Published in Biochem Pharmacol on December 01, 2004
Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system. J Venom Anim Toxins Incl Trop Dis (2014) 0.83
The longevity of Th2 humoral response induced by proteases natterins requires the participation of long-lasting innate-like B cells and plasma cells in spleen. PLoS One (2013) 0.82
TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells. PLoS One (2013) 0.81
Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer. PLoS Negl Trop Dis (2013) 0.80
Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation. Int J Exp Pathol (2009) 0.78
The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A. PLoS One (2013) 0.77
Bioactive components in fish venoms. Toxins (Basel) (2015) 0.77
A multifunctional serine protease primes the malaria parasite for red blood cell invasion. EMBO J (2009) 1.67
Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development. J Biol Chem (2003) 1.35
The route of antimicrobial resistance from the hospital effluent to the environment: focus on the occurrence of KPC-producing Aeromonas spp. and Enterobacteriaceae in sewage. Diagn Microbiol Infect Dis (2013) 1.30
Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major. Autophagy (2009) 1.26
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling. J Biol Chem (2008) 1.20
Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates. Nat Protoc (2008) 1.18
Membrane fusion induced by vesicular stomatitis virus depends on histidine protonation. J Biol Chem (2003) 1.17
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing. FEBS Lett (2007) 1.16
ATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moiety. J Biol Chem (2004) 1.15
Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein. Biochem J (2003) 1.12
Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates. J Biol Chem (2002) 1.12
Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers. Biol Chem (2007) 1.10
Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species. J Biol Chem (2005) 1.05
A glimpse on biological activities of tellurium compounds. An Acad Bras Cienc (2009) 1.03
Detection of SPM-1-producing Pseudomonas aeruginosa and class D β-lactamase-producing Acinetobacter baumannii isolates by use of liquid chromatography-mass spectrometry and matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol (2012) 1.03
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases. J Biol Chem (2009) 1.01
Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects. J Biol Chem (2005) 1.01
Metagenomic analysis of a tropical composting operation at the são paulo zoo park reveals diversity of biomass degradation functions and organisms. PLoS One (2013) 0.99
Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor. J Biol Chem (2011) 0.99
Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. Proc Natl Acad Sci U S A (2005) 0.99
Design and use of highly specific substrates of neutrophil elastase and proteinase 3. Am J Respir Cell Mol Biol (2003) 0.99
Cathepsin X binds to cell surface heparan sulfate proteoglycans. Arch Biochem Biophys (2005) 0.99
A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay. Nat Protoc (2006) 0.99
T-cell molecular mimicry in Chagas disease: identification and partial structural analysis of multiple cross-reactive epitopes between Trypanosoma cruzi B13 and cardiac myosin heavy chain. J Autoimmun (2005) 0.99
Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil. Trans R Soc Trop Med Hyg (2004) 0.99
Cysteine-protease activity elicited by Ca2+ stimulus in Plasmodium. Mol Biochem Parasitol (2005) 0.98
Mutation of active site residues of insulin-degrading enzyme alters allosteric interactions. J Biol Chem (2005) 0.97
Purification, characterization and substrate specificity of a trypsin from the Amazonian fish tambaqui (Colossoma macropomum). Biochem Biophys Res Commun (2010) 0.96
Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain. J Biol Chem (2001) 0.96
Amylolytic microorganism from são paulo zoo composting: isolation, identification, and amylase production. Enzyme Res (2011) 0.94
Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase. A kinetic and molecular modeling analysis. J Biol Chem (2006) 0.94
Crotamine mediates gene delivery into cells through the binding to heparan sulfate proteoglycans. J Biol Chem (2007) 0.94
A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions. Arch Biochem Biophys (2009) 0.93
Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: assays with human cathepsin B. Anal Biochem (2004) 0.93
Role of the bradykinin B2 receptor for the local and systemic inflammatory response that follows severe reperfusion injury. Br J Pharmacol (2003) 0.92
Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates. Eur J Biochem (2002) 0.92
Probing the interaction between vesicular stomatitis virus and phosphatidylserine. Eur Biophys J (2005) 0.91
Identification of the allosteric regulatory site of insulysin. PLoS One (2011) 0.90
Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth. Mol Cancer (2007) 0.89
Increased expression of acetylcholine receptors in the diaphragm muscle of MDX mice. Muscle Nerve (2008) 0.88
In vitro and in vivo degradation of Abeta peptide by peptidases coupled to erythrocytes. Peptides (2007) 0.88
On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca2+ dependence, and cyt c release. Biochem Pharmacol (2010) 0.88
Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates. J Biol Chem (2002) 0.88
Identification of bradykinins in solitary wasp venoms. Toxicon (2002) 0.88
Hydrolytic properties and substrate specificity of the foot-and-mouth disease leader protease. Biochemistry (2009) 0.88
Immune evasion by pathogenic Leptospira strains: the secretion of proteases that directly cleave complement proteins. J Infect Dis (2013) 0.88
Inhibition of neutrophil elastase by alpha1-protease inhibitor at the surface of human polymorphonuclear neutrophils. J Immunol (2005) 0.88
Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L. Arch Biochem Biophys (2004) 0.87
Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L. Biol Chem (2005) 0.87
Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate. Arterioscler Thromb Vasc Biol (2013) 0.87
S3 to S3' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates. Biochem J (2003) 0.87
Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates. Biochem J (2005) 0.87
Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice. J Neuroinflammation (2008) 0.87
Mammalian pitrilysin: substrate specificity and mitochondrial targeting. Biochemistry (2009) 0.87
Investigating the substrate specificity and oligomerisation of the leader protease of foot and mouth disease virus using NMR. J Mol Biol (2007) 0.87
The natural cell-penetrating peptide crotamine targets tumor tissue in vivo and triggers a lethal calcium-dependent pathway in cultured cells. Mol Pharm (2011) 0.87
Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus. Biochem Pharmacol (2009) 0.87
Nardilysin cleaves peptides at monobasic sites. Biochemistry (2003) 0.87
Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates. Biochem J (2002) 0.86
Interaction between dengue virus fusion peptide and lipid bilayers depends on peptide clustering. Mol Membr Biol (2008) 0.86
Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw. Eur J Pharmacol (2007) 0.86
High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1-7) levels in the adipose tissue. Regul Pept (2010) 0.86
Biochemical and functional characterization of a metalloprotease from the thermophilic fungus Thermoascus aurantiacus. J Agric Food Chem (2009) 0.86
Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides. Biochem J (2002) 0.85
Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization. Toxicon (2008) 0.85
Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta. J Biol Chem (2005) 0.85
A structure-based site-directed mutagenesis study on the neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) catalysis. FEBS Lett (2003) 0.85
Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides for defining substrate specificity of the angiotensin I-converting enzyme and development of selective C-domain substrates. Biochemistry (2004) 0.85
Fluorescence resonance energy transfer (FRET) peptides and cycloretro-inverso peptides derived from bradykinin as substrates and inhibitors of prolyl oligopeptidase. Peptides (2007) 0.85
Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assay. PLoS Negl Trop Dis (2013) 0.85
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals. Clin Vaccine Immunol (2007) 0.84
Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1. J Biol Chem (2010) 0.84
Inflammatory pathogenesis of snake venom metalloproteinase-induced skin necrosis. Eur J Immunol (2003) 0.84
Purification, characterization, and specificity determination of a new serine protease secreted by Penicillium waksmanii. Appl Biochem Biotechnol (2012) 0.84
Syndecan-4 contributes to endothelial tubulogenesis through interactions with two motifs inside the pro-angiogenic N-terminal domain of thrombospondin-1. J Cell Physiol (2008) 0.83
The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice. Br J Pharmacol (2010) 0.83
Modeling the Trypanosoma cruzi Tc85-11 protein and mapping the laminin-binding site. Biochem Biophys Res Commun (2004) 0.83
The substrate specificity of cruzipain 2, a cysteine protease isoform from Trypanosoma cruzi. FEMS Microbiol Lett (2006) 0.82
The use of Fluorescence Resonance Energy Transfer (FRET) peptides for measurement of clinically important proteolytic enzymes. An Acad Bras Cienc (2009) 0.82
Internally quenched fluorescent peptide libraries with randomized sequences designed to detect endopeptidases. Anal Biochem (2011) 0.82
Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth. Mol Cell Neurosci (2010) 0.82
Protective effect of the organotelluroxetane RF-07 in pilocarpine-induced status epilepticus. Neurobiol Dis (2008) 0.82
Cathepsin D-mediated yolk protein degradation is blocked by acid phosphatase inhibitors. Arch Biochem Biophys (2005) 0.82
Angiotensin I-converting enzyme inhibitor peptides derived from the endostatin-containing NC1 fragment of human collagen XVIII. Biol Chem (2006) 0.82
Involvement of proteinase-activated receptors 1 and 2 in spreading and phagocytosis by murine adherent peritoneal cells: modulation by the C-terminal of S100A9 protein. Eur J Pharmacol (2009) 0.82
The intracellular distribution and secretion of endopeptidases 24.15 (EC 3.4.24.15) and 24.16 (EC 3.4.24.16). Protein Pept Lett (2004) 0.82
Lytic activity and structural differences of amphipathic peptides derived from trialysin. Biochemistry (2006) 0.82
T cell epitope characterization in tandemly repetitive Trypanosoma cruzi B13 protein. Microbes Infect (2005) 0.81
Similar intracellular peptide profile of TAP1/β2 microglobulin double-knockout mice and C57BL/6 wild-type mice as revealed by peptidomic analysis. AAPS J (2010) 0.81
Calcium modulates endopeptidase 24.15 (EC 3.4.24.15) membrane association, secondary structure and substrate specificity. FEBS J (2005) 0.81
Structural and biological characterization of Nattectin, a new C-type lectin from the venomous fish Thalassophryne nattereri. Biochimie (2011) 0.81