PubRank

David E Hill

Author PubWeight™ 229.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Towards a proteome-scale map of the human protein-protein interaction network. Nature 2005 24.76
2 A map of the interactome network of the metazoan C. elegans. Science 2004 15.60
3 COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 2010 14.62
4 A mitochondrial protein compendium elucidates complex I disease biology. Cell 2008 13.51
5 High-quality binary protein interaction map of the yeast interactome network. Science 2008 10.65
6 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 2006 8.61
7 Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 2007 7.60
8 C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nat Genet 2003 7.25
9 An empirical framework for binary interactome mapping. Nat Methods 2008 6.59
10 Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 2004 5.81
11 An experimentally derived confidence score for binary protein-protein interactions. Nat Methods 2008 5.27
12 A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. Cell 2009 4.98
13 A public genome-scale lentiviral expression library of human ORFs. Nat Methods 2011 4.98
14 Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet 2007 4.69
15 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics 2007 4.62
16 SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature 2011 4.57
17 Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature 2012 4.35
18 Literature-curated protein interaction datasets. Nat Methods 2009 4.21
19 Edgetic perturbation models of human inherited disorders. Mol Syst Biol 2009 3.96
20 Combined functional genomic maps of the C. elegans DNA damage response. Science 2002 3.74
21 Independently evolved virulence effectors converge onto hubs in a plant immune system network. Science 2011 3.72
22 Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature 2008 3.68
23 Systematic analysis of genes required for synapse structure and function. Nature 2005 3.67
24 Epstein-Barr virus and virus human protein interaction maps. Proc Natl Acad Sci U S A 2007 3.50
25 Human ORFeome version 1.1: a platform for reverse proteomics. Genome Res 2004 3.36
26 A first version of the Caenorhabditis elegans Promoterome. Genome Res 2004 3.29
27 Interactome: gateway into systems biology. Hum Mol Genet 2005 3.00
28 Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Nat Methods 2009 2.50
29 A protein domain-based interactome network for C. elegans early embryogenesis. Cell 2008 2.23
30 Next-generation sequencing to generate interactome datasets. Nat Methods 2011 2.06
31 Protein interactome reveals converging molecular pathways among autism disorders. Sci Transl Med 2011 2.04
32 Isoform discovery by targeted cloning, 'deep-well' pooling and parallel sequencing. Nat Methods 2008 2.03
33 High-quality binary interactome mapping. Methods Enzymol 2010 1.94
34 C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions. Genome Res 2004 1.92
35 Generation of the Brucella melitensis ORFeome version 1.1. Genome Res 2004 1.86
36 'Edgetic' perturbation of a C. elegans BCL2 ortholog. Nat Methods 2009 1.74
37 Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab 2008 1.65
38 Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol 2012 1.54
39 BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Curr Biol 2004 1.52
40 ORFeome projects: gateway between genomics and omics. Curr Opin Chem Biol 2004 1.40
41 High-throughput expression of C. elegans proteins. Genome Res 2004 1.32
42 Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. Cell Microbiol 2011 1.22
43 Shifted Transversal Design smart-pooling for high coverage interactome mapping. Genome Res 2009 1.22
44 Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Mol Cell 2013 1.21
45 From genome to proteome: developing expression clone resources for the human genome. Hum Mol Genet 2006 1.21
46 Metabolic network analysis integrated with transcript verification for sequenced genomes. Nat Methods 2009 1.21
47 Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. Retrovirology 2012 1.16
48 Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Hum Mol Genet 2010 1.16
49 Yeast one-hybrid assays for gene-centered human gene regulatory network mapping. Nat Methods 2011 1.12
50 Mycobacterium tuberculosis type VII secreted effector EsxH targets host ESCRT to impair trafficking. PLoS Pathog 2013 1.10
51 New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones. Genome Res 2005 1.07
52 Revisiting the Saccharomyces cerevisiae predicted ORFeome. Genome Res 2008 1.07
53 Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans. Genetics 2011 1.02
54 A genome-wide gene function prediction resource for Drosophila melanogaster. PLoS One 2010 1.00
55 Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog 2012 0.95
56 SH3 interactome conserves general function over specific form. Mol Syst Biol 2013 0.94
57 Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase. Methods 2012 0.93
58 Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome. Genome Res 2009 0.93
59 Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Mol Cell Proteomics 2010 0.92
60 C. elegans network biology: a beginning. WormBook 2006 0.91
61 Systematic identification of pathological lamin A interactors. Mol Biol Cell 2014 0.86
62 Protein-protein interactions and networks: forward and reverse edgetics. Methods Mol Biol 2011 0.85
63 Biochemical clustering of monomeric GTPases of the Ras superfamily. Mol Cell Proteomics 2005 0.82
64 CKIP-1 regulates mammalian and zebrafish myoblast fusion. J Cell Sci 2012 0.81
65 An RS motif within the Epstein-Barr virus BLRF2 tegument protein is phosphorylated by SRPK2 and is important for viral replication. PLoS One 2013 0.79
66 Pooled ORF expression technology (POET): using proteomics to screen pools of open reading frames for protein expression. Mol Cell Proteomics 2005 0.79
67 Proteome expression moves in vitro: resources and tools for harnessing the human proteome. Nat Methods 2008 0.77
68 Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits. Am J Hum Genet 2017 0.75
69 Dynamic Ligand Exchange as a Mechanistic Probe in Pd-Catalyzed Enantioselective C-H Functionalization Reactions Using Monoprotected Amino Acid Ligands. J Am Chem Soc 2017 0.75