Phylogenetic analysis of the formin homology 2 domain.

A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol (2010) 5.33

Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45

The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol (2011) 2.22

Review of the mechanism of processive actin filament elongation by formins. Cell Motil Cytoskeleton (2009) 2.12

The regulation of mDia1 by autoinhibition and its release by Rho*GTP. EMBO J (2005) 2.10

Regulatory interactions between two actin nucleators, Spire and Cappuccino. J Cell Biol (2007) 2.08

The role of the FH1 domain and profilin in formin-mediated actin-filament elongation and nucleation. Curr Biol (2007) 2.01

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1. J Cell Biol (2006) 1.99

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96

Self-assembly of filopodia-like structures on supported lipid bilayers. Science (2010) 1.87

Distinct ceramide synthases regulate polarized growth in the filamentous fungus Aspergillus nidulans. Mol Biol Cell (2006) 1.69

Regulation of the formin for3p by cdc42p and bud6p. Mol Biol Cell (2007) 1.68

INF2 is an endoplasmic reticulum-associated formin protein. J Cell Sci (2009) 1.67

Yeast formins Bni1 and Bnr1 utilize different modes of cortical interaction during the assembly of actin cables. Mol Biol Cell (2007) 1.46

The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Curr Biol (2011) 1.39

Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules. Mol Biol Cell (2011) 1.31

Regulation and targeting of the fission yeast formin cdc12p in cytokinesis. Mol Biol Cell (2008) 1.31

The cytokinesis formins from the nematode worm and fission yeast differentially mediate actin filament assembly. J Biol Chem (2008) 1.30

Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol (2007) 1.29

Interaction of the N- and C-terminal autoregulatory domains of FRL2 does not inhibit FRL2 activity. J Biol Chem (2008) 1.28

Sequence and comparative genomic analysis of actin-related proteins. Mol Biol Cell (2005) 1.28

Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem (2008) 1.27

The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed ends. J Biol Chem (2011) 1.24

Filopodia initiation: focus on the Arp2/3 complex and formins. Cell Adh Migr (2011) 1.23

Assembly of filopodia by the formin FRL2 (FMNL3). Cytoskeleton (Hoboken) (2010) 1.20

Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins. J Biol Chem (2009) 1.18

Dynamic regulation of sarcomeric actin filaments in striated muscle. Cytoskeleton (Hoboken) (2010) 1.17

Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17

Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing. J Biol Chem (2009) 1.15

Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc Natl Acad Sci U S A (2010) 1.10

From function to shape: a novel role of a formin in morphogenesis of the fungus Ashbya gossypii. Mol Biol Cell (2005) 1.09

Energetic requirements for processive elongation of actin filaments by FH1FH2-formins. J Biol Chem (2009) 1.08

Roots of angiosperm formins: the evolutionary history of plant FH2 domain-containing proteins. BMC Evol Biol (2008) 1.07

Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture. Mol Biol Cell (2011) 1.07

Proper cellular reorganization during Drosophila spermatid individualization depends on actin structures composed of two domains, bundles and meshwork, that are differentially regulated and have different functions. Mol Biol Cell (2008) 1.05

INF1 is a novel microtubule-associated formin. Mol Biol Cell (2008) 1.04

Molecular mechanisms of cell-cell spread of intracellular bacterial pathogens. Open Biol (2013) 1.04

Origins and evolution of the formin multigene family that is involved in the formation of actin filaments. Mol Biol Evol (2008) 1.03

Z-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans. J Cell Biol (2012) 1.03

Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing. J Biol Chem (2012) 0.99

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector. PLoS Pathog (2009) 0.96

Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM. J Biol Chem (2010) 0.95

The formin FRL1 (FMNL1) is an essential component of macrophage podosomes. Cytoskeleton (Hoboken) (2010) 0.95

The functionally distinct fission yeast formins have specific actin-assembly properties. Mol Biol Cell (2011) 0.95

Bi-modal regulation of a formin by srGAP2. J Biol Chem (2010) 0.95

Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins. PLoS One (2010) 0.93

Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93

Immune pathology associated with altered actin cytoskeleton regulation. Autoimmunity (2010) 0.92

Formins in development: orchestrating body plan origami. Biochim Biophys Acta (2008) 0.91

Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains. Mol Biol Cell (2012) 0.91

Critical roles for multiple formins during cardiac myofibril development and repair. Mol Biol Cell (2014) 0.90

New insights into the role of plant formins: regulating the organization of the actin and microtubule cytoskeleton. Protoplasma (2012) 0.90

RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis. Cell Cycle (2015) 0.89

Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration. Mol Biol Cell (2014) 0.89

INF2-mediated severing through actin filament encirclement and disruption. Curr Biol (2014) 0.89

Formins and membranes: anchoring cortical actin to the cell wall and beyond. Front Plant Sci (2013) 0.88

Actin nucleators in the nucleus: an emerging theme. J Cell Sci (2012) 0.87

Metastasis suppressor microRNA-335 targets the formin family of actin nucleators. PLoS One (2013) 0.87

Entamoeba histolytica encodes unique formins, a subset of which regulates DNA content and cell division. Infect Immun (2008) 0.87

The multiplicity of human formins: Expression patterns in cells and tissues. Cytoskeleton (Hoboken) (2013) 0.85

FORMIN a link between kinetochores and microtubule ends. Trends Cell Biol (2011) 0.85

The role of formin tails in actin nucleation, processive elongation, and filament bundling. J Biol Chem (2014) 0.84

Formins: emerging players in the dynamic plant cell cortex. Scientifica (Cairo) (2012) 0.83

The yeast formin Bnr1p has two localization regions that show spatially and temporally distinct association with septin structures. Mol Biol Cell (2010) 0.83

RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol (2015) 0.82

Formin' cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics. Commun Integr Biol (2014) 0.82

Interaction between microtubules and the Drosophila formin Cappuccino and its effect on actin assembly. J Biol Chem (2013) 0.81

Regulation of the formin Cappuccino is critical for polarity of Drosophila oocytes. Cytoskeleton (Hoboken) (2015) 0.80

The role of the formin gene fhod-1 in C. elegans embryonic morphogenesis. Worm (2013) 0.80

Comparative gene expression analysis of the fmnl family of formins during zebrafish development and implications for tissue specific functions. Gene Expr Patterns (2012) 0.80

The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion. Mol Biol Cell (2014) 0.80

DAAM family members leading a novel path into formin research. Commun Integr Biol (2011) 0.79

The effects of formins on the conformation of subdomain 1 in actin filaments. J Photochem Photobiol B (2009) 0.78

Centrosome polarization in T cells: a task for formins. Front Immunol (2013) 0.78

Revisiting the Phylogeny of the Animal Formins: Two New Subtypes, Relationships with Multiple Wing Hairs Proteins, and a Lost Human Formin. PLoS One (2016) 0.77

Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure (2015) 0.77

Formins: Actin nucleators that regulate cytoskeletal dynamics during spermatogenesis. Spermatogenesis (2015) 0.77

Formin 1 Regulates Microtubule and F-Actin Organization to Support Spermatid Transport During Spermatogenesis in the Rat Testis. Endocrinology (2016) 0.77

Uncoupling apical constriction from tissue invagination. Elife (2017) 0.75

Human Macrophages Utilize the Podosome Formin FMNL1 for Adhesion and Migration. Cellbio (Irvine, Calif) (2015) 0.75

Structural and Biochemical Basis for the Inhibitory Effect of Liprin-α3 on Mouse Diaphanous 1 (mDia1) Function. J Biol Chem (2015) 0.75

High FMNL3 expression promotes nasopharyngeal carcinoma cell metastasis: role in TGF-β1-induced epithelia-to-mesenchymal transition. Sci Rep (2017) 0.75

On the origin of non-membrane-bound organelles, and their physiological function. J Theor Biol (2017) 0.75

OsFH15, a class I formin, interacts with microfilaments and microtubules to regulate grain size via affecting cell expansion in rice. Sci Rep (2017) 0.75

Daam1 regulates fascin for actin assembly in mouse oocyte meiosis. Cell Cycle (2017) 0.75

The Pfam protein families database. Nucleic Acids Res (2002) 51.34

Predicting coiled coils from protein sequences. Science (1991) 38.18

A millennial myosin census. Mol Biol Cell (2001) 6.13

The origin and evolution of model organisms. Nat Rev Genet (2002) 5.98

Role of formins in actin assembly: nucleation and barbed-end association. Science (2002) 5.47

Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science (1997) 5.27

An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52

Myosins: a diverse superfamily. Biochim Biophys Acta (2000) 4.30

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. Curr Biol (2003) 3.64

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51

The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin. J Cell Biol (2003) 3.40

Phylogenetic analysis in molecular evolutionary genetics. Annu Rev Genet (1996) 3.39

The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol (2003) 3.13

Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development (1994) 3.05

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain. J Biol Chem (2000) 2.86

A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77

The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments. J Biol Chem (2004) 2.54

A myosin family tree. J Cell Sci (2000) 2.30

Formin-induced nucleation of actin filaments. Curr Opin Cell Biol (2004) 2.12

'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature (1990) 1.98

Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus. Genes Dev (1995) 1.87

FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation. J Cell Biol (1998) 1.77

FH proteins as cytoskeletal organizers. Trends Cell Biol (1998) 1.75

The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell (2004) 1.74

Molecular evolution of the actin family. J Cell Sci (2002) 1.42

Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. J Neurosci (2002) 1.17

The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element. J Biol Chem (2001) 1.15

Formin homology 2 domains occur in multiple contexts in angiosperms. BMC Genomics (2004) 1.11

Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region. Cell Tissue Res (1999) 1.08

Systematic searches for molecular synapomorphies in model metazoan genomes give some support for Ecdysozoa after accounting for the idiosyncrasies of Caenorhabditis elegans. Evol Dev (2004) 1.01

Identification and characterization of a protein containing formin homology (FH1/FH2) domains. Gene (1999) 0.92

Episodic radiations in the fly tree of life. Proc Natl Acad Sci U S A (2011) 7.03

The Cambrian conundrum: early divergence and later ecological success in the early history of animals. Science (2011) 5.15

The dynamic genome of Hydra. Nature (2010) 4.00

The deep evolution of metazoan microRNAs. Evol Dev (2009) 3.56

Acoelomorph flatworms are deuterostomes related to Xenoturbella. Nature (2011) 3.06

MicroRNAs and the advent of vertebrate morphological complexity. Proc Natl Acad Sci U S A (2008) 3.00

The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint. J Exp Zool B Mol Dev Evol (2006) 2.63

microRNAs reveal the interrelationships of hagfish, lampreys, and gnathostomes and the nature of the ancestral vertebrate. Proc Natl Acad Sci U S A (2010) 2.25

A congruent solution to arthropod phylogeny: phylogenomics, microRNAs and morphology support monophyletic Mandibulata. Proc Biol Sci (2010) 2.20

Phylogenetic-signal dissection of nuclear housekeeping genes supports the paraphyly of sponges and the monophyly of Eumetazoa. Mol Biol Evol (2009) 1.95

MicroRNAs and phylogenomics resolve the relationships of Tardigrada and suggest that velvet worms are the sister group of Arthropoda. Proc Natl Acad Sci U S A (2011) 1.87

Normalization and standardization of electronic health records for high-throughput phenotyping: the SHARPn consortium. J Am Med Inform Assoc (2013) 1.64

MicroRNAs support a turtle + lizard clade. Biol Lett (2011) 1.62

microRNA complements in deuterostomes: origin and evolution of microRNAs. Evol Dev (2011) 1.41

Unusual gene order and organization of the sea urchin hox cluster. J Exp Zool B Mol Dev Evol (2006) 1.34

Paleogenomics of echinoderms. Science (2006) 1.32

Phylogenetic distribution of microRNAs supports the basal position of acoel flatworms and the polyphyly of Platyhelminthes. Evol Dev (2007) 1.27

A molecular palaeobiological hypothesis for the origin of aplacophoran molluscs and their derivation from chiton-like ancestors. Proc Biol Sci (2011) 1.23

Resolving phylogenetic signal from noise when divergence is rapid: a new look at the old problem of echinoderm class relationships. Mol Phylogenet Evol (2011) 1.18

Do miRNAs have a deep evolutionary history? Bioessays (2012) 1.17

miRNAs: small genes with big potential in metazoan phylogenetics. Mol Biol Evol (2013) 1.13

Molecular paleobiological insights into the origin of the Brachiopoda. Evol Dev (2011) 1.05

MicroRNAs resolve an apparent conflict between annelid systematics and their fossil record. Proc Biol Sci (2009) 1.03

Toward consilience in reptile phylogeny: miRNAs support an archosaur, not lepidosaur, affinity for turtles. Evol Dev (2014) 1.02

Molecular paleoecology: using gene regulatory analysis to address the origins of complex life cycles in the late Precambrian. Evol Dev (2007) 1.01

Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks. Dev Biol (2003) 0.98

Genetic organization and embryonic expression of the ParaHox genes in the sea urchin S. purpuratus: insights into the relationship between clustering and colinearity. Dev Biol (2006) 0.98

Reconstruction of family-level phylogenetic relationships within Demospongiae (Porifera) using nuclear encoded housekeeping genes. PLoS One (2013) 0.98

Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo. Dev Biol (2004) 0.93

Developmental expression of COE across the Metazoa supports a conserved role in neuronal cell-type specification and mesodermal development. Dev Genes Evol (2010) 0.89

Testing putative hemichordate homologues of the chordate dorsal nervous system and endostyle: expression of NK2.1 (TTF-1) in the acorn worm Ptychodera flava (Hemichordata, Ptychoderidae). Evol Dev (2002) 0.86

The identification of microRNAs in calcisponges: independent evolution of microRNAs in basal metazoans. J Exp Zool B Mol Dev Evol (2013) 0.81

CD2AP regulates SUMOylation of CIN85 in podocytes. Mol Cell Biol (2011) 0.81

Incorporating expert terminology and disease risk factors into consumer health vocabularies. Pac Symp Biocomput (2013) 0.80

Representing the ClaML-based ICD10 in LexGrid terminology model. AMIA Annu Symp Proc (2008) 0.75