Published in EMBO J on November 17, 2005
A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol (2010) 5.33
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis. Nat Genet (2009) 3.20
Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis. J Am Soc Nephrol (2011) 2.63
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation. J Cell Biol (2007) 2.15
Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1. J Cell Biol (2006) 1.99
Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J Biol Chem (2008) 1.97
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev (2007) 1.77
Regulation of the formin for3p by cdc42p and bud6p. Mol Biol Cell (2007) 1.68
INF2 is an endoplasmic reticulum-associated formin protein. J Cell Sci (2009) 1.67
The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Curr Biol (2011) 1.39
Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle. J Cardiovasc Pharmacol Ther (2008) 1.34
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol (2007) 1.29
Structural insights into de novo actin polymerization. Curr Opin Struct Biol (2010) 1.28
The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells. EMBO J (2008) 1.28
Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem (2008) 1.27
Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex. Small GTPases (2011) 1.19
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17
An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Curr Biol (2010) 1.15
Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains. Mol Biol Cell (2010) 1.10
DAAM1 is a formin required for centrosome re-orientation during cell migration. PLoS One (2010) 1.09
Formins as effector proteins of Rho GTPases. Small GTPases (2014) 1.09
Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2. Mol Cell Biol (2009) 1.08
Activation of TRPP2 through mDia1-dependent voltage gating. EMBO J (2008) 1.06
Molecular mechanisms of cell-cell spread of intracellular bacterial pathogens. Open Biol (2013) 1.04
Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J Biol Chem (2011) 1.04
Conformational changes in actin filaments induced by formin binding to the barbed end. Biophys J (2006) 1.04
Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function. Chem Rev (2014) 1.00
Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression. Small GTPases (2014) 0.98
Crystal structure of the Formin mDia1 in autoinhibited conformation. PLoS One (2010) 0.96
Actin monomers activate inverted formin 2 by competing with its autoinhibitory interaction. J Biol Chem (2013) 0.96
Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM. J Biol Chem (2010) 0.95
Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins. PLoS One (2010) 0.93
Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93
Diaphanous-related formin 2 and profilin I are required for gastrulation cell movements. PLoS One (2008) 0.93
Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains. Mol Biol Cell (2012) 0.91
Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors. Nat Struct Mol Biol (2014) 0.90
Apical targeting of the formin Diaphanous in Drosophila tubular epithelia. Elife (2013) 0.90
The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility. J Cell Biol (2013) 0.88
RhoA and DIAPH1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking. Endocrinology (2010) 0.87
Entamoeba histolytica encodes unique formins, a subset of which regulates DNA content and cell division. Infect Immun (2008) 0.87
Cdc42p regulation of the yeast formin Bni1p mediated by the effector Gic2p. Mol Biol Cell (2012) 0.87
Yeast formin Bni1p has multiple localization regions that function in polarized growth and spindle orientation. Mol Biol Cell (2011) 0.87
The role of formin tails in actin nucleation, processive elongation, and filament bundling. J Biol Chem (2014) 0.84
The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin. PLoS Biol (2015) 0.83
Cell-cycle regulation of formin-mediated actin cable assembly. Proc Natl Acad Sci U S A (2013) 0.83
Formin' cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics. Commun Integr Biol (2014) 0.82
Regulation of adrenocortical steroid hormone production by RhoA-diaphanous 1 signaling and the cytoskeleton. Mol Cell Endocrinol (2012) 0.81
Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies? Acta Crystallogr F Struct Biol Commun (2015) 0.81
Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription. Am J Physiol Heart Circ Physiol (2014) 0.81
Entamoeba histolytica Rho1 regulates actin polymerization through a divergent, diaphanous-related formin. Biochemistry (2012) 0.81
Actin engine in immunological synapse. Immune Netw (2012) 0.81
cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells. Mol Biol Cell (2013) 0.79
FMNL formins boost lamellipodial force generation. Nat Commun (2017) 0.78
Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers. Clin Exp Reprod Med (2011) 0.78
Formin' cables under stress. Nat Cell Biol (2013) 0.78
Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss. EMBO Mol Med (2016) 0.77
The final cut: cell polarity meets cytokinesis at the bud neck in S. cerevisiae. Cell Mol Life Sci (2016) 0.76
A role for the small GTPase Rac1 in vaccinia actin-based motility. Small GTPases (2014) 0.76
Ras GTPases' interaction with effector domains: Breaking the families' barrier. Commun Integr Biol (2013) 0.75
Structural and Biochemical Basis for the Inhibitory Effect of Liprin-α3 on Mouse Diaphanous 1 (mDia1) Function. J Biol Chem (2015) 0.75
Purification, crystallization and preliminary structural characterization of the N-terminal region of the human formin-homology protein FHOD1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.75
Small-molecule agonists of mammalian Diaphanous-related (mDia) formins reveal an effective glioblastoma anti-invasion strategy. Mol Biol Cell (2015) 0.75
A role for the small GTPase Rac1 in vaccinia actin-based motility. Small GTPases (2015) 0.75
Control of Formin Distribution and Actin Cable Assembly by the E3 Ubiquitin Ligases Dma1 and Dma2. Genetics (2016) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
Electrostatics of nanosystems: application to microtubules and the ribosome. Proc Natl Acad Sci U S A (2001) 42.14
Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr (2005) 29.38
Cellular motility driven by assembly and disassembly of actin filaments. Cell (2003) 26.05
Rho GTPases in cell biology. Nature (2002) 22.81
Efficient anisotropic refinement of macromolecular structures using FFT. Acta Crystallogr D Biol Crystallogr (1999) 15.91
Rapid measurement of binding constants and heats of binding using a new titration calorimeter. Anal Biochem (1989) 11.99
Main-chain bond lengths and bond angles in protein structures. J Mol Biol (1993) 9.80
The guanine nucleotide-binding switch in three dimensions. Science (2001) 9.34
Rho GTPases and their effector proteins. Biochem J (2000) 8.89
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat Cell Biol (1999) 5.84
Role of formins in actin assembly: nucleation and barbed-end association. Science (2002) 5.47
Mechanism of actin-based motility. Science (2001) 5.04
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J (1997) 5.03
A colorimetric method for determining low concentrations of mercaptans. Arch Biochem Biophys (1958) 4.87
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell (2000) 4.21
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis. Cell (2004) 4.01
Drosophila Spire is an actin nucleation factor. Nature (2005) 3.64
The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. Curr Biol (2003) 3.64
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Formin proteins: a domain-based approach. Trends Biochem Sci (2005) 3.45
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain. Nature (2005) 3.31
The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol (2003) 3.13
Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature (1999) 3.13
Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development (1994) 3.05
WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett (2002) 2.98
Crystal structure of a beta-catenin/Tcf complex. Cell (2000) 2.93
Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain. J Biol Chem (2000) 2.86
Actin polymerization-driven molecular movement of mDia1 in living cells. Science (2004) 2.80
Formin leaky cap allows elongation in the presence of tight capping proteins. Curr Biol (2003) 2.69
The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments. J Biol Chem (2004) 2.54
Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature (2005) 2.52
Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci (2003) 2.31
Phylogenetic analysis of the formin homology 2 domain. Mol Biol Cell (2004) 2.30
Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nat Cell Biol (2001) 2.27
Mechanism of formin-induced nucleation of actin filaments. Biochemistry (2003) 2.18
Structural basis of Rho GTPase-mediated activation of the formin mDia1. Mol Cell (2005) 2.16
The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. Mol Biol Cell (2002) 2.14
Formin-induced nucleation of actin filaments. Curr Opin Cell Biol (2004) 2.12
FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J (1997) 2.10
Spectrophotometric determination of protein concentration in cell extracts containing tRNA's and rRNA's. Anal Biochem (1973) 2.09
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem J (2004) 2.08
How capping protein binds the barbed end of the actin filament. Curr Biol (2003) 2.05
Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature (1999) 1.97
Dissecting requirements for auto-inhibition of actin nucleation by the formin, mDia1. J Biol Chem (2004) 1.90
Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.79
The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell (2004) 1.74
Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast. Mol Biol Cell (2005) 1.59
Thermodynamics of the interaction of barnase and barstar: changes in free energy versus changes in enthalpy on mutation. J Mol Biol (1997) 1.59
The active conformation of the PAK1 kinase domain. Structure (2005) 1.50
The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Mol Cell (1999) 1.40
Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. Nature (1995) 1.38
Localization of a mammalian homolog of diaphanous, mDia1, to the mitotic spindle in HeLa cells. J Cell Sci (2001) 1.33
A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting. J Mol Biol (2004) 1.32
The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein. Proc Natl Acad Sci U S A (2005) 1.31
Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J (2001) 1.17
Ras and its effectors. Prog Biophys Mol Biol (1996) 1.02
Progressing actin: Formin as a processive elongation machine. Nat Cell Biol (2004) 1.00
Rapid and efficient one-tube PCR-based mutagenesis method. Methods Mol Biol (1997) 0.92
The purification and crystallization of mDia1 in complex with RhoC. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.81
GEFs and GAPs: critical elements in the control of small G proteins. Cell (2007) 7.32
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science (2005) 5.99
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature (2013) 5.04
Structural insight into filament formation by mammalian septins. Nature (2007) 2.90
It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol (2009) 2.34
The complex of Arl2-GTP and PDE delta: from structure to function. EMBO J (2002) 2.24
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Cell (2011) 2.16
Structure and regulation of the cAMP-binding domains of Epac2. Nat Struct Biol (2003) 2.11
Capturing cyclic nucleotides in action: snapshots from crystallographic studies. Nat Rev Mol Cell Biol (2007) 2.07
The GTPase-activating protein Rap1GAP uses a catalytic asparagine. Nature (2004) 2.06
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol (2011) 2.00
How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature (2006) 1.92
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state. Nature (2006) 1.88
The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins. Nat Cell Biol (2011) 1.87
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element. EMBO J (2006) 1.75
The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell (2004) 1.74
A restricted spectrum of NRAS mutations causes Noonan syndrome. Nat Genet (2009) 1.71
Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy. Mol Cell (2007) 1.67
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex. EMBO J (2003) 1.67
The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3. Nat Struct Mol Biol (2008) 1.64
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
A new family of RhoGEFs activates the Rop molecular switch in plants. Nature (2005) 1.64
Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase. EMBO J (2008) 1.62
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. Proc Natl Acad Sci U S A (2004) 1.57
Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem (2003) 1.53
RanGAP mediates GTP hydrolysis without an arginine finger. Nature (2002) 1.50
Structural insights into HypB, a GTP-binding protein that regulates metal binding. J Biol Chem (2006) 1.47
Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J (2007) 1.38
Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J (2010) 1.35
GTP-induced conformational changes in septins and implications for function. Proc Natl Acad Sci U S A (2009) 1.35
Nucleotide binding and filament assembly of recombinant yeast septin complexes. Biol Chem (2005) 1.34
The structure of the TrmE GTP-binding protein and its implications for tRNA modification. EMBO J (2004) 1.34
The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy. Proc Natl Acad Sci U S A (2008) 1.30
Rap-specific GTPase activating protein follows an alternative mechanism. J Biol Chem (2002) 1.28
The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues. EMBO J (2008) 1.28
Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins. J Biol Chem (2007) 1.28
Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem (2008) 1.27
Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes. Angew Chem Int Ed Engl (2010) 1.25
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat (2010) 1.24
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins. J Biol Chem (2006) 1.22
Structural evidence for a common intermediate in small G protein-GEF reactions. Mol Cell (2007) 1.20
Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem (2003) 1.18
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex. FEBS Lett (2008) 1.17
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. EMBO J (2011) 1.16
Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3. Structure (2006) 1.15
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum. J Biol Chem (2006) 1.14
Reassessment of the role of FKBP38 in the Rheb/mTORC1 pathway. FEBS Lett (2009) 1.13
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. EMBO J (2012) 1.12
Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3. Proc Natl Acad Sci U S A (2009) 1.11
Perturbation of the conformational equilibria in Ras by selective mutations as studied by 31P NMR spectroscopy. FEBS Lett (2004) 1.08
Synthesis of the Rheb and K-Ras4B GTPases. Angew Chem Int Ed Engl (2010) 1.07
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein. Proc Natl Acad Sci U S A (2006) 1.06
Fluorescence methods in the study of small GTP-binding proteins. Methods Mol Biol (2002) 1.05
Structure of a 14-3-3σ-YAP phosphopeptide complex at 1.15 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 1.04
Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. Biochim Biophys Acta (2003) 1.02
Biochemical characterization of the Ran-RanBP1-RanGAP system: are RanBP proteins and the acidic tail of RanGAP required for the Ran-RanGAP GTPase reaction? Mol Cell Biol (2003) 1.02
Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger. J Biol Chem (2004) 1.02
The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism. Cell (2010) 1.02
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy. PLoS Biol (2009) 1.01
Molecular tweezers modulate 14-3-3 protein-protein interactions. Nat Chem (2013) 1.01
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc Natl Acad Sci U S A (2012) 0.99
Lipidated ras and rab peptides and proteins--synthesis, structure, and function. Angew Chem Int Ed Engl (2006) 0.99
The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo. EMBO Rep (2013) 0.98
Rho proteins of plants--functional cycle and regulation of cytoskeletal dynamics. Eur J Cell Biol (2011) 0.98
Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions. Cell (2013) 0.97
G-domain dimerization orchestrates the tRNA wobble modification reaction in the MnmE/GidA complex. J Mol Biol (2009) 0.97
A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected]. Mol Biol Cell (2010) 0.96
Unravelling the mechanism of dual-specificity GAPs. EMBO J (2010) 0.96
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol Cell Biol (2010) 0.95
Structure and function of Rho-type molecular switches in plants. Plant Physiol Biochem (2007) 0.95
Properties of the interaction of Arf-like protein 2 with PDEdelta. J Mol Biol (2005) 0.94
Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins. Biochemistry (2005) 0.93
Structural and biochemical properties of Sept7, a unique septin required for filament formation. Biol Chem (2011) 0.92
RPGR and RP2: targets for the treatment of X-linked retinitis pigmentosa? Expert Opin Ther Targets (2009) 0.91
Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42. J Biol Chem (2003) 0.91
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach. J Mol Biol (2006) 0.89
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGap interaction. Biol Chem (2008) 0.89
Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem (2010) 0.87
A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A. J Mol Biol (2009) 0.87
The crystal structure of the Ran-Nup153ZnF2 complex: a general Ran docking site at the nuclear pore complex. Structure (2008) 0.87
Human septin isoforms and the GDP-GTP cycle. Biol Chem (2014) 0.85
Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes. Proc Natl Acad Sci U S A (2012) 0.85
Stabilization of G domain conformations in the tRNA-modifying MnmE-GidA complex observed with double electron electron resonance spectroscopy. J Biol Chem (2010) 0.85
Arranged sevenfold: structural insights into the C-terminal oligomerization domain of human C4b-binding protein. J Mol Biol (2012) 0.85
Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives. Chembiochem (2014) 0.85
The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins. J Mol Biol (2008) 0.84
Fluorescently labelled guanine nucleotide binding proteins to analyse elementary steps of GAP-catalysed reactions. J Mol Biol (2002) 0.83
RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-specific nucleotide exchange. FEBS J (2009) 0.82
Actin filament bundling and different nucleating effects of mouse Diaphanous-related formin FH2 domains on actin/ADF and actin/cofilin complexes. J Mol Biol (2010) 0.81
The purification and crystallization of mDia1 in complex with RhoC. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.81
Synthesis of GTP-derived Ras ligands. Chembiochem (2004) 0.81
GTPase activity of Di-Ras proteins is stimulated by Rap1GAP proteins. Small GTPases (2010) 0.81
Systematic peptide array-based delineation of the differential beta-catenin interaction with Tcf4, E-cadherin, and adenomatous polyposis coli. J Biol Chem (2004) 0.80
Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction. J Am Chem Soc (2013) 0.79
Structural insights of the MLF1/14-3-3 interaction. FEBS J (2012) 0.79
Dimeric plant RhoGAPs are regulated by its CRIB effector motif to stimulate a sequential GTP hydrolysis. J Mol Biol (2011) 0.79
Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78