Published in Nature on October 21, 2004
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
Genome assembly forensics: finding the elusive mis-assembly. Genome Biol (2008) 4.91
MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A (2008) 4.33
Genome-wide identification of human functional DNA using a neutral indel model. PLoS Comput Biol (2006) 3.16
Between a chicken and a grape: estimating the number of human genes. Genome Biol (2010) 1.72
Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancer. Int J Biol Sci (2013) 1.62
NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression. MBio (2013) 1.55
Long non-coding RNA in cancer. Int J Mol Sci (2013) 1.52
Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity. Nucleic Acids Res (2013) 1.44
Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis. Gut (2013) 1.37
Novel classes of non-coding RNAs and cancer. J Transl Med (2012) 1.35
Discovery of nuclear-encoded genes for the neurotoxin saxitoxin in dinoflagellates. PLoS One (2011) 1.34
Hundreds of putatively functional small open reading frames in Drosophila. Genome Biol (2011) 1.26
The ubiquitin-proteasome pathway and synaptic plasticity. Learn Mem (2010) 1.20
A meta-analysis of the genomic and transcriptomic composition of complex life. Cell Cycle (2013) 1.16
Molecular mechanisms of traumatic brain injury: the missing link in management. World J Emerg Surg (2009) 1.15
Small nucleolar RNAs in cancer. Biochim Biophys Acta (2012) 1.11
Non-coding RNAs as regulators of mammary development and breast cancer. J Mammary Gland Biol Neoplasia (2012) 1.11
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases. Circ Res (2013) 1.01
Long non-coding RNAs (lncRNAs) and viral infections. Biomed Pharmacother (2013) 0.98
Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks. PLoS Comput Biol (2010) 0.98
The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted Transcripts. Curr Genomics (2007) 0.97
Glycobiology on the fly: developmental and mechanistic insights from Drosophila. Glycobiology (2008) 0.96
Human gene expression sensitivity according to large scale meta-analysis. BMC Bioinformatics (2009) 0.95
Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. Biochem Pharmacol (2013) 0.95
Knowledge gaining by human genetic studies on tuberculosis susceptibility. J Hum Genet (2010) 0.94
Pharmacogenetics of drug metabolizing enzymes and transporters: effects on pharmacokinetics and pharmacodynamics of anticancer agents. Anticancer Agents Med Chem (2010) 0.88
Genetics and proteomics: deciphering gene association studies in critical illness. Crit Care (2006) 0.87
The roles of microRNAs on tuberculosis infection: meaning or myth? Tuberculosis (Edinb) (2013) 0.86
Expression of the microRNAs hsa-miR-15a and hsa-miR-16-1 in lens epithelial cells of patients with age-related cataract. Int J Clin Exp Med (2015) 0.84
Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1 day meeting on genetic manipulation of cells). Cell Biol Toxicol (2009) 0.84
Proteomics and mass spectrometry for cancer biomarker discovery. Biomark Insights (2007) 0.84
Non-coding RNAs in lung cancer. Oncoscience (2014) 0.83
In Silico screening for functional candidates amongst hypothetical proteins. BMC Bioinformatics (2009) 0.83
Splicing and alternative splicing in rice and humans. BMB Rep (2013) 0.83
Long Noncoding RNA in Digestive Tract Cancers: Function, Mechanism, and Potential Biomarker. Oncologist (2015) 0.82
Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses. RNA (2013) 0.82
The road from next-generation sequencing to personalized medicine. Per Med (2015) 0.81
LncRNA uc.48+ is involved in diabetic neuropathic pain mediated by the P2X3 receptor in the dorsal root ganglia. Purinergic Signal (2015) 0.80
Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices. Chem Commun (Camb) (2013) 0.79
Comprehensive analysis of long non-coding RNA expression profiles in hepatitis B virus-related hepatocellular carcinoma. Oncotarget (2016) 0.79
Statistical significance in genetic association studies. Clin Invest Med (2010) 0.78
Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications. World J Gastroenterol (2016) 0.77
Genomics and proteomics in stem cell research: the road ahead. Anat Cell Biol (2010) 0.77
Attractor metabolic networks. PLoS One (2013) 0.77
LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer. Oncotarget (2015) 0.77
RGST - Rat Gene Symbol Tracker, a database for defining official rat gene symbols. BMC Genomics (2008) 0.76
Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer. Oncotarget (2015) 0.76
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep (2017) 0.75
Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease. Diabetologia (2016) 0.75
Design of high-performance parallelized gene predictors in MATLAB. BMC Res Notes (2012) 0.75
Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature. Oncotarget (2016) 0.75
Identification of Long Non-Coding RNAs Deregulated in Multiple Myeloma Cells Resistant to Proteasome Inhibitors. Genes (Basel) (2016) 0.75
LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy. Cell Death Dis (2017) 0.75
Chemo brain: From discerning mechanisms to lifting the brain fog - An aging connection. Cell Cycle (2017) 0.75
LncRNA NONRATT021972 Was Associated with Neuropathic Pain Scoring in Patients with Type 2 Diabetes. Behav Neurol (2017) 0.75
Finishing the euchromatic sequence of the human genome. Nature (2004) 41.40
Shotgun sequence assembly and recent segmental duplications within the human genome. Nature (2004) 7.91
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The Bioperl toolkit: Perl modules for the life sciences. Genome Res (2002) 58.63
International network of cancer genome projects. Nature (2010) 20.35
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature (2012) 8.31
WormBase: better software, richer content. Nucleic Acids Res (2006) 6.78
JBrowse: a next-generation genome browser. Genome Res (2009) 6.77
The International HapMap Project Web site. Genome Res (2005) 5.96
WormBase: a cross-species database for comparative genomics. Nucleic Acids Res (2003) 5.28
WormBase: a comprehensive resource for nematode research. Nucleic Acids Res (2009) 5.20
WormBase: a multi-species resource for nematode biology and genomics. Nucleic Acids Res (2004) 4.14
WormBase: new content and better access. Nucleic Acids Res (2006) 4.01
WormBase: a comprehensive data resource for Caenorhabditis biology and genomics. Nucleic Acids Res (2005) 3.82
WormBase 2007. Nucleic Acids Res (2007) 3.69
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Gramene, a tool for grass genomics. Plant Physiol (2002) 3.14
Arabidopsis reactome: a foundation knowledgebase for plant systems biology. Plant Cell (2008) 2.50
modMine: flexible access to modENCODE data. Nucleic Acids Res (2011) 2.18
The SNP Consortium website: past, present and future. Nucleic Acids Res (2003) 2.08
The plant structure ontology, a unified vocabulary of anatomy and morphology of a flowering plant. Plant Physiol (2006) 2.03
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
WormBook: the online review of Caenorhabditis elegans biology. Nucleic Acids Res (2006) 1.71
The Reactome BioMart. Database (Oxford) (2011) 1.66
Computational approaches to identify functional genetic variants in cancer genomes. Nat Methods (2013) 1.64
Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans. Genome Res (2006) 1.56
nGASP--the nematode genome annotation assessment project. BMC Bioinformatics (2008) 1.52
Feasibility of real time next generation sequencing of cancer genes linked to drug response: results from a clinical trial. Int J Cancer (2012) 1.49
WormBase as an integrated platform for the C. elegans ORFeome. Genome Res (2004) 1.47
The modENCODE Data Coordination Center: lessons in harvesting comprehensive experimental details. Database (Oxford) (2011) 1.39
GMODWeb: a web framework for the Generic Model Organism Database. Genome Biol (2008) 1.38
Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biol (2006) 1.25
Cloud-based uniform ChIP-Seq processing tools for modENCODE and ENCODE. BMC Genomics (2013) 1.18
Identification of a nematode chemosensory gene family. Proc Natl Acad Sci U S A (2004) 1.14
Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer. Mol Cell Proteomics (2012) 1.08
Localizing triplet periodicity in DNA and cDNA sequences. BMC Bioinformatics (2010) 0.99
Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. Int J Cancer (2013) 0.87
WormBase: methods for data mining and comparative genomics. Methods Mol Biol (2006) 0.82
Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer. Hum Genomics (2013) 0.82
Gallus GBrowse: a unified genomic database for the chicken. Nucleic Acids Res (2007) 0.81
Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns. Nature (2016) 0.75
Modeling the evolution dynamics of exon-intron structure with a general random fragmentation process. BMC Evol Biol (2013) 0.75