PubRank

Dirk Seegert

Author PubWeight™ 28.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sarcoidosis is associated with a truncating splice site mutation in BTNL2. Nat Genet 2005 4.23
2 Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet 2004 3.19
3 TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells. Gastroenterology 2003 2.58
4 The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets 2007 2.17
5 p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease. J Immunol 2002 2.14
6 Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model. Crit Care Med 2011 1.87
7 A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Proc Natl Acad Sci U S A 2006 1.37
8 Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood 2007 1.37
9 Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice. Arterioscler Thromb Vasc Biol 2011 1.29
10 The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression. J Biol Chem 2004 1.07
11 A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion. J Cell Sci 2008 1.03
12 N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130. J Biol Chem 2009 0.98
13 Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1. FASEB J 2004 0.97
14 Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130. J Biol Chem 2008 0.91
15 Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC. J Immunol 2011 0.90
16 Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients. Int J Colorectal Dis 2004 0.86
17 Differential p38 mitogen-activated protein kinase target phosphorylation in responders and nonresponders to infliximab. Gastroenterology 2003 0.84
18 Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis. Immunobiology 2012 0.83
19 Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells. J Biol Chem 2005 0.81
20 Are postoperative complications genetically determined by TNF-beta NcoI gene polymorphism? Surgery 2004 0.75