cell (1984) 3.80
Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus. Cell (1981) 3.80
Defective transforming capacity of adenovirus type 5 host-range mutants. Virology (1978) 3.52
HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism. Mol Cell Biol (1984) 3.44
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection. Proc Natl Acad Sci U S A (1984) 3.24
Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level. Proc Natl Acad Sci U S A (1984) 2.64
Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species. J Virol (1981) 2.57
The TATA homology and the mRNA 5' untranslated sequence are not required for expression of essential adenovirus E1A functions. Cell (1982) 2.46
Adenovirus-induced alterations of the cell growth cycle: a requirement for expression of E1A but not of E1B. J Virol (1983) 1.93
Splicing of adenovirus 2 early region 1A mRNAs is non-sequential. J Mol Biol (1983) 1.82
Comparison of nucleotide sequences of the early E1a regions for subgroups A, B and C of human adenoviruses. Gene (1980) 1.68
The relationship between region E1a and E1b of human adenoviruses in cell transformation. Gene (1982) 1.50
The molecular structure of the 9S mRNA from early region 1A of adenovirus serotype 2. J Mol Biol (1983) 1.46
Incomplete transformation of rat cells by a small fragment of adenovirus 12 DNA. Virology (1979) 1.37
Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell (1983) 25.46
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proc Natl Acad Sci U S A (1981) 22.21
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med (1996) 17.51
Efficient translation of tobacco mosaic virus RNA and rabbit globin 9S RNA in a cell-free system from commercial wheat germ. Proc Natl Acad Sci U S A (1973) 16.94
Expression of a bacterial gene in mammalian cells. Science (1980) 15.46
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell (1991) 14.23
Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell (1984) 13.91
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A (1993) 11.95
Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome. Nature (1979) 9.99
Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation. Proc Natl Acad Sci U S A (1979) 9.94
Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc Natl Acad Sci U S A (1988) 9.35
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci U S A (1996) 8.53
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev (1996) 7.78
Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature (1999) 7.73
Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc Natl Acad Sci U S A (1977) 7.46
PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science (1996) 6.33
Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell (1983) 6.27
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med (1997) 6.13
Developmental potential and dynamic behavior of hematopoietic stem cells. Cell (1986) 5.98
High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. Proc Natl Acad Sci U S A (1984) 5.89
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (1991) 5.82
A common progenitor for neurons and glia persists in rat retina late in development. Nature (1987) 5.54
Vertebrate neural cell-fate determination: lessons from the retina. Nat Rev Neurosci (2001) 5.26
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature (1984) 5.10
Simian virus 40 DNA directs synthesis of authentic viral polypeptides in a linked transcription-translation cell-free system. Proc Natl Acad Sci U S A (1975) 4.98
Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell (1997) 4.88
Expression of human class II major histocompatibility complex antigens using retrovirus vectors. Proc Natl Acad Sci U S A (1987) 4.84
Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev (1994) 4.58
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
Physiological consequences of loss of plasminogen activator gene function in mice. Nature (1994) 4.40
Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells. Cell (1986) 4.32
Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes Dev (1990) 4.17
Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell (1992) 3.82
A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev (1997) 3.80
Retinopathy and attenuated circadian entrainment in Crx-deficient mice. Nat Genet (1999) 3.42
Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell (1997) 3.42
Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity (1995) 3.37
Pre-proparathyroid hormone: a direct translation product of parathyroid messenger RNA. Proc Natl Acad Sci U S A (1974) 3.24
Two dominant-acting selectable markers for gene transfer studies in mammalian cells. Proc Natl Acad Sci U S A (1988) 3.21
A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proc Natl Acad Sci U S A (1992) 3.21
Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell (2001) 3.20
Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1. EMBO J (1999) 3.18
Lineage-specific expression of a human beta-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells. Nature (1988) 3.18
Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA. J Mol Biol (1981) 3.18
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr Biol (2005) 3.15
Cell-free translation of messenger RNA of simian virus 40: synthesis of the major capsid protein. Proc Natl Acad Sci U S A (1974) 3.04
A chicken-yeast chimeric beta-tubulin protein is incorporated into mouse microtubules in vivo. Cell (1986) 3.00
Crystal structure of a beta-catenin/Tcf complex. Cell (2000) 2.93
Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest (2000) 2.92
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nat Cell Biol (2001) 2.91
Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis. Nat Genet (2000) 2.85
The genetic program of hematopoietic stem cells. Science (2000) 2.85
Cellular and developmental properties of fetal hematopoietic stem cells. Cell (1990) 2.83
Lineage-independent determination of cell type in the embryonic mouse retina. Neuron (1990) 2.83
Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites. Nature (1998) 2.82
Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc Natl Acad Sci U S A (2001) 2.81
Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Mol Cell Biol (1986) 2.81
Widespread dispersion of neuronal clones across functional regions of the cerebral cortex. Science (1992) 2.79
Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector. Mol Cell Biol (1987) 2.77
Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. J Neurosci (2000) 2.70
In vitro maintenance of highly purified, transplantable hematopoietic stem cells. Blood (1997) 2.70
Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo. Proc Natl Acad Sci U S A (1986) 2.69
Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc Natl Acad Sci U S A (1995) 2.68
Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. Proc Natl Acad Sci U S A (1993) 2.65
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci U S A (1991) 2.60
Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. N Engl J Med (1987) 2.59
E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related. J Virol (1985) 2.59
rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells. Neuron (2000) 2.56
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. Development (1999) 2.56
Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo. J Virol (1988) 2.55
Negative regulation of human c-fos expression by the retinoblastoma gene product. Nature (1990) 2.50
Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J Clin Invest (1996) 2.49
NeuroD regulates multiple functions in the developing neural retina in rodent. Development (1999) 2.49
Arrangement of late RNAs transcribed from a 7.1-kilobase EcoRI vaccinia virus DNA fragment. J Virol (1984) 2.48
Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. Proc Natl Acad Sci U S A (1988) 2.44
Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. J Cell Biol (1997) 2.42
Control of Müller glial cell proliferation and activation following retinal injury. Nat Neurosci (2000) 2.37
Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx. Curr Biol (2000) 2.36
rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc Natl Acad Sci U S A (1997) 2.29
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci U S A (1998) 2.29
Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science (1989) 2.28
A homeobox gene essential for zebrafish notochord development. Nature (1995) 2.25
A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell (1991) 2.23
The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle. Cell (1987) 2.22
Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest (1993) 2.20
The expression and function of Notch pathway genes in the developing rat eye. J Neurosci (1997) 2.19
Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3. Development (1995) 2.18
Direct biochemical mapping of eukaryotic viral DNA by means of a linked transcription-translation cell-free system. Proc Natl Acad Sci U S A (1976) 2.17