Published in Protein Sci on November 01, 2004
The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics. PLoS Comput Biol (2011) 0.99
Mechanism of glycan receptor recognition and specificity switch for avian, swine, and human adapted influenza virus hemagglutinins: a molecular dynamics perspective. J Am Chem Soc (2009) 0.97
Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex. Biochemistry (2008) 0.92
Backbone dynamics of the 18.5 kDa isoform of myelin basic protein reveals transient alpha-helices and a calmodulin-binding site. Biophys J (2008) 0.88
Action of melatonin on squamous cell carcinoma and other tumors of the oral cavity (Review). Oncol Lett (2014) 0.79
NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR (1995) 93.94
Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. J Biomol NMR (1992) 17.71
1H, 13C and 15N chemical shift referencing in biomolecular NMR. J Biomol NMR (1995) 15.76
The program XEASY for computer-supported NMR spectral analysis of biological macromolecules. J Biomol NMR (1995) 12.25
The statistical-thermodynamic basis for computation of binding affinities: a critical review. Biophys J (1997) 7.64
Calcium--a life and death signal. Nature (1998) 6.35
Measurement of J and dipolar couplings from simplified two-dimensional NMR spectra. J Magn Reson (1998) 5.83
A novel approach for sequential assignment of 1H, 13C, and 15N spectra of proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin. Biochemistry (1990) 5.01
Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation. J Magn Reson B (1995) 4.93
Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex. Science (1992) 4.89
Structure of calmodulin refined at 2.2 A resolution. J Mol Biol (1988) 4.65
Automated docking of substrates to proteins by simulated annealing. Proteins (1990) 4.49
Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible. Biochemistry (1992) 4.25
Calmodulin in action: diversity in target recognition and activation mechanisms. Cell (2002) 3.77
Mapping protein-protein interactions in solution by NMR spectroscopy. Biochemistry (2002) 3.31
Molecular and structural basis of target recognition by calmodulin. Annu Rev Biophys Biomol Struct (1995) 3.31
Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev (1990) 2.88
On the calculation of absolute macromolecular binding free energies. Proc Natl Acad Sci U S A (2002) 2.17
Heteronuclear three-dimensional NMR spectroscopy of the inflammatory protein C5a. Biochemistry (1989) 1.63
Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy. Curr Top Med Chem (2002) 1.51
Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships. J Pharmacol Exp Ther (1982) 1.47
Interaction of drugs with calmodulin. Biochemical, pharmacological and clinical implications. Biochem Pharmacol (1982) 1.43
Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition. J Mol Biol (1998) 1.38
Structure of a recombinant calmodulin from Drosophila melanogaster refined at 2.2-A resolution. J Biol Chem (1991) 1.38
Trifluoperazine-induced conformational change in Ca(2+)-calmodulin. Nat Struct Biol (1994) 1.35
Structure and dynamics of calmodulin in solution. Biophys J (1998) 1.27
Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination. Biochemistry (1998) 1.20
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex. Biochemistry (1994) 1.20
Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies. Biochemistry (1998) 1.02
Structural organization of multiple rat calmodulin genes. J Mol Biol (1989) 0.98
Nuclear localization of melatonin in different mammalian tissues: immunocytochemical and radioimmunoassay evidence. J Cell Biochem (1993) 0.93
NMR approaches for monitoring domain orientations in calcium-binding proteins in solution using partial replacement of Ca2+ by Tb3+. FEBS Lett (1999) 0.90
Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cells. J Pineal Res (2002) 0.90
Cations and calmodulin in normal and neoplastic cell growth regulation. Can J Biochem Cell Biol (1983) 0.89
Physiological concentrations of melatonin inhibit the nitridergic pathway in the Syrian hamster retina. J Pineal Res (2002) 0.89
Binding of 3H-melatonin to calmodulin. Life Sci (1993) 0.89
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin. J Cell Biochem (1997) 0.88
Evidence for calmodulin inter-domain compaction in solution induced by W-7 binding. FEBS Lett (1999) 0.88
Complexes formed between calmodulin and the antagonists J-8 and TFP in solution. Biochemistry (1996) 0.88
Calmodulin antagonists of improved potency and specificity for use in the study of calmodulin biochemistry. Biochem Pharmacol (1988) 0.85
Effects of melatonin on microtubule assembly depend on hormone concentration: role of melatonin as a calmodulin antagonist. J Pineal Res (1994) 0.84
A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies. J Mol Biol (2000) 0.84
Differential inhibition of calcium-dependent and calmodulin-dependent enzymes by drug-calmodulin adducts. Mol Pharmacol (1990) 0.83
Structural and energetic parameters of Ca2+ binding to peptides and proteins. Biopolymers (1988) 0.83
In vitro inhibition of Ca2+/calmodulin-dependent kinase II activity by melatonin. Biochim Biophys Acta (1996) 0.83
Structure-related inhibition of calmodulin-dependent neuronal nitric-oxide synthase activity by melatonin and synthetic kynurenines. Mol Pharmacol (2000) 0.82
Melatonin and serotonin interactions with calmodulin: NMR, spectroscopic and biochemical studies. Biochim Biophys Acta (1998) 0.81
The effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo. Chin Med J (Engl) (2002) 0.80
Melatonin site and mechanism of action: single or multiple? J Pineal Res (1997) 0.79
Future of melatonin as a therapeutic agent. Neuro Endocrinol Lett (2002) 0.78
Molecular dynamics simulation of the calmodulin-trifluoperazine complex in aqueous solution. Biopolymers (2001) 0.77
Lack of calmodulin antagonism of melatonin in T-lymphocyte activation. Life Sci (1998) 0.77
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat Struct Mol Biol (2008) 5.32
Structure of mammalian AMPK and its regulation by ADP. Nature (2011) 4.27
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature (2008) 3.79
Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature (2007) 3.26
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet (2010) 2.66
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A (2008) 2.58
Physiology of circadian entrainment. Physiol Rev (2010) 2.51
Specificity and mechanism of the histone methyltransferase Pr-Set7. Genes Dev (2005) 2.50
Receptor binding by an H7N9 influenza virus from humans. Nature (2013) 2.33
Crystal structure and functional analysis of the histone methyltransferase SET7/9. Cell (2002) 2.27
Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin. Proc Natl Acad Sci U S A (2012) 2.18
The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase. J Biol Chem (2008) 2.14
Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS. Nat Struct Mol Biol (2009) 2.08
Key features of the interaction between Pcf11 CID and RNA polymerase II CTD. Nat Struct Mol Biol (2005) 2.07
Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins. FEBS Lett (2002) 1.78
From Alzheimer to Huntington: why is a structural understanding so difficult? EMBO J (2003) 1.68
The pathogenesis of Friedreich ataxia and the structure and function of frataxin. J Neurol (2009) 1.68
The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition. Proc Natl Acad Sci U S A (2005) 1.62
Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly. Nat Commun (2010) 1.56
Solution structure of the bacterial frataxin ortholog, CyaY: mapping the iron binding sites. Structure (2004) 1.55
G-quartet-dependent recognition between the FMRP RGG box and RNA. RNA (2003) 1.54
Dual acylation of the 45 kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites. Mol Biochem Parasitol (2006) 1.53
The catalytic mechanism of peptidylglycine alpha-hydroxylating monooxygenase investigated by computer simulation. J Am Chem Soc (2006) 1.49
Kinetics of different processes in human insulin amyloid formation. J Mol Biol (2006) 1.48
Retinal oxidative stress induced by high intraocular pressure. Free Radic Biol Med (2004) 1.48
The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction. Structure (2006) 1.45
The structure of Lethocerus troponin C: insights into the mechanism of stretch activation in muscles. Structure (2007) 1.45
Receptor binding by a ferret-transmissible H5 avian influenza virus. Nature (2013) 1.43
Iron binding and oxidation kinetics in frataxin CyaY of Escherichia coli. J Mol Biol (2004) 1.42
Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3. J Mol Biol (2004) 1.41
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase. Cell Metab (2011) 1.37
Polyglutamine is not all: the functional role of the AXH domain in the ataxin-1 protein. J Mol Biol (2005) 1.36
Acetate kinase: not just a bacterial enzyme. Trends Microbiol (2006) 1.33
Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. J Biol Chem (2005) 1.32
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient. J Mol Biol (2007) 1.31
SCA3: neurological features, pathogenesis and animal models. Cerebellum (2008) 1.31
Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease. J Biol Chem (2011) 1.26
Structure of a Mycobacterium tuberculosis NusA-RNA complex. EMBO J (2005) 1.25
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly. EMBO Rep (2006) 1.24
Branching in amyloid fibril growth. Biophys J (2009) 1.21
The MTIP-myosin A complex in blood stage malaria parasites. J Mol Biol (2005) 1.20
Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis. Biochemistry (2012) 1.19
Unbiased cold denaturation: low- and high-temperature unfolding of yeast frataxin under physiological conditions. J Am Chem Soc (2007) 1.17
Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites. Biopolymers (2009) 1.17
Domain architecture of the polyglutamine protein ataxin-3: a globular domain followed by a flexible tail. FEBS Lett (2003) 1.16
The interplay between PolyQ and protein context delays aggregation by forming a reservoir of protofibrils. PLoS One (2006) 1.15
The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre. J Mol Biol (2004) 1.15
Structure of the complex of calmodulin with the target sequence of calmodulin-dependent protein kinase I: studies of the kinase activation mechanism. Biochemistry (2002) 1.14
The factors governing the thermal stability of frataxin orthologues: how to increase a protein's stability. Biochemistry (2004) 1.13
Functional interactions as a survival strategy against abnormal aggregation. FASEB J (2010) 1.13
Multiple-steering QM-MM calculation of the free energy profile in chorismate mutase. J Am Chem Soc (2005) 1.13
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. J Biol Chem (2010) 1.12
Protein stability in nanocages: a novel approach for influencing protein stability by molecular confinement. J Mol Biol (2004) 1.12
Studies of structural changes in the M2 proton channel of influenza A virus by tryptophan fluorescence. Virus Res (2004) 1.12
Clinical and genetic aspects of Bernard-Soulier syndrome: searching for genotype/phenotype correlations. Haematologica (2010) 1.11
Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin. Eur J Biochem (2004) 1.11
Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors. PLoS One (2009) 1.11
Understanding the binding properties of an unusual metal-binding protein--a study of bacterial frataxin. FEBS J (2007) 1.10
Kinetics of insulin aggregation: disentanglement of amyloid fibrillation from large-size cluster formation. Biophys J (2006) 1.09
Y65C missense mutation in the WW domain of the Golabi-Ito-Hall syndrome protein PQBP1 affects its binding activity and deregulates pre-mRNA splicing. J Biol Chem (2010) 1.09
Molecular basis of FIR-mediated c-myc transcriptional control. Nat Struct Mol Biol (2010) 1.07
Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1. J Biol Chem (2003) 1.07
Protofibril formation of amyloid beta-protein at low pH via a non-cooperative elongation mechanism. J Biol Chem (2005) 1.07
Ligand-induced dynamical regulation of NO conversion in Mycobacterium tuberculosis truncated hemoglobin-N. Proteins (2006) 1.06
Conformational stability of human frataxin and effect of Friedreich's ataxia-related mutations on protein folding. Biochem J (2006) 1.05
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins. J Am Chem Soc (2005) 1.05
Heme protein oxygen affinity regulation exerted by proximal effects. J Am Chem Soc (2006) 1.03
Temperature jump kinetic study of the stability of apo-calmodulin. Biophys Chem (2002) 1.02
Bacterial IscU is a well folded and functional single domain protein. Eur J Biochem (2004) 1.02
Of the vulnerability of orphan complex proteins: the case study of the E. coli IscU and IscS proteins. Protein Expr Purif (2010) 1.02
Aromatic-aromatic interactions in proteins: beyond the dimer. J Chem Inf Model (2011) 1.01
An elastically tethered viscous load imposes a regular gait on the motion of myosin-V. Simulation of the effect of transient force relaxation on a stochastic process. J R Soc Interface (2006) 1.01
In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency. Cell Rep (2013) 1.00
MYH9-related disease: five novel mutations expanding the spectrum of causative mutations and confirming genotype/phenotype correlations. Eur J Med Genet (2012) 1.00
Role of dimerization in KH/RNA complexes: the example of Nova KH3. Biochemistry (2002) 1.00
Prion fibrillization is mediated by a native structural element that comprises helices H2 and H3. J Biol Chem (2010) 1.00
Aggregation of a multidomain protein: a coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stress. Protein Sci (2010) 1.00
Retinal neuroprotection against ischemia-reperfusion damage induced by postconditioning. Invest Ophthalmol Vis Sci (2009) 0.99
Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy. Structure (2004) 0.99
Theoretical study of the truncated hemoglobin HbN: exploring the molecular basis of the NO detoxification mechanism. J Am Chem Soc (2005) 0.99
Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3. PLoS One (2010) 0.99
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum. J Biol Chem (2003) 0.99
82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization. Hum Mol Genet (2003) 0.99
A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease. Protein Eng Des Sel (2011) 0.99
A new experimental model of glaucoma in rats through intracameral injections of hyaluronic acid. Exp Eye Res (2005) 0.99
Cold denaturation of yeast frataxin offers the clue to understand the effect of alcohols on protein stability. J Am Chem Soc (2008) 0.98
Changes in the hemagglutinin of H5N1 viruses during human infection--influence on receptor binding. Virology (2013) 0.98
KH domains with impaired nucleic acid binding as a tool for functional analysis. Nucleic Acids Res (2012) 0.98
Regulating the contraction of insect flight muscle. J Muscle Res Cell Motil (2011) 0.98
Modeling heme proteins using atomistic simulations. Phys Chem Chem Phys (2006) 0.97
Spectrum of the mutations in Bernard-Soulier syndrome. Hum Mutat (2014) 0.97
The role of interruptions in polyQ in the pathology of SCA1. PLoS Genet (2013) 0.96
Ferredoxin competes with bacterial frataxin in binding to the desulfurase IscS. J Biol Chem (2013) 0.96
Fluorescent ligands for the hemagglutinin of influenza A: synthesis and ligand binding assays. Bioconjug Chem (2007) 0.96
YfhJ, a molecular adaptor in iron-sulfur cluster formation or a frataxin-like protein? Structure (2006) 0.95